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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Basic Biotechniques for Bioprocess and Bioentrepreneurship

      • 1st Edition
      • February 3, 2023
      • Arvind Kumar Bhatt + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 1 0 9 8
      • eBook
        9 7 8 0 1 2 8 1 6 1 1 0 4
      Basic Biotechniques for Bioprocess and Bioentrepreneurship deals with the entire field of industrial biotechnology, starting from the basic laboratory techniques to scale-up, process development, demonstration, and finally its commercialization. The book compiles currently scattered materials on this topic and updates this information based on practical experience and requirements. The book will be an ideal source for new entrepreneurs who wish to start their own commercial units.

    • Novel Methods and Pathways in Cancer Glycobiology Research

      • 1st Edition
      • Volume 157
      • February 2, 2023
      • English
      • Hardback
        9 7 8 0 3 2 3 9 9 1 7 7 3
      • eBook
        9 7 8 0 3 2 3 9 9 1 7 8 0
      Cancer glycobiology is a blazing hot area of cancer research with aberrant post-translational glycosylations on lipids and proteins considered critical for cancer development and metastasis. The NIH/NCI Alliance of Glycobiologists for Cancer Research is a consortium of (10) tumor glycobiology laboratories funded to investigate how cancer-associated glycans (CAG) impact the development and metastasis of cancer. The hope of this momentous effort is to discover CAGs for use as novel biomarkers to detect early-stage cancer or its aggressive behavior or, alternatively, as novel molecular targets with the promise of a curative approach to cancer therapy. The mission of the ‘Alliance’ is to study structure and function of CAGs in cancer development and to provide clinically useful biomarkers for detecting cancer early or the potential of metastasis. This charge has stimulated extensive collaborations across US and International institutions to accelerate discovery of glycan-based biomarkers to the forefront of NCI's efforts to diagnose early-stage cancer and provide curative anti-cancer therapies. The main goals of these research efforts are: 1. To identify and study how cancer-associated glycans functionally impact cancer growth and metastasis2. To identify cancer-associated glycans that can serve as biomarkers for the detection or progression of cancer3. To develop cancer-associated glycans as novel therapeutic targets for the treatment and cure of cancer This volume consists of (9) chapters, one from each funded laboratory, that reviews new methods and mechanisms highlighting glycoconjugates and their roles as cancer biomarkers and/or anti-cancer therapeutic targets.

    • Oxidative Stress Responses in Plants

      • 1st Edition
      • Volume 105
      • January 31, 2023
      • English
      • Hardback
        9 7 8 0 3 2 3 9 1 3 7 4 4
      • eBook
        9 7 8 0 3 2 3 9 1 3 7 5 1
      Oxidative Stress Response in Plants, Volume 105 covers environmental stress conditions and the accumulation of reactive oxygen species (ROS). During many stress conditions such as salt, drought, heat, and pathogen infection, changes in metabolic fluxes and alterations in enzymatic activities result in the accumulation of ROS, a major contributor to loss of growth and productivity. High levels of ROS can lead to oxidative stress which damages proteins and DNA, ultimately resulting in plant cell death. This volume provides comprehensive insights into ROS biology in plants, with a focus on plant growth and development, plant defense responses, and plant acclimation to challenging environments. On the other hand, ROS evolves into potent signaling molecules that play crucial roles in abiotic and biotic stress sensing, integration of different environmental signals, and activation of stress-response networks, thereby contributing to the establishment of improved stress resilience.

    • Radiation Oncology and Radiotherapy Part B

      • 1st Edition
      • Volume 174
      • January 31, 2023
      • English
      • Hardback
        9 7 8 0 3 2 3 8 9 9 4 7 5
      • eBook
        9 7 8 0 3 2 3 8 9 9 4 8 2
      Radiation Oncology and Radiotherapy, Part B, Volume 174 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics including CT-assisted focal irradiation of tumors in mice, Methods to preserve correct dosimetry in small animal irradiators, Monitoring TGFbeta signaling in irradiated tumors, Cytofluorometric characterization of the lymphoid compartment of irradiated tumors, Cytofluorometric characterization of the myeloid compartment of irradiated tumors, Mass cytometry to characterize the immune infiltrate of irradiated tumors, Characterization of the immune infiltrate in irradiated mouse tumor by multiplex immunofluorescence, and much more. Other chapters cover Methods to study FOXP3+CD8+ cells in irradiated bone metastases, Luminex-based characterization of cytokine signaling by irradiated tumors, Explant-based assessment of anticancer immunity in irradiated tumors, Pipeline to characterize the TCR repertoire of irradiated tumors, Pipeline to identify tumor neoantigens exposed by radiation, and more.

