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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Curcumin for Neurological and Psychiatric Disorders

    Neurochemical and Pharmacological Properties
    • 1st Edition
    • Tahira Farooqui + 1 more
    • English
    Curcumin for Neurological and Psychiatric Disorders: Neurochemical and Pharmacological Properties focuses on the different molecular mechanisms underlying curcumin-mediated beneficial effects in neurological diseases. The book's editors discuss the neurochemical and pharmacological properties of curcumin, followed by the effect of curcumin in neurotraumatic diseases, neurodegenerative diseases, and neuropsychiatric diseases. The book also offers a perspective on future studies on the treatment of neurological disorders. The beneficial effects of curcumin have been observed both in cultured cells and in animal models, thus paving the way for ongoing present and future human clinical trials. Curcumin produces antioxidant and anti-inflammatory effects not only by blocking oxidative stress and neuroinflammation in neurotraumatic and neurodegenerative diseases, but also by restoring cellular homeostasis and rebalancing redox equilibrium.

  • Central Serous Chorioretinopathy

    • 1st Edition
    • Jay Chhablani
    • English
    Central Serous Chorioretinopathy discusses the mechanisms, pathogenesis and risk factors of CSCR, findings on various imaging modalities, available treatment options, and translational research into new treatment options for CSCR management. This comprehensive book is written for retina specialists and surgeons, researchers and clinical practitioners in sensory systems (vision), and ophthalmologists. Central Serous Chorioretinopathy (CSCR) is a common disorder across the world with a variable prognosis without any standard of care. Recently, advancements in imaging have led to a better understanding of the pathogenesis and mechanisms of this disease.

  • Handbook of Sleep Disorders in Medical Conditions

    • 1st Edition
    • Josee Savard + 1 more
    • English
    Handbook of Sleep Disorders in Medical Conditions reviews the current knowledge on the nature and manifestations of sleep disorders associated with a variety of common medical conditions, including epilepsy, traumatic brain injury and dementia. It also provides clinical guidelines on how to assess and treat them with pharmacological and non-pharmacological interventions. Although the general principles of sleep medicine may be applied to some extent to patients with comorbid medical conditions, this book makes the case that an adaptive approach is warranted when considering the particularities of each condition. In addition, clinicians must also be cautious when prescribing sleep medications as some pharmacological agents are known to exacerbate symptoms associated with the medical condition, such as cognitive deficits (i.e. difficulties with memory and attention) in cancer patients experiencing chemo brain, or in persons with neurologic conditions (e.g. mild cognitive impairment, dementia, stroke, brain injury). A differential approach to evaluating and treating sleep is thus warranted.

  • Genes, Brain Function, and Behavior

    What Genes Do, How They Malfunction, and Ways to Repair Damage
    • 1st Edition
    • Douglas Wahlsten
    • English
    Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior.

  • Neural Stem Cells and Adult Neurogenesis

    • 1st Edition
    • Arie S. Mobley
    • English
    Neural Stem Cells and Adult Neurogenesis provides graduate students and neuroscientists with a basic understanding of what neural stem cells are and the cell types they produce. This early graduate level reference describes their physiology and potential for medicine and provides students with fundamental stem cell information. An overview of stem cell sources in the human body and a brief mention of relevant diseases provide context for the value of this knowledge. The book also includes chapters on induced pluripotent stem cells (iPSCs), the methods used to obtain them, and a review of the ethical challenges associated with stem cell research. For each region, the book provides a description of its neurogenic niche, cellular and molecular biology, and information on the neurons’ contribution to normal and diseased brain function. The level of information is appropriate for early graduate students, introducing technology and molecular biology in an accessible format.

  • Meditation

    • 1st Edition
    • Volume 244
    • English
    Meditation, Volume 244, the latest release in the Progress in Brain Research series, highlights new advances in the field with this new volume presenting interesting chapters on The effect of meditation on attentional processes, State-trait influences of Vipassana meditation practice on P3 EEG dynamics, What could teachers learn from the neuroscience of self-experience?, Training Attention for Conscious Non-REM Sleep: The Yogic Technique of Yoga Nidrā and Its Implications for Neuroscience Research, CNV and P3 modulations following sensorimotor training, Analytical meditation: a characterization of a reasoning-based meditation training, Buddhist meditation and the regulation of brain networks, Mindfulness-based Emotional Balance Training in Military Spouse, and more.

