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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Chemoarchitectonic Atlas of the Rat Brain

    • 3rd Edition
    • George Paxinos + 3 more
    • English
    The complement to The Rat Brain in Stereotaxic Coordinates, Chemoarchitectonic Atlas of the Rat Brain, Third Edition, features a single brain series of high-quality plates stained with eight different markers, extensively annotated and labelled throughout. Plates from the previous edition of Chemoarchitectonic Atlas of the Rat Brain have been re-scanned at high resolution and are shown in color. Labeled structures have been revised, corrected, and updated, providing users with a streamlined, up-to-date, and highly accurate compendium of chemical markers. Researchers with a need to understand the detailed organization of the rat brain as well as structure/function relationships will need this atlas and its array of stains.

  • Advanced Neuro MR Techniques and Applications

    • 1st Edition
    • Volume 4
    • In-Young Choi + 1 more
    • English
    Advanced Neuro MR Techniques and Applications gives detailed knowledge of emerging neuro MR techniques and their specific clinical and neuroscience applications, showing their pros and cons over conventional and currently available advanced techniques. The book identifies the best available data acquisition, processing, reconstruction and analysis strategies and methods that can be utilized in clinical and neuroscience research. It is an ideal reference for MR scientists and engineers who develop MR technologies and/or support clinical and neuroscience research and for high-end users who utilize neuro MR techniques in their research, including clinicians, neuroscientists and psychologists. Trainees such as postdoctoral fellows, PhD and MD/PhD students, residents and fellows using or considering the use of neuro MR technologies will also be interested in this book.

  • Essentials of Evidence-Based Practice of Neuroanesthesia and Neurocritical Care

    • 1st Edition
    • Hemanshu Prabhakar
    • English
    The current practice of medicine is largely moving toward applying an evidence-based approach. Evidence-based medicine is the integration of best research evidence using systematic reviews of the medical literature and then translating it into practice by selecting treatment options for specific cases based on the best research. Clinicians rely on the availability of evidence and accordingly take decisions to provide best treatment to their patients. Clinical management of neurologically compromised patients is challenging and varied; for this reason, treating physicians including neuroanesthesiologis... are always in search of best available evidence for patient management and care. Essentials of Evidence-Based Practice of Neuroanesthesia and Neurocritical Care highlights the various controversies that exist in the practice of neuroanesthesia and provides conclusive evidence-based solutions. This comprehensive resource succinctly discusses evidence-based practice of neuroanesthesia based on systematic reviews in clinical neuroscience research. Topics include neurophysiology: ICP or CPP thresholds; neuropharmacology: intravenous or inhalational anesthetics; and neuromonitoring: ICP monitoring. Evidence-based practice is now an integral part of neuroscience, and this book will help residents and trainees gain knowledge to apply it to their practice. Endorsements/Reviews... "Evidence based practice is facilitating changes at a rapid pace in neuroanesthesia and neurocritical care practice. Its practice is exceedingly crucial in neuroanesthesia and neurocritical care considering the criticality of the neurologically sick patients, which leaves little or no room for error for an acceptable outcome in them. Patient management in Neuroanesthesia and neurocritical care has many contentious issues because of rapidly evolving changes in their management which require treatment guided by the latest available evidence in literature. Dr. Hemanshu Prabhakar is a strong proponent of evidence based practice for the management of neurologically ill patients both for surgical procedures and their management in neurointensive care unit. Undoubtedly, this book will be of enormous benefits to the students as well as teachers of neuroanesthesia and neurocritical care sub-specialties." -- Parmod Bithal, Editor-In-Chief, Journal of Neuroanaesthesiology and Critical Care (JNACC)

  • Year One of Practice Transition

    The Necessary Guide to Success
    • 1st Edition
    • Jason E. Pope + 1 more
    • English
    Year One of Practice Transition: The Necessary Guide to Success is a practical guide for both established physicians transitioning from one practice opportunity to another, and those transitioning from formal residency or fellowship training. This book is an up-to-date look at how to achieve a successful practice, offering insights from top experts who have navigated transition through various phases and circumstances.

  • Foundations of Sleep Health

    • 1st Edition
    • F. Javier Nieto + 1 more
    • English
    Foundations of Sleep Health presents sleep health as a critical element of overall individual and population health. Sleep disorders are an increasing problem plaguing more than 40 million Americans. Sleep impacts numerous biological functions and plays a critical role in brain development, including learning and memory consolidation, cognitive functioning, and emotion regulation. This book provides an historic and current overview of the state of sleep health with an emphasis on the interplay between several levels of determinants and factors that influence sleep health. The text provides students in the health professions with in-depth discussion on the theory, research, and practice of sleep health, while also detailing mechanisms, hypotheses, and determinants of sleep and ways to improve sleep health.

