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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • The Brain Histaminergic System in Health and Disease

    • 1st Edition
    • Zhong Chen + 2 more
    • English
    Histamines in Neurology and Psychiatry summarizes histamines and their impact on neuroinflammation and brain development in key neural circuits. This book presents the latest research on the physiological regulation of a neuroendocrine responses and releases, broadly discussing histamine receptor modulators and histamine effects in neurology and psychiatry, and also including clinical applications that will be of interest to practitioners.

  • The Zebrafish Model of Neurodegenerative Disorders

    Knowing the Unknown
    • 1st Edition
    • Wael Mohamed
    • English
    The Zebrafish Model of Neurodegenerative Disorders: Knowing the Unknown reveals a ground-breaking method for decoding neurodegenerative disorders such as Parkinson's, Alzheimer's, ALS, and Huntington's through the lens of the zebrafish. This volume bridges the divide between fundamental science and clinical innovation, demonstrating how the genetic malleability, transparent embryos, and conserved neural pathways of zebrafish provide unparalleled insights into neurodegeneration. It illustrates the potential to uncover concealed pathological mechanisms, expedite drug discovery, and surmount the translational failings that impede current research using this gold-standard model species. Featuring contributions from global experts, this volume is systematically structured into five topical sections for ease of navigation. These sections explore the role of cutting-edge tools such as CRISPR-Cas9, AI-driven phenotyping, and high-throughput drug screening in the study of α-synuclein aggregation in Parkinson's Disease and amyloid-β toxicity in Alzheimer's Disease. The volume offers real-world applications, comparative analyses of zebrafish and mammalian models, and actionable protocols that translate zebrafish discoveries to clinical trials. The Zebrafish Model of Neurodegenerative Disorders is designed to empower researchers, clinicians, and healthcare professionals by addressing existing gaps in knowledge, particularly fragmentation in protocols and the translational disconnect between preclinical models and human trials. By fostering an integrated understanding of zebrafish as a model for neurodegeneration, it enhances research reproducibility, accelerates drug discovery, and promotes ethical, scalable research practices. Whether used as a teaching resource or a reference for experimental design, this volume offers invaluable insights to advance the understanding and treatment of devastating neurodegenerative diseases.

  • Blood-Based Biomarkers for Alzheimer's and Parkinson's Disease – Part B

    • 1st Edition
    • Volume 193
    • English
    Blood-Based Biomarkers for Alzheimer's and Parkinson's Disease – Part B, published as Volume 193 of the serial International Review of Neurobiology, provides a comprehensive examination of emerging blood-based biomarkers and related biological mechanisms relevant to Alzheimer's disease, Parkinson's disease, vascular cognitive impairment, stroke, and other neuropsychiatric disorders. The volume highlights advances in biomarker discovery, genetic and epigenetic determinants of neurodegeneration, extracellular vesicles and exosomes, protein misfolding, microRNA dysregulation, blood-brain barrier dysfunction, and biofluid-based biosensing technologies. It also explores the integration of artificial intelligence with multimodal biomarker datasets to improve diagnosis, prognosis, and precision medicine approaches. Bringing together contributions from international experts, this volume offers researchers and clinicians an up-to-date resource on translational developments that are shaping the future of neurodegenerative disease detection and management.

  • Adult Hydrocephalus and Disorders of CSF Dynamics

    • 1st Edition
    • Benjamin D. Elder + 1 more
    • English
    Adult Hydrocephalus and Disorders of CSF Dynamics reviews the pathophysiology, evaluation, differential diagnosis, management and treatment of adult hydrocephalus and disorders of cerebrospinal fluid (CSF). The introductory section begins with the anatomy and physiology of the cerebrospinal fluid system, with a review of adult hydrocephalus management, including longitudinal care and management of comorbidities. The following technical section devoted to shunt design and development, and then management of patients with idiopathic normal pressure hydrocephalus (iNPH). Coverage includes differential diagnosis and treatment of iNPH, as well as common presentations, neuroimaging, genetic studies, CSF biomarkers, and using artificial intelligence. Confirmatory testing discusses high volume lumbar punctures, lumbar drainage trials, and CSF infusion testing. Medical and surgical treatments are reviewed with expected functional outcomes. A subsequent section discusses secondary normal pressure hydrocephalus, caused by other etiologies such as hemorrhage, tumors, or infection, and covers longstanding overt ventriculomegaly (LOVA), management of adult patients who were shunted as children, and Chiari malformations. The book concludes with high and low pressure CSF dynamics disorders, including idiopathic intracranial hypertension and secondary intracranial hypertension, followed by a review of the medical, surgical, and ophthalmological management of these disorders.

  • Roles of the Cerebellum in Motor Control

    Foundations, Experimental Approaches and Clinical Applications
    • 1st Edition
    • Mario Manto + 2 more
    • English
    Roles of the Cerebellum in Motor Control: Foundations, Experimental Approaches and Clinical Applications is a groundbreaking, comprehensive reference on the intricate relationship between the cerebellum and motor function. Spanning five thorough sections, this book examines experimental approaches, from single neurons to networks, unraveling the mysteries of olivocerebellar somatotopy, motor prediction, and the cellular basis of motor learning. With chapters dedicated to neuroimaging, physiology, and pathophysiology, users will gain insight into the cerebellum's role in conditions such as tremor, dystonia, and Parkinson’s disease.From wearable sensors to digital gait biomarkers, various chapters offer a cutting-edge look at sensor technology and its application in assessing cerebellar function and rehabilitation. The book concludes with a discussion on research and clinical implications, providing a roadmap for translating laboratory findings into effective therapeutic strategies, making it an indispensable resource for researchers, clinicians, and students alike.