  • Role of Inflammation in Environmental Neurotoxicity

    • 1st Edition
    • Volume 3
    • English
    Role of Inflammation in Environmental Neurotoxicity, Volume Three, in this comprehensive serial, addresses contemporary advances in neurotoxicology by providing authoritative review articles on key issues in the field. Edited by leading subject experts, topics of note in this new release include Neuroinflammation (Introduction), Organophosphates, Lead, Manganese, Drugs of abuse, Peripheral vs central inflammation, Air pollution, Developmental neurotoxicity, Ethanol, and the Blood brain barrier, amongst other topics.

  • Cognitive Rehabilitation of Memory

    A Clinical-Neuropsychological Introduction
    • 1st Edition
    • Helmut Hildebrandt
    • English
    Cognitive Rehabilitation of Memory: A Clinical-Neuropsycho... Introduction comprehensively reviews evidence-based research for each clinical tool, defining guidelines on how to assess patients and set treatment goals and best practices for creating individualized rehabilitation programs. The book also provides essential background knowledge on the nature and causes of memory impairment. Dr. Helmut Hildebrandt describes a wide range of interventions, including memory aids, learning strategies and non-cognitive treatment options

  • Alzheimer’s Disease Theranostics

    • 1st Edition
    • Magisetty Obulesu
    • English
    Alzheimer’s Disease Theranostics discusses the latest information on recent theranostic avenues for both the diagnosis and treatment of Alzheimer’s patients. It presents the pros and cons of the probable mechanistic role of nanoparticles in crossing the blood-brain barrier and improving disease symptoms. Finally, it highlights the merits of existing maneuvers and suggests perspectives to aid in future developments. Despite the difficulty of drug delivery to the brain, there are some nanoparticulate platforms demonstrating promise in treating neurodegenerative disorders such as Alzheimer’s disease. Manifold theranostic maneuvers include antioxidants, natural bioactive compounds, gene therapy, and nanotechnological approaches, all of which are discussed in this important work.

  • Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder

    • 1st Edition
    • Volume 144
    • English
    Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder, Volume 144 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including chapters on Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional Magnetic Resonance Imaging of Dementia with Lewy Bodies, Network Imaging in Parkinsonian and Other Movement Disorders: Network Dysfunction and Clinical Correlates, Neuroimaging of Rapid Eye Movement Sleep Behavior Disorder, Hybrid PET-MRI Applications in Movement Disorders, and more.

  • Stress: Physiology, Biochemistry, and Pathology

    Handbook of Stress Series, Volume 3
    • 1st Edition
    • George Fink
    • English
    Approx.406 pages

  • Neuroblastoma

    Molecular Mechanisms and Therapeutic Interventions
    • 1st Edition
    • Swapan K. Ray
    • English
    Neuroblastoma: Molecular Mechanisms and Therapeutic Interventions comprehensively reviews current concepts in molecular and histopathological mechanisms that influence the growth of human malignant neuroblastoma, along with exciting therapeutic interventions. This book features a broad collection of contributions from leading investigators in histopathology, molecular mechanisms, genetics, epigenetics, microRNAs, proteomics, and metabolism in controlling growth and death in neuroblastoma. Recent developments in therapeutic interventions for neuroblastoma are also covered extensively, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy. This book is ideal for advanced undergraduate students, graduate students, medical students, postdoctoral fellows, and investigators with an interest in current molecular concepts and therapeutic interventions.

  • Neurobiology of Depression

    Road to Novel Therapeutics
    • 1st Edition
    • Joao L. de Quevedo + 2 more
    • English
    Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness.

