Books in Molecular biology cellular biology and genetics

Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part B

1st Edition
Volume 392
May 1, 2025
Carolina Reduzzi + 2 more
English
Hardback
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eBook
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Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part B, Volume 392 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Circulating Tumor Cells in Lung Cancer: integrating stemness and heterogeneity to improve clinical utility, Multi-omic Features and Clustering Phenotypes of Circulating Tumor Cells Associated with Metastasis and Clinical Outcomes, CTCs in CRC: updates, Proteomics and post-translational modification analysis in CTCs, Latest advances of CTC studies in prostate cancer, and Epigenetics and CTCs: new biomarkers and impact on tumor biology.

Techniques and Protocols in Molecular Biology

1st Edition
May 1, 2025
Buddhi Prakash Jain
English
Paperback
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eBook
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Techniques and Protocols in Molecular Biology delivers detailed practical guidance for a variety of molecular techniques and procedures. Each chapter focuses on a different technique, including isolation techniques for DNA and RNA, gene cloning, PCR, DNA sequencing, ELISA and cell culture. These protocols all includes a detailed description of the technique along with the main principles, required equipment, and comprehensive steps to assist researchers with replicating the protocol and performing the techniques themselves.This foundational reference is essential for students and researchers looking to enhance their understanding of key molecular techniques and reproduce them successfully in their own laboratory work.

Raising Genomics Literacy, Knowledge, and Awareness

1st Edition
May 1, 2025
Azhar T. Rahma + 1 more
English
Paperback
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eBook
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Raising Genomics Literacy, Knowledge, and Awareness is a unique resource which describes the importance of genomic literacy for the effective and streamlined implementation of genomic medicine and pharmacogenomics globally. It provides evidence and expert opinion to decipher the role of genomic and pharmacogenomic literacy to illustrate the evidence, value, and need of raising genomics awareness and education among healthcare professionals, students, and the general public. This text can be used by researchers and graduate students pursuing research in this area.

Handbook of Translational Transcriptomics

1st Edition
April 22, 2025
Anton Buzdin
English
Paperback
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eBook
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Handbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview on the field of transcriptomics. The book begins with an overview of the past, present, and potential approaches in the field of transcriptomics, with discussions on choosing the correct approach based on the research needed. The book also highlights the pros and cons of each approach and explores techniques and protocols for investigating specific avenues, focusing on RNA sequencing, expression arrays, and gene expression. Sections on data analysis offer recommendations, guidelines, and approaches related to data interpretation.The book also considers the translation of transcriptomics to clinical application and applications in molecular diagnostics, biomarkers in medicine, and personalized medicine specific to oncology, as well as biotechnology for pharmaceutical research.

Cholecystokinin

1st Edition
April 7, 2025
Christine Feinle-Bisset + 1 more
English
Paperback
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eBook
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Cholecystokinin: From Gallbladder to Cognition and Beyond covers the biology, physiology, and pathophysiological roles of cholecystokinin (CCK) peptides. The book begins with a historical overview before providing in-depth chapters on the biology of CCK, from biogenesis to cell expression, including intestinal and extraintestinal endocrine cells, the central and peripheral nervous system, and receptor function. CCK phylogenesis is explored across various species, including fish, birds, insects and amphibians. The physiology of CCK covers intestinal CCK secretion, the gallbladder and pancreas, and the role of CCK in the gut-brain axis, gastrointestinal motor function, appetite regulation, and cardiovascular function.Methods used for CCK research are also discussed. A number of chapters then covers the roles of CCK in various diseases, including metabolic diseases, tumors, psychiatric illness, the immune system and nociception, as well as potential therapeutic approaches targeting CCK receptors.

Nutritional Epigenomics

2nd Edition
Volume 14
April 1, 2025
Bradley S. Ferguson
English
Paperback
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eBook
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Nutritional Epigenomics, Second Edition, Volume Fourteen in the Translational Epigenetics series, offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health, and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes.Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. This new edition has been fully updated to reflect current research in the field.

