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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Cerebral Palsy

    A Clinical and Neuropathological Study
    • 1st Edition
    • Erna Christensen + 1 more
    • English
    Cerebral Palsy: A Clinical and Neuropathological Study is an account of a detailed study in which obstetrical, neonatal and neurological investigations on a large group of patients are presented with full neuropathological data found at subsequent necropsy. The book discusses the general autopsy findings and neuropathological techniques; as well as neuropathological findings in the different clinical entities. The text also describes the neuropathological findings and classification; progressive encephalopathies; and epilepsy. Neurologists will find the book invaluable.

  • Neurobiology and Behavior

    • 1st Edition
    • A. O. Dennis Willows
    • English
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 1, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in molluscs. The book contains four chapters and begins with a chapter on the behavior of gastropod mollusks. Subsequent chapters deal with learning in gastropod mollusks, the neuronal control of behavior in gastropods, and the development and plasticity of molluscan neurons.

  • The Study of Behavioral Development

    • 1st Edition
    • Joachim F. Wohlwill
    • David S. Palermo
    • English
    The Child Psychology Series: The Study of Behavioral Development concerns the formulation of general laws of development, transcending the realm of the development of the individual from infancy to maturity. This book provides a systematic treatment of problems of research design, strategy, and data analysis that relate specifically to the study of developmental changes in behavior. The topics discussed include developmental psychology in the 1970s, age variable in psychological research, and programmatic view of the task of developmental psychology. The problems of measurement and quantification in developmental psychology, correlational methods in the study of developmental change, and experimental manipulation of developmental change are also elaborated. This publication is recommended for psychologists, specialists, and students learning the nature of behavioral change.

  • Brain Receptor Methodologies

    Amino Acids. Peptides. Psychoactive Drugs
    • 1st Edition
    • Paul J. Marangos + 2 more
    • English
    Brain Receptor Methodologies: Part B Amino Acids. Peptides. Psychoactive Drugs is the second of the two-part first volume of the Neurobiological Research series, which provides a comprehensive view of various subdisciplines within neurobiology. The first volume (Parts A and B) deals with the area of neurotransmitter and neuromodulator receptors in brain; future volumes will cover the subdisciplines of neuroanatomy, neurophysiology, brain-specific macromolecules, neurochemistry, and behavioral neurobiology. It is hoped that the series will be of equal value for both basic as well as clinical scientists Part B continues from Part A with the remainder of Section II, specific receptor binding methodologies. Subsection II,B deals with receptors for amino acids and neuropeptides and covers areas including GABA, glycine, carnosine, opiates, bombesin, CCK, TRH, and substance P. Amino acids probably represent the majority of brain neurotransmitter substances, at least relative to the amines and acetylcholine, although with the exception of GABA, the amino acids remain relatively uncharacterized in brain. Their further study should receive high priority.

  • Neurocutaneous Diseases

    A Practical Approach
    • 1st Edition
    • Manuel Rodriguez Gomez
    • English
    Neurocutaneous Diseases is a systematic presentation limited to diseases that affect both of the nervous system and skin of humans. Neurologists and dermatologist will find knowledge of these diseases of real clinical value. Many of the diseases described in these pages do not affect the skin and nervous system simultaneously. Many of these diseases, mostly not well understood, may stimulate new lines of scientific inquiry, for understanding of a pathologic change in easily accessible dermal cells that promises to clarify a more recondite brain disease. This book is organized into five main parts. The chapters describe different types of diseases including those with autosomal dominant inheritance, those with autosomal recessive inheritance, those with x-linked inheritance, those with unknown or multiple inheritance and congenital and vascular anomalies. These diseases include neurofibromatosis, Cockayne's Syndrome, adrenoleukodystrophy... albinism and neurocutaneous melanosis. This book will be of interest to dermatologists and neurologists.

  • Variation in Chemical Composition of the Nervous System

    As Determined by Developmental and Genetic Factors
    • 1st Edition
    • G. B. Ansell
    • English
    Variation in Chemical Composition of the Nervous System: As Determined by Developmental and Genetic Factors documents the proceedings of the International Neurochemical Conference held in Oxford, 1965. The three years since the last neurochemical meeting have witnessed rapid progress in the whole field of biology, including the development of new concepts based on fresh experimental data and new technical tools. A great deal of concentrated effort have led to advances in the molecular aspects of biological processes ,which have perhaps had most to offer to the formation of new concepts of primary cellular events, especially the genetic mechanism, regulatory cell processes, and protein production. This volume contains 100 chapters that provide an overview of the state of knowledge on the genetic and developmental aspects of the central nervous system. Topics covered include the activity of a plasma logenase in the brain of the developing rat; genetic selection of rats differing in brain biochemistry; the effects of thyroid hormones on steroid deposition in developing chick brain; and developmental changes in the gamma globulins of bovine cerebrospinal fluid.

  • Methods in Neurosciences

    Electrophysiology and Microinjection
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 4: Electrophysiology and Microinjection is a collection of papers that deals with the electrically excitability feature of many cell types. This volume describes the characteristic features of some nervous tissue to conduct signals along cellular paths or ""wires."" The text presents such paths as a way stimuli are transferred in the nervous system. Section I reviews the recording methodologies such as those used in measuring noninactivating calcium current in smooth muscles cells or the two-suction electrode voltage-clamp recording. Section II deals in detail with voltage clamping and voltammetry; the text also explains the practical steps in using the current pump-assisted voltage clamp. One paper examines the X-ray microprobe analysis of voltage clamped single heart ventricular myocytes, while another paper explains in vivo voltammetry. Section III addresses electrophysiology and purification of specific receptors; one paper presents the results of an electrophysiological study of hormone secretion by single adenohypophyseal cells. Section IV describes special electrodes and equipment, while Section V deals with special preparations needed in culture preparation or in the study of pharmacology of excitatory amino acids on neurons found in the central nervous system. Chapter VI addresses data analysis and reduction such as digital filtering of bioelectric potentials in personal computers. This book will prove valuable for microbiologists, cellular scientists, microchemists, and academicians working in the fields of neuroscience.