  • The Auditory Brain and Age-Related Hearing Impairment

    • 1st Edition
    • Jos J. Eggermont
    • English
    The Auditory Brain and Age-Related Hearing Impairment provides an overview of the interaction between age-related hearing impairments and cognitive brain function. This monograph elucidates the techniques used in the connectome and other brain-network studies based on electrophysiological methods. Discussions of the manifestations of age-related hearing impairment, the causes of degradation of sound processing, compensatory changes in the human brain, and rehabilitation and intervention are included. There is currently a surge in content on aging and hearing loss, the benefits of hearing aids and implants, and the correlation between hearing loss, cognitive decline and early onset of dementia. Given the changing demographics, treatment of age-related hearing impairment need not just be bottom-up (i.e., by amplification and/or cochlear implantation), but also top-down by addressing the impact of the changing brain on communication. The role of age-related capacity for audio-visual integration and its role in assisting treatment have only recently been investigated, thus this area needs more attention.

  • The Orexin/Hypocretin System

    Functional Roles and Therapeutic Potential
    • 1st Edition
    • Jim R. Fadel + 1 more
    • English
    The Orexins/Hypocretins System: Functional Roles and Therapeutic Potential summarizes research on both the physiological functioning of orexins, their impact on homeostatic processes, and related disorders. The book encompasses the effects on appetite, sleep, substance abuse, cognition, and anxiety. Additionally, it examines new therapeutic approaches utilizing orexins, including utilization of orexin receptors for drug development. It is essential reading for neuroscience researchers interested in brain-behavior relationships, as well as psychiatrists, endocrinologists and pharmacologists.

  • Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain

    • 1st Edition
    • Michael Petrides
    • English
    Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain provides a comprehensive identification of the sulci and gyri of the human brain on a series of coronal sections of the average MNI brain and identifies the likely location of the cytoarchitectonic areas of the cerebral cortex. Presentation in MNI Stereotaxic Space enables the atlas to serve as a useful working tool for structural/functiona... neuroimagers attempting to identify the sulcus or gyrus and the likely cytoarchitectonic area within which a functional activation or a structural change has occurred. A brief introductory section discusses the history and current state of studies of the sulcal and gyral morphology and cytoarchitecture of the human cerebral cortex.

  • Imagining the Brain: Episodes in the History of Brain Research

    • 1st Edition
    • Volume 243
    • Chiara Ambrosio + 1 more
    • English
    Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • The Chick Brain in Stereotaxic Coordinates and Alternate Stains

    Featuring Neuromeric Divisions and Mammalian Homologies
    • 2nd Edition
    • Luis Puelles + 4 more
    • English
    This atlas – and its accompanying text - is the most comprehensive work on avian neuroanatomy available so far. It identifies more than 900 hundred structures (versus ca. 250 in previous avian atlases), 180 of them for the first time. It correlates avian and mammalian neuroanatomy on the basis of homologies and applies mammalian terms to homologous avian structures. This is the first atlas that represents the fundamental histogenetic domains of the vertebrate neuroaxis on the basis of sound fate-mapping and gene expression data. This results in a substantial increase in accuracy of delineations. Developmental molecular biologists will find it easier to extrapolate early neural tube patterns into mature structures. The modern trend to shift avian neuroanatomical nomenclature toward mammalian terminology by reference to postulated homologies has been expanded to the entire brain, but is not yet complete. This creates a new standard for comparative cross-reference, which can also be applied to reptilian-mammalian comparisons.

  • Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders

    • 1st Edition
    • Lindsay M. Oberman + 1 more
    • English
    Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders provides a comprehensive overview of neurotechnological devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents. Many neuropsychiatric disorders are covered such as Autism Spectrum Disorder, ADHD, Depression, Tourette’s Syndrome, and OCD. Different device-based treatments are discussed such as Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, Deep Brain Stimulation, Chronotherapy, and Neurofeedback.

  • Balance, Gait, and Falls

    • 1st Edition
    • Volume 159
    • English
    Balance, Gait, and Falls, Volume 159 presents the latest information on sensorimotor anatomy, sensory integration, gravity and verticality, standing balance, balance perturbations, voluntary stepping and gait initiation, gait and gait adaptability, disorders of balance and gait that result from aging and neurological diseases. The book provides a brief overview of age-related changes in the structure and function of sensorimotor and central processes, with sections specifically devoted to Parkinson’s disease, parkinsonism, cerebellar ataxia, stroke, corticobasal degeneration, multiple sclerosis, Huntington’s disease, dystonia, tremor, Alzheimer’s disease, frontotemporal dementia, cerebral palsy, polio, motor neuron disease, brainstem lesions, spinal lesions, peripheral nerve disease, and psychogenic conditions. Diseases covered have a common structure comprising background and epidemiology, pathology, balance disorders, gait disorders, falls, therapies (including fall prevention), and future directions.