  • Sleep Neurology

    • 1st Edition
    • Anne Marie Morse
    • English
    Sleep Neurology explores the intricate relationship between sleep and neurological health, bridging the gap between theoretical knowledge and practical application. This comprehensive reference highlights the role of sleep in overall health and provides an examination of how sleep influences a wide range of neurological disorders. From neurodevelopmental issues to neurodegenerative diseases, this book offers a detailed review of how sleep science can be applied to improve patient outcomes in various neurological conditions. Structured around key neurological topics, the book offers insights into conditions such as epilepsy, stroke, and traumatic brain injury, emphasizing the importance of sleep management in their treatment. Each chapter not only discusses the scientific underpinnings of sleep but also provides tangible strategies for integrating sleep health into primary neurological care.

  • Endoscopic Transoral Surgical Approaches to the Skull Base

    • 1st Edition
    • Nyall London + 2 more
    • English
    Endoscopic Transoral Surgical Approaches to the Skull Base provides the first reference for endoscopic transoral surgical techniques and to improve education and training in endoscopic transoral skull base surgery. These approaches can be challenging; this book solves the problem by providing a collection of information regarding these surgical approaches and a dissection guide. This volume will act as a cadaveric surgical dissection guide to assist those interested in utilizing these surgical techniques

  • Reasoning

    An Integrative Approach
    • 2nd Edition
    • Daniel Krawczyk
    • English
    Reasoning: An Integrative Approach, Second Edition provides an overview, summary, and synthesis of research approaches to the psychology of reasoning. Representing historical perspectives, state-of-the art research, and coverage of upcoming future directions, this volume offers an integrative approach including research on animal behavior, neuroscience, cognitive psychology, AI, development, medicine, and philosophy. The contents range from animal studies through applied situations, and present historical perspectives, discussion of both animal reasoning and human reasoning to provide a cross-species context, and an examination of human reasoning across the lifespan. Though intended primarily for neuroscientists, the book will provide an interdisciplinary examination of reasoning, synthesizing perspectives from neuroscience, cognitive psychology, animal behavior, development, and philosophy, to provide readers with a well-rounded understanding of what reasoning is, various types of reasoning, and its role in decision making and social interactions. New to this edition is research on the influence of technology throughout the book, as well as a greater emphasis on the way that cultural backgrounds and variations in our exposure to information influence our thinking. This will enhance the scope, relatability, and diversity of the book, making it more applicable to future practices and research.

  • Bacterial Infections of the Central Nervous System

    • 1st Edition
    • Karen L. Roos + 1 more
    • English
    "Bacterial Infections of the Central Nervous System" consolidates recent discoveries and best practices on diagnosis and treating infection to minimize morbidity and mortality. The book discusses advancements in neuroimaging techniques, diagnostic studies performed on cerebrospinal fluid, adjunctive therapy, and antimicrobial therapy. Beginning with pathogenesis and pathophysiology of bacterial CNS infections, the book reviews when to suspect a bacterial infection of the central nervous system. The majority of the chapters review specific disease entities, including meningitis, focal CNS infections (e. g., brain abscess, subdural empyema and epidural abscess), CNS diseases caused by selected infectious pathogens (Mycobacteria, Rickettsiae, Anaplasmataceae, Treponema pallidum, Borrelia burgdorferi and other Borrelia species), the neurological complications of infective endocarditis, suppurative venous sinus thrombosis, infections in the neurosurgical patient, bacterial etiologies of movement disorders, Guillain-Barre syndrome, toxin-mediated syndromes of the nervous system and infectious encephalopathy.

  • Endovascular Therapy for Intracranial Atherosclerotic Stenosis

    • 1st Edition
    • Ning Ma + 1 more
    • English
    Endovascular Therapy for Intracranial Atherosclerotic Stenosis presents selected cases of endovascular treatment for intracranial atherosclerotic stenosis (ICAS), providing detailed information on periprocedural medical management, endovascular strategies, device selection, and follow-up outcomes. The book serves to improve understanding of ICAS and share clinical experiences from high-volume stroke intervention centres with neuro-interventional... The book reviews recent developments in ICAS management and presents evidence that appropriate patient selection and peri-operative planning may contribute to the effectiveness of endovascular therapy for ICAS

  • Cognitive Remediation in Psychiatric Disorders Part B

    Other Conditions, Contexts and Considerations
    • 1st Edition
    • Volume 307
    • English
    Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • The Human Nervous System

    • 4th Edition
    • George Paxinos + 2 more
    • English
    The 4th Edition of the classic book The Human Nervous System continues to assemble contributions from world leaders in research on the brain, spinal cord and peripheral nervous system. This book has been edited by the best-known team of brain cartographers, and it has been completely revised to present the cutting edge of human neuroscience. The structure, connections and function are explained in depth, making this book essential to any student or scientist interested in brain anatomy and function.

  • Central Nervous System Viral Infections

    • 1st Edition
    • Karen L. Roos + 1 more
    • English
    Central nervous system viral infections pose one of the greatest threats to humanity, as evidenced by recent history with SARS-CoV-2 (COVID 19), HIV, and others. Understanding their effects, therapeutics, and prevention are a top priority for all. "Central Nervous System Viral Infections" reviews the mechanisms of viral infections, current viruses of interest, diagnosis, course, and therapeutics, as well as prevention. Post infection syndromes and complications are also reviewed. Coverage includes Covid, HIV, Zika, EBOLA, Marburg, Herpes, Measles, Mumps, Polio, and more.

  • Basic Neurochemistry

    Principles of Molecular, Cellular, and Medical Neurobiology
    • 9th Edition
    • Scott Brady + 1 more
    • English
    Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, Ninth Edition is a classic advanced neurochemistry and neurobiology textbook that has a renewed focus on clinical applications. The early chapters focus on fundamental membrane chemistry, cellular signaling, and development of the nervous system. Later chapters cover cell injury and inflammation, neurodegenerative diseases, sensory transduction, and neural processing/behavior. By understanding mechanisms at the molecular and systems level, scientists can develop new pharmacotherapies to treat diseases such as Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis as well as neuropsychiatric diseases (e.g., schizophrenia, depression, pain, addictions).This book provides a foundation of all key principles of neurochemistry and neurobiology--within the context of human diseases--for advanced students and graduate students in neuroscience, biomedical sciences, as well as clinical neuroscientists and neurologists.

