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Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • Advances in Applied Mechanics: Letters

    • 1st Edition
    • Volume 63
    • English
    Advances in Applied Mechanics, Volume 63 highlights new advances, with this volume presenting interesting chapters written by an international board of authors. Chapters in this release cover higher order discontinuous Galerkin finite element methods for the contact problems, Anisotropic Recovery-Based Error Estimators and Mesh Adaptation Tailored for Real-Life Engineering Innovation, Adaptive mesh refinement on Cartesian meshes applied to the mixed finite element discretization of the multigroup neutron diffusion equations, and more. Other sections cover a posteriori error analysis for Finite Element approximation of some groundwater models Part I: Linear models, a posteriori error estimates for low frequency electromagnetic computations, and more.
  • Autophagy – Part C

    • 1st Edition
    • Volume 406
    • English
    Autophagy, Part C, Volume 406 dives cellular housekeeping, weaving together the mechanistic precision of modern biology with the larger questions of health, aging, and resilience. Building on the foundations laid in Parts A and B, this book takes the reader from the microscopic machinery inside a single cell to the sweeping implications for organisms, ecosystems, and medicine. Chapters cover Lysosomal Function and Homeostasis: From Cellular Adaptation to Disease Pathogenesis, Autophagy Meets Plant Virology: From Molecular Crosstalk to Outstanding Challenges, Impact of mitophagy on obesity-affected tissues, Autophagy in Endothelial Cells: a gatekeeper of immune cell trafficking and function, and much more.Additional sections cover Viral Trafficking: The Role of Autophagy in the Release of Virus-Loaded Extracellular Vesicles and Sex matters in macroautophagy: sex-driven differences in autophagic function in aging and aging related-diseases.
  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 89
    • English
    Advances in Microbial Physiology, Volume 89 explores the latest research and developments in microbial physiology, providing a comprehensive overview on how microorganisms function, adapt, and interact with their environments. This volume brings together leading experts to discuss fundamental processes such as metabolism, growth, gene regulation, signal transduction, stress responses, and cellular differentiation in bacteria, archaea, and fungi. Chapters cover Steroids as Antibacterials, From Feeding Cell to Fruiting Body: Multidrug Transport in the Life cycle of Dictyostelium discoideum, Evolution of xenobiotic catabolism, Glycyl-radical enzymes, How anaerobes cope with oxygen, and Extracellular Electron Transfer: From Early Life to Modern Biogeochemistry and Applications.
  • Microbial Biofilms and Cancer - Part B

    • 1st Edition
    • Volume 225
    • English
  • Lifestyle Epigenomics

    • 1st Edition
    • Ana B Crujeiras
    • English
    Lifestyle Epigenomics, a new volume in the Translational Epigenetics series, comprehensively details the interplay between lifestyle factors and epigenetic modifications associated with the onset of noncommunicable diseases and aging, shedding light on potential preventive and therapeutic strategies for disease from an epigenomics perspective. Here, more than 35 international experts in the field consider how lifestyle choices or habits can condition or prevent disease, along with tools for new research, from bioinformatics methodology to non-invasive sampling.Early, foundational chapters are followed by all-inclusive sections on epigenetic machinery in health and disease; dietary factors and epigenetics; adiposity and physical activity and epigenetics; psychological stress, social environment, toxins and contaminants exposure effects on epigenetics; and transgenerational and childhood epigenetics. To support understanding, each chapter includes a summary and key points lists, terms and definition, as well as research case studies outlining core components of recent studies, detailing their conditions, research techniques involved, and outcomes.
  • Radiation Biology