  • Neurology for Nurses

    • 1st Edition
    • J Bickerton + 1 more
    • English
    Neurology for Nurses is an attempt to make neurology as clear as possible, using the nursing model. The first portion of this book provides a diagram of the planes of the body that considers the nervous system anatomically, which is referenced throughout the book. The different orientations and planes of the body include the anterior (ventral) surface, posterior (dorsal) surface, lateral, medial, sagittal (median) section, Coronal (frontal) section, and transverse. Other than detailed descriptions of the anatomy and functions of nerves and the nervous system, this book provides diagnostic evaluation of diseases and clinical conditions, such as multiple sclerosis, cerebrovascular accidents, brain tumors, head injury, epilepsy, Parkinson's disease, and meningitis. This book includes as well discussions on neurological examinations, investigations, and observations. The topic on nursing care for unconscious patients is also provided. This text is aimed primarily at nursing students in training, but will also benefits those taking a post-basic nursing course in neurology.

  • Principles, Practices, and Positions in Neuropsychiatric Research

    Proceedings of a Conference Held in June 1970 at the Walter Reed Army Institute of Research, Washington, D.C., in Tribute to Dr. David Mckenzie Rioch upon His Retirement as Director of the Neuropsychiatry Division of That Institute
    • 1st Edition
    • Joseph V. Brady + 1 more
    • English
    Principles, Practices and Positions in Neuropsychiatric Research contains the proceedings of a conference held in June 1970 at the Walter Reed Army Institute of Research, Washington, D.C., in tribute to Dr. David McKenzie Rioch upon his retirement as Director of the Neuropsychiatry Division of that institute. This book is composed of the original contributions presented at the conference, as well as several invited papers that could not be programmed at the meeting because of certain limitations. Topics covered in some papers focus on anatomy of the thalamus; glia-neuronal interaction; receptor characteristics and conduction velocities in bladder afferents; responses of photoreceptors; and specificity of responses of cells in the visual cortex. This text also discusses the channeling of responses elicited by hypothalamic stimulation; neurochemistry of reward and punishment; behavioral analysis of aphasia; and biology of sleep. The military psychiatry and changing systems of mental health care, as well as psychological issues in training for research in psychiatry are also addressed. The contributions in this book will serve to reflect the remarkable range of bio-social research interest and competence.

  • Intensive Care for Neurological Trauma and Disease

    • 1st Edition
    • Barth A. Green + 2 more
    • English
    Intensive Care for Neurological Trauma and Disease presents the progress in intensive care in terms of technological development on life-support and monitoring systems. This book discusses the ideal neurologic intensive care environment that is based on developments in other specialized care units. Organized into 24 chapters, this book begins with an overview of the problem of neurological trauma. This text then presents the accident scene management protocol for acute spinal cord injury as a standard to other forms of trauma system pre-hospital care. Other chapters consider the appropriate drugs and dosages for the management of status epilepticus in the newborn and older children. This book discusses as well the findings on the neurological examination and provides a framework for an etiological classification that has direct therapeutic implications. The final chapter deals with the clinical aspects, diagnosis, and management of neuromuscular diseases. This book is a valuable resource for clinicians and intensive care unit nurses.

  • Textbook of Neuropathology

    • 2nd Edition
    • Arthur Weil
    • English
    Textbook of Neuropathology, Second Edition covers some of the significant advances in understanding the theoretical and experimental aspects of neuropathology. Neuropathology is the study of the nervous tissue in disease and the determination of deviations of its structures from the normal. This edition is composed of 13 chapters, and begins with the description of the chemical changes occurring in the cell through autolysis and fixation. The subsequent chapters are devoted to studies on better understanding of the vitamin deficiencies, the discovery of the sulfonamides and their contribution to the therapy of meningitis, and the different forms of shock treatment applied to selected cases of neurosis and psychosis. The remaining chapters explore the contribution of neuropathological investigation in various medical conditions, including anemic softening, arteriosclerosis, inflammation, infections, intoxications, injuries, degenerative diseases, tumors, and congenital malformations. This book will be of use to neuropathologists and workers and researchers in the allied fields.

  • Contemporary Neurology

    • 1st Edition
    • M.J.G. Harrison
    • English
    Contemporary Neurology compiles a large series of papers on the commonest neurological problems. This book discusses the management of epilepsy, involuntary movements, nerve and muscle diseases, and multiple sclerosis. The areas on infections, cerebrovascular disease, trauma, intracranial pressure, and vertebral column are also elaborated. This text likewise describes medical procedures on how to do a lumbar and cisternal puncture. Other topics include headache in children, hyperventilation, dizziness, funny turns—neurological, dysarthria, facial pain, and nystagmus. The weakness of the legs, loss of memory, coma, brain death, complications of alcoholism, and stupor and akinetic mutism are also covered. This publication is valuable to clinicians and examination candidates preparing for the DPM, MRCP (UK) and Neurology/Psychiatry “Boards”.

  • A Neurological Study of Newborn Infants

    Clinics in Developmental Medicine, No. 28
    • 1st Edition
    • David J. Beintema
    • English
    A Neurological Study of Newborn Infants considers the consistencies and inconsistencies of neonatal neurological signs. The possibility of a relationship between pre- and perinatal complications of pregnancy and later cerebral dysfunction has led to an increasing interest in the early detection of these defects in the newborn infant. This book is divided into nine chapters, and begins with a presentation of standardized procedures to obtain reliable information from the neurological examination. The next chapters deal with the developmental course of neurological signs during the first days of life. The final chapters discuss the potential effects of obstetrical and postnatal conditions on the developmental course and the consistency of neurological signs throughout the neonatal period. This book is an invaluable source for developmental biologists, neurologists, pediatricians, and obstetricians.