  • Treatments, Mechanisms, and Adverse Reactions of Anesthetics and Analgesics

    • 1st Edition
    • Rajkumar Rajendram + 3 more
    • English
    Treatments, Mechanisms, and Adverse Reactions of Anesthetics and Analgesics is an essential read for anyone working in pain management. The book addresses the onset of pain, the cause of the pain, and the administration of analgesia or anesthesia. The etiology of pain is complex and multi-factorial, which is made more complex with the use of analgesics and local or general anesthetics. This volume works to clarify all of the subjects pertinent to anesthesia and the brain, from their variety, modes of action, and adverse effects.

  • The Neurobiology, Physiology, and Psychology of Pain

    • 1st Edition
    • Rajkumar Rajendram + 3 more
    • English
    The Neurobiology, Physiology and Psychology of Pain focuses on bettering readers’ understanding of acute and chronic pain. Featuring chapters on neurotransmitters, pharmacology, and brain imaging, this volume discusses, in detail, the mechanisms of pain and experimental studies undertaken to better understand the pathways involved. The translational work in this area has applicability for neurologists, anesthesiologists, pharmacologists, and anyone working in the intersection of these areas. This volume is integral for anyone interested in the molecular underpinnings of pain at every level.

  • Features and Assessments of Pain, Anesthesia, and Analgesia

    • 1st Edition
    • Rajkumar Rajendram + 3 more
    • English
    Features and Assessments of Pain, Anaesthesia and Analgesia examines the syndromes of pain and how they interlink with anesthesia and analgesics. The book covers assessments, screening and resources, and provides applications to related areas of medicine. It explores how the perception of pain results from a multifaceted interaction between illness beliefs, age, gender, time of onset, stress, socioeconomic status, and any number of other factors. In addition, the book scrutinizes how the neuroscience of pain in one condition may be relevant to understanding pain observed in other conditions.

  • Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS: Part II

    • 1st Edition
    • Volume 161
    • English
    Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS: Part II, Volume 161, in the International Review on Neurobiology serial highlights new advances, with this volume presenting chapters on topics including Introduction to Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS, Peri-adolescent Exposure to (Meth)amphetamine in Animal Models, The Impact of Adolescent Nicotine Exposure on Alcohol Use During Adulthood: The Role of Neuropeptides, Cannabis Exposure During Adolescence: A uniquely Sensitive Period for Neurobiological Effects, The Stoned Age: Sex Differences in the Effects of Adolescent Cannabinoid Exposure on Prefrontal Cortex Structure and Function in Animal Models, and more.

  • TDP-43 and Neurodegeneration

    From Bench to Bedside
    • 1st Edition
    • Vijay Kumar + 1 more
    • English
    Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders.

  • Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS Part I

    • 1st Edition
    • Volume 160
    • English
    Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS, Volume 161 in the International Review on Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Cannabis Exposure During Adolescence: A Uniquely Sensitive Period for Neurobiological Effects, The Stoned-Age: A Systematic Review of the Neurobiological Effects of Adolescent Cannabinoid Exposure on Preclinical Animal Models, Genetic Influences Impacting Nicotine Use and Abuse During Adolescence: Insights from Human and Animal Studies, the Impact of Adolescent Nicotine Exposure on Adulthood Alcohol Consumption: The Role of Neuropeptides, and much more. Additional chapters cover The Role of Sex in the Persistent Effects of Adolescent Alcohol Exposure on Behavior and Neurobiology in Rodents, The Effects of Peri-Adolescent Alcohol Use on the Developing Hippocampus, Regulation of Glutamate Signaling in the Extended Amygdala by Adolescent Alcohol Exposure, Peri-Adolescent Binge Drinking Effects on Hippocampal Neurogenesis, Neuroepigenetic Consequences of Adolescent Ethanol Exposure, Adolescent Neuroimmunity and Its Interaction with Alcohol, and much more.

  • Spinal Cord Injury Pain

    • 1st Edition
    • Christine N. Sang + 1 more
    • English
    Spinal Cord Injury Pain presents the basis for preclinical and clinical investigations, along with strategies for new approaches in the treatment of central neuropathic pain. Contributors from the private sector and academia provide a comprehensive review of state-of-the-art research in this challenging space. Topics include Epidemiology of Chronic Pain Following SCI, experimental models and mechanisms of chronic pain in SCI, and new targets and technologies. This book serves as a resource for continued translational research that will result in novel approaches and treatments that improve function and quality of life for individuals with CNP/SCI. Despite a better understanding of the complexity of mechanisms of CNP/SCI, improved medical and surgical management of SCI, and the subsequent acceleration of the identification of new targets and the development of novel analgesics, there is still a great unmet clinical need in the area of CNP following SCI. Hence, this book is a welcomed addition to current research and developments.

