Molecular biology cellular biology and genetics print books and ebooks | Elsevier

Fundamentals of Molecular Structural Biology

2nd Edition
Subrata Pal
English

Fundamentals of Molecular Structural Biology, Second Edition reviews the mathematical and physical foundations of molecular structural biology, covering the latest advancements. The book begins with historical perspectives before exploring mathematical concepts, physical aspects of chemistry, the chemical basis of biology, structural analysis, visualization, protein folding, transcription, RNA processing, cell signaling, and computational molecular biology. Additionally, this new edition delves into AI fundamentals and applications, including AlphaFold and RoseTTAFold. This fully updated edition provides a detailed overview of the fundamental concepts across molecular structural biology and acts as an ideal guide for researchers and advanced students.Given the increasingly interdisciplinary nature of this subject, this book provides early career researchers and those shifting into an adjacent field a "fundamentals" resource to get them up-to-speed on the foundations of a particular field.

Immunomodulators

1st Edition
Volume 151
English

Immodulators, Volume 151 explores the pivotal role immodulators play in regulating immune responses for health and disease management. The book provides an in-depth overview of various classes of immunomodulatory agents, including biologics, small molecules, natural compounds, and synthetic drugs, examining their mechanisms of action and therapeutic applications. Chapters in this new release include Marine-Derived Polysaccharides and Peptides as Next-Generation Immunomodulators: Molecular Mechanisms, Therapeutic Potential, and Translational Challenges, Advances in Immunomodulation: From Dietary Influence to Computational Precision, iPSC-derived immunotherapy for Tau and Alzheimer's disease, and much more.Additional sections cover Antibodies targeting amyloid-β and Tau oligomers in Alzheimer's Disease, Biosimilars: Antibody and Nanobody Based Therapeutic Approaches Towards Protein Misfolding Diseases, Immunomodulator drugs: mechanisms of action and systemic effects, Microbiome and microbial products as immunomodulators: implication for gastrointestinal cancers, Integration of Network pharmacology, docking, and dynamics analysis to investigate the immunomodulatory activity of Pongamia pinnata, Transcriptomic Insights into Epigenetic and Immunomodulatory Roles of Nuclear Histone Genes in Bladder Cancer: A bioinformatics Approach, Utilizing DREIMT Database for Drug Prioritization in Immunomodulatory Therapy for Psoriasis and Psoriatic Arthritis, and many additional topics.

Cell Death Part B

1st Edition
Volume 206
English

Cell Death Part B continues the comprehensive exploration of cellular mechanisms governing the fate of cells in health and disease. This volume delves deeper into the molecular pathways, regulatory networks, and biological consequences of various cell death modalities, including apoptosis, necrosis, autophagy, ferroptosis, pyroptosis, and other emerging forms.

Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment

1st Edition
Volume 169
English

Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment, Volume 169 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include an Introduction to Nanotechnology in Dermatology, Basics of Skin Cancer: Types, Diagnosis, and Current Challenges, Current Challenges in Skin Cancer Diagnosis and Treatment, Nanocarriers for Drug Delivery in Skin Cancer, Nanotechnology in Skin Cancer Diagnosis, Therapeutic Nanoparticles and Targeted Therapy, and much more.Additional chapters cover Nanotechnology in Photodynamic and Photothermal Therapy for Skin Cancer, Challenges in Translating Nanotechnology from Research to Clinical Practice, Nanotechnology and Immunotherapy Synergies in Skin Cancer, Patient-Centric Approaches and Personalized Nanomedicine in Skin Cancer, The Role of Theranostics and Nanotheranostics in Skin Cancer Management, Preclinical and Clinical Trials in Nanotech Skin Cancer Treatment, Safety, Ethical, and Regulatory Considerations in Nanotechnology for Skin Cancer, and many more interesting chapters on topics of current interest.

Cell Death Part A

1st Edition
Volume 205
English

This comprehensive volume explores the diverse mechanisms and methodologies underlying cell death, providing an up-to-date resource for researchers and clinicians in the biomedical sciences. The book brings together leading experts to discuss both established and emerging approaches for studying cell death, with a strong emphasis on practical laboratory techniques and their applications in disease research and drug discovery.