  • Sports Neurology

    • 1st Edition
    • Volume 158
    • English
    Sports Neurology is designed to be a comprehensive overview of neurology within the context of sports medicine. This definitive text addresses the history of sports neurology, including its unique role within sports medicine, and provides a detailed assessment of central and peripheral nervous system injuries and illnesses in athletes. Sports Neurology is a critical companion for all sports medicine clinicians and for neurologists who manage athletes.

  • Neurosensory Disorders in Mild Traumatic Brain Injury

    • 1st Edition
    • Michael E. Hoffer + 1 more
    • English
    Mild traumatic Brain Injury (mTBI or Concussion) is an increasingly common public health issue in sports, military environments, and life in today’s active world. Despite a great deal of study and public attention to this disorder, knowledge about optimal diagnostic, prognostic, and treatment information remains lacking. Neurosensory symptoms have been shown to be the most frequent complications of mTBI in both the acute and chronic setting. Neurosensory Disorders in Mild Traumatic Brain Injury brings together both the basic science work as well as the clinical work in mTBI into one volume to provide a comprehensive examination of the neurosensory issues associated with this disorder. Coverage includes chapters on defining mild Traumatic Brain Injury, neurosensory consequences, neurosensory disorders in clinical practice, and diagnosis and treatment for neurosensory disorders in mTBI. This book is written for clinicians, researchers, residents and students in neurology and neuroscience.

  • Neurology of Pregnancy, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 37-1
    • Mary Angel O'Neal
    • English
    This issue of Neurologic Clinics, guest edited by Dr. Mary Angela O’Neal, with consulting editor Randolph W. Evans, will focus on Neurology of Pregnancy. Topics include, but are not limited to, Neuro-Ophthalmologic... Disorders in Pregnancy, Management of Demyelinating Disorders in Pregnancy, Postpartum Neuropathies, Management of Myasthenia Gravis during Pregnancy, Headache in Pregnancy and Postpartum, Epilepsy, Pituitary Disorders, Stroke, Imaging Considerations in Pregnancy, and Connective Tissue Disorders in Pregnancy.

  • Psychedelic Neuroscience

    • 1st Edition
    • Volume 242
    • Tanya Calvey
    • English
    We are in the midst of what is being called the ‘psychedelic renaissance’ with growing interest into how psychedelics alter consciousness, brain function and brain connectivity. The acute, often profound, effects of the psychedelic experience can induce lasting improvements in mental health demonstrating that chemistry forms the basis of mystical experience, consciousness and mental wellbeing.

  • Neuroergonomics

    The Brain at Work and in Everyday Life
    • 1st Edition
    • Hasan Ayaz + 1 more
    • English
    Neuroergonomics: The Brain at Work and in Everyday Life details the methodologies that are useful for keeping an ideal human-machine system up-to-date, along with information on how to prevent potential overload and minimize errors. It discusses neural measures and the proper methods and technologies to maximize performance, thus providing a resource for neuroscientists who want to learn more about the technologies and real-time tools that can help them assess cognitive and motivational states of human operators and close the loop for advanced human-machine interaction. With the advent of new and improved tools that allow monitoring of brain activity in the field and better identification of neurophysiological markers that can index impending overload or fatigue, this book is a timely resource on the topic.

