Books in Molecular biology cellular biology and genetics

Computational Genomics and Structural Bioinformatics in Microbial Science

1st Edition
February 24, 2025
Javid Ahmad Parray + 2 more
English
eBook
9 7 8 0 4 4 3 3 1 5 5 1 0

Computational Genomics and Structural Bioinformatics in Microbial Science: Microbial Genomics (Volume 2) covers different aspects of microbial genomics, metagenomics, and functional studies of microbes through informative illustrations of current trends in computational tools and bioinformatics approach in environmental microbiology and clinical diagnosis. This book aims to provide readers with an overview of the microbial genome, computational genomics, and structural bioinformatics in microbial science, as well as the most recent developments in these fields. This book covers a range of topics, including the challenges and opportunities of computational epigenomics, bioinformatics tools for assessing metagenomic data, as well as computed comparative genomics and computational phenotyping of microorganisms relevant to agriculture. Microbial Genomics: Host Adaptation, virulence, and Evolution is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, that are interested in microbial science specifically related to the microbial genome, computing genomics, and bioinformatics.

Host Adaptation, Virulence, and Evolution

1st Edition
February 24, 2025
Javid Ahmad Parray + 2 more
English
Paperback
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eBook
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Microbial Genomics: Host Adaptation, Virulence, and Evolution covers different aspects of microbial genomics, metagenomics, and functional studies of microbes that have provided a significant understanding of microbial-host interactions, virulence function, host adaptation mechanisms, including microbial evolution. Microbial Genomics: Host Adaptation, virulence, and Evolution is a comprehensive source on the latest updates and applications of microbial genomics information to understand the plant, microbe interaction, host adaptation, virulence nature of the infectious pathogen, microbial evolution, host-pathogen interactions contribute to shaping the genetic diversity of both organisms. Sections include an introduction to Microbial Genomics, followed by sections on Plant Microbiome, Genome Editing Prospecting and Approaches, Microbial virulanse and disease incidence. The final section of the book covers Microbial Genomics and evolutionary concepts. “Microbial Genomics: Host Adaptation, virulence, and Evolution” is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, industries, and government agencies that are interested in the microbial science specific to the microbial genome, virulence function of pathogenic microbes, host adaptation, evolution of microbes, and all other disciplines related to molecular microbiology.

Genetic and Genome-Wide Microbial Insights: Bioenergy

1st Edition
February 24, 2025
Javid Ahmad Parray + 2 more
English
Paperback
9 7 8 0 4 4 3 3 1 5 5 6 5
eBook
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Genetic and Genome-Wide Microbial Insights: Bioenergy: Microbial Genomics (Volume 3) delves into the cutting-edge developments in the field of metagenomics, encompassing both metatranscriptomics and metaproteomics. This comprehensive resource highlights the significant potential of metagenomics in screening previously uncultivated microbial species. It underscores the pivotal role of these advanced genomic techniques in accessing elusive microorganisms, thereby revolutionizing the production of biofuels. This book emphasizes the practicality of these methods, aiming to make biofuel production more economically feasible and efficient. "Genetic and Genome-Wide Microbial Insights: Bioenergy" offers both a foundational overview and the most recent advancements in microbial genomics, computational genomics, and enzyme engineering. It details the process of upscaling and bio-prospecting microbial strains, specifically tailored for biofuel production, providing a comprehensive guide that bridges basic concepts with cutting-edge research. This book covers a range of topics, including advanced microbial fuel production techniques, Sustainable bioenergy (genomics and biofuel development) and microbial engineering. The comprehensive chapters in this book will appeal to readers from diverse backgrounds in biology, life sciences, agriculture, environmental engineering, genome engineering, and even medicine.