  • Inherited Metabolic Diseases and the Brain

    • 1st Edition
    • Fanny Mochel + 2 more
    • English
    Inherited Metabolic Diseases and the Brain explores the latest research on the neurological aspects of inherited metabolic diseases such as epilepsy, encephalotomy and more. With a strong research driven foundation and clinical applications, this book provides a primer which will help practicing pediatric and adult neurologists recognize, diagnose and treat neurometabolic disorders. This volume will also present a number of more common disorders in more detail, describing the variability in clinical presentation, the life course of the disease and the intricacies of diagnosis and treatment.

  • The Neurobiological Underpinnings of Addiction Medicine

    Focusing on Novel Approaches
    • 1st Edition
    • Mohammad Shabani + 3 more
    • English
    The Neurobiological Underpinnings of Addiction Medicine: Focusing on Novel Approaches provides a comprehensive review of the biological mechanisms that drive addiction and innovative strategies for treatment. This book begins by examining the crucial role of the microbiome and the gut-brain axis in various substance use disorders, including opioid, alcohol, neurostimulant, and cannabis use disorders. It highlights how gut health can significantly influence addiction behaviors and treatment outcomes. Following this, the second section discusses the interplay between addiction and neuropsychiatric disorders such as depression, anxiety, schizophrenia, ADHD, bipolar disorder, PTSD, and OCD.This section emphasizes the impact of neurotransmitter systems and intracellular pathways on the development and persistence of these disorders. The final section introduces cutting-edge methodologies reshaping addiction research, including multi-OMICS approaches and the implications of CRISPR-Cas9 technology. By integrating these diverse topics, this book offers vital insights for clinicians and researchers alike.

  • Neurosurgical Neuropsychology

    The Practical Application of Neuropsychology in the Neurosurgical Practice
    • 2nd Edition
    • Caleb M. Pearson + 2 more
    • English
    The second edition of Neurosurgical Neuropsychology: The Practical Application of Neuropsychology in the Neurosurgical Practice offers an in-depth review of the critical role neuropsychology plays in neurosurgical settings. This comprehensive resource covers essential preoperative techniques, including advanced functional neuroimaging methods such as fMRI and connectivity-based imaging, alongside traditional approaches like neurocognitive testing and the Wada procedure. This book highlights the significant contributions of neuropsychologists to the neurosurgical team, emphasizing their value in managing diverse patient populations, from candidates for Deep Brain Stimulation to those undergoing adult and pediatric epilepsy surgeries and neuro-oncology interventions. New chapters in this edition address contemporary topics such as the cognitive impact of epilepsy and epilepsy surgery, concussion, neuroplasticity, and the future role of artificial intelligence in neurosurgery. By updating existing content and incorporating fresh insights, this book serves as an essential guide for neurosurgeons, neuropsychologists, neuro-oncologists, epileptologists, and general neurologists who wish to enhance their understanding of neuropsychology's application in both preoperative and postoperative care.

  • Neuroinflammation and Biomarker Discovery

    From Mechanisms to Clinical Application
    • 1st Edition
    • Arun Kumar Singh + 1 more
    • English
    Neuroinflammation and Biomarker Discovery: From Mechanisms to Clinical Application offers a detailed exploration of the molecular and cellular processes underlying neuroinflammatory conditions. This essential reference addresses the urgent need for advanced biomarkers that can facilitate early diagnosis, monitor disease progression, and guide personalized treatments in neurodegenerative and autoimmune disorders such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. The book synthesizes current knowledge on neuroimmune interactions, glial cell activation, blood-brain barrier integrity, and innate immune signaling pathways, providing a comprehensive framework for understanding neuroinflammatory mechanisms. It also covers state-of-the-art platforms for biomarker discovery, including transcriptomics, proteomics, lipidomics, epigenomics, extracellular vesicles, and neuroimaging techniques, emphasizing their translational potential. The inclusion of disease-specific biomarker landscapes enhances its relevance for clinicians and researchers working in diagnostics and drug development. The final sections focus on translational applications, such as clinical trial design, biomarker validation, and the integration of AI-driven multi-omics data for personalized neuroimmunology. This volume is an indispensable resource for neuroscientists, clinicians, graduate students, biotech professionals, and data scientists seeking to advance understanding and innovation in neuroinflammatory research and clinical practice. By bridging basic science and clinical application, it aims to accelerate the development of targeted therapies and diagnostic tools, ultimately improving patient outcomes in neuroinflammatory diseases

  • Neurochemical Substrates of Addiction Medicine

    • 1st Edition
    • Mohammad Banazadeh + 2 more
    • English
    Neurochemical Substrates of Addiction Medicine offers an in-depth exploration of the complex interplay between neurochemistry and addiction, providing critical insights for researchers, clinicians, and students alike. This book is structured into four comprehensive sections, beginning with an examination of the distribution of neurotransmitters across key brain circuitry involved in addiction, such as the mesolimbic, striatal, frontal, insular, and thalamic systems. Each chapter meticulously describes how these circuits contribute to addictive behaviors and the underlying neurobiological mechanisms. The second section delves into the major neurotransmitter systems—including dopaminergic, glutamatergic, GABAergic, adrenergic, serotonergic, cholinergic, endogenous opioid, and purinergic systems—highlighting their roles in addiction.Following this, the book addresses the neuropharmacology of various drugs of abuse, including nicotine, opioids, alcohol, psychomotor stimulants, cannabinoids, psychedelics, sedative-hypnotics, caffeine, and antihistamines, detailing how these substances alter neurochemical pathways. The final section expands the discussion to behavioral addictions, exploring the neurochemical substrates associated with disorders such as pathological gambling, internet use, sexual addiction, and binge eating.