  • Imaging in Movement Disorders: Imaging Applications in Non-Parkinsonian and Other Movement Disorders

    • 1st Edition
    • Volume 143
    • Marios Politis
    • English
    Imaging in Movement Disorders: Imaging in Other Movement Disorders and Dementia, Volume 143 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including idiopathic and sporadic forms of Parkinson’s disease, Huntington’s disease, Atypical Parkinsonism, Dystonia, Essential Tremor, and more. Specific chapters cover Neuroimaging Applications in Dystonia, Neuroimaging Applications in Essential Tremor, Neuroimaging applications in Restless Leg Syndrome, Neuroimaging Application in Tourette's Syndrome and TIC Disorders, Neuroimaging Applications in Functional Movement Disorders, and Neuroimaging Applications in Cerebellar Disorders. Addition sections cover Molecular Imaging of Parkinson's Disease Cognitive Impairment, Structural MRI in Parkinson's Disease Cognitive Impairment, Functional MRI in Parkinson's Disease Cognitive Impairment, Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional MRI of Dementia with Lewy Bodies, Transcranial Sonography in Movement Disorders, Imaging transplantation in Movement Disorders, Hybrid PET-MRI Applications in Movement Disorders, amongst other topics.

  • Thermoregulation Part II

    From Basic Neuroscience to Clinical Neurology
    • 1st Edition
    • Volume 157
    • English
    Thermoregulation, Part II: From Basic Neuroscience to Clinical Neurology, Volume 155, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions.

  • Handbook of Object Novelty Recognition

    • 1st Edition
    • Volume 27
    • English
    Handbook of Object Novelty Recognition, Volume 26, synthesizes the empirical and theoretical advances in the field of object recognition and memory that have occurred since the development of the spontaneous object recognition task. The book is divided into four sections, covering vision and perception of object features and attributions, definitions of concepts that are associated with object recognition, the influence of brain lesions and drugs on various memory functions and processes, and models of neuropsychiatric disorders based on spontaneous object recognition tasks. A final section covers genetic and developmental studies and gender and hormone studies.

  • The Molecular and Clinical Pathology of Neurodegenerative Disease

    • 1st Edition
    • Patrick A. Lewis + 1 more
    • English
    The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a unique perspective in relating clinical experiences with the molecular understanding needed to examine these diseases and is a must-read for anyone who wants to learn more about neurodegeneration.

  • Thermoregulation Part I

    From Basic Neuroscience to Clinical Neurology
    • 1st Edition
    • Volume 156
    • English
    Thermoregulation, Part I: From Basic Neuroscience to Clinical Neurology, Volume 154, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions.

  • Neurosurgical Neuropsychology

    The Practical Application of Neuropsychology in the Neurosurgical Practice
    • 1st Edition
    • Caleb M. Pearson + 2 more
    • English
    Neurosurgical Neuropsychology: The Practical Application of Neuropsychology in the Neurosurgical Practice comprehensively explains the use of neuropsychology in neurosurgical settings. The book covers various preoperative techniques that may benefit neurosurgeons, such as functional neuroimaging (fMRI, SPECT, MEG) for presurgical cognitive mapping, as well as more traditional methods to predict outcomes after surgery, including neurocognitive testing and the Wada procedure. The book's editors discuss why neuropsychologists add considerable value to the neurosurgical team. A wide range of patient populations are covered, ranging from Deep Brain Stimulation candidates for Parkinson’s disease, to adult and pediatric epilepsy candidates and neuro-oncology cases. This book is ideal for neurosurgeons, neuropsychologists, neuro-oncologists, epileptologists, general neurologists, and others who want to know more about the use of neuropsychology as a tool in the presurgical and postoperative phases of neurosurgery.

  • Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders

    • 1st Edition
    • Volume 241
    • English
    Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders, Volume 241 provides the most recent information on the animal model systems that are available to study different forms of autism spectrum disorders. In addition to genetically engineered animals that uniquely model genetic forms of ASD, this volume also provides detailed chapters on a variety of specific topics, including An overview of genetic models of ASDs, Phenotypic modeling of ASD symptoms, Molecular mechanisms of NF1 model of ASD symptoms, Ube3a gene dosage disorders: molecular and circuit mechanisms of ASD, Circuit dysfunctions in ASD models, ERK signaling in genetic models of ASD, and more.