The Immunological Synapse Part C

1st Edition
Volume 193
April 1, 2025
Clément Thomas + 1 more
English
Hardback
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eBook
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The Immunological Synapse - Part C, Volume 193 in the Methods in Cell Biology series provides state-of-the-art and detailed methods for the study of the T cell, natural killer (NK) cell and B cell immunological synapses. Topics covered in this third volume include tau-STED microscopy for 3D-quantitative colocalization of lytic granule markers, image processing approaches for 3D-analysis of markers and for microtubule remodeling quantification at the immunological synapse, flow cytometry to analyze NK cell-target cell conjugation, imaging flow cytometry to quantify a range of different subcellular processes at the immunological synapse, imaging techniques aimed at quantitatively analyzing B cell immunological synapse formation, quantification of force-mediated antigen extraction in the B cell immune synapse using DNA-based tension sensors, measuring interaction forces between T lymphocytes and their target cells using live microscopy and laminar shear flow chambers, measuring interaction kinetics between T cells and their target tumor cells with optical tweezers, and gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice. Additionally, this volume includes methods to isolate and characterize primary NK cells and enrich the KIR2DL1+ population, and to expand γδ T cells and evaluate their cytotoxicity.

Circulating biomarkers for diagnosis, prognosis and treatment response prediction in cancer - Part A

1st Edition
Volume 391
April 1, 2025
Lorenzo Galluzzi + 1 more
English
Hardback
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eBook
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Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer Patients, Part A, Volume 391 delves into the crucial role of circulating biomarkers in cancer diagnosis and treatment monitoring. Specific chapters in this new release include Circulating biomarkers for diagnosis and response to therapies in cancer patients, Identification of circulating tumor DNA as a biomarker for diagnosis and response to therapies in cancer patients, Identification of cell-free circulating epigenomic biomarkers for early diagnosis and response to therapies in breast cancer patients, Expanding frontiers in liquid biopsy-discovery and validation of circulating biomarkers in renal cell carcinoma and bladder cancer, and much more.This comprehensive work explores the various types of biomarkers, their significance in early cancer detection, prognostication, and evaluation of therapeutic responses. It covers cutting-edge research on circulating tumor cells, cell-free DNA, exosomes, and other biomarkers that can revolutionize cancer management. Additionally, it discusses the challenges, advancements, and future prospects of utilizing circulating biomarkers in personalized cancer care.

Computational Genomics and Structural Bioinformatics in Microbial Science

1st Edition
March 31, 2025
Javid Ahmad Parray + 2 more
English
Paperback
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eBook
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Computational Genomics and Structural Bioinformatics in Microbial Science: Microbial Genomics (Volume 2) covers different aspects of microbial genomics, metagenomics, and functional studies of microbes through informative illustrations of current trends in computational tools and bioinformatics approach in environmental microbiology and clinical diagnosis. This book aims to provide readers with an overview of the microbial genome, computational genomics, and structural bioinformatics in microbial science, as well as the most recent developments in these fields. This book covers a range of topics, including the challenges and opportunities of computational epigenomics, bioinformatics tools for assessing metagenomic data, as well as computed comparative genomics and computational phenotyping of microorganisms relevant to agriculture. Microbial Genomics: Host Adaptation, virulence, and Evolution is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, that are interested in microbial science specifically related to the microbial genome, computing genomics, and bioinformatics.

Host Adaptation, Virulence, and Evolution

1st Edition
March 31, 2025
Javid Ahmad Parray + 2 more
English
Paperback
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eBook
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Microbial Genomics: Host Adaptation, Virulence, and Evolution covers different aspects of microbial genomics, metagenomics, and functional studies of microbes that have provided a significant understanding of microbial-host interactions, virulence function, host adaptation mechanisms, including microbial evolution. Microbial Genomics: Host Adaptation, virulence, and Evolution is a comprehensive source on the latest updates and applications of microbial genomics information to understand the plant, microbe interaction, host adaptation, virulence nature of the infectious pathogen, microbial evolution, host-pathogen interactions contribute to shaping the genetic diversity of both organisms. Sections include an introduction to Microbial Genomics, followed by sections on Plant Microbiome, Genome Editing Prospecting and Approaches, Microbial virulanse and disease incidence. The final section of the book covers Microbial Genomics and evolutionary concepts. “Microbial Genomics: Host Adaptation, virulence, and Evolution” is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, industries, and government agencies that are interested in the microbial science specific to the microbial genome, virulence function of pathogenic microbes, host adaptation, evolution of microbes, and all other disciplines related to molecular microbiology.

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