    Molecular Foundations and Clinical Applications
    • 1st Edition
    • Barry S. Rosenstein + 1 more
    • English
    Radiation Biology: Molecular Foundations and Clinical Applications is a comprehensive exploration of the effects of radiation on living organisms, delving into the molecular mechanisms underlying cellular responses. This book examines critical topics such as radiation-induced DNA damage, repair processes, and molecular signaling pathways. It provides a detailed look at how cells respond to radiation, addressing cell cycle control, apoptosis, and the effects of radiation on immune system functionality. As a resource for researchers, it bridges the gap between molecular biology and clinical oncology, offering insights into radiation's role in both therapeutic contexts and its broader impact on human biology.In addition to its focus on molecular responses, the book covers topics like tumor microenvironment and metabolism, the role of epigenetics in radiation biology, and the hallmarks of cancer relevant to radiation therapy. It also provides discussions on chemotherapeutic agents, radiation carcinogenesis, and the complex interplay between radiation and cancer biology. The later sections extend the scope to tissue, organ, and systemic effects of radiation, making it an invaluable reference for professionals in molecular biology, oncology, and related fields striving to push the boundaries of radiation research.
  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 134
    • English
    Advances in Applied Microbiology, Volume 134 presents a comprehensive exploration of the latest innovations in applied microbiology. The book delves into the diverse applications of microbiology across various industries, including agriculture, food production, biotechnology, environmental science, and healthcare. Through a collection of insightful chapters authored by experts in the field, readers are offered in-depth analyses of cutting-edge research, emerging trends, and practical applications of microbiological principles. From novel microbial technologies to the impact of microbiomes on human health and beyond, this book serves as a valuable resource for researchers, professionals, and students seeking to stay informed and inspired by the exciting advancements.
  • Fundamentals of Absorption Spectroscopy

    • 1st Edition
    • Imtaiyaz Hassan
    • English
    Fundamentals of Absorption Spectroscopy offers a clear and comprehensive introduction to the principles, instrumentation, and applications of absorption spectroscopy across UV-Visible, IR, and other spectral regions. Designed for students, researchers, and industry professionals, this book bridges theory and practice with practical illustrations and real-world case studies, providing a solid foundation in both fundamental concepts and contemporary applications in chemistry, biology, medicine, environmental monitoring, and materials science. It fills the gap between overly advanced and overly simplified texts by combining fundamental theory with practical insights, particularly from biological perspectives. This book addresses the need for an updated, student-friendly, and application-oriented resource in absorption spectroscopy. Readers will benefit from structured guidance that connects theoretical principles with experimental data, explains instrumentation and its limitations, and demonstrates applications across diverse fields such as pharmaceuticals, environmental analysis, and biomolecular sciences. The inclusion of case studies and recent advances in spectroscopic technology ensures relevance for both academic study and professional practice.
  • Microbial Tryptamine as a Causative Cofactor of Incurable Cell Death Diseases of Unknown Etiology

    The Cost of Related Healthcare in the US and Worldwide
    • 1st Edition
    • Elena L. Paley
    • English
    Microbial Tryptamine as a Causative Cofactor of Incurable Cell Death Diseases of Unknown Etiology: The Cost of Related Healthcare in the US and Worldwide investigates microbial tryptamine and its role in a range of diseases, such as Alzheimer’s disease and Parkinson’s disease, while also examining the economic burden of these conditions on global healthcare systems. The book begins with an examination of microbial tryptamine’s significance across neurodegenerative diseases, cancers, and gastrointestinal conditions. It covers the implications of tryptamine in cell and organ transplantation, as well as the roles of diet and environment in tryptamine-induced disease progression. Additionally, the latest advances in treatment and prevention are considered. It then provides a critical analysis of expenditure on diseases related to tryptamine-induced cell toxicity and neurodegeneration, alongside an evaluation of current funding and market analysis. Following this, the author delves into research-related issues that may hinder biomedical progress, such as competition, plagiarism, and retractions of funded peer-reviewed articles. Collaboration between researchers and medical doctors is also examined. The book concludes with the author’s own personal narrative and recommendations, emphasizing the need for open discussions to drive urgent changes in biomedical research funding and review processes.
  • RNases in Health and Diseases

    From Housekeeping Enzymes to Moonlight Proteins
    • 1st Edition
    • Ester Boix
    • English
    RNases in Health and Diseases: From Housekeeping Enzymes to Moonlight Proteins provides coverage of the structural and functional properties of RNases, introducing new concepts such as their recently discovered multifaceted properties, their involvement in the generation of non-coding signaling RNAs, and their proposed uses as diagnostic and therapeutic tools. This book's sections cover the structure of RNases, present research methods and tools to study RNases, and delve into RNases and diseases. Users will find a wider perspective on the topics discussed that will serve researchers and students engaged in the study of RNases who are interested in acquiring a better understanding.
  • Gene Therapy in Neurodegenerative Disorders