  • Introduction to Electrophysiological Methods and Instrumentation

    • 2nd Edition
    • Franklin Bretschneider + 1 more
    • English
    Introduction to Electrophysiological Methods and Instrumentation, Second Edition covers all topics of interest to electrophysiologists... neuroscientists and neurophysiologists, from the reliable penetration of cells and the behavior and function of the equipment, to the mathematical tools available for analyzing data. It discusses the pros and cons of techniques and methods used in electrophysiology and how to avoid pitfalls. Although the basics of electrophysiological techniques remain the principal purpose of this second edition, it now integrates several current developments, including, amongst others, automated recording for high throughput screening and multimodal recordings to correlate electrical activity with other physiological parameters collected by optical means. This book provides the electrophysiologist with the tools needed to understand his or her equipment and how to acquire and analyze low-voltage biological signals.

  • Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders

    • 1st Edition
    • Volume 142
    • English
    Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders, Volume 142, addresses the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools have played a pivotal role in expanding our understanding of disease aetiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis and in the identification of novel targets for therapeutic intervention. This updated volume covers PET Molecular Imaging in Atypical Parkinsonism, SPECT Molecular Imaging in Atypical Parkinsonism, Structural MRI in Atypical Parkinsonism, Functional MRI in Atypical Parkinsonism, and more.

  • Simulation in Acute Neurology

    • 1st Edition
    • Sara E. Hocker + 1 more
    • English
    Simulation in Acute Neurology is a textbook on the execution of a simulation-based educational program in the management of acute neurologic emergencies. Simulation in Acute Neurology has practical value because it contains detailed descriptions of our simulation scenarios. The foundation of this book is our experience with neurosimulation―and it has been a very good one. Part I provides an overview of the principles of simulation in medicine and examines the many unique opportunities simulation provides as an educational tool. Barriers to simulating neurologic emergencies are also discussed. Simulation allows a physician-in-trainin... to be observed directly as he or she evaluates and manages acute neurologic disease. Part II is the core of the book. Fifteen acute neurologic emergencies, including complex neuroethical quandaries, are presented in detail, step by step, decision by decision, error after error. Each chapter in this section starts with an explanation of the essence of the discussed neuroemergency (THE PROBLEM BEFORE US), followed by a description of the scenario itself (THE PRESENTING CLINICAL PROBLEM), how scenarios can be adjusted to different types of learners (ADAPTING THE SCENARIO), and ends with a discussion of topics for feedback, which are generally focused around errors and pitfalls (DEBRIEFING). To show the flow of scenarios, we created two additional main headings: (THE IDEAL LEARNER) and (THE NOT-SO IDEAL LEARNER).

  • Imaging in Movement Disorders

    Imaging Methodology and Applications in Parkinson's Disease
    • 1st Edition
    • Volume 141
    • English
    Imaging Methodology and Applications in Parkinson's Disease, Volume 141, provides an up-to-date and comprehensive textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools has played a pivotal role in expanding our understanding of disease etiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis, and in the identification of novel targets for therapeutic intervention. This book brings together lessons learned from neuroimaging tools in movement disorders, including chapters on Advances in PET Methodology, Advances in MRI Methodology, Advances in SPECT Methodology, Hybrid PET/MRI Methodology, and more.

  • The Opioid System as the Interface between the Brain’s Cognitive and Motivational Systems

    • 1st Edition
    • Volume 239
    • English
    The Opioid System as the Brain’s Interface between Cognition and Motivation, Volume 239, focuses on the opioid system as the interface between the brain’s cognitive and motivational systems. As the opioid system is widely distributed through the brain, particularly in areas implicated in cognition (hippocampus, prefrontal cortex, claustrum, thalamus) and motivation (hypothalamus, amygdala, pontine nuclei, periaqueductal gray and medulla), this book provides chapters that address ongoing research on topics such as the Brain’s cognitive system, the Brain’s motivational system, Antidepressant prescription patterns, Antidepressant-like effects of opioid receptor modulators, the Behavioral effects of antidepressant and anxiolytic drugs, and more.

  • ADHD Complex

    Practicing Mental Health in Primary Care
    • 1st Edition
    • Harlan Gephart
    • English
    ADHD Complex: Practicing Mental Health in Primary Care, written by Dr. Harlan Gephart, provides a comprehensive review of key subjects of importance for primary care and family practitioners to help them better assess, diagnose, treat, and manage patient populations with ADHD. Dr. Gephart, Emeritus Clinical Professor of Pediatrics at University of Washington, has used his many years of experience and practice with this patient population to put together this helpful guide.

