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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Control of Membrane Function: short-term and long-term

      • 1st Edition
      • December 2, 2012
      • J.M. Ritchie + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 7 1 4 7
      • eBook
        9 7 8 0 4 4 4 6 0 0 9 3 6
      A critical factor in cell-to-cell interactions is the presence in the cell membrane of highly specific ion channels controlled by specific receptors that are bound to, and activated by, a gamut of external hormones and neurotransmitters. Through both this action on ion channels, and action on other membrane components (such as G-proteins), extracellular signals alter intracellular events, usually through the mediation of second messengers, and so provide the basis for the transduction mechanism connecting extracellular signals with intracellular effectors. This volume deals with the various ways that such membrane function is controlled.

    • Interaction of Translational and Transcriptional Controls in the Regulation of Gene Expression

      • 1st Edition
      • December 2, 2012
      • Marianne Grunberg-Manago
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 9 2 4 0
      • eBook
        9 7 8 0 4 4 4 6 0 1 2 4 7
      Interaction of Translational and Transcriptional Controls in the Regulation of Gene Expression presents the proceedings of the Fogarty International Conference on Translational/Transc... Regulation of Gene Expression, held at the National Institutes of Health in Bethesda, Maryland, on April 7-9, 1982. Speakers discussed the molecular strategies at work during the modulation of gene expression following transcriptional initiation. They also discussed recent developments in a number of key areas in which transcriptional and translational components interact. Organized into five sections encompassing 36 chapters, this volume explores both prokaryotic and eukaryotic systems, as well as structure-function correlations. It begins with an overview of translational/transc... controls in prokaryotes, the regulation of gene expression by transcription termination and RNA processing, and the structure and expression of initiation factor genes. It then examines the effect of the codon context on translational fidelity, including mistranslation of messenger RNA; protein synthesis for the construction of cell architecture; regulation of initiation factor activity; and translational regulation in cells. This book is a valuable resource for Fogarty International Scholars who want to broaden their knowledge and contribute their expertise to the National Institutes of Health community.

    • Gap Junctions

      • 1st Edition
      • December 2, 2012
      • J.E. Hall + 2 more
      • English
      • eBook
        9 7 8 0 4 4 4 5 9 9 8 4 1
      Gap junctions are present in nearly all tissues, regardless of their embronic origin and have long been of great interest to scientists from many different disciplines. The international meeting on which this book is based brought together 157 scientists from 12 countries and almost as many scientific disciplines. The papers presented at the meeting were reviewed and updated prior to publication in this book. The seven parts of the book progress from general topics to the more specific ones (role of gap junctions in various tissues, regulation and biochemistry, and cancer).

    • Molecular Action of Toxins and Viruses

      • 1st Edition
      • Volume 2
      • December 2, 2012
      • P. Cohen + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 7 1 8 5
      • eBook
        9 7 8 0 4 4 4 6 0 0 9 7 4
      Molecular Action of Toxins and Viruses investigates the molecular action of bacterial toxins and viruses and its striking similarity to the mechanisms by which many neural and hormonal stimuli control normal cell functions. Topics covered include the biological activity of diphteria toxin; the role of cholera toxin in the regulation of hormone-sensitive adenylate cyclase; toxic lectins and related proteins; and bacterial cytolysins (membrane-damaging toxins). Comprised of nine chapters, this volume begins with a discussion on the biosynthesis and biological activity of diphtheria toxin, toxin-resistant mutant cells, and the entry of toxin into cells and fragment A in the cytoplasm of living cells. The reader is then systematically introduced to the use of cholera toxin as a probe to study the regulation and interaction of adenylate cyclase components; the toxic action of lectins and related proteins such as abrin, ricin, and modeccin; and the ability of bacterial cytolysins to damage cell membranes. The remaining chapters focus on the mechanism of action of colicin E2, colicin E3, and cloacin DF13; similarities in the action of different bacterial toxins; the role of cell membranes in infection with bacterial viruses and colicins; and the life cycle and infection mechanisms of bacteriophage T4. The book concludes with an analysis of the involvement of protein kinases in viral transformation. This monograph will be of interest to students, practitioners, and researchers in fields ranging from molecular biology and biochemistry to cell biology, bacteriology, and physiology.

    • RNA: Catalysis, Splicing, Evolution

      • 1st Edition
      • December 2, 2012
      • M. Belfort + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 6 3 2 4
      • eBook
        9 7 8 0 4 4 4 5 9 9 7 1 1
      The conference on "RNA: Catalysis, Splicing, Evolution" brought together a unique assembly of scientific leaders in this currently very important field. Two participants of this Conference, Drs. T.R. Cech and S. Altman, were just awarded the 1989 Nobel prize in chemistry, which attests to the timeliness of this volume. The critical reviews authored by these two prominent scientists are included. For those scientists with roots in this field, who do not subscribe to GENE, this is an excellent opportunity to obtain a masterly collection of papers. All the original papers and reviews have undergone the rigorous peer review of the journal "Gene".

    • Selected Topics in the History of Biochemistry. Personal Recollections. Part III

      • 1st Edition
      • Volume 37
      • December 2, 2012
      • G. Semenza + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 5 2 2 8
      • eBook
        9 7 8 0 4 4 4 5 9 8 1 2 7
      As in Volumes 35 and 36, the chapters in this new volume complement, with personal recollections, the History of Biochemistry that was covered in the Comprehensive Biochemistry Series, Volumes 30-33 by M. Florkin and Volume 34A by P. Laszlo. The biographical and autobiographical chapters will convey to the reader a lively, albeit at times subjective, view of the scientific and social environment in which the authors have worked, resulting in new concepts and theories on the biological sciences.