  • Comorbilidad en trastornos psicóticos

    Hacia una mejora del diagnóstico y el abordaje
    • 1st Edition
    • André Barciela Veras + 1 more
    • Spanish
    Obra que detalla con gran pericia los datos que respaldan un innovador enfoque para subclasificar la esquizofrenia y otros trastornos psicóticos en base a las comorbilidades de ansiedad y depresión. Proporciona casos prácticos simulados, criterios diagnósticos del DSM-5, modelos de entrevista específicos para cada una de las cinco comorbilidades en pacientes con psicosis y opciones terapéuticas mejoradas. También se analizan las psicosis relacionadas con el consumo de sustancias, las enfermedades médicas y el tratamiento médico, así como otros factores que contribuyen a los trastornos psicóticos. Esta pionera obra de referencia, única en su área, es un recurso clínico, docente, de investigación y de formación, útil para psiquiatras, psicólogos, profesionales de enfermería, trabajadores sociales, neurólogos y cualquiera que esté interesado en la asistencia y el tratamiento de pacientes con trastornos psicóticos. La obra incluye ejemplos de entrevistas con los pacientes y/o purebas de laboratorio para cada diagnóstico. Detalla los síntomas, cuasipsicóticos y los signos secundarios de las comorbilidades, tanto cuando aparecen de forma aislada como asociados a psicosis. Subraya el significado específico de cada diagnóstico y los papeles contribuyentes de los neurotransmisores, la hipofrontalidad, los traumas psicológicos y la genética.

  • Pediatric Headache

    • 1st Edition
    • Jack Gladstein + 2 more
    • English
    Covering the topic of headache in children from the viewpoint of both primary care and neurology, Pediatric Headache provides concise, authoritative guidance on all aspects of this multifaceted subject. Drs. Jack Gladstein, Christina Szperka, and Amy Gelfand, each an expert in pediatric headache, contribute their considerable knowledge and expertise to assist neurologists, pediatricians, and primary care providers in providing optimal care to young patients.

  • Methodological Approaches for Sleep and Vigilance Research

    • 1st Edition
    • Eric Murillo-Rodriguez
    • English
    Methodological Approaches for Sleep and Vigilance Research examines experimental procedures used to study the sleep-wake cycle, with topics covered by world leaders in the field. The book focuses on techniques commonly used in the sleep field, including polysomnography, electrophysiology, single- and multi-unit spiking activity recording, brain stimulation, EEG power spectra, optogenetics, telemetry, and wearable and non-wearable tracking devices. Further chapters on imaging techniques, questionnaires for sleep assessment, genome-wide association studies, artificial intelligence and big data are also featured. This discussion of significant conceptual advances into experimental procedures is suitable for anyone interested in the neurobiology of sleep.

  • Electromyography, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 39-4
    • Devon I. Rubin
    • English
    This issue of Neurologic Clinics, guest edited by Dr. Devon I. Rubin, will cover key topics in Electromyography. This issue is one of four selected each year by our series consulting editor, Dr. Randolph W. Evans. Topics discussed in this issue will include: Nerve Conduction Studies, Needle EMG, Electrodiagnostic Assessment of Uncommon Mononeuropathies, EDX Assessment of Uncommon Mononeuropathies, Electrodiagnostic Assessment of Radiculopathies, Electrodiagnostic Assessment of Plexopathies, Electrodiagnostic Assessment of Polyneuropathy, Electrodiagnostic Assessment of Myopathy, Electrodiagnostic Assessment of Neuromuscular Junction Disorders, Electrodiagnostic Assessment of Motor Neuron Diseases, Electrodiagnostic Assessment of Hyperexcitable Nerve Disorders, and EMG Case Examples.　

  • Nanomedicine and Neuroprotection in Brain Diseases

    • 1st Edition
    • Volume 265
    • Hari Shanker Sharma + 1 more
    • English
    Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Regulating Neuroscience: Transnational Legal Challenges

    • 1st Edition
    • Volume 4
    • English
    The Volume Regulating Neuroethics: Transnational Legal challenges will focus on the new and fascinating ethical and legal challenges posed by neurotechnology and its global regulation. The Volume will address topics ranging from the foundations of neuroethics, free will and human liberty to their impact in criminal and civil liability, the legal regulation of biotechnological developments and its challenges for health, privacy and other fundamental human rights.

  • Neuroinflammation, Resolution, and Neuroprotection in the Brain

    • 1st Edition
    • Akhlaq A. Farooqui
    • English
    Neuroinflammation, Resolution, and Neuroprotection in the Brain discusses the molecular aspects of neuroinflammation in neurological disorders. The book examines the effect of diet and exercise on neuroinflammatory diseases. Chapters focus on bioactive lipids, cytokines and chemokines, as well as the involvement of neuroinflammation, resolution and neuroprotection in neurotraumatic diseases, neurodegenerative diseases and neuropsychiatric diseases. The comprehensive information in this monograph will help readers understand molecular cross-talk among mediators of phospholipid, sphingolipid and cholesterol metabolism. The book's goal is to jumpstart more studies on molecular mechanisms and the therapeutic aspects of neurological disorders in human subjects.