  • Pain Neuroethics and Bioethics

    • 1st Edition
    • Volume 1
    • English
    The treatment of pain and scientific pursuits to understand the mechanisms underlying pain raise many ethical, legal, and social issues.　For the first time, this edited volume brings together content experts in the fields of pain, pediatrics, neuroscience, brain imaging, bioethics, health humanities, and the law to provide insight into the timely topic of pain neuroethics. This landmark volume of the state of the art exploration of pain neuroethics will be a must read for those interested in the ethical issues in pain research, treatment, and management.

  • Brain Targeted Drug Delivery Systems

    A Focus on Nanotechnology and Nanoparticulates
    • 1st Edition
    • Huile Gao + 1 more
    • English
    Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain.

  • Animal Models for Examining Social Influences on Drug Addiction

    • 1st Edition
    • Volume 140
    • English
    Animal Models for Examining Social Influences on Drug Addiction, Volume 140 in the International Review of Neurobiology series, provides insights on social factors that mediate drug addiction. This book discusses current research and projects, with specific chapters focusing on Social Influences on Nicotine-related Behaviors in Rodents, Models of Alcohol Intake in Social Contexts, Social Factors in Ethanol Sensitization, Social Modulation of Heroin Intake, Amphetamines and Social Aspects of Addiction, Amphetamines and Social Aspects of Addiction, Social Models of Cannabis Use, Oxytocin and Rodent Models of Addiction, Social Place Preference and Reward, Social Defeat Stress, and more.

  • Handbook of in Vivo Neural Plasticity Techniques

    A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition
    • 1st Edition
    • Volume 28
    • English
    Handbook of in Vivo Neural Plasticity Techniques, Volume 28: A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition gives a comprehensive overview of the current methods and approaches that are used to study neural plasticity from a systems neuroscience perspective. In addition, the book offers in-depth methodological advice that provides the necessary foundation for researchers establishing methods and students who need to understand the theoretical and methodological bases of these approaches. This is the ideal resource for anyone new to the study of cognitive and behavioral neuroscience who seeks an introduction to state-of-the-art techniques.

  • Neural Mechanisms of Addiction

    • 1st Edition
    • Mary Torregrossa
    • English
    Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research.

  • Neurobiology of the Placebo Effect Part II

    • 1st Edition
    • Volume 139
    • English
    Neurobiology of the Placebo Effect, Part II, Volume 139, the latest release in the International Review of Neurobiology series, is the second part of a two-volume set that provides the latest placebo studies in clinically relevant models. Specific chapters cover the History of placebo effects in medicine, Lumping or Splitting: Towards a taxonomy of placebo and related effects, Theories and brain mechanisms of placebo analgesia, Pain Modulation: From CPM to placebo and nocebo effects in experimental and clinical pain, Modulation of the motor system by placebo and nocebo effects, and the role of sleep in learning placebo effects, amongst other topics.

  • Goal-Directed Decision Making

    Computations and Neural Circuits
    • 1st Edition
    • Richard W. Morris + 2 more
    • English
    Goal-Directed Decision Making: Computations and Neural Circuits examines the role of goal-directed choice. It begins with an examination of the computations performed by associated circuits, but then moves on to in-depth examinations on how goal-directed learning interacts with other forms of choice and response selection. This is the only book that embraces the multidisciplinary nature of this area of decision-making, integrating our knowledge of goal-directed decision-making from basic, computational, clinical, and ethology research into a single resource that is invaluable for neuroscientists, psychologists and computer scientists alike. The book presents discussions on the broader field of decision-making and how it has expanded to incorporate ideas related to flexible behaviors, such as cognitive control, economic choice, and Bayesian inference, as well as the influences that motivation, context and cues have on behavior and decision-making.