    From Bench to Bedside
    • 1st Edition
    • Vahid Mansouri + 1 more
    • English
    Gene Therapy in Neurodegenerative Disorders: From Bench to Bedside offers a comprehensive review of gene therapy modalities and their applications in treating neurodegenerative disorders. Initial chapters focus on the fundamentals of gene therapy strategies, including gene delivery methods and CNS-targeted gene delivery. Subsequent chapters delve into specific neurodegenerative disorders such as Spinal Muscular Atrophy (SMA), Amyotrophic Lateral Sclerosis (ALS), Duchenne Muscular Dystrophy (DMD), and Alzheimer's Disease (AD), highlighting the latest gene therapy approaches for each condition. Each chapter provides a detailed introduction to the relevant field before exploring specific tools and applications.With contributions from leading experts, the book addresses current and ongoing clinical trials, potential challenges, and promising advances in gene therapy for neurodegenerative disorders. It also discusses regulatory and ethical considerations in translating research from bench to bedside. This book is an essential resource for basic science researchers in gene therapy, geneticists, biotechnologists, and clinical researchers seeking new and effective treatments for neurodegenerative diseases. It equips readers with the knowledge and tools needed to advance their work and drive innovation in gene therapy.
  • Advances in Genomics and Neurosciences for Neurologic and Behavioral Disorders

    • 1st Edition
    • Moyra Smith
    • English
    Advances in Genomics and Neurosciences for Neurologic and Behavioral Disorders explores the latest breakthroughs in genomics and neurosciences, providing essential insights for understanding, diagnosing, and managing neurodevelopmental, psychiatric, and neurodegenerative disorders. The book highlights the intersection of genetic and genomic diagnostic techniques with brain function and structure analysis to enhance therapeutic strategies. Sections cover a wide range of topics, including the analysis of brain circuits, synapses, and neural activity, as well as the role of ion channels and neurotrophins in brain function. It examines advanced genetic and genomic diagnostic methods such as chromosome studies, gene sequencing, RNA analysis, and metabolite profiling.The book also addresses neurodevelopmental disorders like cerebral palsy, epilepsy, and autism, psychiatric disorders such as schizophrenia and thought disorders, and the molecular biology of memory and age-related cognitive decline. Organized into five sections, the book includes chapters on the latest techniques for brain analysis, genetic diagnostics, neurodevelopmental and psychiatric disorders, aging-related impairments, and new therapeutic approaches. Key topics include brain regions and circuits, new methods for studying these areas, and the relevance of this information for accurate diagnosis and patient care.
  • Advances in Marine Biology

    • 1st Edition
    • Volume 104
    • English
    Advances in Marine Biology, Volume 104, the latest release in this serial that highlights new advances in the field, includes comprehensive chapters written by an international board of authors. Chapters in this new release explore Integrative Fish Biomechanics and Advancing marine invertebrate biodiversity in South Africa: Addressing gaps in taxonomy and genetic knowledge.
  • miRNA in Human Disease

    From Biomarkers to Therapeutics
    • 1st Edition
    • Parul Gupta + 6 more
    • English
    miRNA in Human Disease: From Biomarkers to Therapeutics explores the critical role of microRNAs (miRNAs) in the development and progression of various diseases, emphasizing their significance as biomarkers and therapeutic targets. Sections provide a comprehensive overview of the biogenesis, function, and regulation of miRNAs, offering insights into how these small noncoding RNA molecules influence gene expression and contribute to disease development and progression. The book covers traditional and advanced methods for miRNA extraction, the role of miRNAs in infectious diseases, cancer, neurological disorders, cardiovascular disease, hemoglobinopathies, pregnancy complications, and metabolic disorders.Sections also discuss the latest research on miRNA-based therapies, including the design and delivery of miRNA mimics and inhibitors and their potential applications in personalized medicine. With a strong focus on practical implementation, the book includes detailed case studies and real-world examples that demonstrate the clinical relevance of miRNA research. It addresses the challenges and future directions in the field, providing a roadmap for researchers, clinicians, and industry professionals to harness the potential of miRNAs for disease diagnosis, treatment, and prevention.
  • Cryo-EM Methods and Management

