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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Bioinformatics

      • 1st Edition
      • July 18, 2003
      • Zoé Lacroix + 1 more
      • English
      • Hardback
        9 7 8 1 5 5 8 6 0 8 2 9 0
      • eBook
        9 7 8 0 0 8 0 5 2 7 9 8 7
      Life science data integration and interoperability is one of the most challenging problems facing bioinformatics today. In the current age of the life sciences, investigators have to interpret many types of information from a variety of sources: lab instruments, public databases, gene expression profiles, raw sequence traces, single nucleotide polymorphisms, chemical screening data, proteomic data, putative metabolic pathway models, and many others. Unfortunately, scientists are not currently able to easily identify and access this information because of the variety of semantics, interfaces, and data formats used by the underlying data sources. Bioinformatics: Managing Scientific Data tackles this challenge head-on by discussing the current approaches and variety of systems available to help bioinformaticians with this increasingly complex issue. The heart of the book lies in the collaboration efforts of eight distinct bioinformatics teams that describe their own unique approaches to data integration and interoperability. Each system receives its own chapter where the lead contributors provide precious insight into the specific problems being addressed by the system, why the particular architecture was chosen, and details on the system's strengths and weaknesses. In closing, the editors provide important criteria for evaluating these systems that bioinformatics professionals will find valuable.

    • Progress in Nucleic Acid Research and Molecular Biology

      • 1st Edition
      • Volume 73
      • July 14, 2003
      • Kivie Moldave
      • English
      • Hardback
        9 7 8 0 1 2 5 4 0 0 7 3 2
      • eBook
        9 7 8 0 0 8 0 4 9 7 8 6 0
      Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences including genetics, biochemistry, and cell biology. Progress in Nucleic Acid Research and Molecular Biology is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume.

    • Prostate Cancer

      • 1st Edition
      • July 11, 2003
      • Jack H. Mydlo + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 2 8 6 9 8 1 5
      • eBook
        9 7 8 0 0 8 0 4 9 7 8 9 1
      An important translational book bridging the gap between science and clinical medicine, Prostate Cancer reviews the biological processes that can be implicated in the disease, reviews current treatments, highlighting the pitfalls where relevant and examines the scientific developments that might result in novel treatments in the future.

    • Advances in Enzyme Regulation

      • 1st Edition
      • Volume 43
      • July 10, 2003
      • George Weber
      • English
      • Hardback
        9 7 8 0 0 8 0 4 4 2 9 4 5
      • eBook
        9 7 8 0 0 8 0 9 1 3 7 3 5
      This volume contains papers of 23 outstanding scientists who are working at the leading edge of metabolic regulation studies. Much of the volume focuses on novel aspects of signal transduction with emphasis on the role of phospholipase C in cell control mechanisms. One of the highlights of this volume is always the Special Symposium Lecture. This lecture was given for fifteen years by Nobel laureate, Sir Hans A. Krebs (UK) (now deceased). This year the Lecture was given by Nadir Maraldi, Director of the Laboratory of Cellular Biology and Electron Microscopy, University of Bologna, Italy. Professor Maraldi's presentation is on the important and novel subject of "Nuclear Proteins and Human Disease."

    • Neurons: Methods and Applications for the Cell Biologist

      • 1st Edition
      • Volume 71
      • July 8, 2003
      • English
      • Paperback
        9 7 8 0 1 2 4 1 5 6 9 9 9
      • Paperback
        9 7 8 0 1 2 3 5 2 5 6 6 6
      • Hardback
        9 7 8 0 1 2 3 5 2 5 6 5 9
      • eBook
        9 7 8 0 0 8 0 4 9 6 6 3 4
      • eBook
        9 7 8 0 0 8 0 8 5 9 6 9 9
      Neurons: Methods and Applications for the Cell Biologist lays out numerous simple techniques for growing and carrying out experiments with many varieties of neurons. Subjects include peripheral and central neurons from vertebrate and invertebrate sources, as well as neuron-like cell lines. It also explains recent advances in our ability to introduce exogenous proteins and genes to neurons in culture. Procedures for successful protein infiltration, biolistic transfection, electroporation, and viral transgenic methods in neurons are also presented.