  • Primer on Cerebrovascular Research

    • 1st Edition
    • Dong-Eog Kim + 3 more
    • English
    Primer on Cerebrovascular Research provides both clinical and basic cerebrovascular knowledge that is required for physicians, vascular researchers, biomedical students, and trainees to understand or conduct evidence-based clinical practice and cutting-edge experimental research. This book outlines how to a design experimental cerebrovascular research in the context of clinical relevance, conduct the study using proper methods, analyze the data accurately, and make conclusions in an unbiased and statistically correct way. Chapters will include representative examples and experimental protocols.

  • Neurobiology of Depression

    Road to Novel Therapeutics
    • 2nd Edition
    • Joao L. de Quevedo + 2 more
    • English
    Neurobiology of Depression: Road to Novel Therapeutics, Second Edition provides the latest research advances, including interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the novel optogenetic techniques revolutionizing depression research. This new edition aids advanced students and researchers in their understanding of MDD, presenting chapters that explore groundbreaking topics such as the neurobiology of treatment-resistant depression, the mechanisms that make ketamine a better antidepressant, and the link between depression and Alzheimer's disease. Additionally, it covers the neurobiology of suicide in depression, the impact of psychedelics as therapy, and the unique aspects of bipolar depression.The book also examines computational models in depression, the neurobiology of psychotherapy, and the putative mechanisms of action for vagus nerve stimulation as a therapeutic approach. These additions help provide a broader and more comprehensive understanding of depression and its treatment.

  • The Alzheimer’s Spectrum: From Neural Stress to AI-Driven Care

    • 1st Edition
    • Volume 192
    • English
    The Alzheimer’s Spectrum: From Neural Stress to AI-Driven Care, published as Volume 192 of the serial International Review of Neurobiology, provides a comprehensive and multidisciplinary examination of Alzheimer’s disease (AD) across its biological, psychological, and technological dimensions. This volume integrates current research on neuropsychiatric factors such as depression, stress, and anxiety with advances in neuroanatomy, systems neuroscience, and emerging AI-driven diagnostic and therapeutic approaches. Chapters explore key brain regions and circuits implicated in AD—including the thalamus, prefrontal cortex, hippocampus, and memory-emotion networks—while also addressing comorbidities, extracellular vesicles as biomarkers, and innovative treatment strategies. The inclusion of computational approaches, model organisms, and novel therapeutic avenues reflects a strong translational focus, bridging mechanistic understanding with clinical and digital health applications. Collectively, this volume serves as an authoritative resource for understanding the Alzheimer’s continuum from early cognitive impairment to advanced disease and care optimisation.

  • Epigenetics and miRNA in Neurodegenerative Diseases

    From Molecular Mechanisms to Clinical Applications
    • 1st Edition
    • Lance R. McMahon + 2 more
    • English
    Epigenetics and miRNA in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications explores the crucial role of epigenetic modifications and microRNAs in the onset, progression, and treatment of neurodegenerative disorders such as Alzheimer’s, Parkinson’s, ALS, and Huntington’s disease. This comprehensive book bridges cutting-edge molecular research with real-world clinical applications, covering biomarker discovery, novel therapeutics, gene editing, and AI-driven bioinformatics. With clear explanations, case studies, and future perspectives, it serves as an essential resource for researchers, clinicians, and biotech professionals working toward innovative solutions for neurodegenerative disease diagnosis and treatment

  • Algorithmic Approaches for the Diagnosis of Common Neurological Emergencies

    • 1st Edition
    • Gentle Sunder Shrestha + 3 more
    • English
    Algorithmic Approaches for the Diagnosis of Common Neurological Emergencies is a practical resource aimed at clinicians working in the field of neurology. By providing an algorithmic approach to diagnosing patients, this volume helps clinicians quickly and systematically approach patients, minimizing the risk of missing common neurological emergencies. Offering case studies and various common neurological scenarios, readers will be able to pick up on warning signs of serious neurological emergencies and treat patients effectively. Users will find this to be a valuable guide to help manage patients with neurological emergencies with limited resources.

  • The NeuroComplex Interaction of Appetite Regulation

    Brain, Body and Environment
    • 1st Edition
    • Nasrollah Moradikor + 1 more
    • English
    The NeuroComplex Interaction of Appetite Regulation: Brain, Body and Environment presents the latest research on why we eat, what makes us hungry, and how our brain controls our cravings. The book covers the data for how the brain, hormones, and different factors such as stress, the environment, and even food itself affects our desire to eat. Written for academics and researchers, this book helps facilitate a comprehensive understanding on how the brain influences appetite regulation, allowing readers to understand how neurobiological mechanisms can help treat patients involved with obesity, eating disorders, or other related conditions.Readers will find this to be a reliable resource that connects current neuroscience research with practical applications in appetite and behavior.

  • Tourette Syndrome and Other Tic Disorders

    • 1st Edition
    • Mariam Hull
    • English
    The Neuroscience of Tourette's Syndrome and Other Tic Disorders provides a foundation of the latest research into tic disorders and the brain, as well as including a comprehensive framework for the evaluation of tics. Authors across multiple specialties present the most thorough and latest knowledge of Tourette syndrome to include underlying pathophysiology, clinical presentation, how to differentiate it from other tic disorders, particularly functional tics. Clinical case studies will also feature throughout to outline challenging cases with expert commentary on evaluation and management strategies.

