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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Resistance in Hematologic Malignancies and Cancer

      • 1st Edition
      • October 29, 2024
      • Lucia Messingerova + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 3 2 1 7 9 0 6
      • eBook
        9 7 8 0 4 4 3 2 1 7 9 1 3
      Resistance in Hematologic Malignancies and Cancer brings together the molecular, cellular, and biochemical basis/principles of various mechanisms of resistance to treatment in hematologic malignancies.Even though main mechanisms of resistance are the same in different types of tumours there are specific signalling pathways involved in resistance in hematological malignancies and of course specific treatmentsIn 11 chapters, Resistance in Hematologic Malignancies and Cancer describes the development of treatment resistance in hematological malignancies, the role of MiRNA in resistance, the role of the immune system in resistance prediction, as well as the latest knowledge from clinical research.It gives insight in the complex information about different mechanisms linkage in final loss of cell sensitivity to drug treatment, the orientation in metabolic pathways that could be involved in depressed leukemia cell resistance to drugs and gives information about causes of drug resistance in leukemia cells.By the multidisciplinary approach of the processing this book is a valuable resource for both health professionals, scientists and researchers, health practitioners, students, but will also enable members of the general professional public to orientate themselves in issues that are not directly in their area of expertise

    • The Three Functional States of Proteins

      • 1st Edition
      • November 17, 2024
      • Timir Tripathi + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 8 0 9 5
      • eBook
        9 7 8 0 4 4 3 2 1 8 1 0 1
      The Three Functional States of Proteins explores how structured proteins, intrinsically disordered proteins, and phase separated proteins contribute to the complexity of cellular life, and offers insights into their roles in both health and disease. It discusses the latest research findings and highlight groundbreaking discoveries and innovative methodologies used to study these protein states.Traditionally... the different states of proteins have been defined based on their structures and functions. However, it is becoming increasingly clear that these criteria alone may not be sufficient to capture the complex and multifaceted properties of these molecules. Definitions based on thermodynamics and kinetics are now recognized as potentially more appropriate for comprehensively understanding protein states. Emerging evidence indicates that under physiological conditions, a majority of proteins possess the capability to exist in and transition between the native, droplet, and amyloid states. These distinct states play crucial roles in various cellular functions, influenced significantly by their physicochemical and structural properties. The book also considers the interactions among these states and discusses how their internal organization as individual molecules, as well as their collective organization as molecular assemblies are stabilized. Furthermore, it examines the processes by which these states are formed and the cellular functions associated with each specific state.

    • Pathophysiological Aspects of Proteases in Cancer

      • 1st Edition
      • October 22, 2024
      • Sajal Chakraborti + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 3 0 0 9 8 1
      • eBook
        9 7 8 0 4 4 3 3 0 0 9 9 8
      Pathophysiological Aspects of Proteases in Cancer provides a comprehensive overview of the multifaceted field of proteases in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology. The book both gives insights on the general aspects of the role of proteases in cancer, their role as diagnostics and prognostics biomarkers, their impact on chemoresistance, and the future cutting-edge technologies like cocktail therapies and Cyber Knife technology. Given the breadth and depth of information covered in the respective contributions, the book will be immensely useful for researchers in oncology and working to identify targets for drug development.Multidis... in scope, the book bridges the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry, making it a thought-provoking read for basic and applied scientists engaged in biomedical research.

    • Advances in Host Genetics and Microbiome in Colorectal Cancer-Related Phenotypes

      • 1st Edition
      • Volume 112
      • October 11, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 2 2 9 0 0
      • eBook
        9 7 8 0 4 4 3 2 2 2 9 1 7
      Advances in Host Genetics and Microbiome in Colorectal Cancer-Related Phenotypes, Volume 112 in the Advances in Genetics series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as What we need in colorectal cancer research, and why?, Host Genetics and Microbiota procedures in colorectal cancer research, Host Genetics-associated mechanisms in colorectal cancer, Microbiota-associate... mechanisms in colorectal cancer, Inflammation regulation in colorectal cancer, Microbiota and detrimental protein metabolites in colorectal cancer, Microbiota and other detrimental metabolites in colorectal cancer, Microbiota and beneficial metabolites in colorectal cancer, and much more.