Sustainable Microalgal Biorefinery

1st Edition
Naim Rashid + 1 more
English

Sustainable Microalgal Biorefinery, a new release in the Developments in Microbial Cell Factories: From Design to Commercial Production series, introduces readers to the cellular biology of microalgae and explores their transformative potential across multiple industries. The book begins with a comprehensive overview of microalgae biorefinery systems, highlighting the latest research and the current challenges in the field. It delves into the essential properties of microalgae and investigates their applications in biofuel production, water purification, bioplastics, carbon capture, aquaculture feed, and the creation of high-value bioproducts for food, biotechnology, and pharmaceuticals.With a focus on recent advances, the text examines innovative photobioreactor designs and the role of genetic engineering in optimizing microalgal outputs. Beyond technological advancements, the book evaluates the social, environmental, and economic sustainability of microalgae-based solutions, emphasizing their contribution to achieving United Nations Sustainable Development Goals. It is an indispensable reference for researchers and professionals in cell biology, renewable energy, biotechnology, biochemical engineering, pharmaceutical sciences, and environmental science.

Apolipoprotein E in Health and Disease

Unravelling its Intricate Roles

1st Edition
Dileep Kumar + 2 more
English

Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles offers a thorough investigation into Apolipoprotein E (ApoE), emphasizing its importance across a spectrum of health conditions. This book details ApoE’s structure, genetic diversity, and functional significance, exploring how this protein impacts cardiovascular health, Alzheimer’s disease, neurological disorders, metabolic syndrome, and more. Through well-researched chapters, it highlights ApoE’s influence on lipid metabolism, heart disease, and the genetic factors contributing to Alzheimer’s, establishing the foundation for precision medicine and targeted therapeutic interventions. Beyond its primary focus, the book also examines ApoE’s broader effects on cognitive decline, liver function, cancer susceptibility, and immune responses.It delves into the pharmacogenetics of ApoE, addressing how genetic variations shape medication effectiveness and treatment plans. Innovative topics such as infectious disease management, genetic engineering, and advanced drug delivery systems are discussed, making this resource valuable for researchers, clinicians, and students alike.

Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control

1st Edition
Ramesh Kumar Ahirwar + 4 more
English

Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control presents an in-depth overview of innovative approaches in plant metabolomics, focusing on their practical integration into industry. The book examines advanced techniques such as metabolic engineering, metabolite imaging, NMR analysis, microfluidics, and computational bioinformatics. These methods are crucial for identifying and optimizing bioactive compounds in plants, reflecting the growing demand for natural products and plant-derived therapeutics. Through detailed case studies, readers gain insight into real-world applications and scenarios, making this resource invaluable for professionals aiming to enhance accuracy and efficiency in metabolite profiling.In addition to pharmaceutical applications, the book explores the use of plant metabolomics in crop improvement, archaeological studies, cosmetic development, and food quality assurance. It offers a multidisciplinary perspective, highlighting the significant impact of plant metabolites across sectors such as molecular and cellular biology, biotechnology, and biochemistry. Specialists in pharmaceuticals, nutraceuticals, cosmetics, and agriculture will find this comprehensive guide essential for staying abreast of the latest advances and understanding the broad implications of plant metabolite research.

Unlocking the Secrets of Extracellular Vesicles and Exosomes

A Journey into the Cutting-Edge Frontier of Cellular Communication

1st Edition
Chandrashekhar Singh + 4 more
English

Unlocking the secrets of extracellular vesicles and exosomes: A journey into the cutting-edge frontier of cellular communication provides a comprehensive overview of the latest advances and research on extracellular vesicles (EVs) and exosomes. The book begins with a historical introduction to the field and how this has evolved since EVs were first observed, before exploring their cellular mechanisms and approaches to study their isolation, characterization, and function. It then delves into exosomes in health and disease, considering their role across cancer, regenerative medicine, neurological disorders, and metabolic disorders, highlighting their potential as biomarkers for disease diagnosis. The book moves on to discuss cutting-edge technology for the engineering of EVs and exosomes, considering how the integration of AI, machine learning, and nanotechnology can be utilized to expand the therapeutic capabilities of EV and exosome-based applications. It then closes with chapters covering novel applications in nutraceutical and cosmetic production, and a look towards the future potential of EVs and exosomes. Unlocking the secrets of extracellular vesicles and exosomes offer a thorough exploration of EV and exosome research, covering various dimensions from basic science to clinical applications and future perspectives. It is an ideal guide for researchers working across a diverse range of disciplines, including cell biology, molecular biology, biotechnology, therapeutics, and biomedicine.

2D and 3D Cellular Screening Models and AI Guided Analysis

1st Edition
Volume 204
English

2D and 3D Cellular Screening Models and AI Guided Analysis provides a comprehensive overview of the latest advancements in cellular screening models, with a particular focus on both 2D and 3D systems. It explores the development, application, and comparative benefits of 2D monolayer cultures and 3D organoids, spheroids, and tissue-engineered constructs for biomedical research and drug discovery.

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