    • 1st Edition
    • Edward T. Eng + 2 more
    • English
    Cryo-EM Methods and Management provides a detailed introduction to the latest advances of cryo-EM, from technical innovations to the logistical challenges of maintaining a modern cryo-EM facility. The book consists of four parts, beginning with an overview of cryo-EM. It then moves on to discuss Cryo-EM workflows, with chapters focusing on sample handling and preparation, data collection and hardware, and data procession and visualization. The third part centers on aspects of cryo-EM infrastructure and community building, considering facility set-up and management, monitoring facility performance, instrumentation monitoring , data sharing and standards, and training and development standards. The book then closes with a section looking towards future prospects for cryo-EM. This is an ideal reference for cryo-EM facility and lab managers, providing guidance to the often-overlooked aspect of facility building and management. Additionally researchers working with cryo-EM across molecular biology, structural biology, cell biology and biochemistry will benefit from this book.
  • Advanced Technologies for Disease Intervention

    Innovations Across Precision Medicine, Nutrition and Holistic Therapies
    • 1st Edition
    • Ranbir Chander Sobti + 3 more
    • English
    Advanced Technologies for Disease Intervention: Innovations Across Precision Medicine, Nutrition and Holistic Therapies, Two Volume Set investigates current and emerging advances in disease detection, diagnosis, treatment and prevention, and how molecular medicine and biotechnology have contributed to this changing landscape. Volume One focuses on sustainable health practices through biotechnology, exploring traditional health systems, diagnostic innovations, and integrative therapies. Key topics include: the role of traditional medicine and practices in sustainable health; contemporary and emerging technologies such as aptamer diagnostics, telemedicine, nanomaterials and AI in healthcare, and much more.Volume Two then delves deeper into emerging technologies for disease intervention, focusing on drug development, delivery systems, nutrition, and natural products for health. Themes explored here include: developments and trends in drug discovery; drug repurposing; contemporary drug delivery systems; phototherapeutics; personalized drug delivery; innovations in vaccine development; the role of nutraceuticals in disease prevention; and the use of natural products and herbal interventions for sustainable health.
  • Molecular Insights into Proteinopathies

    Increased Scope from Neurodegeneration to other Pathologies of the Brain
    • 1st Edition
    • Eva Žerovnik + 1 more
    • English
    Molecular Insights into Proteinopathies: Increased Scope from Neurodegeneration to other Pathologies of the Brain investigates the molecular events that lead to various diseases. The book is divided into four parts, the first of which delves into protein aggregation across a range of diseases, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, and neuropsychiatric diseases. It then moves on to discuss signaling pathways and biomarkers of disease, including oxidative stress, mitochondrial decline, and dysregulated molecular pathways. The third part explores small molecules as modulators of key processes in the pathogenesis of proteinopathies, including antioxidants, polyphenol compounds, metal chelators, and repurposed drugs that modulate proteinopathies.The final section considers biophysical methods, molecular dynamics, and machine learning approaches in the study of these aspects. The book provides a detailed overview of protein dysfunction and its implications for health and disease, aiding understanding of protein condensates and aggregates, protein misfolding, co-chaperoning and toxicity of pre-amyloid aggregates. By understanding the fundamental properties underlying these, the book paves the way for investigating how proteinopathies could be treated.
  • Thiamine and Thiamine-Pyrophosphate (TPP) Riboswitches

    • 1st Edition
    • Volume 735
    • English
    This volume of "Methods in Enzymology" series is devoted to the cofactor thiamine, also known as vitamin B1, and its phosphorylated derivatives. The biosynthesis of thiamine is discussed in terms of key enzymes and their regulation, the evolution of metabolic pathways, and its importance in plant and yeast metabolism. The importance of quantifying and distinguishing between phosphorylated and unphosphorylated thiamine in animal and human tissues using chromatographic, enzymatic, and nanopore methods is also discussed. In addition to these methods, thiamine riboswitches are a major focus of this book, covering everything from their identification in plants and the elucidation of their structure to their application in detection.This book presents state-of-the-art methods and detailed protocols intended for all researchers interested in thiamine metabolism or its detection.
  • Cell Death Part E