  • Studies in Neurolinguistics

    • 1st Edition
    • Haiganoosh Whitaker + 1 more
    • English
    Studies in Neurolinguistics, Volume 3 presents detailed case histories, multi-subject experimental studies, literature reviews, and research papers that employ a variety of experimental and observational techniques. This volume contains seven chapters that focus on a wide range of research in the field of neurolinguistics. Chapter 1 discusses the various approaches to the problem of auditory comprehension in aphasia. A survey of the world's literature on bilingualism and aphasia is provided in chapter 2. The third chapter examines the different models and explanations for conduction aphasia. Chapter 4 provides a synthesis of the anatomic, physiologic, and behavioral research on the role of the limbic system in human communication. Chapter 5 presents a model of individual differences in hemispheric functioning, in which a number of theories about the left and right hemispheres are analyzed and compared. Chapter 6 shows how different levels of language are revealed. The last chapter addresses "The Question of Electrophysiological Asymmetries Preceding Speech" in a study of the readiness potentials over the motor and premotor regions in eight subjects. Linguists, psychologists, and neurologists will find the book highly informative.

  • Peripheral Neuropathies

    Proceedings of the International Symposium on Peripheral Neuropathies Held in Milan, Italy, on June 26–28, 1978
    • 1st Edition
    • N. Canal + 1 more
    • English
    Peripheral Neuropathies compiles lectures presented at the Symposium on Peripheral Neuropathies held in Milan, Italy on June 26-28, 1978. This book covers the basic problems in peripheral nerve pathology; axonal transport; neuropathies in chronic renal failure; peripheral neuropathies in diabetes; compression neuropathies; and metabolic, genetic, and inflammatory neuropathies. This text also discusses topics such as filamentous inclusions in Schwann cell nuclei; autonomie dysfunction and myokymia in gold neuropathy; study of the effect of gangliosides on experimental carbon disulfide neuropathy; and peripheral nerve changes in Refsum's disease before and after treatment. This compilation is a useful source of information for students and researchers conducting investigative work on peripheral neuropathy.

  • Minireviews of the Neurosciences from Life Sciences

    • 1st Edition
    • Bernard B. Brodie + 1 more
    • English
    Minireviews of the Neurosciences from Life Sciences is a collection of minireviews of research in the neurosciences and originally published by the Journal of Life Sciences. These minireviews cover a wide range of topics such as the function and organization of the chromaffin vesicle; taste receptor proteins; the role of cyclic nucleotides in visual excitation; and regulation of tryptophan and tyrosine hydroxylase. Comprised of 34 chapters, this volume begins with a discussion on Na,K-ATPase, followed by an analysis of the function and organization of the chromaffin vesicles of the adrenal medulla. Subsequent chapters focus on the nerve growth factor and the acetylcholine receptor; sympathetic regulation of thyroid hormone secretion; the role of cyclic AMP in the action of antidiuretic hormone on the kidney; and neurochemical correlates of synaptically active amino acids. The role of calcium in the central effects of biogenic amines is also examined, along with the brain mechanisms underlying motor control, molecular coding of memory, and opiate receptors. This book should be of value to teachers, researchers, and students.

  • Quantitative and Qualitative Microscopy

    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 3: Quantitative and Qualitative Microscopy is a collection of papers that deals with microscopic techniques in statistical measures. This volume describes microscopy using sophisticated stains and dyes to advance observation of tests and experiments. Section I describes autoradiography including micro chemical methods, high-resolution autoradiography, and single- or double-label quantitative autoradiography for use in imaging of brain activity patterns or determining cerebral physiology. Section II discusses the quantification of structures through statistical and computational methods including dynamic video imaging technology. Section III explains the use of tracers, toxins, or dyes in tracing neuronal connections. One paper addresses the use of small injections of axonally transported fluorescent tracers. Section IV explains staining technology such as using the silver impregnation method for frozen sections of human nervous tissue that are gathered from tissues preserved in formalin. Section V addresses freezing techniques and those using freeze-fracture methods in neurobiology. The text also discusses cryoprotection and other freezing methods to control ice crystals found in fixed or unfixed brain tissues. Section VI presents the combined and high-resolution methods in polarization microscopy and microscopic investigations. Cellular biologists, micro-chemists, and scientific researchers in the field of micro- and cellular biology will appreciate this book.

  • Models of Human Memory

    • 1st Edition
    • Donald A. Norman
    • English
    Models of Human Memory provides an overview of the state of knowledge on human memory models. The book begins with an introductory chapter on the basic stages of the memory system and the historical roots of memory models. The remaining chapters are organized into five parts. Part I on memory systems covers topics such as a system for perception and memory; multi-trace strength theory of memory; and a model for postperceptual verbal memory that postulates a single memory store, with multiple copies, called replicas, created in memory by rehearsal processes. Part II presents studies phoneme storage and word recognition. Part III on memory for associations examines the storage-retrieval theory for the memorizing processes and presents simple model of short-term memory (STM) for paired associates. Part IV on storage and retrieval mechanisms deals with mechanisms of repetition and rehearsal in short-term memory; models of recall and recognition; and memory search models. Part V presents a theory of human long-term associative memory; and examines conceptual and methodological interactions between information-processi... investigations of cognitive activity and attempts to build models of memory.

  • British Surgical Practice

    Abdominal Emergencies to Autonomic Nervous System
    • 1st Edition
    • Ernest Rock Carling + 1 more
    • English
    British Surgical Practice, Volume I describes the diagnosis, physiology, symptoms, treatment, and appropriate surgical procedure of various health problems. This book is composed of 45 chapters, and begins with discussions on the available treatment and surgical options for abdominal problems, abortion, formation of abscess, achlorhydria, acidosis, actinomycosis, and pulmonary tuberculosis. Other chapters describe the clinical features and surgical treatments for other medical conditions, including allergy, amebiasis, amputations, amyloidosis, angina pectoris, and angioma. Considerable chapters explore the fundamentals and principles of post-operative methods and surgical anesthesia. The concluding chapters consider the surgical options for anus problems, anxiety states, appendicitis, arthritis, and artery and autonomic nervous problems. Surgeons, physicians, and medical personnel will find this book invaluable.