  • Connectomic Deep Brain Stimulation

    • 1st Edition
    • Andreas Horn
    • English
    Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson’s Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery.

  • Novel Psychoactive Substances

    Classification, Pharmacology and Toxicology
    • 2nd Edition
    • Paul I. Dargan + 1 more
    • English
    Novel Psychoactive Substances: Classification, Pharmacology and Toxicology, Second Edition provides readers with a comprehensive examination on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." The book covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance and a discussion of their associated acute and chronic harm and toxicity. This second edition addresses drugs new to the scene, with completely updated and revised chapters. Written by international experts in the field, this multi-authored book is an essential reference for scientists, clinicians, academics, and regulatory and law enforcement professionals.

  • Encyclopedia of Behavioral and Cognitive Neuroscience

    • 2nd Edition
    • Sergio Della Sala
    • English
    Behavioral Neuroscience is a relatively recent discipline which unifies different fields encompassing Cognitive Psychology, Cognitive Science, Clinical Neurology, Neuroanatomy, and Neurophysiology. Encyclopedia of Behavioral Neuroscience, Three Volume Set is a comprehensive, multidisciplinary work written by the best experts in the field, addressing the relationship between the neurological and biological basis of behavior and models of cognition, spanning from perception to memory and covering phenomena that occur in human and other animals. Published in 2010, it comprised 212 articles and was a unique and essential resource for students and professionals in several fields including neuroscience, psychology, neurology, psychiatry, and cognitive science. It was by far the most comprehensive reference work available addressing the advances in all the field of behavioral neuroscience. It does however, now need revising with the latest science. The new edition will again cover the relationship between brain and behavior, both in humans and other animals, as well as mental and brain disorders. This new edition spans accross three volumes, 250 chapters and approximately 2000 pages. It will build on the foundations of the first edition by thoroughly updating all current articles with the latest research that has developed in the last decade. In addition, 40 brand new articles on the hottest topics within behavioral neuroscience will be added, covering areas such as advances in behavioral genetics and epigenetics, cognitive ageing, neuroepidemiology, social neuroscience, as well as the upsurge of new technologies like diffusion tensor imaging or transcranial direct current stimulation. The result will be an all-encompassing one-stop interdisciplinary major reference work on how the brain and its disorders influence behavior, perfect for neuroscience students, clinicians and scientists interested in knowing more about behavior from a biological perspective.

  • Alzheimer's Disease

    Understanding Biomarkers, Big Data, and Therapy
    • 1st Edition
    • Ahmed Moustafa
    • English
    Nearly 44 million people have Alzheimer’s or related dementia worldwide, according to the Alzheimer’s Disease International organization. That number is expected to double every 20 years. Unlike other books on the market, Alzheimer's Disease: Understanding Biomarkers, Big Data, and Therapy covers recent advancements in cognitive, clinical, neural, and therapeutic aspects of Alzheimer’s and other forms of dementia.First, readers are introduced to cognitive and clinical studies, focusing on the different types of memory impairment, past and future thinking. This includes the prevalence of depression, its relationship to other symptoms, and the quality of life for those with Alzheimer’s disease. In addition, the book discusses recent studies on memory dysfunction in advanced-stage Alzheimer’s disease, in comparison to early-stage, including a chapter on the underlying factors in the transition from mild cognitive impairment to Alzheimer’s diagnosis. Following this section, the book presents recent studies on the role of different cortical and subcortical structures in the development of various symptoms in Alzheimer’s disease, as well as different neural biomarkers underlying the development and treatment of the disease. In the last section of the book, therapeutic aspects of Alzheimer’s disease, focusing on behavioral and pharmacological treatments of sleep disorders, memory problems, and depression, are reviewed. The book aids readers in understanding the advances in research and care, making it a prime tool for all clinicians, psychologists, researchers, neurologists, and caregivers of dementia patients.

  • The Neurobiology of Aging and Alzheimer Disease in Down Syndrome

    • 1st Edition
    • Elizabeth Head + 1 more
    • English
    The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena.

  • Child Neurology

    Its Origins, Founders, Growth and Evolution
    • 2nd Edition
    • Stephen Ashwal
    • English
    Child Neurology: Its Origins, Founders, Evolution and Growth, Second Edition updates the first biographical study of important contributors to the field of child neurology, consisting of over 250 biographical sketches written by over 100 physicians specializing in neurology, child neurology, pediatrics and obstetrics. Organized chronologically into six chapters, beginning before 1800 and continuing to the present, Child Neurology traces the emergence of child neurology as a separate specialty from its roots in pediatrics and neurology. With a definitive historical introduction by the editor, Dr. Stephen Ashwal. This new edition will feature a new section on The Dynamic Growth and Expansion of Child Neurology: The Late Twentieth Century (1960 to 2000+) and features about 138 new biographical sketches of leaders in the field during this recent time frame. Child Neurology: Its Origins, Founders, Evolution and Growth, Second Edition will be published on behalf of the Child Neurology Society, a professional society that strives to foster recognition and support for children with neurological disorders and to promote and exchange national and international scientific research, education, and training in the field of neurology.