  • Lysosomal Pathophysiology of Parkinson’s Disease

    • 1st Edition
    • Mattia Volta + 1 more
    • English
    Lysosomal Pathophysiology of Parkinson’s Disease delves into the genetic and genomic revelations that have transformed our understanding of Parkinson’s Disease at the molecular level. The book highlights the critical role of the autophagy-lysosome pathway in the disease's pathogenic processes, drawing a comprehensive timeline of disease onset and progression. It offers a detailed examination of how disruptions in this pathway contribute to the hallmarks of Parkinson’s Disease, providing invaluable insights for researchers and clinicians alike. Subsequent chapters extend these insights by comparing Parkinson’s Disease to other neurodegenerative disorders such as Alzheimer’s Disease and Frontotemporal Dementia. By exploring protein pathology and synaptic alterations, the book underscores the broader implications of autophagy-lysosome dysfunction. Additionally, it discusses how the molecular perspectives gleaned from Parkinson’s Disease can inform our understanding of these other conditions, presenting a unified approach to studying neurodegeneration.

  • Precision Functional Mapping

    From Human Neuroscience to Engineering
    • 1st Edition
    • Prantik Kundu
    • English
    Precision Functional Mapping explores next-generation functional neuroimaging techniques, focusing on the pursuit of accuracy and scalability in understanding the human brain, to the extent of enabling individual-subject level insights on brain function. Precision Functional Mapping: From Neuroscience to Engineering provides a clear and practical guide to implementing precision functional mapping. It uniquely balances the theoretical foundations of advanced functional neuroimaging with actionable strategies for implementation. With an emphasis on precision, scalability, and practical relevance, it addresses both current limitations and future possibilities in the field. By focusing on underexplored areas such as sparsity, temporal precision, and regulatory considerations, it offers a fresh perspective. Readers interested in neuroscience research, clinical applications, or technology development will find this book gives them tools and insights to push the boundaries of what is possible with functional neuroimaging.

  • Neuroreceptors

    Physiology, Pathology, and Therapeutic Targeting
    • 1st Edition
    • Deepa S. Mandlik + 1 more
    • English
    Neuroreceptors: Physiology, Pathology, and Therapeutic Targeting offers an in-depth exploration of the cellular and molecular mechanisms underlying brain receptor function and their critical roles in health and disease. This authoritative reference addresses ionotropic, metabotropic, receptor tyrosine kinases, and nuclear receptors, detailing their structures, signaling pathways, and physiological functions. The book emphasizes how receptor malfunctions contribute to neurological and psychiatric conditions such as Parkinson’s disease, Alzheimer’s, schizophrenia, and epilepsy, bridging fundamental biology with clinical relevance. Through comprehensive coverage of experimental methodologies—includ... imaging, electrophysiology, and molecular pharmacology—it equips researchers and clinicians with practical insights for investigating receptor dynamics and developing targeted therapies. The final sections focus on innovative therapeutic strategies, including gene editing, receptor modulation, and personalized medicine approaches, reflecting current advances in translational neuroscience. This resource is designed to serve as a vital tool for scientists, healthcare professionals, and students seeking a cohesive understanding of receptor biology and its therapeutic potential, fostering progress in neuropharmacology and neurotherapeutics

  • Brain Point-of-Care Ultrasound

    Practical Guide and Protocols
    • 1st Edition
    • Camilo N. Rodríguez + 6 more
    • English
    Brain Point-of-Care Ultrasound: Practical Guide and Protocols explores brain hemodynamics and parenchyma examination, providing an orderly and protocolized approach that facilitates individualized clinical decisions with ease. Covering ultrasound configuration, in-depth anatomical knowledge, and advanced parameters, this guide aims to integrate brain ultrasound seamlessly into the Point-of-Care Ultrasound (POCUS) modality, addressing the critical need for comprehensive patient assessment. From basic principles to specialized clinical situations, each section of this guide is meticulously crafted to empower practitioners with practical insights. Chapters explore Doppler spectral wave interpretation, angle correction nuances, autoregulation dynamics, and non-invasive pressure estimations, among others, thus enabling precise monitoring and targeted decision-making. With a focus on integration across disciplines and specialties, this book bridges the gap between classical pathology and contemporary practice, positioning brain ultrasound as a pivotal tool in the armamentarium of modern critical care.

  • Protein Misfolding

    • 1st Edition
    • Timir Tripathi
    • English
    Protein Misfolding explores the structural and biochemical foundations of protein misfolding, highlighting its wide-reaching implications for cellular function, disease progression, and biomedical innovation. This book provides a comprehensive understanding of how proteins deviate from their native conformations and the resulting biological consequences. Focusing on both physiological and pathological misfolding, the volume covers essential topics such as folding quality control, molecular chaperones, degradation pathways, and proteostasis. It presents in-depth analyses of protein aggregation mechanisms, amyloid formation, and misfolding-associate... diseases including Alzheimer's, Parkinson's, and prion-related disorders. Additional chapters explore structural approaches to understanding misfolded states, computational modeling of aggregation kinetics, and current efforts to design therapeutics that restore folding homeostasis or prevent toxic accumulation. The book also addresses the cellular response to misfolding stress and the integration of folding dynamics with cellular signaling pathways.This book is a valuable resource for researchers, educators, and professionals in biochemistry, structural biology, molecular medicine, biotechnology, and related disciplines. It supports efforts to understand the fundamental principles of protein structure and function, while offering insight into emerging therapeutic strategies and future research directions in disease-focused protein science.

  • Gold Nanoparticle Therapeutics in Alzheimer's Disease

    Revolutionizing Diagnosis and Treatment
    • 1st Edition
    • Arun Kumar Singh + 2 more
    • English
    Gold Nanoparticle Therapeutics in Alzheimer's Disease: Revolutionizing Diagnosis and Treatment is an essential resource that delves into the groundbreaking use of nanotechnology in the fight against one of the most challenging neurodegenerative disorders. This volume offers an in-depth exploration on how gold nanoparticles can be used to enhance the diagnosis, treatment, and overall understanding of Alzheimer's disease. By examining the molecular mechanisms that enable nanoparticles to cross the blood-brain barrier, the book highlights their role in inhibiting amyloid fibrils and their potential as precise diagnostic tools.Covering a wide range of topics, this comprehensive guide serves as an invaluable reference for researchers, clinicians, and industry professionals at the forefront of Alzheimer's research and nanomedicine.