  • Comparative Neuropathology

    • 1st Edition
    • J. R. M. Innes + 1 more
    • English
    Comparative Neuropathology focuses on documented accounts of neurologic diseases and congenital defects in animals. The book first offers information on neuropathology, neuroanatomy, and cerebrospinal fluid (CSF). The domesticated animals that have CSF include horses, dogs, pigs, cats, rabbits, and cattle. The text then elaborates on neurologic diseases of apes and monkeys. Discussions focus on confluent leucoencephalosis and perivascular myelosis, encephalopathies and dysenteric syndromes, meningitis, epilepsies, tuberculosis, cerebellar atrophy and experimental manganese poisoning, and choreic syndrome in baboons with corticostriate encephalitis. The publication examines the diseases of the skeletal muscle and hypophysis, including general reactions of muscles to injuries, congenital defects, muscular dystrophies, changes in muscle associated with specific diseases, and tumor. The manuscript also takes a look at inherited diseases and congenital anomalies, protozoan and bacterial infections, and demyelinating or myelinoclastic diseases. The text is a dependable reference for readers interested in comparative neuropathology.

  • Receptors

    Model Systems and Specific Receptors
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design. The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior. This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.

  • The Neostriatum

    Proceedings of a Workshop Sponsored by the European Brain and Behaviour Society, Denmark, 17-19 April 1978
    • 1st Edition
    • Ivan Divac + 1 more
    • English
    The Neostriatum presents the puzzles of the neostriatum from many different angles. This book presents significant findings concerning the structure and neurotransmitters of the neostriatum. Organized into four parts encompassing 20 chapters, this book begins with an overview of the basic organization of the neostriatum. This text then illustrates an impressive complexity of extrinsic and intrinsic neostriatum circuitry. Other chapters consider the view that the nervous system evolved as a hierarchy, so that non-cortical structures such as the corpus striatum retain their structure and function even when the latter is made subservient to more developed mechanisms of the cerebral cortex. This book discusses as well the behavioral roles of the neostriatum and reviews the behavioral data obtained with each of the major treatment and recording techniques. The final chapter deals with the important features of striatal functions. This book is a valuable resource for neuropsychopharmacol... neuropsychologists, neurophysiologists, psychologists, and scientists.

  • Excitation and Inhibition

    Synaptic Morphology
    • 1st Edition
    • Koji Uchizono
    • English
    Excitation and Inhibition: Synaptic Morphology proposes the S-F hypothesis that emphasizes the relationship between structure and function of synapses. This book begins with an introduction to the notion of inhibition in the physiology of the nervous system and history of “synapse”, followed by a discussion on the development of concept and morphological correlates of excitation and inhibition in relation to the S-F hypothesis. The mechanism of synaptic excitation and inhibition, physiological classification of neurons, and release mechanism of transmitters are also elaborated. This text describes the synaptic vesicles as a basis of transmitter, membrane recycle, transmission in the sympathetic ganglion, and transmitter substance. The criticism of S-F hypothesis, which deliberates the skeptical investigations of specialists regarding the simplicity and immaturity of the S-F hypothesis of synaptic morphology are provided at the end. This publication is beneficial to medical students and practitioners aiming to acquire knowledge of the physiology of synapses.

  • Biophysical Aspects of Cerebral Circulation

    • 1st Edition
    • Yu. E. Moskalenko + 2 more
    • English
    Biophysical Aspects of Cerebral Circulation provides a comprehensive review of the cerebral circulatory system. This book consists of four chapters. Chapter 1 is devoted to methodology attempts to explain the special features of a biophysical approach. The biophysical principles of the most commonly used modem methods such as the clearance method and rheoencephalography are described in detail. The second and third chapters examine all the biophysical aspects of the cerebral circulatory system as a functional unit and deal with some principles of its regulation. The results of systems analysis using mathematical modeling are presented in broad outline. Chapter 4 deals with processes related to the regional cerebral circulation. Such investigations focus mainly on the relationship between periodically fluctuating factors affecting limited areas of brain tissue. This text is beneficial to medical students and individuals researching on cerebral circulation.

  • Neuropeptide Technology

    Synthesis, Assay, Purification, and Processing
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 6: Neuropeptide Technology: Synthesis, Assay, Purification, and Processing describes procedures and tools of assay useful for the identification, purification, and quantification of neuropeptides and their receptors. This volume is divided into four sections— chemical synthesis and biosynthesis; measurement of neuropeptides; purification and characterization; and neuropeptide degrading and processing enzymes. In these sections, this book specifically discusses the synthesis of peptide substrates for protein kinase C; synthesis of glycosyl neuropeptides; and ultrastructural localization of peptides. The measurement of neurokinin B by radioimmunoassay; purification and characterization of neuroendocrine peptides from rat brain; and preparation of glia maturation factor ß are also elaborated. This text likewise covers the assays for arginine/lysine carboxypeptidases and enzymes that metabolize atrial natriuretic peptide. This publication is beneficial to neuroscientists and students researching on the synthesis, assay, purification, and processing of neuropeptides.

