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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • CRISPR Handbook

      • 1st Edition
      • November 15, 2024
      • Zhi-Yan Du
      • English
      • Paperback
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      • eBook
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      CRISPR Handbook: Applications, Tools and Resources presents a detailed introduction to the CRISPR technology. This handbook summarizes the current CRISPR applications in diverse organisms, shares useful tools for starting a CRISPR experiment, and provides information on software and services for CRISPR technology.Written by an expert in the field of biotechnology and molecular biology of diverse experiment models, including plants, microalgae, and fungi. This handbook will serve as a guide for those who are interested in learning about CRISPR technologies and their applications in research and industry.
    • Nanosensors in Healthcare Diagnostics

      • 1st Edition
      • November 13, 2024
      • Abhinay Sharma + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 9 1 2 9 9
      • eBook
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      Nanosensors in Healthcare Diagnostics examines the role of nanosensors in clinical microbiology, point-of-care sensing, clinical diagnostics, and therapy.This book addresses the concept of nanosensors and their utilization in healthcare diagnostics, and therapy. It covers the principles and mechanisms involved in nanosensor-based diagnostics platforms. It also discusses various approaches and techniques used in the preparation of nanosensors as well as the biomedical application of nanosensors in clinical diagnostics and their significance in the detection, treatment, and management of diseases. This book is a useful reference for researchers, graduate students, and industry professionals studying nanosensors in biological and medical sciences.
    • Revealing Uncharted Biology with Single Cell Multiplex Proteomic Technologies

      • 1st Edition
      • June 25, 2024
      • Wendy Fantl
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 2 0 9 6
      • eBook
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      Revealing Uncharted Biology with Single Cell Multiplex Proteomic Technologies: Platforms. Understanding the intricate coordination of highly diverse cell types within healthy tissues and organs is essential for grasping their functionality. This coordination, often disrupted in disease, hinges on proteins—the primary drivers of cellular function. By examining protein abundance and activation states in single cells, researchers can identify key cell populations involved in both healthy and diseased states, including those influencing disease initiation, progression, and therapeutic responses. Single-cell multiplex proteomic platforms have recently emerged as powerful tools for biomedical research. Their strengths lie in revealing cell types that are rare or subtly different and would otherwise go undetected in bulk cellular analyses. This unique capability enables deeper insights into cellular behavior and disease mechanisms.This book offers comprehensive overviews of technologies developed for multiplex single-cell proteomic analyses. It begins with the pioneering work from Professors Scott Tanner, Mitchell Winnick and Garry Nolan resulting in the development and early application of the mass cytometer, (CyTOF). The instrument merges flow cytometry with time-of-flight mass spectrometry and analyzes cells labelled with metal tagged antibodies. These components work together to enable CyTOF to perform highly multiplexed protein analysis at the single-cell level, offering a powerful tool for understanding complex cellular behaviors and interactions.Recogni... that cellular organization is critical for tissue function, subsequent chapters explore advanced multiplex imaging platforms including Imaging Mass Cytometry (IMC), Multiplexed Ion Beam Imaging (MIBI), CODetection by InDExing, and Chip Cytometry. Later chapters present recent advances in these imaging platforms and data analysis approaches - Combined Nucleic Acid and Protein Quantification in situ, Tissue Schematics, and High-definition CODEX for 3D Multiplex Spatial Cell Phenotyping. These techniques integrate deep phenotyping with spatial mapping to provide unprecedented insights into cellular interactions within tissues. The book also highlights computational approaches essential for managing and interpreting the vast datasets generated by these technologies. Revealing Uncharted Biology with Single Cell Multiplex Proteomic Technologies: Platforms help researchers in many fields, including developmental biology, cancer biology, immunology, neuroscience, and drug discovery gain an understanding about the theories and detailed methodologies behind these technologies. Integrating proteomics with genetic, epigenetic, and transcriptomic platforms, this book aims to inspire new research opportunities, ultimately advancing the development of reliable biomarkers and improving patient outcomes.
    • Ureases

      • 1st Edition
      • February 16, 2024
      • Rodrigo Ligabu Braun + 1 more
      • English
      • Paperback
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      • eBook
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      Ureases: Foundations, Classes, and Applications provides a thorough, practical analysis of ureases—enzymes of growing relevance across a range of biotechnological applications and drug discovery. Unique in many aspects, ureases are one of the few enzymes to have nickel in their active sites. This book covers all aspects of this enzymatic class starting with foundational overview and then providing historical urease research and current state, from basic biochemistry to the use of ureases as hallmarks in enzymology, crystallography, and bioinorganic chemistry. The different classes of ureases, structurally diverse but chemically equivalent, are individually discussed.The multi-protein, multi-step activation of ureases (with chemical modification of residues, transport, and transfer of nickel ions) are examined in-depth, along with the catalytic mechanisms of ureolysis and its inhibitors. The final two sections of the book address multiple applications of ureases in health and biotechnology, respectively, going from gastric ulcer treatment to architectural uses in buildings and engineering. Future applications and next steps in research are also considered.
    • Anoxygenic Phototrophic Bacteria

