Antioxidants
- 1st Edition, Volume 121 - January 25, 2023
- Imprint: Academic Press
- Editor: Gerald Litwack
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 5 7 6 8 - 4
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 5 7 6 9 - 1
Antioxidants, Volume 121 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an intern… Read more
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Request a sales quoteAntioxidants, Volume 121 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the Vitamins and Hormones series
- Updated release includes the latest information on Antioxidants
Undergraduates, graduates, academics, and researchers in the field of vitamins and hormones
- Cover image
- Title page
- Table of Contents
- Copyright
- Former Editors
- Contributors
- About the editor
- Preface
- Chapter One: In silico study of natural antioxidants
- Abstract
- 1: Antioxidants
- 2: Natural antioxidants
- 3: Computer assisted study of natural antioxidant activities
- 4: Conclusion and future direction
- References
- Chapter Two: Hydrogen peroxide detoxification through the peroxiredoxin/thioredoxin antioxidant system: A look at the pancreatic β-cell oxidant defense
- Abstract
- 1: The many roles of ROS in mammalian cells
- 2: Thioredoxin and thioredoxin reductase
- 3: Catalytic mechanisms and isoforms of peroxiredoxins
- 4: Relevance to human disease: Roles of thioredoxin/peroxiredoxin in protecting pancreatic β-cells from oxidative damage
- 5: Peroxiredoxin-mediated hydrogen peroxide signaling
- 6: Hydrogen peroxide signaling and β-cell function
- Funding
- References
- Chapter Three: Molecular docking approaches and its significance in assessing the antioxidant properties in different compounds
- Abstract
- 1: Introduction
- 2: Molecular docking techniques
- 3: Docking strategies based on the flexibility and rigidity of interacting components
- 4: Docking studies to evaluate antioxidant activity of compounds
- 5: Future scope of the work
- 6: Conclusion
- References
- Chapter Four: Scavengome of an antioxidant
- Abstract
- 1: Antioxidants and their mechanism of action: Introduction of the scavengome concept
- 2: Biomimetic oxidative chemistry: Exploring the scavengome
- 3: Oxidative transformations of selected antioxidants
- 4: Drug discovery value of the chemical metabolite space of I–IV
- 5: Summary
- Acknowledgments
- References
- Chapter Five: The antioxidant glutathione
- Abstract
- 1: Introduction
- 2: Glutathione
- 3: The many roles of glutathione as an antioxidant
- 4: S-glutathionylation and role of glutathione in redox regulation
- 5: Conclusions and future directions
- Acknowledgments
- References
- Chapter Six: Beneficial antioxidant effects of Coenzyme Q10 on reproduction
- Abstract
- 1: Introduction
- 2: CoQ10 supplementation promotes female reproductive health
- 3: Potential pharmacologic interactions of CoQ10 supplementation
- 4: Conclusion
- References
- Chapter Seven: Antioxidants affect endoplasmic reticulum stress-related diseases
- Abstract
- 1: The endoplasmic reticulum (ER)
- 2: ER stress and oxidative stress crosstalk
- 3: Antioxidants and regulation of the UPR
- 4: Antioxidants and ER stress-related diseases
- 5: Concluding remarks and future directions
- Acknowledgments
- References
- Chapter Eight: Hormone-linked redox status and its modulation by antioxidants
- Abstract
- 1: Introduction
- 2: Hormones, redox status, and antioxidant defense system
- 3: Methods to measure oxidative stress markers and their limitations
- 4: Hormones triggering oxidative stress and the role of antioxidant supplements
- 5: Hormones exhibiting antioxidant properties
- 6: Conclusion
- Acknowledgments
- References
- Chapter Nine: Ascorbic acid as antioxidant
- Abstract
- 1: Introduction
- 2: Chemical structure and bioavailability
- 3: Antioxidant properties
- 4: Ascorbic acid and oxidative modifications
- 5: Ascorbic acid cooperation with other antioxidants
- 6: Summary
- References
- Chapter Ten: Free radicals, antioxidants, nuclear factor-E2-related factor-2 and liver damage
- Abstract
- 1: Liver disease etiology
- 2: Reactive oxygen species (ROS) in liver health and disease
- 3: Antioxidants in liver health and disease
- 4: Oxidative stress, Nrf2 and liver fibrosis
- 5: Conclusions and future directions
- Acknowledgments
- Funding
- References
- Chapter Eleven: Mechanisms of action of vitamin D in delaying aging and preventing disease by inhibiting oxidative stress
- Abstract
- 1: Introduction
- 2: The effect of 1,25-dihydroxyvitamin D deficiency and 1,25-dihydroxyvitamin D supplementation on aging and age-related diseases and on oxidative stress parameters in studies in animals in vivo and in vitro
- 3: Mechanisms of action of 1,25-dihydroxyvitamin D in reducing oxidative stress
- 4: The effect of vitamin D supplementation on aging and age-related diseases and on oxidative stress parameters in humans
- 5: Controversies of the use of vitamin D supplementation in humans to reduce its anti-oxidant effect and ameliorate age-related disease
- Acknowledgments
- References
- Chapter Twelve: Antioxidant conjugated metal complexes and their medicinal applications
- Abstract
- 1: Introduction
- 2: Antioxidant conjugated metal complexes
- 3: Conclusions
- Acknowledgments
- References
- Chapter Thirteen: Natural–product–inspired bioactive alkaloids agglomerated with potential antioxidant activity: Recent advancements on structure-activity relationship studies and future perspectives
- Abstract
- 1: Introduction
- 2: Mechanism of antioxidant potential and its evaluation methods
- 3: Structure-activity relationship studies of natural bioactive alkaloids agglomerated with potential antioxidant property
- 4: Application of antioxidant potential of alkaloids (Table 1)
- 5: Summary
- 6: Conclusion
- 7: Future perspectives
- Acknowledgments
- Declarations
- References
- Further reading
- Chapter Fourteen: Antioxidants: Structure–activity of plant polyphenolics
- Abstract
- 1: Introduction to polyphenolics
- 2: Polyphenolics as antioxidants
- 3: Potent key targets behind antioxidant therapies
- 4: Structure–activity of plant metabolites
- 5: Conclusions
- Acknowledgments
- References
- Chapter Fifteen: Protein l-isoAspartyl Methyltransferase (PIMT) and antioxidants in plants
- Abstract
- 1: Introduction
- 2: Abiotic stress and reactive oxygen species
- 3: Antioxidants in plants
- 4: Protein l-isoAspartyl Methyltransferases
- 5: Role of PIMT in plants
- 6: PIMT and antioxidants
- 7: Identification of isoAsp susceptible proteins
- 8: Conclusion
- References
- Edition: 1
- Volume: 121
- Published: January 25, 2023
- No. of pages (Hardback): 452
- No. of pages (eBook): 452
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780443157684
- eBook ISBN: 9780443157691
GL
Gerald Litwack
Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)
Affiliations and expertise
Emeritus Founding Chair and Professor, Geisinger Commonwealth School of Medicine, United States
Emeritus Professor, Rutgers University, United StatesRead Antioxidants on ScienceDirect