    • 1st Edition
    • Volume 210
    • English
    Cell Death: Part E, Volume 210 presents the latest advances and comprehensive reviews in the rapidly evolving field of cell death. This volume explores the molecular mechanisms, regulatory pathways, and biological consequences of various forms of cell death—including apoptosis, necrosis, autophagy, and other non-canonical processes. Chapters in this new release include Flow cytometry analysis of mitochondrial apoptotic priming with BH3 profiling on senescent cells, Methods to study PIDDOsome and caspase 2 signaling, Isolation, characterization, and experimental applications of apoptotic bodies in vitro, Lipid ROS Measurement by Spectral Flow Cytometry based on the ratiometric dye BODIPYTM C11 581/591, and much more.Additional chapters cover CRISPR-Cas9 Screen to Identify Genes Regulating Cell Death, Flow cytometry-assisted discrimination of early apoptotic, late apoptotic and primary necrotic morphological markers in Saccharomyces cerevisiae, Cytofluorometric analysis of cell death in primary human neutrophils, Real-time tracking of cell death in human intestinal organoids: a quantitative imaging approach, and more.
  • Alternative Proteins

    • 1st Edition
    • Volume 154
    • English
    Alternative Proteins, Volume 154 provides a comprehensive overview of alternative proteins, exploring their sources, production technologies, nutritional profiles, and potential to transform the global food system. Covering plant-based, microbial, insect, and cultured (cell-based) proteins, the book examines the scientific advances, market trends, regulatory challenges, and sustainability implications of these innovative protein sources. Chapters in this new release include Introduction to Alternative Proteins, Molecular Properties of Plant-Based Proteins for Alternative Proteins, The Science of Alternative Proteins: Comparing Animal and Plant-Based Sources, Blue Proteins: Marine-Derived Alternatives for Sustainable Nutrition and Climate-Resilient Food Systems, and much more. Additional sections cover Insect Proteins for Alternative Proteins: Sustainable Solutions with Molecular Efficiency, Plant-Based Proteins: Key Sources and Production Methods, Fungal proteins as Eco-friendly Alternate Proteins, Algae and Microbial Proteins for Alternative Proteins: Untapped Molecular Resources, Integrating Siddha Dietary Principles with Alternative Protein Systems: A Pathway Toward Sustainable and Functional Nutrition, Alternative Proteins: Structure and Functional Properties, and a variety of extensive and timely topics.
  • Advances in Cancer Research

    • 1st Edition
    • Volume 172
    • English
    Advances in Cancer Research, Volume 172 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Memantine and its Analogs: Potential Applications in Cancer Therapy, The role of epigenetic modifications in mediating cancer health disparities, Tumor Associated Macrophages: Ontogeny, Plasticity, Spatial Ecosystems, and Therapeutic Targeting, Recognizing the significance of cancer-nerve crosstalk in advanced prostate cancer, and much more.
  • Microbial Biofilms and Cancer - Part A

    • 1st Edition
    • Volume 224
    • English
    Microbial Biofilms and Cancer series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Histone Deacetylases in Neurodegenerative Disease Part B

    • 1st Edition
    • Volume 734
    • English
    Histone Deacetylases in Neurodegenerative Disease, Part B, Volume 734 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics surrounding the Interaction of HDAC6 ZnF UBP with Tau affects its stability by NMR and Simulation studies, Protocols for In Vitro Analysis of Liquid-Liquid Phase Separation of Proteins, Histone deacetylases in NS, Histone Deacetylase 6 ZnF UBP domain enhances podosome formation in neuronal cells studied by high-resolution confocal microscopy, Methodological approach to Investigate Peroxiredoxin 1 Deacetylation by Histone Deacetylase 6, Critical structural features of HDAC11 inhibitors, and much more.Additional chapters in this release include Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration, Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin, Protein acetylation dynamics (histone and non-histone) and role protein deacetylases in disease, Epigenetic Clues: Predicting Maternal Depression Through DNA Methylation, A short guide on in vivo transfection of flag-HDAC4 in dentate gyrus for study of adult neurogenesis in brain trauma, Decoding the Acetylation Journey from Neural Crest to Melanocyte, and more.
  • Microbial Technologies for Sustainable Waste Management