    • Reverse Vaccinology

      • 1st Edition
      • July 6, 2024
      • Jayashankar Das + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 3 9 5 4
      • eBook
        9 7 8 0 4 4 3 1 3 3 9 6 1
      Reverse Vaccinology: Concept, Methods, and Advancement presents the development strategy of new vaccines through genome sequencing bioinformatics analysis. This book promises to revolutionize vaccine development, especially for pathogens to which the classical applications of Pasteur’s principles have failed, and it is explained in detail in this book.This book is split into three sections: the first, Concept, brings the basis of reverse vaccinology, vaccine antigen discovery, and subunit vaccine; the second, Tools and Methods, describes immunoinformatic, proteomics for epitope-vaccine design, databases, network analysis, machine learning, and NGS-driven antigen screening technology; and the last one, Disease Case Study, discusses real-world examples in the development of new vaccines for diverse diseases.It is a valuable resource for bioinformaticians, researchers, students, and members of the biomedical and medical fields who want to learn more about a new and agile process for the development of new vaccines.

    • Correlative Light and Electron Microscopy V

      • 1st Edition
      • Volume 187
      • April 30, 2024
      • Thomas Müller-Reichert + 1 more
      • English
      • Hardback
        9 7 8 0 3 2 3 9 5 1 4 1 8
      • eBook
        9 7 8 0 3 2 3 9 5 1 4 2 5
      Correlative Light and Electron Microscopy V, Volume 187 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

    • Adrenal Gland

      • 1st Edition
      • Volume 124
      • February 23, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 1 9 4 0 0 9
      • eBook
        9 7 8 0 4 4 3 1 9 4 0 1 6
      Adrenal Gland, Volume 124 in the Vitamins and Hormones series, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

    • Anandamide in Health and Disease

      • 1st Edition
      • September 1, 2024
      • Bernard Le Foll
      • English
      • Paperback
        9 7 8 0 4 4 3 1 9 0 8 1 0
      • eBook
        9 7 8 0 4 4 3 3 0 2 5 6 5
      Anandamide in Health and Disease, a volume in the Molecular Mediators in Health and Disease: How Cells Communicate series, is a complete reference on the roles of anandamide in health and disease states. Following the characteristics of the series, this book provides a comprehensive overview of the effects of the mediator on human health.The book is divided into two parts, the first of which provides background information on biology, regulation, synthesis and degradation and modulation of anandamide. The second part is dedicated to covering the role of anandamide in various diseases. A comprehensive panel of authors cover several somatic and psychiatric disorders, such as anxiety disorders, mood disorders, psychosis and substance use disorders. Additionally, the role of anandamide across epilepsy, Alzheimer's disease, and digestive conditions is explored.Anandamide in Health and Disease is the perfect reference for bioscience researchers seeking to understand anandamide pharmacology, biochemistry, cellular, and molecular biology. Clinicians may also be interested in better understanding the wide-ranging health effects of the mediator.

    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 118
      • January 25, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 5 6 2 1
      • eBook
        9 7 8 0 4 4 3 2 9 5 6 3 8
      Advances in Clinical Chemistry, Volume 118, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, including chapters on Advances in Endotoxin Analysis, Molecular biology of SARS-CoV-2 and techniques of diagnosis and surveillance, Osteopontin in Cancer, Gastrointestinal Hormones: History, Biology, and Measurement, Natriuretic Peptide Testing Strategies in Heart Failure: a 2023 Update, and Defining Allowable Total Error Limits in the Clinical Laboratory.

    • Innovating Health Against Future Pandemics

      • 1st Edition
      • April 30, 2024
      • Simona Mellino + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 6 8 1 8
      • eBook
        9 7 8 0 4 4 3 1 3 6 8 2 5
      Innovating Health Against Future Pandemics covers the key aspects which drive heterogeneity in an individual's response to COVID-19, including age, sex, genetic makeup, immune responses, comorbidities, and viral strains/loads. This book also reviews the case examples from other disciplines to highlight areas where precision medicine and AI could be applied for the improvement of pandemic management. This includes research, primary and secondary prevention, isolation/tracking, hospitalization and patient management, diagnosis, and treatments. Lastly, drawing on past experiences for each of the areas this book provides practical recommendations to manage future pandemics.COVID-19 offered an unprecedented occasion to test the impact of digitally enabled solutions within precision medicine for public health and for accelerating their deployment and adoption.

Related subjects

Biochemistry biophysics

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Molecular biology cellular biology and genetics

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