Circulating biomarkers for diagnosis, prognosis and treatment response prediction in cancer - Part A

1st Edition
Volume 391
February 21, 2025
Lorenzo Galluzzi + 1 more
English
Hardback
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eBook
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Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer Patients, Part A, Volume 391 delves into the crucial role of circulating biomarkers in cancer diagnosis and treatment monitoring. Specific chapters in this new release include Circulating biomarkers for diagnosis and response to therapies in cancer patients, Identification of circulating tumor DNA as a biomarker for diagnosis and response to therapies in cancer patients, Identification of cell-free circulating epigenomic biomarkers for early diagnosis and response to therapies in breast cancer patients, Expanding frontiers in liquid biopsy-discovery and validation of circulating biomarkers in renal cell carcinoma and bladder cancer, and much more.This comprehensive work explores the various types of biomarkers, their significance in early cancer detection, prognostication, and evaluation of therapeutic responses. It covers cutting-edge research on circulating tumor cells, cell-free DNA, exosomes, and other biomarkers that can revolutionize cancer management. Additionally, it discusses the challenges, advancements, and future prospects of utilizing circulating biomarkers in personalized cancer care.

The Immunological Synapse Part C

1st Edition
Volume 193
February 4, 2025
Clément Thomas + 1 more
English
Hardback
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eBook
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The Immunological Synapse - Part C, Volume 193 in the Methods in Cell Biology series provides state-of-the-art and detailed methods for the study of the T cell, natural killer (NK) cell and B cell immunological synapses. Topics covered in this third volume include tau-STED microscopy for 3D-quantitative colocalization of lytic granule markers, image processing approaches for 3D-analysis of markers and for microtubule remodeling quantification at the immunological synapse, flow cytometry to analyze NK cell-target cell conjugation, imaging flow cytometry to quantify a range of different subcellular processes at the immunological synapse, imaging techniques aimed at quantitatively analyzing B cell immunological synapse formation, quantification of force-mediated antigen extraction in the B cell immune synapse using DNA-based tension sensors, measuring interaction forces between T lymphocytes and their target cells using live microscopy and laminar shear flow chambers, measuring interaction kinetics between T cells and their target tumor cells with optical tweezers, and gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice. Additionally, this volume includes methods to isolate and characterize primary NK cells and enrich the KIR2DL1+ population, and to expand γδ T cells and evaluate their cytotoxicity.

Retinoids in Development and Disease

1st Edition
Volume 161
January 29, 2025
Norbert Ghyselinck + 1 more
English
Hardback
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eBook
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Retinoids in Development and Disease, Volume 161 in the Current Topics in Developmental Biology series focuses on the role of retinoids during development and disease. Topics covered include Retinoids, Retinol-Binding Protein 2 (RBP2), Retinol-Binding Protein 4 (RBP4): Obesity and Metabolic Disease, Early Retinoic Acid Signaling Organizes the Body Axis and Defines Domains for the Forelimb and Eye, Rethinking Retinoic Acid Self-Regulation: A Signaling Robustness Network Approach, Meiotic initiation in the fetal ovary without retinoic acid receptors: an unforeseen twist, Action of retinoic acid on progenitor cells in the testis, amongst many other topics.Additional sections cover Retinoic acid homeostasis and disease, Redefining the roles of endogenously produced retinoic acid in heart development and regeneration: lessons from genetic models, The Multifaceted Roles of Retinoids in Vision, Eye Development, and Retinal Degenerative Diseases, Essential roles for retinoid signaling in craniofacial development, and much more.

Epigenetic Regulation of Cancer - Part D

1st Edition
Volume 390
January 27, 2025
Lorenzo Galluzzi + 1 more
English
Hardback
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eBook
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Epigenetic Regulation of Cancer, Part D, Volume 390 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Revisiting Epigenetic Regulation in Cancer: Evolving Trends and Translational Implications, Epigenetic Alteration in Cervical Cancer Induced by Human Papillomavirus, Integrative analysis of transcriptome, chromatin accessibility, cell surface antigen in single cell level for AML, Role of miRNAs as epigenetic regulators of immune checkpoints in lung cancer immunity, and much more.Other chapters cover The translational potential of epigenetic modulatory bioactive phytochemicals as adjuvant therapy against cancer, Strategies for improving chemotherapeutic sensitivity and the epigenetic regulation of doxorubicin resistance, and more.