  • Neurological Care and the COVID-19 Pandemic

    • 1st Edition
    • Ahmad Riad Ramadan + 1 more
    • English
    Offering a comprehensive review of the neuropathology of SARS-CoV-2, Neurological Care and the COVID-19 Pandemic provides up-to-date coverage of the wide array of the pathogen’s neurological symptoms and complications. Drs. Ahmad Riad Ramadan and Gamaledin Osman discuss the neuropathology of SARS-CoV-2, its neurological manifestations, and the impact the pandemic has had on the care of patients with pre-existing neurological conditions. The authors also offer an overview of emerging treatments and vaccines, as well as ways healthcare systems have reorganized in order to respond to the pandemic.

  • Emerging Horizons in Neuromodulation: New Frontiers in Brain and Spine Stimulation

    • 1st Edition
    • Volume 159
    • English
    International Review of Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Fundamentals of Pediatric Imaging

    • 3rd Edition
    • Lane F. Donnelly
    • English
    Fundamentals of Pediatric Imaging, Third Edition presents the foremost techniques of pediatric medical image analysis and processing. It includes advanced imaging techniques, neuro applications, and highlights basic anatomy needed to understand this complex specialty. The book introduces the theory and concepts of pediatric digital image analysis and newly revised information on quality and safety topics, imaging modalities, imaging applications, and new discoveries in diseases and treatments. The newly revised edition provides updates in areas of expertise including neurologic, musculoskeletal, cardiac, chest, and GU imaging. Edited by Lane F. Donnelly, MD, recipient of the Society of Pediatric Radiology’s 2009 Singleton-Taybi Award, this book is sure to be a prime reference in pediatric medical imagining.

  • Disorders of Emotion in Neurologic Disease

    • 1st Edition
    • Volume 183
    • English
    Disorders of Emotion in Neurologic Disease, Volume 183 in the Handbook of Clinical Neurology Series, informs clinicians on which neurologic diseases are likely to have a secondary effect on emotion, what to look for in diagnosis, and best practices for treatment. The book begins with an understanding of the neurological basis for emotions in order to better understand what goes awry in neurological disease. It then discusses specific neurologic diseases and disorders affecting emotion.

  • Retinal Computation

    • 1st Edition
    • Greg Schwartz
    • English
    Retinal Computation summarizes current progress in defining the computations performed by the retina, also including the synaptic and circuit mechanisms by which they are implemented. Each chapter focuses on a single retinal computation that includes the definition of the computation and its neuroethological purpose, along with the available information on its known and unknown neuronal mechanisms. All chapters contain end-of-chapter questions associated with a landmark paper, as well as programming exercises. This book is written for advanced graduate students, researchers and ophthalmologists interested in vision science or computational neuroscience of sensory systems. While the typical textbook's description of the retina is akin to a biological video camera, the real retina is actually the world’s most complex image processing machine. As part of the central nervous system, the retina converts patterns of light at the input into a rich palette of representations at the output. The parallel streams of information in the optic nerve encode features like color, contrast, orientation of edges, and direction of motion. Image processing in the retina is undeniably complex, but as one of the most accessible parts of the central nervous system, the tools to study retinal circuits with unprecedented precision are up to the task. This book provides a practical guide and resource about the current state of the field of retinal computation.

  • Chirurgie endoscopique endonasale

    • 1st Edition
    • Patron Vincent + 1 more
    • French
    La chirurgie endoscopique endonasale est une chirurgie récente, dont la réputation était, encore il y a quelques années, celle d’une « chirurgie aveugle et aveuglante » tant ses complications pouvaient être graves et fréquentes. Aujourd’hui les progrès techniques et technologiques permettent d’améliorer la plupart des pathologies nasosinusiennes avec des suites opératoires simples. Pourtant, nombre de chirurgiens limitent toujours leur pratique aux procédures élémentaires par méconnaissance des techniques actuelles. Très didactique et richement illustré, ce livre apportera au praticien toutes les connaissances anatomiques, radiologiques et techniques nécessaires pour réaliser l’ensemble des procédures endoscopiques courantes. Chaque intervention y est décrite « pas à pas », depuis la préparation de l’intervention jusqu’aux suites opératoires. Une iconographie abondante et de nombreux conseils pratiques en font un ouvrage au plus proche de l’enseignement de terrain réalisé au bloc opératoire. L’ouvrage est complété par de nombreuses vidéos en ligne