    • Overcoming Resistance to EGFR Inhibitors in EGFR-Mutant NSCLC

      • 1st Edition
      • Volume 19
      • January 30, 2023
      • Anthony Faber
      • English
      • Hardback
        9 7 8 0 1 2 8 2 2 8 3 3 3
      • eBook
        9 7 8 0 1 2 8 2 2 8 3 4 0
      Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC presents updated information on how EGFR mutant lung cancers evolve to evade EGFR inhibitors, clinical strategies that identify these mechanisms, and how to implement newer therapeutic strategies to combat resistance and improve patient survival. As resistance to EGFR inhibitors is often through re-activation of MEK/ERK and PI3K pathways, or through loss of cell death responses, there is much overlap with resistance to targeted therapies in other paradigms, such as BRAF inhibitors in BRAF mutant melanoma, and HER2 inhibitors in HER2 amplified breast cancer. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field who are interested in promising treatments for lung cancer.

    • Transcription and Translation in Health and Disease

      • 1st Edition
      • January 30, 2023
      • Manoj Garg + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 5 2 1 4
      • eBook
        9 7 8 0 3 2 3 9 9 5 2 2 1
      Transcription and Translation in Health and Disease provides a detailed overview of the regulators underlying transcription and translation in relation to a variety of human diseases and disorders. Beginning with an introduction into the current perspectives relating to these processes in human disease, the book expands to focus on specific mechanisms underlying conditions such as arthritis, cancer, neurological disorders, diabetes and cardiovascular disease. This book considers RNA processing and related mechanisms in eukaryotes including RNA splicing, RNA binding proteins, RNA interference, microRNAs, RNA editing, transcription factors, RNAi screening, CRISPR activation, CRISPR-Cas9 interference, and post-translational modifications. It provides a structured and detailed overview of the various regulators underlying molecular processes and their impact on health and disease, equipping readers with the necessary knowledge for further investigation in the areas of treatment and therapeutic intervention.

    • Joint and Bone

      • 1st Edition
      • January 30, 2023
      • Deming Jiang + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 9 3 8 8
      • eBook
        9 7 8 0 3 2 3 9 8 3 3 0 3
      Joint and Bone: From Bench to Bedside, Volume Three, the latest release in the Stem Cell Innovation in Health and Disease series, is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. This new volume addresses the molecular players underlying iPSC formation, maintenance, and expansion and differentiation, bringing chapters that describe cutting-edge research for understanding stem cell functions in joint and bone diseases, and for developing methods to bring stem cells from bench to bedside. Each chapter includes insights ranging from the use of mouse and human organoid cultures, genetic editing in vitro and in vivo, and human iPSCs to study stem cell functions and model joint and bone diseases.

    • Human Histology

      • 1st Edition
      • January 28, 2023
      • Bertalan Dudas
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 8 9 1 6
      • eBook
        9 7 8 0 3 2 3 9 8 4 9 6 6
      Visually engaging and easy to use, Human Histology: A Text and Atlas for Physicians and Scientists covers the normal histology of every organ in the human body. This book presents full-page high-definition photomicrographs for organs and tissues, followed by a compact and simple-to-read description of the structures identified on the micrographs, offering a clear, visual understanding of this complex subject. With over 300 outstanding images, this reference is an invaluable resource for every clinical researcher and pathologist in need of easily accessible, relatively simple but detailed enough information on normal histology of different organs systems. Due to its compact, but detailed layout, the volume is an excellent tool for medical board review and can be recommended for medical students and histology course directors.

    • Biochemical Pathways and Environmental Responses in Plants: Part B

      • 1st Edition
      • Volume 680
      • January 27, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 5 8 4 7
      • eBook
        9 7 8 0 4 4 3 1 8 5 8 5 4
      Biochemical Pathways and Environmental Responses in Plants, Part B, Volume 682 in the Methods in Enzymology series, highlights advances in the field with this new volume presenting chapters on MIE 681/682: Biochemical pathways and environmental responses in plants, Structure, function, and engineering of plant polyketide synthases, A sensitive LC-MS/MS assay for enzymatic characterization of methylthioalkylmalat... synthase involved in glucosinolate side-chain elongation, Assaying formate-tetrahydrofo... ligase with monoglutamylated and polyglutamylated substrates using a fluorescence-HPLC based assay, An Approach to Nearest Neighbor Analysis of Pigmented Protein Complexes by Using Chemical Crosslinking in Combination with Mass Spectrometry, Biochemical characterization of plant aromatic aminotransferases, and much more. Other chapters focus on Functional Analysis of Phosphoethanolamine N-methyltransferase (PMT) in Plants and Parasites, A structure-guided computational screening approach for predicting plant enzyme-metabolite interactions, Plant metacaspase: an example of microcrystal structure determination and analysis, Biocatalytic system for comparative assessment of functional association of cytochrome P450 monooxygenases with their redox partners, Dirigent Protein Family Function and Structure, and more.

    • Antioxidants

      • 1st Edition
      • Volume 121
      • January 25, 2023
      • Gerald Litwack
      • English
      • Hardback
        9 7 8 0 4 4 3 1 5 7 6 8 4
      • eBook
        9 7 8 0 4 4 3 1 5 7 6 9 1
      Antioxidants, Volume 121 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

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