
Harnessing Endogenous Mechanisms for Targeted Drug Delivery
- 1st Edition - October 15, 2025
- Imprint: Academic Press
- Editors: Anisha A. D’Souza, Lara Scheherazade Milane, Mansoor M. Amiji
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 7 4 2 9 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 7 4 3 0 - 5
Harnessing Endogenous Mechanisms for Targeted Drug Delivery explores the cutting-edge advancements in the world of targeted drug delivery leveraging human biological mechan… Read more

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Request a sales quote- Provides comprehensive insights into endogenous strategies for targeted drug delivery
- Highlights innovative techniques like using cells as Trojan Horse-Cloaking Particles
- Explores the clinical and commercial translation of these strategies
- Offers practical solutions to contemporary challenges in the area
- Emphasizes the role of disease-specific stimuli and plasma proteins in drug delivery
1. Contemporary Drug Delivery Challenges
2. Delivery Barriers
3. Strategies for Targeted Drug Delivery
Section 2: Endogenous Strategies
4. Stimuli-Responsive Delivery
5. Glyco-Targeting using Lectins
6. Delivery using Plasma Proteins or Endogenous Peptides
7. Utilizing Virus Engineering in Drug Delivery
8. Living or artificial Cells as Trojan Horse-Cloaking Particles
9. Augmenting Cellular Cargo Capacity
10. Cell- and Bacterial-Derived Extracellular Vesicles-Based Targeted Delivery
11. Nucleic acid based delivery systems
Section 3: Clinical Translation
13. Challenges Associated with Endogenous Targeting – Preclinical to clinical, scalability, toxicity
14. Current Clinical Trials
15. Clinical and Commercial Translational Challenges
- Edition: 1
- Published: October 15, 2025
- Imprint: Academic Press
- No. of pages: 550
- Language: English
- Paperback ISBN: 9780443274299
- eBook ISBN: 9780443274305
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Anisha A. D’Souza
Dr. D’Souza is a Research Fellow at Massachusetts Eye and Ear Infirmary, Harvard Medical School, and is a Visiting Scholar at the Northeastern University, Department of Pharmaceutical Sciences, in Boston, MA. She earned her PhD (Tech.) in Pharmaceutics from the Department of Pharmaceutical Sciences and Technology at the Institute of Chemical Technology, Mumbai (ICT, formerly UDCT). Following her postdoctoral at IIT-Bombay, she served as a Research Formulation Scientist at Piramal Enterprises Limited, Mumbai. In this role, she contributed to projects achieving successful Abbreviated New Drug Application (ANDA) approvals by the US FDA. Dr. D’Souza’s research interests primarily revolve around colloidal drug delivery systems, viz., polymeric and solid lipid nanoparticles for enhanced bioavailability, controlled delivery and targeting. Additionally, she also explores nucleic acid delivery platforms for addressing CNS-related neurodegenerative disorders. She has published research papers and reviews in peer-reviewed journals, authored numerous book chapters, and co-edited a Springer-published book titled “Targeted Intracellular Drug Delivery by Receptor-Mediated Endocytosis”.
LM
Lara Scheherazade Milane
MA