  • Clinical Methods of Neuro-Ophthalmologic Examination

    • 1st Edition
    • Alfred Kestenbaum
    • English
    Clinical Methods of Neuro-Ophthalmologic Examination presents the clinical methods of ophthalmologic examination that may be helpful in neurologic differential diagnosis. Neuro-ophthalmologic examination has developed in two directions: the more precise methods and the unrefined yet fairly exact methods, such as diagnostic measurement by means of a simple ruler. This book is based on lectures delivered by the author to neurologists and ophthalmologists. This book is composed of 13 chapters and begins with a presentation of anatomic details that are important for the understanding of the various signs and symptoms. The next chapters examine the development of simple perimetry into quantitative perimetry and angio-scotometry, as well as the pathology of the optic nerve. Considerable chapters are devoted to intensive discussions on group of diseases that affect in a parallel way the central nervous system and the eye, such as chiasmal and retrochiasmal lesions, nystagmus, symmetrical eye movement disturbance, palpebral fissure, hemicrania. The final chapter outlines a routine neuro-ophthalmologic... examination. This book is directed toward neurologists and ophthalmologists.

  • Agrammatism

    • 1st Edition
    • Mary-Louise Kean
    • English
    Agrammatism provides an overview of the state of knowledge on agrammatism, typically defined as a disorder of sentence production involving the selective omission of function words and some grammatical endings on words. The book opens with discussions of the diversity of the disorder. This is followed by separate chapters that address primarily questions of syntactic structure in agrammatism, from both linguistic and psycholinguistic perspectives. Within these two gross sections there is no consensus among the conclusions reached by the various authors. However, the position is taken that agrammatism is a disorder distinct from other aphasie disorders of sentence structure. This position is reconsidered in the final two chapters. Because of the intrinsically interdisciplinary character of research on agrammatism, it is hoped that the work presented in this volume will be of interest to linguists and psycholinguists working in areas outside the domain of aphasia, as well as to neurolinguists and neuropsychologists who are already involved in the study of language deficits.

  • Neuropeptide Technology

    Gene Expression and Neuropeptide Receptors
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 5: Neuropeptide Technology: Gene Expression and Neuropeptide Receptors discusses procedures and tools of assay useful for the identification, purification, and quantification of neuropeptides and their receptors. This volume is divided into two sections—neuropeptid... gene expression and neuropeptide receptors. In these sections, this book specifically discusses the assays for peptide products of somatostatin gene expression; molecular assays for rat thyrotropin-releasin... hormone gene; and structure, expression, and chromosomal localization of human gene. The gastrin-releasing peptide or mammalian bombesin; semiquantitative analysis of cellular somatostatin mRNA Levels; and atrial natriuretic factor receptor assays are also elaborated. This text likewise covers the receptors for opioid peptides in brain and autoradiography of somatostatin receptors in rat cerebellum. This publication is beneficial to neuroscientists and students intending to acquire knowledge of gene expression and neuropeptide receptors.

  • The Physiology of Synapses

    • 1st Edition
    • John Carew Eccles
    • English
    The Physiology of Synapses covers the considerable advances in understanding the complex physiology of synapses. This book is divided into 16 chapters that emphasize the mechanism of synaptic transmission. The first chapters describe the structural and physiological features of chemically transmitting synapses. The subsequent chapters deal with the excitatory postsynaptic responses to presynaptic impulse and the release of transmitter by presynaptic impulses. These topics are followed by discussions of the impulse generation by the excitatory postsynaptic potential; the postsynaptic electrical events produced by chemically transmitting inhibitory synapses; the ionic mechanism generating the inhibitory postsynaptic potential. The last chapters consider the mechanism of inhibitory transmitter substances, pathways responsible for postsynaptic inhibitory action, and the trophic and plastic properties of synapses. This book will prove useful to physiologists, neurologists, and researchers.

  • Cognitive Development

    The Child's Acquisition of Diagonality
    • 1st Edition
    • David R. Olson
    • David S. Palermo
    • English
    Cognitive Development: The Child's Acquisition of Diagonality is an empirical and rational enquiry into the child's development of a conceptual system relating to the concept of the diagonal during the age range three to six years. A detailed examination will be made of why a young child has difficulty with such a problem, and what occurs during development that removes this difficulty. In the context of these empirical arguments, the book considers such theoretical questions as the nature of intellectual skills and conceptual or symbolic knowledge, as well as the role of experience and instruction in their development. The study concludes with a description of the child's reconstruction of the diagonal in terms of what at least poses as a general model of perceptual and intellectual development, and accounts for, among other things, man's increasing ability to apprehend and theorize about the motion of the stars. It shows that it is the elaboration of the child's perceptual knowledge in the context of his performatory attempts in such cultural media as language and geometry that accounts for his ability to copy a diagonal in particular and his intellectual development in general.

  • Developmental Neuropsychobiology

    • 1st Edition
    • William T Greenough + 1 more
    • English
    Developmental Neuropsychobiology is a compendium of papers that deals with developmental neuroscience and developmental psychology, as well as the broad range of approaches toward brain-behavior development. One paper reviews the embryonic mechanisms including the pattern formation that develops in a single fertilized egg, particularly focusing on limb innervation as a special case of pattern formation. Another paper discusses the regulation of nerve fiber elongation during embryogenesis. One author analyzes the pathways and changing connections in the nervous system of the insect: he shows that manipulating neural organization by grafting results in the ability of the transplanted sensory cells to find the proper central connections. Another paper reviews the sex differences in developmental plasticity of behavior and the brain. These differences point to the vulnerability of males during development to incidences of autism, dyslexia, or cerebral palsy compared to females. One paper also examines alternative perceptions of parent- offspring relationships. This collection can prove helpful for researchers, students, and academicians involved in the disciplines of biological or psychological sciences.

  • Clinical Anesthesia in Neurosurgery

    • 1st Edition
    • Elizabeth A. M. Frost
    • English
    Clinical Anesthesia in Neurosurgery, Second Edition, integrates the evolution of the field of neuroanesthesia with the major areas of neurosurgical activity to give the reader the required perspective and requisite information to help in laying the foundation for future advances as well as describing the current state of the art. The book contains 25 chapters organized into five parts. Part I presents studies on cerebral physiology and evaluation. Topics covered include cerebral circulation and metabolism, intraoperative neurophysiologic monitoring, and central nervous system effects of anesthetic agents. Part II covers neurosurgical and related procedures, such as posterior cranial fossa surgery, surgery of the spine, and peripheral nerve surgery. Part III examines central nervous system trauma including spinal cord trauma and cardiovascular effects of severe head injury. Part IV takes up postoperative and intensive care, including postanesthetic care, neurosurgical intensive care, and parenteral nutrition while Part V deals with the medical criteria and legal aspects of brain death.