  • Complications in Neuroanesthesia

    • 2nd Edition
    • Hemanshu Prabhakar
    • English
    Complications in Neuroanesthesia, Second Edition offers an extensive examination of the complications associated with neuroanesthesia practice, emphasizing both new and existing challenges in the field. This updated edition introduces critical topics such as locked-in syndrome, cerebellar mutism syndrome, delirium, awareness, memory loss, perioperative stroke, and coma, alongside established complications like brain herniation, hydrocephalus, and seizures. Each complication is meticulously examined in separate chapters, detailing the pathophysiology, mechanisms, diagnosis, treatment, and prevention strategies. This book also addresses cardiovascular issues, including stunned myocardium, as well as fluid and electrolyte disturbances like glucose dysregulation and conditions like post-dural puncture headache, malignant hyperthermia and reperfusion injury. Written in an accessible format for quick navigation, this resource provides invaluable insights into the perioperative management of neurosurgical and neurologic patients. This book is a practical tool for trainees, clinicians, and researchers in anesthesia, neuroanesthesia, neurosurgery, neurocritical care, and neurology. By highlighting preventable mishaps, this edition aims to enhance the safety and efficacy of neuroanesthesia and neurocritical care practice.

  • Animal Cognition

    Fundamentals, Models, and Therapeutic Advances
    • 1st Edition
    • Shampa Ghosh + 3 more
    • English
    Animal Cognition: Fundamentals, Models, and Therapeutic Advances provides a comprehensive overview of cognitive processes in various animal species, spanning fundamental concepts, species-specific studies, and therapeutic applications. Sections cover the foundation of animal cognition, including definitions, key concepts, and an overview of cognitive abilities, such as memory, problem-solving, and learning, delve deeper into the cognitive processes in mammals, birds, and marine animals, and more, and review the latest technological advancements in studying cognition, such as neuroimaging, machine learning, and virtual reality. With a multidisciplinary approach, this volume highlights current research while identifying gaps for future exploration, and will be of interest to researchers involved in animal cognition and behavioral neuroscience.

  • Epigenetic Mechanisms at the Crossroads of Development, Immune Response, and Neuropathology

    • 1st Edition
    • Varun Sasidharan Nair + 1 more
    • English
    Epigenetic Mechanisms at the Crossroads of Development, Immune Response, and Neuropathology offers an in-depth exploration of how epigenetic mechanisms shape neural development, immune interactions, and disease progression in the central nervous system. This interdisciplinary volume synthesizes current knowledge across neuroscience, immunology, and pathology, addressing the critical need for integrated frameworks that connect molecular regulation with clinical outcomes. The book covers foundational epigenetic processes such as DNA methylation, histone modifications, and non-coding RNAs, illustrating their roles in neural differentiation, circuit formation, and brain plasticity.It further examines how environmental factors influence epigenetic landscapes, impacting resilience and vulnerability to neuropsychiatric and neurodegenerative disorders. The volume also delves into the epigenetic drivers of neuropathologies including glioblastoma, neuroinflammation, and neurodegeneration, highlighting emerging therapeutic strategies. With contributions from leading international experts, this resource bridges basic science and translational research, providing valuable insights for researchers, clinicians, and advanced students seeking to understand and target complex CNS disorders.

  • Rhythmic Regulation in Neuroscience and Clinical Practice

    • 1st Edition
    • Barbara Minton + 2 more
    • English
    Rhythm and Entrainment in Neuromodulation covers cutting-edge and up-to-date information on currently available rhythm-related treatment procedures, as well as the interplay between music and cognition. The book contains contributions from leading experts in the across several fields, exploring the ways in which rhythmic stimulation serves as a powerful neuromodulator, enhancing cognitive function and promoting healing. Best suited for clinicians and researchers interested in neuromodulation, this volume offers profound insights into how rhythm shapes our cognition, influences our well-being, and paves the way for innovative therapeutic practices.

  • A Guide to Brief Clinical Interventions in Inpatient and Abbreviated Settings

    • 1st Edition
    • Elaheh Ashtari + 3 more
    • English
    There are many resources available for evidence-based psychotherapies in outpatient and other long-term settings, but limited resources are available for inpatient and other brief settings. A Guide to Brief Clinical Interventions in Inpatient and Abbreviated Settings offers a problem-focused psychotherapeutic approach applicable to brief and long-term care settings. The text will this text will include explicit cultural considerations when applying brief treatment, and promote cultural responsiveness across treatment providers and care settings. This multimodal, evidence-informed handbook is intended for behavioral health and mental health practitioners alike who desire to deliver high quality interventions in time limited settings, such as acute and subacute inpatient units.

  • Biomarkers in Neurological Disorders and Treatment

    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Decoding the Brain: Biomarkers in Neurological Disorders and Treatment provides a comprehensive exploration of the latest advances in neurological biomarkers, detailing their discovery, validation, and application in clinical practice. By offering insights into the biological underpinnings of various neurological disorders, this book aims to bridge the gap between cutting-edge biomarker research and its practical implementation in patient care.

  • Neurobiology of Psychiatric Disorders: New Perspectives on Mental Illness Associated with High Penetrance Genetic Variants

    New Perspectives on Mental Illness Associated with High Penetrance Genetic Variants
    • 1st Edition
    • Noboru Hiroi
    • English
    "The Neurobiology of Psychiatric Disorders" provides a conceptually innovative framework to understand psychiatric disorders including autism spectrum disorders, schizophrenia, intellectual disability, bipolar disorder, and ADHD. This book will allow readers to learn diverse mechanistic bases of psychiatric disorders causally associated with genetic variants. Because rare genetic variants have unprecedentedly high levels of penetrance for psychiatric disorders, this book provides reliable genetic links and their mechanistic substrates, thereby providing the starting points of precision medicine.

