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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Cases in Laboratory Genetics and Genomics (LGG) Practice

      • 1st Edition
      • June 5, 2023
      • Xia Li
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 6 2 2 8
      • eBook
        9 7 8 0 3 2 3 9 9 6 2 3 5
      Cases in Laboratory Genetics and Genomics (LGG) Practice instructs readers in the lab-based diagnosis of genetic conditions, including inborn and acquired disorders using cytogenetics and molecular genetics technologies. This entirely case-based book covers a wide range of genetic cases, from prenatal to postnatal and oncology genetic disorders which lab professionals and geneticists encounter daily in the diagnostic field. Each disorder discussed includes a section on clinical background, clinical indication, tests ordered, laboratory tests performed, test results, results with interpretations, future testing and recommendations, and references. The book will help lab professionals understand and navigate clinical cases using an integrative approach, and thoroughly understand the methodologies and interpretations involved in high complexity genetic testing.

    • Ozone Pollution and Plant Health: Understanding the Impacts and Solutions for Sustainable Agriculture

      • 1st Edition
      • Volume 108
      • June 1, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 3 3 5 0 3
      • eBook
        9 7 8 0 4 4 3 1 3 3 5 1 0
      Advances in Botanical Research Volume 108: Ozone Pollution and Plant Health: Understanding the Impacts and Solutions for Sustainable Agriculture provides a comprehensive overview of the harmful effects of tropospheric ozone (O3) pollution on crop productivity, with a focus on how it is measured and modeled under climate change scenarios. The book discusses the sources of O3 pollution, including anthropogenic precursor gases, and how O3 exposure can impair photosynthesis, reduce gas exchange, induce early leaf senescence, and hamper growth in natural vegetation and crops. The book highlights how O3 interacts with plant physiology and metabolism, including through the activation of signal transduction pathways, changes in phytohormone signaling, and modulation of reactive oxygen species (ROS) generation and signaling. The book also explores the experimental and modeling methods used to assess the effects of O3 on crops, with a focus on studies conducted in Asia. The book emphasizes the importance of understanding the implications of ozone pollution for ensuring food security and protecting human and environmental health and suggests strategies such as using ozone-resistant cultivars of plants and crops. Additionally, the book discusses the broader context of air pollution and its impact on crop productivity, including the effects of other air pollutants on plants and crops and the need for mitigation strategies and policies to address agricultural losses. This book is essential reading for early-career researchers, sustainable agriculture practitioners, and policymakers interested in understanding the complex interactions between ozone pollution and plant productivity and finding solutions to mitigate the detrimental effects of ozone pollution on crops in a changing climate.

    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 114
      • June 1, 2023
      • Gregory S. Makowski
      • English
      • Hardback
        9 7 8 0 4 4 3 1 9 2 8 8 3
      • eBook
        9 7 8 0 4 4 3 1 9 2 8 9 0
      Advances in Clinical Chemistry, Volume 114, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New sections in the updated release include Growth differentiation factor 15 (GDF-15) in kidney diseases, Alkaptonuria - past, present and future, Alcohol Consumption and Nutritional Biomarkers in Early-Stage Alcohol-Associated Liver Disease, Advances in Liquid Biopsy–Based Markers in NSCLC, D-dimer testing: a narrative review, Evolving Markers in Amyotrophic Lateral Sclerosis, and more.

    • Pancreatic Cancer: Basic Mechanisms and Therapies

      • 1st Edition
      • Volume 159
      • May 31, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 3 3 5 4 1
      • eBook
        9 7 8 0 4 4 3 1 3 3 5 5 8
      Pancreatic Cancer: Basic Mechanisms and Therapies, Volume 159 in the Advances in Cancer Research, presents the latest release in this ongoing, well-regarded serial with invaluable information on the exciting and fast-moving field of cancer research. Pancreatic cancer (PC) is the third leading cause of cancer-related deaths in the United States. Greater than 90% PCs are Pancreatic ductal adenocarcinomas (PDAC) which have a dismal estimated 5-year overall survival of only 11%. PDAC is predicted to become the second leading cause of mortality in the United States by 2030. In the clinic, the PDAC patients often present with incurable disease at the time of first diagnosis. This cancer is particularly lethal because of its propensity to spread quickly to distant organs including the lymphatic system. PDAC metastasis occurs shortly after tumor initiation and is caused by a complex interaction between autonomous tumor cells and cellular elements of the tumor microenvironment. Although PDAC remains a challenging disease to treat and a leading cause of cancer-related deaths, progress is being made in disease etiology and pathogenesis, and intensive research is focused on developing optimal treatment approaches for patients. Considering the continuous progress being made in understanding PDAC pathogenesis and designing new therapies, it was considered timely to develop an up-to-date thematic issue of Advances in Cancer Research (ACR) focused on PDAC. In this thematic issue, we have included ten review articles by experts that cover cancer disparities, PDAC pathobiology, the roles of the tumor microenvironment, tumor heterogeneity, PC stem cells, genetic and signaling events critical for PDAC pathogenesis, Immunotherapy and chemoresistance in PDAC, and different PDAC mouse models. This special issue highlights recent research progress in PDAC, which bridges the gap between basic and clinical research.

    • Mitochondria and Bacterial Pathogens - Part B

      • 1st Edition
      • Volume 377
      • May 31, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 9 1 2 3 7
      • eBook
        9 7 8 0 4 4 3 1 9 1 2 4 4
      Mitochondria and Bacterial Pathogens, Part B, Volume 375 discusses different pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells. Chapters in this new release include Interaction between host cell mitochondria and Coxiella Burnetii, Control of mitochondrial functions by Pseudomonas aeruginosa in cystic fibrosis, Mitochondrial and bacterial ATP synthase: Structural similarities and divergences to exploit in the battle against M. tuberculosis, Role of mitochondria in the enteropathogenic Escherichia coli disease, Mitochondria dynamics and antibiotic resistance, and more.