  • Sex and Gender Differences in Alzheimer's Disease

    • 1st Edition
    • Maria Teresa Ferretti + 2 more
    • English
    Sex and Gender Differences in Alzheimer’s Disease: The Women’s Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer’s disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer’s disease families, in the frame of a precision medicine approach to Alzheimer’s disease.This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer’s disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer’s a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer’s disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer’s disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Endorsements/Reviews... "There is a clear sex and gender gap in outcomes for brain health disorders like Alzheimer’s disease, with strikingly negative outcomes for women. This understanding calls for a more systematic way of approaching this issue of inequality. This book effectively highlights and frames inequalities in all areas across the translational spectrum from bench-to-bedside and from boardroom-to-policy and economics. Closing the Brain Health Gap will help economies create recovery and prepare our systems for future global shocks." Harris A. Eyre MBBS, PhD, co-lead, Neuroscience-inspire... Policy Initiative, OECD and PRODEO Institute. Instructor in Brain Health Diplomacy, Global Brain Health Institute, UCSF and TCD. "Sex and Gender Differences in Alzheimer's disease is the most important title to emerge on Alzheimer's disease in recent years.This comprehensive, multidisciplinary book is a must read for anyone with a serious interest　in dementia prevention, diagnosis, treatment, care, cure and research. Precision medicine is the future of healthcare and this book represents an incredible and necessary resource to guide practice, policy and research in light of the fact that Alzheimer's disease disproportionately affects women. The combination of contributions from the most eminent experts and the most up-to-date research makes this an invaluable resource for clinicians, care providers, academics, researchers and policy makers. Given the complex nature of dementia and the multiple factors that influence risk and disease trajectory the scope of the book is both impressive and important covering sex differences in neurobiological processes, sex and gender differences in clinical aspects and gender differences linked to socioeconomic factors relevant to Alzheimer's disease. If you work in Alzheimer's disease, or indeed other dementias, then Sex and Gender Differences in Alzheimer's disease is a must have for your bookshelf." -- Sabina Brennan, PhD., C.Psychol.,PsSI., National representative for Ireland on Alzheimer Disease International's Medical and Scientific Advisory Panel

  • Teleneurology

    Complete Guide to Implementing Telemedicine and Telebehavioral Health into Your Practice
    • 1st Edition
    • Randall Wright
    • English
    In today’s changing medical climate, more physicians than ever before are incorporating telemedicine into their clinical practice. Teleneurology provides comprehensive, practical answers to the many questions clinicians have on implementing and growing a teleneurology practice. Covering everything from historical perspectives to future possibilities in this evolving field, it provides the information you need to successfully use this promising new option in providing optimal and adaptable patient care.

  • Marine Neurotoxins

    • 1st Edition
    • Volume 6
    • English
    Marine Neurotoxins, Volume Five provides comprehensive information on marine toxins present in the human food chain and the affecting targets relevant for the functioning of the brain and our nervous system, covering all the information available on their action on the physiology of neurons and glial cells, both "in vivo" or "in vitro." New sections in this release include Guanidinium Toxins: Evolution, Mode of Action and Chemical Ecology, Amnesic: Domoic Acid, Neurotoxic: Ciguatoxin and Brevetoxin, Neurotoxic: Cyclic Imines, Potentially Neurotoxic: Okadaic acid and analogues, Potentially Neurotoxic: Palytoxin, and Methods for assessing the presence of marine neurotoxins.

  • Pediatric Neurology, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 39-3
    • Gary Clark + 1 more
    • English
    This issue of Neurologic Clinics, guest edited by Drs. Gary D. Clark and James J. Riviello, will cover key topics in Pediatric Neurology. This issue is one of four selected each year by our series consulting editor, Dr. Randolph W. Evans. Topics discussed in this issue will include: The State of Child Neurology; The Financial Power of Neurology in a Major Children’s Hospital; Neurology in a Pandemic; Education: Training the Next Generation of Child Neurologists and Neurodevelopmental Disability Doctors, Student Education and Recruitment; Genetic Testing and Counseling in Child Neurology; Novel Treatments and Clinical Research in Child Neurology; Epilepsy: Novel Surgical Techniques and Monitoring; Epilepsy: Genetics; Epilepsy: Treatment of Epileptic Syndromes; Neuromodulation for Pediatric Epilepsy; Inflammatory Diseases of the Nervous System; Neurooncology; Neurocritical Care and Brain Monitoring; The Brain and Heart Disease in Children; Neurology of Sleep; and Evidence Based Protocols. 　 　 　

  • Thyroid and Parathyroid Imaging, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 31-3
    • Salmaan Ahmed + 1 more
    • English
    In this issue of Neuroimaging Clinics, guest editors Salmaan Ahmed and J. Matthew Debnam bring their considerable expertise to the topic of Thyroid and Parathyroid Imaging.