  • Nanomedicine for Neurological Disorders

    Design, Delivery, and Clinical Perspectives
    • 1st Edition
    • Malik Zainul Abdin + 4 more
    • English
    Nanomedicine for Neurological Disorders: Design, Delivery, and Clinical Perspectives addresses the urgent need for innovative solutions in treating complex neurological and neurodegenerative diseases. As the global burden of conditions such as Alzheimer's, Parkinson's, multiple sclerosis, and brain tumors continues to rise, the scientific community faces the critical challenge of safely and effectively delivering therapeutics across the blood-brain barrier. This reference meets the needs of neuroscientists, clinicians, pharmaceutical scientists, and biomedical engineers seeking advanced strategies and translational insights in neuro-nanomedicine. The contents are structured to provide a comprehensive, interdisciplinary exploration of the field. Chapters cover the anatomy and connectivity of the human brain, the global burden and mechanisms of neurological disorders, conventional and nanomedicine-based drug delivery systems, and the intricacies of the blood-brain barrier. Readers will benefit from detailed analyses of nanocarrier engineering, stability, analytical techniques, toxicological safety, regulatory challenges, and artificial intelligence-driven drug design. Real-world case studies, clinical trial data, and future outlooks are presented alongside ethical and patient-centric considerations, ensuring a holistic perspective on the evolving landscape of neuro-nanomedicine. Nanomedicine for Neurological Disorders delivers essential benefits by bridging the gap between laboratory innovation and clinical practice. It equips readers with practical knowledge, foundational advances, and visionary insights to inspire new research directions, inform better decision-making, and accelerate the development of safer, more precise treatments for brain-related disorders. This reference is an indispensable resource for researchers, clinicians, and innovators at the forefront of neurological therapeutics.

  • Cognitive Remediation In Psychiatric Disrorders Part A: Core Psychiatric Conditions

    • 1st Edition
    • Volume 306
    • English
    Brain Rehabilitation in Psychiatric Disorders, Volume 301 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Chapters in this new release include Overview and Historical Perspective of Cognitive Rehabilitation, Fundamental Principles of Cognitive Remediation, Cognitive Rehabilitation in Attention Deficit-Hyperactivit... Disorder, Cognitive Rehabilitation in Autism Spectrum and Disorders, Cognitive Rehabilitation in Schizophrenia Spectrum and Psychosis Disorders, Cognitive Rehabilitation in Bipolar Disorders, Cognitive Rehabilitation in Mood Disorders (Depression), and much more.Additional sections cover Cognitive Rehabilitation in Mood Disorders (Anxiety), Cognitive Rehabilitation in Obsessive-Compulsive Disorders, Cognitive Rehabilitation in Trauma-related Disorders, Cognitive Rehabilitation in Eating Disorders, Cognitive Rehabilitation in Substance Use Disorders, Cognitive Rehabilitation in Behavioral Addiction Disorders (Gambling, Internet, Cognitive Rehabilitation for Patients Receiving ECT, Cognitive Rehabilitation in Disorders Affecting Cognition in Older Adults, Cognitive Rehabilitation in Personality Disorders, and Harnessing Technology to Revolutionize Cognitive Rehabilitation.

  • Neurogynecology and Associated Neurological Disorders

    • 1st Edition
    • Vishal K. Chavda + 2 more
    • English
    Neurogynecology and Associated Neurological Disorders addresses the emerging interdisciplinary field linking neurology and gynecology, focusing on how neurological disorders impact female reproductive health throughout the lifespan. The book covers foundational neuroanatomy, hormonal influences on neurological function, and specific disorders including headaches, epilepsy, pelvic neuropathies, and mental health conditions related to reproductive stages. It includes clinical guidelines, case studies, diagnostic tools, and treatment protocols tailored to hormonal phases and life stages. The integration of neurobiological mechanisms with gynecological considerations offers readers a robust framework for interdisciplinary collaboration.Reader... will find this to be a great reference that responds to the growing clinical need for integrated understanding and management of conditions such as menstrual migraines, pregnancy-related neuropathies, and menopausal neurological changes.

  • Blood-Based Biomarkers for Alzheimer's and Parkinson's Disease – Part A

    • 1st Edition
    • Volume 191
    • English
    Blood-Based Biomarkers for Alzheimer’s and Parkinson’s Disease, Volume 191 in the International Review of Neurobiology series, presents current advances and comprehensive reviews on the development and application of circulating biomarkers in neurodegenerative disorders. It brings together contributions from an international panel, highlighting emerging strategies for early detection, diagnosis, and monitoring of Alzheimer’s and Parkinson’s diseases. Chapters explore a wide range of topics, including the Diagnostic Potential of Exosomes in Neurodegenerative Diseases and Cancer, Blood Biomarkers of Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s and Parkinson’s Diseases, GFAP and the Genetic Code of Astrocyte Activation in Alzheimer’s Disease, and much more.Additional chapters cover Blood-Based Emerging Biomarkers in Early Detection and Diagnosis of Alzheimer’s Disease, Advances in Nanomaterial-Based Biomarker Detection for Neurodegenerative Diseases, Blood-Based Biomarkers in Alzheimer’s and Parkinson’s Disease: From Molecular Pathology to Therapeutic Potential, Blood-Based Biomarkers and Their Role in AD/PD Diagnosis, The Emerging Landscape of Circulatory Biomarkers in Alzheimer’s Disease, Biofluid-Based Biosensors, Biomarkers of Vascular Dementia and Alzheimer’s Disease, Silent Clues in Blood: Proteomic Approach for Alzheimer’s Disease, and more.