  • Gunner Goggles Neurology

    • 1st Edition
    • Hao-Hua Wu + 1 more
    • English
    The Gunner Goggles Series is the first exam prep resource written by a high-scoring peer group of medical students, ensuring the most practical and efficient study guidance. It organizes topics around the USMLE and NBME content outlines for the required shelf exams and features state-of-the-art Augmented Reality (AR) mobile application to extend learning beyond the book. This innovative series features AR opportunities throughout the text for an integrated print-mobile experience that maximizes learning and test preparation. The Gunner Goggle function allows you to scan pages for integrated AR links, unlocking animations, visuals, and 3D models that clarify complex anatomy, conditions, and concepts in a remarkably effective and unique manner. Gunner Goggles Series: Neurology is one of seven authoritative exam preparation guides that use cutting-edge AR technology to fully prepare you for the NBME clinical shelf exams, the USMLE Step 2 Clinical Knowledge (CK) exam, and successful clinical rotations.

  • Cerebral Lateralization and Cognition: Evolutionary and Developmental Investigations of Behavioral Biases

    • 1st Edition
    • Volume 238
    • English
    Cerebral Lateralization and Cognition: Evolutionary and Developmental Investigations of Motor Biases, Volume 238, the latest release in the Progress in Brain Research series, discusses interdisciplinary research on the influence of cerebral lateralization on cognition within an evolutionary framework. Chapters of note in this release include Evolutionary Perspectives: Visual/Motor Biases and Cognition, Manual laterality and cognition through evolution: An archeological perspective, Laterality in insects, Motor asymmetries in fish, amphibians and reptiles, Visual biases and social cognition in animals, Mother and offspring lateralized social interaction across animal species, Manual bias, personality and cognition in common marmosets and other primates, and more.

  • Neuro-oncology, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 36-3
    • Patrick Y Wen + 1 more
    • English
    This issue of Neurologic Clinics, edited by Drs. Patrick Y. Wen and Eudocia Quant Lee, will focus on Neuro-oncology. Topiocs include, but are not limited to, Epidemiology of brain tumors, Molecular pathogenesis of brain tumors, Changes in WHO classification of brain tumors, Neurologic and medical management of brain tumors, Grade 2 and 3 Gliomas, Glioblastoma, Benign brain tumors, Primary CNS lymphoma and neurologic complications of systemic lymphoma, Pediatric brain tumors, Brain metastases, Metastatic complications of cancer, Neurologic complications of radiation therapy, Neurologic complications of systemic anticancer therapies, Neurocognitive complaints in cancer patients, and Paraneoplastic syndromes.

  • Neuroinflammation

    • 2nd Edition
    • Alireza Minagar
    • English
    Neuroinflammation, Second Edition, discusses the role inflammation plays in neuro-inflammatory diseases. As research in neuroinflammation has dramatically increased in recent years, this new edition covers all of the new developments and findings since the first publication nearly a decade ago. Comprehensive coverage of topics includes chapters on multiple sclerosis, optic neuritis and Susac syndrome. New chapters cover the latest research in Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury, amongst other topics. Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma and meningitis, and it contributes to the generation of pain. Researchers are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage, through tolerance, and to modulation and repair.

  • Emergent Neuroimaging: A Patient Focused Approach, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 28-3
    • Diego B. Nunez
    • English
    This issue of Neuroimaging Clinics of North America focuses on Emergent Neuroimaging: A Patient Focused Approach, and is edited by Dr. Diego B. Nunez. Articles will include: The adult patient with acute neurologic deficit: an update on imaging trends; The patient with thunderclap headache; Imaging considerations in the patient with intracerebral hemorrhage; Emergent neuroimaging in the oncologic and immunosuppressed patient; Emergent neuroimaging during pregnancy and puerperium; Imaging the unconscious “found down” patient in the ED; Neurological emergencies in the pediatric patient including accidental and non-accidental trauma; Head and neck injuries: special considerations in the elderly patient; Current challenges in the use of CT and MRI in suspected cervical spine trauma; Radiation considerations in emergent neuroimaging; Blunt cranio-cervical trauma: Does the patient have a cerebral vascular injury?; New and emerging patient-centered CT imaging and image-guided treatment paradigms for maxillofacial trauma; Acute neurological syndromes beyond stroke: The role of emergent MRI; and more!

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