  • Alcohol

    Neurobiology of Addiction
    • 1st Edition
    • Volume 3
    • George F. Koob + 3 more
    • English
    A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Alcohol, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/antici...

  • The Human Hypothalamus

    Neuropsychiatric Disorders
    • 1st Edition
    • Volume 182
    • Dick F. Swaab + 4 more
    • English
    The Human Hypothalamus: Neuropsychiatric Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume identifies the neurobiology and neurophysiology of disorders relating to the hypothalamus and provides treatment information for these disorders. Disorders covered include neuropsychiatric, neurodegenerative, periodic, and autoimmune disorders. Coverage includes Alzheimer’s, Parkinson’s, epilepsy, sleep, pain, depression, anxiety, OCD, PTSD, schizophrenia, autism, aggressions, addiction, and more.

  • Stereotaxic Brain Atlas of the Egyptian Fruit Bat

    • 1st Edition
    • Raya Eilam-Altstadter + 3 more
    • English
    The Stereotaxic Brain Atlas of the Egyptian Fruit Bat provides the first stereotaxic atlas of the brain of the Egyptian fruit bat (Rousettus aegyptiacus), an emerging model in neuroscience. This atlas contains coronal brain sections stained with cresyl violet (Nissl), AChE, and Parvalbumin – all stereotaxically calibrated. It will serve the needs of any neuroscientist who wishes to work with these bats – allowing to precisely target specific brain areas for electrophysiology, optogenetics, pharmacology, and lesioning. More broadly, this atlas will be useful to all neuroscientists working with bats, as it delineates many brain regions that were not delineated so far in any bat species. Finally, this atlas will provide a useful resource for researchers interested in comparative neuroanatomy of the mammalian brain.

  • The Human Hypothalamus

    Neuroendocrine Disorders
    • 1st Edition
    • Volume 181
    • Dick F. Swaab + 4 more
    • English
    The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume summarizes the role of the hypothalamus in neuroendocrine disorders, identifying the mechanism of action, disorder etiology, and best practices for assessment and treatment. Disorders covered include pituitary hypothalamic disorders of development and growth, hypothalamic tumor related disorders, hypothalamic autoimmune disorders and infection, disorders of vasopressin, water and sodium homeostasis, eating disorders, and gonadotropic hormone regulation disorders.

  • The Human Hypothalamus

    Middle and Posterior Region
    • 1st Edition
    • Volume 180
    • Dick F. Swaab + 4 more
    • English
    The Hypothalamus is an important area of the brain for understanding a variety of neurological disorders. This volume summarizes for readers the anatomy and physiology of the middle and posterior hypothalamus, to better understand pathology and treatment of hypothalamus related disorders. In addition to anatomy and physiology in humans, cytoarchitecture and chemoarchitecture in rodents is provided. The volume explores the role of the hypothalamus in disorders of eating, sleeping, anxiety, and mood, as well as its role in sexual behavior and gender identity. Coverage includes how Parkinson’s, Alzheimer’s and other neurological disorders relate to the hypothalamus.

  • Neuromuscular Disorders

    Treatment and Management
    • 2nd Edition
    • Tulio E. Bertorini
    • English
    Offering an authoritative, multidisciplinary approach to the complex issues associated with neuromuscular disease, Neuromuscular Disorders, 2nd Edition, provides the latest tools and strategies for minimizing disability and maximizing quality of life. Dr. Tulio Bertorini, an expert in clinical neuromuscular care, and a team of world-renowned contributors cover all management and therapeutic considerations regarding the full range of neuromuscular disorders and resulting complications.

  • Zika Virus Biology, Transmission, and Pathways

    Volume 1: The Neuroscience of Zika Virus
    • 1st Edition
    • Colin R. Martin + 3 more
    • English
    Zika Virus Biology, Transmission, and Pathways: The Neuroscience of Zika, Volume One provides a detailed introduction to the molecular biology of the Zika virus and its features, transmission, and impact on neurological systems. Designed to better readers’ understanding of the Zika virus, this volume features chapters on the immune response, molecular mechanisms, and other areas to better understand underlying pathways. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions.

  • Zika Virus Impact, Diagnosis, Control, and Models

    Volume 2: The Neuroscience of Zika Virus
    • 1st Edition
    • Colin R. Martin + 3 more
    • English
    Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome. The book also details the neuroscience of Guillain-Barré syndrome, its effects and neuromuscular rehabilitation. It is designed to help readers better understand detection, therapies for Zika virus, preventative vaccines, diagnosis and associated microcephaly. Chapters on models enable further research and understanding. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions.

  • The Neuroscience of Aging

    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging is a comprehensive reference on the diagnosis and management of neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. It also examines pharmacological and non-pharmacological interventions of age-related conditions that affect the brain including Alzheimer’s, stroke, and multiple sclerosis. Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. It also examines the use of animal modelling of aging and neurological disease.

