Glycation
- 1st Edition, Volume 125 - July 11, 2024
- Imprint: Academic Press
- Editor: Gerald Litwack
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 9 4 0 2 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 9 4 0 3 - 0
Glycation, Volume 125 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international… Read more
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Request a sales quoteGlycation, Volume 125 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in Vitamins and Hormones serials
- Updated release includes the latest information on Glycation
Undergraduates, graduates, academics, and researchers in the field of vitamins and hormones
- Cover image
- Title page
- Table of Contents
- Editorial Board
- Copyright
- Former Editors
- Dedication
- Contributors
- About the editor
- Chapter One: The dynamic roles of advanced glycation end products
- Abstract
- 1 Introduction
- 2 Sources of AGEs
- 3 AGEs receptors
- 4 Downstream signaling of AGEs
- 5 Perspectives
- References
- Chapter Two: Methylglyoxal-induced modification of myoglobin: An insight into glycation mediated protein aggregation
- Abstract
- 1 Protein glycation
- 2 Glycation and protein aggregation
- 3 Structural alterations of myoglobin by methylglyoxal
- 4 Aggregation of myoglobin by methylglyoxal
- 5 Mass spectrometric analysis of MG modified Mb
- 6 Concluding remarks
- Acknowledgments
- References
- Chapter Three: Glycation in the cardiomyocyte
- Abstract
- 1 Glycation and the cardiomyocyte
- 2 Extracellular glycation
- 3 Glycation disrupts cardiomyocyte calcium handling
- 4 Glycation of the cytoskeleton
- 5 Other effects of glycation in the cardiomyocyte
- 6 Therapeutics and the future of cardiomyocyte glycation
- 7 Other future directions and concluding remarks
- References
- Chapter Four: Glycation and drug binding by serum albumin
- Abstract
- 1 Glycation
- 2 Glycation of transport protein serum albumin
- 3 Role of advanced glycation end products
- 4 Characterisation of glycated protein and glycation end-products
- 5 Glycation and protein conformation
- 6 Calorimetry in glycation studies
- 7 Glycation and drug binding
- 8 Future perspectives
- References
- Chapter Five: Advanced glycation end products and insulin resistance in diabetic nephropathy
- Abstract
- 1 Introduction
- 2 Advanced glycation end products
- 3 Receptors for AGEs
- 4 Role of AGEs in insulin resistance
- 5 AGEs and their involvement in diabetic nephropathy
- 6 Mechanisms of insulin resistance and its impact on the kidney
- 7 Inhibition of the AGE-RAGE axis: Treatments for diabetic nephropathy
- 8 Conclusion and future perspectives
- References
- Chapter Six: The Maillard reactions: Pathways, consequences, and control
- Abstract
- 1 Introduction
- 2 Stages of the Maillard reactions
- 3 Influencing factors
- 4 Consequences of the Maillard reactions
- 5 Strategies for controlling the Maillard reactions
- 6 Final considerations
- References
- Chapter Seven: Structural changes in hemoglobin and glycation
- Abstract
- 1 Introduction
- 2 Glycation of hemoglobin
- 3 Hb glycation: in vitro protocols evaluation
- 4 Structural changes in Hb after glycation
- 5 Techniques and methods for assessing structural and conformational changes in glycated Hb
- 6 Trends
- 7 Conclusions
- Acknowledgements
- References
- Chapter Eight: Attenuation of albumin glycation and oxidative stress by minerals and vitamins: An in vitro perspective of dual-purpose therapy
- Abstract
- 1 Introduction
- 2 Materials and methods
- 3 Methods
- 4 Results and discussion
- 5 Conclusion and future directions
- Acknowledgments
- References
- Chapter Nine: Non-enzymatic glycation and diabetic kidney disease
- Abstract
- 1 Kidney architecture
- 2 Kidney dysfunction in diabetes
- 3 Altered glucose homeostasis
- 4 Non-enzymatic glycation (NEG)- a post-translational modification
- 5 Fate of AGEs
- 6 Pathology of AGEs in DKD
- 7 Strategies to prevent AGEs formation and DKD
- 8 Summary and future perspective
- Acknowledgments
- References
- Chapter Ten: Nanoparticles in prevention of protein glycation
- Abstract
- 1 Introduction
- 2 Chemistry of the glycation reaction
- 3 Glycation of biological macromolecules
- 4 DNA glycation
- 5 RNA glycation
- 6 Lipid glycation
- 7 Clinical relevance of glycation and advanced glycation end products
- 8 Osteoporosis
- 9 Cancer
- 10 Neurodegenerative diseases
- 11 Cardiovascular diseases
- 12 Prevention of glycation
- 13 Nanotechnology approach for combating glycation
- 14 Nanoparticles
- 15 Gold nanoparticles
- 16 Silver nanoparticles
- 17 Zinc nanoparticles
- 18 Challenges and future perspectives
- 19 Challenges
- 20 Future perspectives
- 21 Conclusion
- References
- Chapter Eleven: Breath of fresh air: Investigating the link between AGEs, sRAGE, and lung diseases
- Abstract
- Abbreviations
- 1 Introduction
- 2 Chronic obstructive pulmonary disease
- 3 Asthma
- 4 Lung fibrosis
- 5 Cystic fibrosis
- 6 Acute lung injury/acute respiratory distress syndrome
- 7 Lung cancer
- 8 Unmasking RAGE’s complex role in lung cancer progression
- 9 Unlocking the impact of AGER polymorphisms on lung cancer
- 10 sRAGE: Illuminating lung cancer diagnosis and beyond
- 11 Conclusions and future directions
- References
- Chapter Twelve: Antioxidant and antibrowning properties of Maillard reaction products in food and biological systems
- Abstract
- 1 Introduction
- 2 Chemistry of the Maillard reaction
- 3 MRPs as antioxidants
- 4 MRPs as antibrowning agents
- 5 Deleterious effect of MRPs as glycation end products in biological systems
- 6 Conclusions
- Acknowledgments
- References
- Chapter Thirteen: Vitamin B6 and diabetes and its role in counteracting advanced glycation end products
- Abstract
- 1 Vitamin B6
- 2 Vitamin B6 and diabetes
- 3 Advanced glycation end products
- 4 Vitamin B6, diabetic complications and AGEs
- 5 Conclusions
- References
- Edition: 1
- Volume: 125
- Published: July 11, 2024
- No. of pages (Hardback): 460
- No. of pages (eBook): 300
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780443194023
- eBook ISBN: 9780443194030
GL
Gerald Litwack
Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)
Affiliations and expertise
Emeritus Founding Chair and Professor, Geisinger Commonwealth School of Medicine, United States
Emeritus Professor, Rutgers University, United StatesRead Glycation on ScienceDirect