  • Progress in Behavior Modification

    Volume 4
    • 1st Edition
    • Michel Hersen + 2 more
    • English
    Progress in Behavior Modification, Volume 4, is a multidisciplinary serial publication that encompasses the contributions of psychology, psychiatry, social work, speech therapy, education, and rehabilitation. This serial aims to meet the need for a review publication that undertakes to present yearly in-depth evaluations that include a scholarly examination of theoretical underpinnings, a careful survey of research findings, and a comparative analysis of existing techniques and methodologies. The discussions center on a wide spectrum of child and adult disorders. The present volume opens with a chapter on behavioral treatment for obesity. This is followed by separate chapters on applications of reinforcement techniques in the areas of pollution control and energy conservation, job performance and unemployment, community self-government, racial integration, and others; and behavior modification in community settings. Subsequent chapters deal with demand characteristics in behavior modification; the clinical utility of biofeedback procedures; and the technology of training parents in behavior therapy. The final chapter reviews the rationale and empirical support for the extinction approach of implosive (flooding) therapy.

  • Neuroendocrine Perspectives

    Volume 3
    • 1st Edition
    • Eugenio E. Müller + 1 more
    • English
    Neuroendocrine Perspectives, Volume 3 provides information on amine and peptide biochemistry. This book discusses the availability of specific biochemical and histochemical techniques that have greatly advanced knowledge of central nervous system neurotransmitter and neuropeptide systems. Organized into nine chapters, this volume begins with an overview of the structure of corticotropin releasing hormone. This text then examines the possible role of the cerebrospinal fluid in the regulation of pituitary function. Other chapters consider the importance of cerebrospinal fluid as a route for the hypothalamic regulation of pituitary function. This book discusses as well the available information concerning the neuroendocrine mechanisms involved in the onset of female puberty in primate and subprimate species. The final chapter deals with pineal indole metabolism and its controlling mechanisms as well as information on the interactions of the pineal hormones with neuroendocrine-repro... axis. This book is a valuable resource for pharmacologists, research workers, and students.

  • Neuro-Ophthalmology

    • 1st Edition
    • R. Lindsay Rea
    • English
    Neuro-Ophthalmology provides information pertinent to the neuro-ophthalmologic... examination of the eye. This book discusses the anatomy and function of the eye as well as its various diseases. Organized into 17 chapters, this book begins with an overview of the various equipment and methods used in the examination of the eye, including the Snellen's test type, a 13 dioptre lens, and electric ophthalmoscope. This text then discusses the principal reactions of the normal pupil, including the direct light reflex, reflex to accommodation, the spino-pupillary reflex, the psychical reflex, the orbicularis reflex, and the oculo-sensory reflex. Other chapters consider the anatomy of the muscles and nerves of the eye as well as it adnexa. This book discusses as well the condition of optic atrophy and its various types. The final chapter deals with the distinction between headache and neuralgia. This book is a valuable resource for ophthalmic surgeons and ophthalmologists.

  • Progress in Neurology and Psychiatry

    An Annual Review
    • 1st Edition
    • E. A. Spiegel
    • English
    Progress in Neurology and Psychiatry: An Annual Review, Volume 22 covers the significant advances in the understanding of neurophysiology, neuro-ophthalmology, and psychiatry. This volume is organized into four sections encompassing 33 chapters that also deal with the neurological aspects of pain and motor disorders. The first part discusses the fundamentals of neuroanatomy, general and regional neurophysiology, neuropathology, and the pharmacological aspects of the central nervous system. The second part examines the diagnosis, symptoms, and clinical features of neurological disorders. This part also explores the anatomical aspects of neuro-ophthalmology, otoneurology, and pediatric neurology. The third part reviews the surgical treatments for various neuro-related problems, including trauma, brain tumors, pain, and motor disorders. The fourth part considers the application of clinical psychiatry to the diagnosis and treatment of mental and emotional disorders, both in children and adults. This book will prove useful to neurologists, clinicians, pediatricians, and psychiatrists.

  • Neuroendocrinology

    Volume II
    • 1st Edition
    • Luciano Martini + 1 more
    • English
    Neuroendocrinology, Volume II, is the second in a two-volume treatise designed to provide a survey of all aspects of the rapidly expanding science of neuroendocrinology. Only in recent years have the relations between the nervous system and the endocrine system come under intensive scrutiny, but their interactions have already been shown to be multiple and diverse. This diversity is reflected in the range of subjects covered. There are chapters on neural control of endocrine function; the effects of hormones on the brain; brain-endocrine interrelations during various phases of development; and the comparative aspects of neuroendocrine integration. The relation of brain chemistry to endocrine function, the effect of drugs on neuroendocrine mechanisms, and the new discipline of clinical neuroendocrinology have also been considered. Not only neurophysiologists and endocrinologists, but pharmacologists, zoologists, biochemists, psychologists, and those in clinical medicine will find the treatise of interest. Parts of neuroendocrinology have been discussed in other works, but this is the first treatise in which an attempt has been made to cover all ramifications of neuroendocrinology. This book can be used both as a text for advanced students and as a reference source.

