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Advances in Clinical Chemistry
- 1st Edition, Volume 114 - June 1, 2023
- Editor: Gregory S. Makowski
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 9 2 8 8 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 9 2 8 9 - 0
Advances in Clinical Chemistry, Volume 114, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scient… Read more
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Request a sales quoteAdvances in Clinical Chemistry, Volume 114, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New sections in the updated release include Growth differentiation factor 15 (GDF-15) in kidney diseases, Alkaptonuria - past, present and future, Alcohol Consumption and Nutritional Biomarkers in Early-Stage Alcohol-Associated Liver Disease, Advances in Liquid Biopsy–Based Markers in NSCLC, D-dimer testing: a narrative review, Evolving Markers in Amyotrophic Lateral Sclerosis, and more.
- Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science
- Authored by world-renowned clinical laboratory scientists, physicians and research scientists
- Presents the international benchmark for novel analytical approaches in the clinical laboratory
Clinical Laboratory Professionals, Physicians and Research Scientists
- Cover image
- Title page
- Table of Contents
- Advances in CLINICAL CHEMISTRY
- Copyright
- Contributors
- Preface
- Chapter One: Growth differentiation factor 15 (GDF-15) in kidney diseases
- Abstract
- 1 Introduction
- 2 The expression of GDF-15 in the kidney
- 3 GDF-15: A biomarker for albuminuria, hospitalization and mortality in the general population
- 4 The relationship between GDF-15 and kidney diseases
- 5 Treatment
- 6 Conclusion
- References
- Chapter Two: Alkaptonuria – Past, present and future
- Abstract
- Abbreviations
- 1 Introduction
- 2 Genetics
- 3 The biochemical problem: a vicious cycle of disease
- 4 Clinical sequelae
- 5 Treatment of Alkaptonuria
- 6 Metabolomic and proteomic insights into Alkaptonuria and response to nitisinone treatment
- 7 Summary and future perspectives
- Acknowledgement
- References
- Chapter Three: Drinking and laboratory biomarkers, and nutritional status characterize the clinical presentation of early-stage alcohol-associated liver disease
- Highlights
- Abstract
- 1 Introduction
- 2 Biomarkers of liver injury
- 3 Biomarkers of heavy and chronic drinking in early-stage ALD
- 4 Nutrition
- 5 Gut barrier function
- 6 Conclusion/summary
- References
- Chapter Four: Advances in liquid biopsy–based markers in NSCLC
- Abstract
- 1 Introduction
- 2 cfDNA
- 3 CTCs
- 4 cfRNAs
- 5 Exosomes
- 6 Summary and future perspectives
- Acknowledgments
- References
- Chapter Five: D-dimer testing: A narrative review
- Abstract
- 1 D-dimer: a multifaceted laboratory parameter
- 2 Preanalytical considerations
- 3 Analytical considerations
- 4 Postanalytical considerations
- 5 Clinical applications
- 6 Conclusions
- References
- Chapter Six: Evolving markers in amyotrophic lateral sclerosis
- Abstract
- 1 Introduction
- 2 Epidemiology of ALS
- 3 Potential mechanisms of ALS
- 4 Markers-sources and technologies
- 5 Summary and future perspectives
- Acknowledgment
- References
- Index
- No. of pages: 270
- Language: English
- Edition: 1
- Volume: 114
- Published: June 1, 2023
- Imprint: Academic Press
- Hardback ISBN: 9780443192883
- eBook ISBN: 9780443192890
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USARead Advances in Clinical Chemistry on ScienceDirect