  • Non-invasive Brain Stimulation (NIBS) in Neurodevelopmental Disorders

    • 1st Edition
    • Volume 264
    • English
    Non-invasive Brain Stimulation (NIBS) in Neurodevelopmental Disorders, Volume 264 presents the latest updates on recent techniques used to examine the potential treatment of psychiatric and neurological disorders in adults. In this special issue, the book's authors and contributors provide a unique focus on the potential effects of non-invasive brain stimulation. Topics cover a range of reviews, opinions, methodologies, original research articles, and suggestions on how to better translate scientific knowledge into practice. This new release will help guide basic research and the development of therapeutic interventions for children and adolescents who suffer from neurodevelopmental disorders.

  • The Human Hypothalamus

    Anterior Region
    • 1st Edition
    • Volume 179
    • Dick F. Swaab + 4 more
    • English
    The Hypothalamus is an important area of the brain for understanding a variety of neurological disorders. This volume summarizes for readers the anatomy and physiology of the anterior hypothalamus, to better understand pathology and treatment of hypothalamus related disorders. In addition to anatomy and physiology in humans, cytoarchitecture and chemoarchitecture in rodents is provided. The volume explores the role of the hypothalamus in disorders of eating, sleeping, anxiety, and mood, as well as its role in sexual behavior and gender identity. Coverage includes how Parkinson’s, Alzheimer’s and other neurological disorders relate to the hypothalamus.

  • Cognitive and Behavioral Dysfunction in Schizophrenia

    • 1st Edition
    • Ahmed Moustafa
    • English
    According to the World Health Organization, schizophrenia affects more than 21 million people worldwide, causing distortions in thinking, perception, emotions, language, sense of self, behavior, and hallucinations. Cognitive and Behavioral Dysfunction in Schizophrenia provides an overview of topics and theories related to cognitive dysfunction in schizophrenia. This book discusses what schizophrenia is and its relationship with the cognitive domains including, but not limited to, learning, working memory, attention, and both deductive and inductive reasoning. This book also reviews theories as to why some individuals develop schizophrenia following cannabis and amphetamine abuse and how these relate to additional cognitive problems. The book further discusses recent topics related to religious delusions in psychotic patients, impact of sleep on psychosis, how urban life increases the likelihood of developing schizophrenia, as well as sexual dysfunction in schizophrenia patients. Unlike other books, Cognitive and Behavioral Dysfunction in Schizophrenia covers many cognitive domains related to the occurrence and development of positive and negative symptoms of schizophrenia. Advanced students and researchers in cognitive and behavioral neuroscience, psychology, psychiatry, and psychotherapy will find it useful for a well-rounded understanding of the subject.

  • Clinical Studies and Therapies in Parkinson's Disease

    Translations from Preclinical Models
    • 1st Edition
    • Juan Segura-Aguilar
    • English
    More than 50 years have passed since the use of L-dopa in the palliative treatment of Parkinson’s disease, but it remains the most common treatment despite inducing severe side effects such as dyskinesia after 4–6 years of use. Numerous preclinical investigations based on endogenous neurotoxin models have promised various therapies for Parkinson’s disease, but these efforts have failed　when attempting to transfer these successful results to preclinical studies. Although several publications have warned of these failures, the scientific community remains mostly unaware, and there is a need to focus their efforts on potential therapeutics that can slow or halt development of the disease.Clinical Studies and Therapies in Parkinson’s Disease: Translations from Preclinical Models analyzes preclinical models based on exogenous neurotoxins and why they have failed. Neuroscientists, neurologists, and neuropharmacologists will benefit greatly from the book’s discussion of these newer models, their benefits, and the need for their implementation. This book also provides the basic concepts of dopamine metabolism for students taking courses in neurochemistry, neuroscience, neuropharmacology, biochemistry, and medicine.

  • Big Data in Psychiatry and Neurology

    • 1st Edition
    • Ahmed Moustafa
    • English
    Big Data in Psychiatry and Neurology provides an up-to-date overview of achievements in the field of big data in Psychiatry and Medicine, including applications of big data methods to aging disorders (e.g., Alzheimer’s disease and Parkinson’s disease), mood disorders (e.g., major depressive disorder), and drug addiction. This book will help researchers, students and clinicians implement new methods for collecting big datasets from various patient populations. Further, it will demonstrate how to use several algorithms and machine learning methods to analyze big datasets, thus providing individualized treatment for psychiatric and neurological patients. As big data analytics is gaining traction in psychiatric research, it is an essential component in providing predictive models for both clinical practice and public health systems. As compared with traditional statistical methods that provide primarily average group-level results, big data analytics allows predictions and stratification of clinical outcomes at an individual subject level.

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