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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Enzymes in RNA Science and Biotechnology

      • 1st Edition
      • Volume 691
      • October 27, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 5 7 7 0 7
      • eBook
        9 7 8 0 4 4 3 1 5 7 7 1 4
      Enzymes in RNA Science and Biotechnology, Volume 691 in the Methods in Enzymology series, highlights new advances in the field, including chapters on Reverse transcriptase Part I (discovery, preparation, general utilization, MarathonRT for routine RT-PCR and for cDNA synthesis on challenging RNA templates Structured RNAs, repeat RNAs and more, Engineering TNA Polymerases Through Iterative Cycles of Directed Evolution, Reverse transcriptase Part II (RNA structure mapping and determination), RNA G-quadruplex (rG4) structure detection using RTS and SHALiPE assays, tRNA Structure-seq in vivo and in droplets, Capture the in vivo intact RNA structurome by CAP-STRUCTURE-seq, and more.

    • Radiation Oncology and Radiotherapy Part C

      • 1st Edition
      • Volume 180
      • October 25, 2023
      • English
      • Hardback
        9 7 8 0 3 2 3 9 9 0 0 7 3
      • eBook
        9 7 8 0 3 2 3 9 9 0 0 8 0
      Radiation Oncology and Radiotherapy Part C, Volume 180 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Image-guided Radiation Therapy of tumors in preclinical models, Methods to preserve correct dosimetry in small animal irradiators, Monitoring TGFbeta signaling in irradiated tumors, Pipeline to characterize the TCR repertoire of irradiated tumors, Pipeline to identify tumor neoantigens exposed by radiation, Methods to assess abscopal responses in mice, Monitoring the biodistribution of radiolabeled therapeutics in mice, and more. Additional chapters cover Methods to assess radiation-induced fibrosis in mice, Methods to assess radiation-induced cardiotoxicity in mice, Histological assessment of intestinal injury by radiation, Methods to investigate CNS involvement in irradiated mice, Methods to characterize the exosomal output of irradiated cancer cells, and more.

    • Therapy Resistance in Prostate Cancer

      • 1st Edition
      • Volume 20
      • October 24, 2023
      • Hisham Bahmad
      • English
      • Hardback
        9 7 8 0 4 4 3 1 6 0 3 2 5
      • eBook
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      • eBook
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      Therapy Resistance in Prostate Cancer: Mechanisms and Insights, Volume 20 highlights the main mechanisms that are responsible for therapy resistance in PCa allowing researchers and clinicians to have a synopsis of current options and therapies that can be proposed to overcome resistance. Understanding the mechanisms responsible for chemotherapy resistance helps researchers all over the world delve deeper into the pathways behind this resistance and potentially discover new therapeutic targets for PCa. Prostate cancer (PCa) is among the most diagnosed cancers in men worldwide, as well as one of the most common causes of cancer-related deaths.Despite the advances in treatment, the disease remains associated with poor survival and resistance to cytotoxic and targeted therapies.

    • Health Equity in Endocrinology, An Issue of Endocrinology and Metabolism Clinics of North America

      • 1st Edition
      • Volume 52-4
      • October 20, 2023
      • Sherita Hill Golden + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 3 6 4 5
      • eBook
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      In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Sherita Hill Golden and Rana Malek bring their considerable expertise to the topic of Health Equity in Endocrinology. Top experts discuss health disparities present in endocrinology and metabolism care, with the goal of achieving more equitable patient care in the areas of diabetes, women’s reproduction, obesity, and more.

    • Hemostasis Management of the Pediatric Surgical Patient

      • 1st Edition
      • October 19, 2023
      • Nina A. Guzzetta + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 4 5 9 9
      • eBook
        9 7 8 0 3 2 3 9 0 4 6 0 5
      Hemostasis Management of the Pediatric Surgical Patient provides knowledge on the emerging area of pediatric hemostasis and its management. It discusses aspects of perioperative blood management in the pediatric population, including how to accurately estimate and monitor bleeding and determine optimal treatment regimens for bleeding in pediatric surgical patients. It also provides information on the implementation of intraoperative blood conservation strategies, goal-directed transfusion therapy, and postoperative estimation of bleeding and thrombotic risks. This book is a valuable resource to pediatric practitioners and researchers who need comprehensive information on pediatric hematology, from basic physiology to pre-, intra- and postoperative care of pediatric patients. The coagulation system of children evolves with age as evidenced by marked physiological differences in the concentration of hemostatic proteins between children of different age groups and adults. Consequently, there are distinct differences in hemostatic management between adult and pediatric patients.

    • Diagnostic Molecular Pathology

      • 2nd Edition
      • October 18, 2023
      • William B. Coleman + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 2 2 8 2 4 1
      • eBook
        9 7 8 0 1 2 8 2 2 9 9 3 4
      Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease.

    • Advances in Physical Organic Chemistry

      • 1st Edition
      • Volume 57
      • October 17, 2023
      • English
      • Hardback
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      • eBook
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      Advances in Physical Organic Chemistry, Volume 57 presents the latest reviews of recent work in physical organic chemistry, providing a valuable source of information that is ideal not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. The book's hallmark is its quantitative, molecular level understanding of phenomena across a diverse range of disciplines.

    • Modern Methods of Drug Design and Development

      • 1st Edition
      • Volume 690
      • October 17, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 5 8 7 1 1
      • eBook
        9 7 8 0 4 4 3 1 5 8 7 2 8
      Modern Methods of Drug Design and Development, a volume in the Methods in Enzymology series highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Recombinant protein purification for structural and kinetic studies, Steady-state kinetic analysis of reversible enzyme inhibitors, Steady-State Enzyme Kinetics, Analysis of enzyme kinetic data using ICEKAT, NMR techniques in drug discovery, Dynamic simulations and pre-steady state kinetics to guide drug discovery, Design and assay of substrate-product analogues for racemases and epimerases, Sensitive high throughput methods to screen for P450 inhibition: A- MI complex forming drugs, and more. Other chapters cover Sensitive high throughput methods to screen for P450 inhibition: B-Heme loss causing drugs, Discovery and development of inhibitors of acetyltransferase Eis to combat Mycobacterium tuberculosis, Crystallographic fragment screening in academic cancer drug discovery, Fast fragment- and compound-screening pipeline at the Swiss Light Source, Chemical biology, enzymology and drug discovery, PROTACs, Proximity-Induced Pharmacology (PROTACs), and much more.

    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 116
      • October 13, 2023
      • Gregory S. Makowski
      • English
      • Hardback
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      • eBook
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      Advances in Clinical Chemistry, Volume 116, the latest release in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists.

    • Glycolysis

      • 1st Edition
      • October 13, 2023
      • Rita Ferreira + 2 more
      • English
      • Paperback
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      • eBook
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      Glycolysis: Tissue-Specific Metabolic Regulation in Physio-Pathological Conditions provides an integrated overview of glycolysis, spanning basic biochemistry, patho-physiology and therapeutic applications. The book also instructs in methods available to study the involvement of the glycolytic events in healthy biology and disease pathology. It begins with an overview of fundamental glycobiology followed by chapters dedicated to glycolysis physiology in organs and systems, pathologic conditions related to glycolytic alterations, glycolysis as a therapeutic target and in drug discovery efforts, and methodological approaches to advance new glycolysis research. Disease areas considered range from cancer to heart failure, diabetes, inborn glycolytic pathway defects, hematologic malignancies, osteoporosis, neurodegenerative diseases and viral Infections. Omics and computational modeling, interactive study methods, and glycolysis flux measurement are described in detail, with step-by-step descriptions of experimental protocols, set-up and analysis.

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