    • 1st Edition
    • Rajneesh Kumar + 2 more
    • English
    Microbial Technologies for Sustainable Waste Management explores advanced waste management through microbial processes. The book investigates the current limitations of traditional waste treatment and the potential for microbial cell factories in bringing innovative solutions to this field. Beginning with an introduction to the role of microbes in waste management, it examines global case studies demonstrating success stories in microbial waste treatment and microbial innovations for biotechnological applications in waste conversion. Concluding chapters focus on microbial pathways for anaerobic digestion, hydrolysis, and fermentation, and microbial technologies for industrial applications such as wastewater treatment and the biofuel industry.Additionall... the book considers microbial remediation of hazardous and toxic waste, microbial fuel cells, and strategies for plastic waste degradation. Emerging technologies, such as AI integration, microbial nanotechnology, and engineered microbes are discussed, along with their environmental impacts and potential for scaling up to commercial applications.
  • Genome Damage

    Repair and Adaptation Across Life
    • 1st Edition
    • Vinod K. Kannaujiya + 2 more
    • English
    Genome Damage: Repair and Adaptation Across Life explores the significance of nucleic acid damage from environmental pollutants, UV radiation, and other stressors that can lead to mutations, genetic instability, and various diseases, including cancer. This book delves into the mechanisms of DNA and RNA repair, which are crucial for maintaining cellular health and enabling evolutionary adaptations. It examines these intricate processes across microbes, plants, and animals, providing a comprehensive understanding of how genetic materials are regulated and repaired under diverse environmental conditions.Other sections cover a wide range of topics, including advanced molecular mechanisms of nucleotide repair, UV-induced damage, apoptosis cell death and autophagy, genetic instability in crops, and the role of post-translational modifications in DNA repair, the detection and quantification of DNA damage, the impact of synthetic chemicals and climate change on nucleic acids, and the therapeutic significance of DNA repair mechanisms. The book closes with a look towards future perspectives.
  • Mitochondrial Intoxication

    • 2nd Edition
    • Marcos Roberto de Oliveira
    • English
    Mitochondrial Intoxication, Second Edition, offers a comprehensive and fully updated exploration of the impact of toxic molecules on mitochondrial physiology and the diseases that result from their dysfunction. Divided into three sections, the book opens with a detailed overview of mitochondrial physiology, molecular markers of mitochondrial intoxication, and challenges of mitochondrial profiling during pre-clinical studies. The book then focuses on endogenous toxicants and their impact on mitochondria, including new chapters on lipids, glucose and microbiota-derived toxicants. Amyloid-β peptide and its impact on mitochondrial dysfunction is also a new addition to this book, as well as inflammation-induced mitochondrial intoxication.The final section explores exogenous toxicants, such as pollutants, food additives, illicit and pharmaceutical drugs, pesticides, and heavy metals. The effects of micro- and nanoplastics on mitochondrial function are newly covered. Furthermore, the latest computational tools in mitochondrial toxicity research are investigated. Incorporating the latest advances in the field, this new release offers cutting-edge insights on mitochondrial toxicity, serving as an invaluable resource for researchers and advanced students in cell biology, molecular biology, toxicology, biochemistry, pharmacology, and related fields.
  • Advances in Structural Biology

    Applications in Protein Structure, Function, and Disease
    • 1st Edition
    • Anas Shamsi + 3 more
    • English
    Advances in Structural Biology: From Protein Structures to Function and Disease offers a comprehensive, practical resource that bridges the latest experimental and computational approaches in structural biology. Backed by real-world case studies, the book demonstrates how these technologies can be utilized to serve a range of biological needs. The content spans foundational principles of protein structure and bioinformatics tools, cutting-edge methodologies such as MicroED and Cryo-EM, and the transformative role of artificial intelligence and big data analytics in structural biology. It also considers applications including drug discovery, vaccine development, antiviral therapy, personalized medicine, and the structural basis of aging and neurodegenerative diseases.Readers will find detailed investigation into the latest developments in structural and computational biology, including insights into integrative methodologies that combine both traditional and emerging technologies. This resource is invaluable for advanced students, researchers, and professionals aiming to harness structural biology for innovative solutions in precision medicine and translational research.
  • Clinical Genomics