  • Biochemical Factors Concerned in the Functional Activity of the Nervous System

    First International Meeting of the International Society for Neurochemistry, Strasbourg, 1967
    • 1st Edition
    • D. Richter
    • English
    Biochemical Factors Concerned in the Functional Activity of the Nervous System presents the biological aspects concerned in the functional activity of the nervous system. This book covers several interesting topics concerning the central nervous system, including phospholipids, RNA synthesis, nerve impulse flow, and nerve growth factor. Comprised of 213 chapters, this book begins with an overview of the electron micrographs of calcium–ATP–phosphol... complexes. This text then examines the biochemical and histochemical studies on sectioned rat spinal cords, which demonstrated two types of monoamine-reducing drugs. Other chapters consider the diversity of antagonistic relations between the thiamine derivatives and vitamin B6, which is manifested by changes in the glutamate–GABA, histidine–histamine, tryptophan–serotonin... and tyrosine–noradrenali... systems. This book discusses as well the influence of a conditioned avoidance training experience on the incorporation of radioactive uridine into the RNA of mouse brain. The final chapter deals with the amino acid-incorporating activity of cerebral polyribosomes. This book is a valuable resource for biochemists, neurologists, pharmacologists, and biophysicists.

  • Dale's Principle and Communication between Neurones

    Based on a Colloquium of the Neurochemical Group of the Biochemical Society, Held at Oxford University, July 1982
    • 1st Edition
    • Neville N. Osborne
    • English
    Dale's Principle and Communication Between Neurones is based on a colloquium of the Neurochemical Group of the Biochemical Society, held at Oxford University, July 1982. This book focuses on communication between neurones by means of chemical signals. The book contains an introductory chapter by V. P. Whittaker and nine further chapters on various aspects of the chemical communication processes between neurones. Topics covered include chemical communication between excitable cells; the neuroendocrine division of the nervous system; evidence for a neurone having the capacity to use two chemicals in the same process; and non-synaptic interneuronal communication. Each article is based on the excellent lectures given by the main authors and the discussion which ensued in the one-day colloquium held in Oxford. The final chapter is a specially invited contribution by Drs. Polak and Varndell, who agreed to produce an article on their new method of localising transmitter-like molecules at the electron-microscopic level.

  • The Release of Catecholamines from Adrenergic Neurons

    • 1st Edition
    • David M. Paton
    • English
    The Release of Catecholamines from Adrenergic Neurons covers the advances in understanding the mechanism of catecholamine release and other neurotransmitters from adrenergic neurons. This book is organized into four sections encompassing 18 chapters. The opening section surveys biochemical studies of the mechanism and regulation of nerve stimulation. This section examines the role of calcium, prostaglandins, and presynaptic adrenoceptors and muscarine receptors in catecholamine release. The next section describes the modification of catecholamine release by several drugs, including adrenergic neuron blocking agents, narcotic analgesics, opioid peptides, lysergic acid diethylamide, anesthetics, alcohols, and adenosine and adenine nucleotides. These topics are followed by discussions of catecholamine release induced by cations and other drugs, such as nicotinic agonists, calcium ionophores, veratridine, scorption venom, and phenethylamines. The final section deals with the biochemical assessment of peripheral adrenergic activity and the clinical pharmacology of adrenergic neuron blocking agents. This book is intended for pharmacologists, neurologists, researchers, and advanced students.

  • Neuropathology

    Brussels, 21-28 July 1957
    • 1st Edition
    • L. Van Bogaert + 1 more
    • English
    Neuropathology, Volume IV presents the proceedings of the First International Congress of Neurological Sciences, held in Brussels, Belgium, on July 21–28, 1957. This book provides information pertinent to the fundamental aspects of neuropathology. Organized into 84 chapters, this compilation of papers begins with an overview of the problem of multiple sclerosis and its relationship to leucodystrophies. This text then explains the two major histopathological manifestations of the injury caused by the rabies virus in the central nervous system. Other chapters consider the successful identification and isolation of a biologically active compound, which depends to a large extent on the availability of a quantitative bioassay. This book discusses as well the clinical manifestations, pathogenesis, and treatment of multiple sclerosis. The final chapter deals with the study of nucleic acids as well as histochemistry as a method of histological inquiry. This book is a valuable resource for neuropsychiatrists, biochemists, physicians, and scientists.

  • Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses

    Proceedings of a IUPHAR Satellite Symposium in Conjunction with the 8th International Congress of Pharmacology, Paris, France, July 27-29, 1981
    • 1st Edition
    • P. Lechat + 2 more
    • English
    Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses presents the proceedings of a IUPHAR Satellite Symposium in conjunction with the eighth International Congress of Pharmacology held in Paris, France on July 27-29, 1981. The book contains papers on the effects of aminopyridines on ionic currents in excitable membranes; the effects of aminopyridines on synaptic transmission; and the effects of aminopyridines on the release of chemical transmitters. The text also presents papers on some differences in the blockade of potassium permeabilities by apamin and the aminopyridines; the miscellaneous actions of aminopyridines and related compounds; and the effects of aminopyridines on the skeletal, smooth and cardiac muscle. The clinical applications of aminopyridines and further miscellaneous actions of aminopyridines and related compounds are also considered.

  • Case Presentations in Neurology

    • 1st Edition
    • G. S. Venables + 2 more
    • English
    Case Presentations in Neurology presents a selection of case histories demonstrating how patients with often quite simple problems may present and to bring out aspects of their diagnosis and management. All the patients presented to the Department of Neurology including those with more obscure diagnoses. The book consists of 12 exercises, each of six cases broadly corresponding to the style of the MRCP (UK) written case history papers. Each case is set out with the history and physical findings given first. There follows either a series of questions or true/false statements on one side of the page which the reader should attempt before continuing on to the answer section on the other side. There then follows a short discussion about each case and a single reference. This book is intended for those doctors studying for higher professional qualifications such as the MRCP, although it may be of interest and use to medical students approaching their final examinations.