    • Developmental Biology Research in Space

      • 1st Edition
      • Volume 9
      • July 1, 2003
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 3 5 3 3
      • Paperback
        9 7 8 0 4 4 4 5 4 7 7 8 1
      • eBook
        9 7 8 0 0 8 0 4 9 4 4 7 0
      In this volume of ASPA, devoted to developmental biology research, 9 authors from different fields of developmental biology present their investigations on various developing plant and animal models. An a priori concern in mind that weightlessness might have negative effects on developmental processes, it is encouraging to know that the overall development of various organisms tested so far is essentially correct under spaceflight conditions, leading to viable individuals with viable offspring. On the other hand, particular studies on specifically neurophysiological aspects in developing organisms reveal important flight or postflight disturbances; however it is encouraging to know that they appear to be transient only.The book contains ten chapters, giving details on how, in technical terms, experiments for spaceflights are prepared, performed and analysed and on how, in scientific terms, the available results have to be interpreted. One contribution is devoted to plant systems, five consider the overall aspects of embryonic development in invertebrates and vertebrates, two focus on neurophysiological aspects and one reports on the "mother-offspring system" in weightlessness in a mammalian model, the last chapter presents new ESA facilities and instruments to be integrated into the European research Laboratory "Columbus" of the ISS.

    • Vitamins and Hormones

      • 1st Edition
      • Volume 66
      • June 20, 2003
      • Gerald Litwack
      • English
      • Hardback
        9 7 8 0 1 2 7 0 9 8 6 6 1
      • eBook
        9 7 8 0 0 8 0 4 9 2 4 3 8
      First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

    • Membrane Lipid Signaling in Aging and Age-Related Disease

      • 1st Edition
      • Volume 12
      • May 6, 2003
      • M.P. Mattson
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 7 7 9 8
      • Hardback
        9 7 8 0 4 4 4 5 1 2 9 7 0
      • eBook
        9 7 8 0 0 8 0 5 2 2 5 0 0
      The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume reveal striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative disorders. Lipids including inositol phospholipids, cholesterol, sphingolipids and ceramides play important roles in signalling cellular responses to stress and specific stimuli such as growth factors, cytokines and neurotransmitters. One or more of these lipid mediators has been linked to the pathogenesis of age-related diseases. This book provides a comprehensive review of specific membrane lipid mediators and their roles in aging and age-related disease.

    • Basic Biology and Clinical Impact of Immunosenescence

      • 1st Edition
      • Volume 13
      • May 1, 2003
      • G. Pawelec
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 7 8 0 4
      • Hardback
        9 7 8 0 4 4 4 5 1 3 1 6 8
      • eBook
        9 7 8 0 0 8 0 5 4 6 4 8 3
      Ageing is of perennial interest as a universal feature in all human societies. The genetic background and biochemical bases of ageing processes are currently being revealed in unprecedented detail. It is emerging that one of the main hurdles to be overcome in achieving a long and healthy lifespan is the maintenance of a properly functioning immune system. The main cause of death in people who have achieved "successful ageing" (which mostly means not having succumbed to cancer or cardiovascular disease) is infectious disease, caused by immunosenescence. This book contains chapters by many of the leaders in the field of immune-related issues in ageing and remediation.

    • Boxing

      • 1st Edition
      • April 22, 2003
      • Friedrich Unterharnscheidt + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 7 0 9 1 3 0 3
      • eBook
        9 7 8 0 0 8 0 5 2 8 2 5 0
      This book neither argues for or against the continuation of boxing, but lays out the literature and the body of scientific knowledge that are necessary to provide a meaningful background for the ensuing debate. It provides a comprehensive resource for those who are involved in regulating boxing and those who participate directly, as well as for the medical and scientific communities. Includes carefully quoted case histories and research as well as an extensive body of medical literature on boxing injuries to demonstrate that brain damage is a natural consequence of boxing.

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