      • 1st Edition
      • March 22, 2024
      • Keizo Shimada + 1 more
      • English
      • Paperback
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      • eBook
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      Anoxygenic Phototrophic Bacteria is a comprehensive overview of phototrophic bacteriacovering the following: overview of photosynthesis and phototrophic bacteria; systematicsand characteristics of each taxon; ecology and cultivation; photosynthetic electrontransfer systems; metabolism; pigments and lipids; light-harvesting systems and reactioncenters; photosynthetic genes and regulation of gene expression; origin and evolution ofphotosynthesis; and the utilization of phototrophic bacteria.Chapters are written by some of Japan’s leading researchers in the area, providing researchersin photosynthesis, bacterial physiology, microbial ecology, artificial photosynthesis,bioph... biochemistry, industrial chemistry a highly detailed, up-to-date and thoroughlycross-refe... book in this interdisciplinary area. With very few books being published overthe last 25 years on the topic, this book especially fills a crucial need for young researchersand those working at the margins of interdisciplinary fields.
    • Living Donor Organ Transplantation

      • 2nd Edition
      • January 18, 2024
      • Rainer W.G. Gruessner + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 5 7 1 9
      • eBook
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      **Selected for 2025 Doody’s Core Titles® in Transplantation Surgery**Living Donor Organ Transplantation, Second Edition puts the entire discipline in perspective while guiding readers step-by-step through the most common organ transplant surgeries. This two-volume set is organized into five cohesive parts, and featuring numerous surgical illustrations, this sourcebook delivers an incisive look at every key consideration for general surgeons who perform transplantations, from patient selection to recipient workup and outcomes. The books emphasize the most humanitarian approaches and provide content on living donor uterus transplantation, new operative techniques, including the use of robotic and minimally invasive transplant procedures, new immunosuppressive regimens, new protocols of tolerance induction, including stem cell therapy and transplantation, and more.Chapter authors are international leaders in their fields and represent institutions from four continents (Americas: USA, Argentina, Brazil, Canada; Europe: France, Germany, Italy, Spain, Sweden, UK; Asia: China, Japan, Korea, Taiwan; Australia).
    • Truth Unveiled

      • 1st Edition
      • November 23, 2024
      • Faadiel Essop
      • English
      • Hardback
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      • eBook
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      Faculty, students, researchers, and clinicians are struggling how to deal with the post-truth world as the broader public lacks an understanding of the complexity of the scientific research process. This has resulted in the dissemination of mis- and disinformation that is increasingly used to shape public opinion in medical-related matters, for example, the rise of anti-vaxxers and resistance to COVID-19 pandemic social isolation protocols. In addition, physiologists and scientists play relatively limited role when engaging the broader public in this regard. Truth Unveiled: Navigating Science and Society in an Era of Doubt provides valuable information to inform researchers and clinicians and better train students on the broader aspects of the scientific process and how to best counteract mis- and disinformation. This book is published as part of the Fundamentals of Physiology series in association with the International Union of Physiological Sciences and should be a useful resource for lecturers when training physiologists, biomedical scientists, and medical and allied health students.
    • Artificial Intelligence in Microbiology: Scope and Challenges Volume 1

      • 1st Edition
      • Volume 55
      • July 30, 2024
      • English
      • Hardback
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      • eBook
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      Nowadays, the field of microbiology is undergoing a revolutionary change due to the emergence of Artificial Intelligence (AI). AI is being used to analyze massive data in a predictable form, about the behavior of microorganisms, to solve microbial classification-relat... problems, exploring the interaction between microorganisms and the surrounding environment. It also helps to extract novel microbial metabolites which have been used in various fields like medical, food and agricultural industries. As the pace of innovation in Microbiology is accelerating, the use of AI in these industries will be beneficial. AI will not only show its extraordinary potential in expanding the market of antibiotics, food, and agriculture but also offer an eco-friendly, safer, and profitable solution to the respective industries. It would be challenging to search out specific features and discuss future research on AI in microbiology with a wide perspective.
    • The Charnolosome as a Novel Nanothereranostic Biomarker

      • 1st Edition
      • September 27, 2024
      • Sushil Sharma
      • English
      • Paperback
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      • eBook
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      The Charnolosome as a Novel Nanothereranostic Biomarker: Overcoming Future Challenges in Medicine provides an overview of the charnolosome and its potential as a biomarker of cell injury. Based on the author’s original discovery of the charnoly body in the developing, undernourished rat cerebellar Purkinje neurons, this book delves into the potential for utilizing this mitochondria and lysosomal-derived intracellular organelle as a nanotheranostic biomarker to prevent and cure various diseases.The book discusses the cellular, molecular, genetic, and epigenetic mechanisms of charnolosomes and charnolosome-derived nano-vesicles. It also investigates the molecular mechanisms underlying auto-inflammatory, autoimmune, and infectious diseases resulting from their compromised mitochondrial bioenergetics, and the potential use of the charnolosome in preventing and curing such conditions.
    • Artificial Intelligence in Urology

      • 1st Edition
      • October 15, 2024
      • Andrew J Hung
      • English
      Artificial Intelligence in Urology: Present and Future summarizes the cutting-edge development and adoption of Artificial Intelligence (AI) technologies in urology. The book explores barriers that prevent the further adoption of AI technologies, provides ethical considerations, and investigates the future role AI is expected to play. In addition, it includes applications of AI technology in the diagnosis and treatment of cancers (prostate, bladder, and more) and kidney stones, and in both adult and pediatric care. This is the perfect reference for researchers developing AI technologies for clinical applications and for clinicians who aim to effectively adopt AI technologies to solve clinical questions.