    • Environmental Contaminants and Endocrine Health

      • 1st Edition
      • May 30, 2023
      • Oliana Carnevali + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 4 4 6 4 7
      • eBook
        9 7 8 0 3 2 3 8 5 9 3 2 5
      Environmental Contaminants and Endocrine Health focuses specifically on contaminants with hormonal disrupting activities. The book provides insights into the multiple effects of endocrine-disrupting chemicals (EDCs) and their mechanism of action (MoA) on metabolism, reproduction and the multiple physiological roles of the endocannabinoid system which has recently been indicated as new target. The content systematically covers EDC sources and effects, EDCs as sources of disease and health impairment in laboratory models, EDCs as the cause of disease and health impairment in humans and wild species, and the removal of hazardous pollutants from wastewaters to highlight intervention, mitigation and adaptation for reduced threat. This content will be a foundational resource for academic and research staff in endocrinology and hormone toxicology as well as for professors, researchers and students in these areas.

    • Accelerating Strategic Changes for Digital Transformation in the Healthcare Industry

      • 1st Edition
      • May 30, 2023
      • Patricia Ordonez de Pablos + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 2 9 9 3
      • eBook
        9 7 8 0 4 4 3 1 5 3 0 0 6
      Accelerating Strategic Changes for Digital Transformation in the Healthcare Industry discusses innovative conceptual frameworks, tools and solutions to tackle the challenges of mitigating major disruption caused by COVID-19 in the healthcare sector and society. It emphasizes global case studies and empirical studies, providing a comprehensive view of best lessons on digital tools to manage the health crisis. The book focuses on the role of advances in digital and collaborative technologies to offer rapid and effective tools for better health solutions for new and emerging health problems. Researchers, students, policymakers and members of the biomedical and medical fields will find this information invaluable. Specially, it pays attention to how information technologies help us in the current global health emergency and the coronavirus epidemic response, gaining more understanding of the new coronavirus and helping to contain the outbreak. In addition, it explores how these new tools and digital health solutions can support the economic and social recovery in the post-pandemic world.

    • Aptamers for Food Applications

      • 1st Edition
      • May 27, 2023
      • Yiyang Dong
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 9 0 3 6
      • eBook
        9 7 8 0 3 2 3 9 8 5 1 4 7
      Aptamers for Food Applications: Safety, Authenticity, and Integrity outlines the main applications of aptamers to ensure food safety, quality and compliance that are crucial for food science, public health and human sustainability. Aptamers or aptamer-based analytical devices are comprehensively summarized to tackle various food contamination or food adulteration problems. Topics covered in this book include aptamers for foodborne microbial pathogens, pesticide or veterinary drug residues, heavy metals, biotoxins, abused food additives, illegal food adulterants, POPs, GMOs, food allergens and food contact material migrants. It is therefore of interest for not only analytical investigators and food safety inspectors, but also regulatory practitioners and risk assessors in various food science and research fields.

    • Stem Cell Laboratory Techniques

      • 1st Edition
      • May 27, 2023
      • Suresh Kumar Kailasa + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 7 2 9 8
      • eBook
        9 7 8 0 1 2 8 2 3 7 3 0 4
      Stem Cell Laboratory Techniques: A Guide for Researchers and Students introduces the reader to stem cell culture, handling techniques and versatile applications used by researchers. Sections introduce stem cells, including definitions, types and basic use of stem cells in biomedical science research. The book explains laboratory procedures and techniques ranging from the extraction of stem cells from animals, cell seeding and culture, harvest and maintenance of stem cells, stem cell characterization, accurate recording, quality control, and more. In addition, it guides researchers on topics such as transcriptome analysis, proliferation study analysis, and microphysiological study. Final sections cover useful and recent applications in stem cells, such as gene editing techniques and the preparation of stem cells for in vitro study, as well as stem cell lab design and equipment used in the lab. Lastly, human and animal research ethics are discussed.

    • New Experimental Probes for Enzyme Specificity and Mechanism

      • 1st Edition
      • Volume 685
      • May 26, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 5 2 7 6 4
      • eBook
        9 7 8 0 4 4 3 1 5 2 7 7 1
      New Experimental Probes for Enzyme Specificity and Mechanism, Volume 685, the latest release in the Methods of Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics including Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis, New Mechanistic Probes to Identify Novel Substrates for N-Myristoyltransfera... Phosphonate and α Fluorophosphonate Analogues of D Glucose 6 Phosphate as Active-Site Probes of 1L-Myo-Inositol 1 phosphate Synthase, Kinetic Mechanism of Nicotine-Degrading Enzyme Probed by Stopped-Flow Kinetic Analyses, Kinetics and Mechanism for Enzyme-Catalyzed Reactions of Substrate Pieces, and more. Additional chapters cover Kinetics and Mechanism for Reactions of Enzyme Pieces, Evaluation of allostery for the bienzyme assembly of a 3-deoxy-D-arabino heptulosonate-7-phos... synthase and chorismate mutase, Recognition and Catalysis of Reactions of Chiral Substrates by Mandelate Racemase, Innovative and emerging modalities of EGFR kinase inhibitors, Characterization of the Aminoacrylate Intermediate of Tyrosine Phenol-Lyases, and much more.

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