    A Guide to Clinical Next Generation Sequencing
    • 2nd Edition
    • Shashikant Kulkarni + 1 more
    • English
    Clinical Genomics, Second Edition is a comprehensive, practical reference [AN1] designed specifically for laboratory directors, clinical medical directors, and genomic medicine professionals. Edited by renowned genomic pathology leaders Kulkarni and Roy, this updated edition offers clear guidance on the current technical, bioinformatic, clinical, regulatory, and reimbursement considerations involved in implementing next-generation sequencing technologies within clinical molecular diagnostic laboratories.Structu... for ease of reference, this book covers targeted gene sequencing methods, whole exome/genome approaches, emerging technologies such as long-read sequencing, and critical considerations for assay validation. Detailed sections address bioinformatics workflows, variant detection and interpretation methodologies, integration with clinical informatics systems, and essential IT infrastructure, including cloud-based solutions.This book also thoroughly addresses practical topics essential to laboratory management, such as regulatory compliance, ethical frameworks, billing strategies, and reimbursement paradigms, helping directors navigate the evolving landscape of genomic diagnostics.
  • Histone Deacetylases in Neurodegenerative Disease Part A

    • 1st Edition
    • Volume 733
    • English
    Histone Deacetylases in Neurodegenerative Disease, Part A, Volume 733 in the Methods in Enzymology series, highlights new advances, with this volume presenting chapters on topics such as HDAC Inhibitor-Induced Endoplasmic Reticulum (ER) Stress, Specific activation of p300/CBP Lysine acetyltransferases induces adult neurogenesis and synaptic plasticity, Chromatin immunoprecipitation assay for analyzing histone H3-mediated regulation of copper homeostasis, Histone Deacetylase 6 modulates Tau structure and function, Histone Acetylation in Parkinson Disease, DNA methylation and histone modification in hypoxic conditions, The extracellular Histone Deacetylase 6 modulates the actin networks in neuronal cells, Epigenetic modulators as therapeutics for neurodegenerative disorder/Alzheimer's disease, and much more.Additional chapters explore Sirtunins in mitochondrial physiology and energy homeostasis, Sirtunins in metabolic homeostasis, Conformational flexibility of histone variant CENP-ACse4 is regulated by histone H4: A mechanism to stabilize soluble Cse4, Analysis of copper toxicity by western blotting of secretory proteins translocated via Sec61 channel, Histone deacetylase as a potential therapeutic target for memory disorders, Histone deacetylases in Neurodegeneration, Role of Deubiquitinases in Regulating Tau Acetylation and Autophagic Clearance in Alzheimer’s Disease, Histone deacetylases in Neurodegeneration and neuronal plasticity, and more.
  • Non-Invasive Prenatal Screening of Rare Fetal Genetic Diseases

    • 1st Edition
    • Riyaz Ahmad Rather
    • English
    Non-Invasive Prenatal Screening of Rare Fetal Genetic Diseases offers a comprehensive exploration of the latest advancements in non-invasive prenatal screening (NIPS) technologies and their application in detecting rare fetal genetic disorders. It provides a detailed overview of current methods in NIPS technology, the application of NIPS in detecting rare genetic disorders, and ethical considerations. Sections cover advanced genomic methods such as Next-Generation Sequencing, Single-Nucleotide Polymorphism analysis, and Comparative Genomic Hybridization, highlighting their impact on the accuracy and scope of NIPS, while also exploring specific genetic disorders, including Trisomy 18, Trisomy 13, Duchenne Muscular Dystrophy, Angelman Syndrome, Turner Syndrome, and Cri du Chat Syndrome.Researchers will find this to be a valuable resource for understanding and applying NIPS protocols in their work, while clinicians will benefit from practical insights on appropriate screening methods, interpreting NIPS results, and counseling expectant parents. This book is an essential resource for researchers in obstetrics and gynecology, genetic counselors, and professionals in the biotechnology and pharmaceutical industries. It equips readers with the knowledge and tools needed to advance their work and improve prenatal care practices.
  • Advances in Biosystems