Animal Models of Disease Part C

1st Edition
Volume 192
January 24, 2025
Lorenzo Galluzzi + 3 more
English
Hardback
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eBook
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Animal Models of Disease, Part C, Volume 192 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors, The current models unravel the molecular mechanisms underlying the intricate pathophysiology of Alzheimer’s disease using Zebrafish, Colitis mouse model, Matching model with mechanism: appropriate animal models for studying various aspects of diabetes pathophysiology, Human cancer cells xenografts to assess the efficacy of granulysin-based therapeutics, and much more.Additional sections cover Antimicrobial regime for gut microbiota depletion in experimental mice models, Evaluating polyglutamine protein aggregation and toxicity in transgenic Caenorhabditis elegans models of Huntington's disease, A model of intraperitoneal ovarian cancer to study tumor responses to radioimmunotherapy, Metallic nanoparticles biodistribution for the study of lymphoma in animal models, Stereotactic injection of murine brain tumor cells for neuro-oncology studies, Evaluating amyloid-beta aggregation and toxicity in transgenic Caenorhabditis elegans models of Alzheimer's disease, and much more.

Artificial Intelligence in Microbiology: Scope and Challenges volume-II

1st Edition
Volume 56
January 24, 2025
Akanksha Srivastava + 1 more
English
Hardback
9 7 8 0 4 4 3 2 9 6 2 6 0
eBook
9 7 8 0 4 4 3 2 9 6 2 7 7

Artificial Intelligence in Microbiology: Scope and Challenges, Volume-II, Volume 56 covers changes due to the emergence of Artificial Intelligence (AI). AI is being used to analyze massive data in a predictable form, about the behavior of microorganisms, to solve microbial classification-relat... problems, and more. Chapters include Taking on the resistance: AI and battle against antimicrobial resistance, AI-powered insights into microbial communities for bioremediation strategies, Efficient and cost-effective production of viral vaccines via AI, Production and development of novel drug targets through AI, Use of AI in neuroscience, Role of Artificial Intelligence in studying metagenomics of Microbes: Decoding the microbial Sphere, and more.Other chapters explore Exploring the functional role of bacterial proteins via AI, Application of AI in Aquaculture/Fisherie... Disease identification, detection, diagnosis, drug development, Artificial Intelligence in drug discovery & development; scope and challenges, Production of bacteriocins by AI: as food preservative, Exploring the Role of Artificial Intelligence in the Microbial remediation of heavy metals, Uses of Artificial Intelligence in the Agricultural Pest Management, Microbial fermentation processes using Artificial Intelligence, and more.

Immuno-oncology and immunotherapy Part C

1st Edition
Volume 191
January 16, 2025
Lorenzo Galluzzi + 2 more
English
Hardback
9 7 8 0 4 4 3 2 9 6 2 0 8
eBook
9 7 8 0 4 4 3 2 9 6 2 1 5

Immuno-oncology and immunotherapy, Part C, Volume 191 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Extraction and quantification of histones from human cells, Expression and characterization of Phosphatidylserine-t... antibodies for biochemical and therapeutic applications, ILC differentiation from HSCs in vitro, Methods to expand human Treg cells and assay their function, Monitoring rapid activation of human gamma/delta T cells by multicolor flow cytometry, Methods to induce T cell exhaustion in vitro, Ex vivo assessment of human neutrophil motility and migration, and much more.Additional chapters focus on Flow cytometry-based monitoring of myeloid-derived suppressor cells in the peripheral blood of patients with solid tumors, Deciphering human blood and tumor neutrophil heterogeneity: Methods for isolation and assessing suppression of T-cell proliferation, Splenocyte anticancer citotoxicity assessment after prophylactic vaccination or drug treatment of tumor-bearing mice, Therapeutic treatment of tumor-bearing mice with drug-killed cancer cells: a method to confirm immunogenic cell death and assess its therapeutic effectiveness, and much more.

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