  • Diagnostic Application of Blood-based Biomarkers for Neurodegenerative Diseases

    • 1st Edition
    • Meenakshi Dhanawat + 4 more
    • English
    Diagnostic Application of Blood-based Biomarkers for Neurodegenerative Diseases is a comprehensive exploration of the pivotal role blood-based biomarkers play in diagnosing and managing neurological disorders. This comprehensive guide emphasizes the need for early detection and intervention in conditions such as Alzheimer’s disease, Parkinson’s disease, and neuroinflammation. Each chapter delves into specific biomarkers, including glial fibrillary acidic protein and neurofilaments, elucidating their diagnostic potential. This book highlights recent advancements in the application of blood biomarkers across various neurodegenerative diseases, underscoring the integration of artificial intelligence in biomarker discovery. By bridging research and clinical practice, it serves as an essential resource for professionals in diagnostic sciences, pharmaceutical research, and clinical pharmacology. Ultimately, this volume aims to reshape the landscape of early diagnosis, offering insights that promise to enhance personalized treatment strategies and improve patient outcomes in the fight against debilitating neurological disorders.

  • Neuroscience-Informed Psychoeducation (NIPE) for Brain and Mental Health

    Part D
    • 1st Edition
    • Volume 305
    • English
    Neuroscience-Informe... Psychoeducation (NIPE) for Brain and Mental Health series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Neuroscience-Informed Psychoeducation (NIPE) for Brain and Mental Health

    Part C
    • 1st Edition
    • Volume 304
    • English
    Neuroscience-Informe... Psychoeducation (NIPE) for Brain and Mental Health, Part B, Volume 300 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics such as Neuroscience-informe... Psychoeducation for Functional Neurological Disorder, Neuroscience-informe... Psychoeducation for Multiple Sclerosis, Neuroscience-informe... Psychoeducation for Neurodegenerative Disorders (Alz & PD) / Dementia, Neuroscience-informe... Psychoeducation for Traumatic Brain Injury, Neuroscience-informe... Psychoeducation for Epilepsy, Neuroscience-informe... Psychoeducation for Stroke, Neuroscience-informe... Psychoeducation for Movement Disorders, and much more.Additional chapters cover Neuroscience-informe... Psychoeducation for Therapy, Neuroscience-informe... Psychoeducation for Pharmacotherapy, Neuroscience-informe... Psychoeducation for Brain Stimulation, Neuroscience-informe... Psychoeducation for Cognitive Rehabilitation, Neuroscience-Informe... Psychoeducation as a Digital Neurotechnology Platform, Neuroscience-informe... Psychoeducation for Policy Making (Neurolaw), Neuroscience-informe... Psychoeducation to Promote Community Engagement, and more.

  • Motor Control Methods and Clinical Applications

    • 1st Edition
    • Robert Chen + 1 more
    • English
    Motor Control Methods and Clinical Applications provides a detailed review on the use of non-invasive brain stimulation to study motor control. Split into two distinct parts, this new volume covers the latest research in motor control, including real examples of these methods in a clinical setting. The first part covers advanced methods such as transcranial magnetic, electrical and ultrasound stimulation, long latency, spinal reflexes, multichannel EMG, and EEG-EMG analyses that can be used to examine and modulate the motor system. The second part of the book addresses the clinical applications of these methods.

  • Cranial Nerve Compression Syndromes

    A Multidisciplinary Guide to Management
    • 1st Edition
    • Florian Roser + 1 more
    • English
    Cranial Nerve Compression Syndromes: A Multidisciplinary Guide to Management is a comprehensive volume exploring the entire pathophysiology of cranial nerve pathologies, from diagnosis to treatment options. Following a multidisciplinary approach, this volume integrates perspectives from neurosurgery, neurology, radiology, and pain management from experts in the field. An ideal resource for clinicians and researchers, this volume discusses the latest research on multi-modality, collaborative, and cutting-edge treatment options, with advanced surgical techniques, including microvascular decompression and endoscopic procedures with clear guidance.

  • International Review of Neurobiology

    • 1st Edition
    • Volume 190
    • English
    International Review of Neurobiology, Volume 190 highlights new advances in the field, with this volume presenting an in-depth chapter on imaging the glymphatic system in Huntington’s disease. This contribution explores the benefits of multimodal imaging approaches and their clinical implications, offering insights into disease mechanisms and potential diagnostic strategies.This volume provides a focused and up-to-date perspective on neurobiological research, serving as a valuable resource for researchers and clinicians interested in neurodegenerative disorders and advanced imaging techniques.

  • Practice of Neurocritical Care in Resource Limited Countries

    • 1st Edition
    • Hemanshu Prabhakar + 2 more
    • English
    Practice of Neurocritical Care in Resource Limited Countries offers a comprehensive examination of the unique challenges and practical strategies for delivering neurocritical care in low- and middle-income countries (LMICs). As the prevalence of neurological emergencies continues to rise in these regions, this book addresses the critical need for effective management in resource constrained environments. It begins by exploring the landscape of neurocritical care, including common neurological emergencies and their epidemiology in LMICs. The content outlines foundational principles of patient assessment and monitoring, as well as advanced management strategies for conditions such as traumatic brain injury, stroke, and spinal cord injury. Special attention is given to the nuances of caring for diverse patient populations, including pediatric and geriatric patients. Additionally, this book highlights the essential role of pain management, and nutritional support, in neurocritical settings. With contributions from experts across various LMICs, this resource emphasizes innovative approaches to training and capacity building, empowering healthcare professionals to provide high-quality neurocritical care despite the challenges of limited resources. This book is an invaluable tool for clinicians and educators dedicated to improving outcomes for neurologically ill patients in lesser-resourced healthcare systems.

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