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Radiation Oncology and Radiotherapy Part B

  • 1st Edition, Volume 174 - January 31, 2023
  • Latest edition
  • Editors: Ai Sato, Jeffrey Kraynak, Ariel E. Marciscano, Lorenzo Galluzzi
  • Language: English

Radiation Oncology and Radiotherapy, Part B, Volume 174 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesti… Read more

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Description

Radiation Oncology and Radiotherapy, Part B, Volume 174 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics including CT-assisted focal irradiation of tumors in mice, Methods to preserve correct dosimetry in small animal irradiators, Monitoring TGFbeta signaling in irradiated tumors, Cytofluorometric characterization of the lymphoid compartment of irradiated tumors, Cytofluorometric characterization of the myeloid compartment of irradiated tumors, Mass cytometry to characterize the immune infiltrate of irradiated tumors, Characterization of the immune infiltrate in irradiated mouse tumor by multiplex immunofluorescence, and much more.

Other chapters cover Methods to study FOXP3+CD8+ cells in irradiated bone metastases, Luminex-based characterization of cytokine signaling by irradiated tumors, Explant-based assessment of anticancer immunity in irradiated tumors, Pipeline to characterize the TCR repertoire of irradiated tumors, Pipeline to identify tumor neoantigens exposed by radiation, and more.

Key features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Methods in Cell Biology series
  • Includes the latest information on the topic of development, characterization and applications in CAR T Cells

Readership

Academic, researchers, government and industrial sectors

Table of contents

  1. Flow cytometry-assisted quantification of immune cells infiltrating irradiated tumors in mice
    Sara Labiano, Irantzu Serrano-Mendioroz, and María Esperanza Rodriguez-Ruiz
  2. Cytofluorometric characterization of the myeloid compartment of irradiated mouse tumors
    Marine Gerbé De Thoré, Lydia Meziani, Eric Deutsch, and Michele Mondini
  3. Mass cytometry to characterize the immune lung cancer microenvironment
    Ti Badri, Iñaki Eguren-Santamaria, Eva Fernandez-Pierola, and Miguel F. Sanmamed
  4. Characterization of the immune infiltrate in mouse tissue by multiplex immunofluorescence
    Teresa Marafioti, Maria D. Lozano, and Carlos E. de Andrea
  5. Ex vivo analysis of radiation effects on tumor infiltrating immune cells using tumor explants
    Aanchal Preet Kaur, Gwen Kramer, Marka R. Crittenden, and Michael J. Gough
  6. Assessment of immunological memory formation in vivo
    Shuai Zhang, Liwei Zhao, Hui Chen, Guido Kroemer, Peng Liu, and Oliver Kepp
  7. MorphoMacro for in vivo and ex vivo quantitative morphometric analysis of microglia
    Pedro Melo, Mariana S. Silveira, Inês Mendes-Pinto, and João B. Relvas
  8. Quantitative assessment of mitophagy in irradiated cancer cells
    Emma Guilbaud, Sheila Spada, Norma Bloy, Claudia Galassi, Ai Sato, Carlos Jiménez-Cortegana, Artur Aretz, Aitziber Buqué, Takahiro Yamazaki, Sandra Demaria, and Lorenzo Galluzzi
  9. Quantification of beta-galactosidase activity as a marker of radiation-driven cellular senescence
    Vanessa Klapp, Norma Bloy, Giulia Petroni, and Mara De Martino
  10. A simple method to assess clonogenic survival of irradiated cancer cells
    Irantzu Serrano-Mendioroz, Eneko Garate-Soraluze, and María Esperanza Rodriguez-Ruiz
  11. Clonogenic assay to measure bystander cytotoxicity of targeted alpha-particle therapy
    Julie Constanzo, Clara Diaz Garcia-Prada, and Jean-Pierre Pouget

Product details

  • Edition: 1
  • Latest edition
  • Volume: 174
  • Published: February 21, 2023
  • Language: English

About the editors

AS

Ai Sato

Ai Sato is a research specialist at Stich Radiation Oncology, New York, NY, USA
Affiliations and expertise
Stich Radiation Oncology, New York, NY, USA

JK

Jeffrey Kraynak

Jeffrey Kraynak is a research laboratory specialist at Stich Radiation Oncology, New York, NY, USA.
Affiliations and expertise
research laboratory specialist at Stich Radiation Oncology, New York, NY, USA.

AM

Ariel E. Marciscano

Dr. Ariel E. Marciscano is an assistant professor of Radiation Oncology at Weill Cornell Medical College.
Affiliations and expertise
Assistant Professor of Radiation Oncology, Weill Cornell Medical College

LG

Lorenzo Galluzzi

Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology. Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.
Affiliations and expertise
Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA

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