  • Neurogenic Heart Lesions

    • 1st Edition
    • I. S. Zavodskaya + 2 more
    • English
    Neurogenic Heart Lesions reviews the main publications concerned with the problem of neurogenic lesions of the heart. The book describes the methods for producing experimental neurogenic lesions, as well as the pharmacological analysis of the participation of the sympathetic nervous system and its transmitters in the development of neurogenic lesions of the myocardium. The text also discusses the changes in energy metabolism and in functional conditions of the myocardium caused by neurogenic lesions; and the pharmacoprophylaxis and pharmacotherapy of the biochemical changes produced by neurogenic lesions of the myocardium. Pharmacologists, pathologists, and other clinicians and physicians concerned with the new achievements in the field of cardiology will find the book invaluable.

  • Steroid Hormone Regulation of the Brain

    Proceedings of an International Symposium Held at the Wenner-Gren Center, Stockholm, 27-28 October 1980
    • 1st Edition
    • Kjell Fuxe + 2 more
    • English
    Steroid Hormone Regulation of the Brain focuses on the advancement of knowledge of the properties of brain steroid receptors and steroid target nerve cells, including the actions of gonadal steroids, adrenocortical steroids, and androgenic steroids on the brain. The selection features the work of authors who have inspiringly conducted extensive studies on the action of steroid hormones. The book starts with discussions that point out that steroid hormones not only function through intracellular steroid receptors, but possibly through steroid membrane actions as well. Studies to support this claim are presented. As to the action of steroid hormones on presynaptic transmitter mechanisms, the book suggests that adrenocortical and gonadal steroids can create alterations in noradrenaline, adrenaline, and dopamine levels and turnover within the hypothalamus and preoptic area. The effects of catecholestrogens on the brain are also elaborated. A contribution to this paper stresses that estrogens have antidopaminergic action in the extrapyramidal system. This idea is identified through a series of behavioral experiments and measurements of the levels of striatal acetylcholine. This selection is recommended to scientists interested in studying the effect of hormones on the brain.

  • Neurobiology and Behavior

    • 1st Edition
    • A. O. Dennis Willows
    • English
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 2, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in mollusks. The book contains four chapters and begins with a discussion of neural control of cephalopod behavior. Subsequent chapters deal with the neuroanatomy of selected gastropod species; molluscan membranes, gates, and channels; and molluscan transmitters and modulators.

  • Aspects of Neural Ontogeny

    • 1st Edition
    • A. F. W. Hughes
    • English
    Aspects of Neural Ontogeny focuses on the interaction between the nervous system and peripheral organs during development, including history and development of neurons and the functions of nerves and muscles. The book first offers information on the development of neurons, including formation and growth of nerve fibers; growth cone and the extension of nerve fibers; history of the neuron theory; and path of nerve fibers. The manuscript then elaborates on the innervation of the tetrapod limb and the center and periphery. Discussions focus on the relationships between the ventral horn and muscles of the limb; experimental studies on limb plexus and limb nerves; and relationships between spinal nerves and limb muscles. The publication takes a look at the ontogeny of behavior, as well as pattern of motility, spontaneous movements, tetrapod limb, and experimental studies. The book is a dependable reference for readers interested in neural ontogeny.

  • Neurochemistry of the Retina

    Proceedings of the International Symposium on the Neurochemistry of the Retina Held in Athens, Greece, August 28 - September 1, 1979
    • 1st Edition
    • Nicolas G. Bazan + 1 more
    • English
    Neurochemistry of the Retina covers the proceedings of the International Symposium on the Neurochemistry of the Retina held in Athens, Greece, on August 28 – September 1, 1979. This book mainly focuses on the retina and its neurochemistry. This text is divided into eight major parts. The first part discusses the composition, metabolism, and biogenesis of membrane components. This book then explains the biochemical approaches to the study of visual cells and their relationship with the pigment epithelium, photorector shedding, and circadian rhythm. Chemical transmission of nerve signals is also tackled. This text also looks into the biochemical aspects of photoreceptor structure and function; cyclic nucleotides; and biochemical and pharmacological approaches to study the entire retina. This book concludes by explaining the neurochemical studies in retinal diseases and future research and prospective of the subject. This publication will be invaluable to ophthalmologists and students of ophthalmology.

  • Nervous System Theory

    An Introductory Study
    • 1st Edition
    • K. N. Leibovic
    • English
    Nervous System Theory: An Introductory Study focuses on the nervous system theory, stressing the means for understanding the nature of the biological system rather than the elaboration of mathematical theories. This book begins with a discussion on single-cell responses, followed by a discussion of sensory information processing that leads into models of perceptual processes and their possible neural bases. This text concludes with some general principles and theoretical investigations relating to units that make up a nervous system, through a sensory pathway and central structures. The peripheral stimuli that explain the operations of the brain are also described. This publication is a good reference for neurologists, medical practitioners, and researchers conducting work on the nervous system theory.

  • Computers and Computations in the Neurosciences

    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 10: Computers and Computations in the Neurosciences discusses the use of computers in the neurosciences. The book deals with data collection, analysis, and modeling, with emphasis on the use of computers. Section I involves data collection using a personal microcomputer system. One paper presents a tutorial on using a PC-based motor control composed of an electronic circuit to adjust the motion of a light microscope stage through a software program. Other papers discuss computer methods in nuclei cartography and a computer-assisted quantitative receptor autoradiography in studying receptor density distribution. Section II deals with data analysis and some computer programs for kinetic modeling of gene expression in neurons. The book also discusses a computerized analysis of opioid receptor heterogeneity by ligand binding in test animals using computerized programs instead of employing manual or graphical methods. Computerized curve-fitting allows the researcher to utilize a more precise mathematical model to describe the binding of one ligand to one class of sites. Section III evaluates data modeling and simulations and describes the practicality of using computers to design model ion channels. Another paper discusses a graphical interaction program called MEMPOT to simulate an electrophysiological investigation of the properties of the membrane potential in stimulated cells. The book also presents a quantitative data gathered from computer simulation of the factors that affect neuronal density per measured sections. The book is suitable for microbiologists, biochemists, neuroscientists, and researchers in the field of medical research, as well as for advanced computer programmers in medical research work.

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