    • Selected Topics in the History of Biochemistry

      • 1st Edition
      • Volume 35
      • December 2, 2012
      • G. Semenza
      • English
      • eBook
        9 7 8 0 4 4 4 5 9 8 2 0 2
      Selected Topics in the History of Biochemistry: Personal Recollections, I presents selected topics in the history of biochemistry based on the authors' personal recollections. These topics range from the isolation of Cori ester and the discovery of sugar nucleotides to the work of Frederick Gowland Hopkins (1861-1947). Ion-coupled membrane processes are also discussed, along with fructose and fructose-2,6-bisphos... well as lysosomes and glycogen. Comprised of 12 chapters, this volume begins with the discovery of Cori ester and the concept of phosphorolysis before turning to the discovery of sugar nucleotides and research on ion-coupled membrane processes. The reader is then introduced to studies of fructose, fructose-2,6-bisphos... lysosomes, and glycogen; the contributions of Frederick Gowland Hopkins in biochemistry; and a short autobiography of Juda Hirsch Quastel, with emphasis on his research work on the concept of active centers as a possible explanation of enzyme action and his investigation of the effects of malonic acid and substituted malonic acids on bacterial dehydrogenases. The remaining chapters focus on a biochemist's approach to autopharmacology; the early development of modern protein chemistry in Uppsala, Sweden; and the biographies of two Russian scientists, A. N. Bach and Sergei E. Severin. This monograph will be of interest to students, practitioners, and researchers in the field of biochemistry.

    • Selected Topics in the History of Biochemistry

      • 1st Edition
      • Volume 36
      • December 2, 2012
      • G. Semenza
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 5 2 9 7
      • eBook
        9 7 8 0 4 4 4 5 9 8 2 1 9
      One of the most exciting developments in biological sciences has been their merging with chemistry and physics resulting in the new disciplines of biochemistry, biophysics and molecular biology. As the developments of these new disciplines has been so rapid many of the key discoveries have occurred within the life-time of a number of prominent scientists in the field. The chapters in this and in future volumes are meant to complement with personal recollections by these scientists, the History of Biochemistry in this series (vols. 30-33 by M. Florkin and Vol. 34 by P. Laszlo). These bibliographic and autobiographic chapters convey to the reader lively, albeit at times subjective, views on both the scientific and social environments of the authors. The editor cosidered it presumptuous to give the authors narrow guidelines or to suggest changes in the chapters he received. The contributions assembled in this volume will convey the flavour of each author's particular personality.

    • Lipoprotein Kinetics and Modeling

      • 1st Edition
      • December 2, 2012
      • Mones Berman
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 4 4 6 0
      • eBook
        9 7 8 0 3 2 3 1 4 7 6 4 4
      Lipoprotein Kinetics and Modeling contains some of the papers presented at a conference on the analysis and modeling of lipoprotein kinetic data held in Phoenix, Arizona. Contributions from both theorists and experimentalists who attended the conference focus on the developments in the use of mathematical modeling in analyzing the lipoprotein kinetics. The conference highlights the role of kinetic modeling in elucidating the dynamic processes involved in lipoprotein metabolism, the result of improper data analysis that can lead to erroneous physiological interpretations, and the emerging complexities in the lipoprotein system. Organized into six sections comprised of 37 chapters, this book begins with an overview of the theory and applications of kinetic analysis and modeling to lipoproteins. It then discusses the role of kinetic modeling in physiology, the kinetics of apoprotein B in humans, the use of kinetics in investigating the metabolism of very low and intermediate-density lipoproteins, and the models of plasma lipoprotein triglyceride kinetics. It explains the cholesterol kinetics and modeling, the kinetics of high density lipoprotein metabolism in humans, and various techniques for the analysis and modeling of lipoprotein kinetic data such as KABIS (kinetic analysis by interactive simulation) and CONSAM (conversational version of the SAAM modeling program). This book will be of interest to biologists, physiologists, clinical researchers and experts in computer technology and mathematics.

    • The Physiology of Insecta V5

      • 2nd Edition
      • December 2, 2012
      • Morris Rockstein
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 8 0 0 5
      • Hardback
        9 7 8 0 1 2 5 9 1 6 0 5 9
      • eBook
        9 7 8 0 3 2 3 1 6 1 4 1 1
      The Physiology of Insecta, Second Edition, Volume V, is part of a multivolume treatise that brings together the known facts, the controversial material, and the many unresolved and unsettled problems of insect physiology. It features chapters written by the outstanding workers in each of a wide range of insect function areas. It is designed to meet a manifest need, which has arisen from the phenomenal increase in research activity on insects, for an authoritative, comprehensive reference work in insect physiology. The book begins with a discussion of insect nutrition. This is followed by separate chapters on the physiology of digestion and absorption; the factors affecting insect heart rates; the electrical properties of the insect heart; and the hemocytes of insects. Subsequent chapters cover the physiological role and the adaptive significance of the main biochemical constituents of insect hemolymph; salt and water balance in insects; defense reactions in insects; and microsomal mixed-function oxidases.

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