    • 1st Edition
    • Xiaoli Li + 2 more
    • English
    Advances in Biosystems investigates the latest techniques for evaluating, detecting, measuring, and enhancing the functional bioactivities, chemical composition, and physicochemical characteristics of animal, plant, and environmental biosystems. This comprehensive, interdisciplinary handbook provides detailed explanations for tracking functional molecules during various biological processes, along with practical methodologies for both laboratory and industrial applications. Sections cover cellular biosystems advances, including single-cell microsystems and tissue system biology of plants and animals, alongside biomass microsystems and agricultural biosystems advances, exploring innovations in animal, plant, and crop biosystems, as well as food hydrocolloids and biotechnological advancements.Additio... content addresses environmental biosystems, discussing colloidal biosystems, nano and micro-biosystems, chemical toxicology, eco-friendly biosystems, and green chemistry, pharmaceutical biosystems, highlighting medical biosystems, human cellular metabolomics, nutrigenomics, and precision medicine applications. A final section presents in-depth analytical methods for tracking these various biosystems, including high-throughput technologies, deep learning, machine learning, bioinformatics models, and spectroscopic and sensor-based techniques.
  • Mpox

    • 1st Edition
    • Volume 59
    • English
    Monkeypox, Volume 59 covers the diagnosis of Mpox from clinical specimens and wastewater, while also discussing the neurological, dermatological, reproductive, and structural biology of Mpox. Specific chapters cover Tracking Mpox through Wastewater: Advances in Environmental Surveillance and Analytical Methodologies, Community-Based Monitoring of Mpox and Co-occurring Sexually Transmitted Infections (STIs), Clade-Level Differentiation of Mpox Virus: Molecular Diagnostic Strategies for Routine Testing in Low-Resource Settings, Comparative Analysis of Mathematical and Stochastic Modelling of MPOX in Human and Rodent Populations, Genomic Sequencing Methods for mpox Detection and Genotyping, and The gastrointestinal manifestations of mpox.Additional sections explore the Neurological complications of Mpox, Dermatological complications of Mpox infections, Reproductive complications of Mpox, and the Structural Biology of Mpox: Advanced Imaging Illuminate Viral Mechanisms.
  • Current Approaches to Cryo-electron Microscopy

    • 1st Edition
    • Volume 223
    • English
    Current Approaches to Cryo-electron Microscopy, Volume 223 provides a comprehensive overview of the field, tracing its evolution from early structural studies to modern pipelines powered by deep-learning algorithms for helical reconstruction. The book addresses the persistent bottleneck of sample preparation, detailing the physical challenges of fibril clumping and interfacial adsorption, alongside emerging solutions to these problems. Chapters in this new release include Advancing biological understanding of the poxvirus scaffold through breakthroughs in cryo-electron microscopy, Pursuing the physics of cryoEM image formation, AI Tools for Cryo-EM: Protein Particle Picking, Density Map Enhancement, and Atomic Model Building, and much more.Additional chapters cover Cryo-EM of Amyloid Fibrils: Advances, Challenges, and Translational Applications, Computational Approaches for Protein Complex Modeling for Intermediate Resolution Cryo-EM Maps, Calcium-sensing receptor, involved in the oral perception of the kokumi substances, Insights into the Structure and Diversity of the Bacterial Flagellum from cryo-EM studies, Overview and future potential in structural studies of bacteriophages by cryo-electron microscopy, and more.
  • Statistical Bioinformatics with R

    • 2nd Edition
    • Sunil K. Mathur
    • English
    Statistical Bioinformatics with R, Second Edition offers a balanced treatment of statistical theory within the context of bioinformatics applications. The book goes beyond gene expression and sequence analysis to include a careful integration of statistical theory in bioinformatics. The inclusion of R codes, along with the development of advanced methodologies such as Bayesian and Markov models, equips students with a solid foundation for conducting bioinformatics research. Sections incorporate the latest advancements in bioinformatics and statistical methodologies, including new chapters on cutting-edge topics such as high-throughput sequencing data analysis, AI/machine learning applications in bioinformatics, and advanced statistical methods.From new and updated practical examples and case studies that illustrate real-world applications of statistical techniques to bioinformatic problems to enhanced end-of-chapter exercises, detailed code annotations, and an improved companion website with supplementary materials, including datasets and R scripts, this book is a valuable resource for both self-study and formal coursework, fostering a deeper understanding of statistical bioinformatics and equipping readers with the skills needed to tackle complex biological data analysis challenges.
  • Molecular Targets and Therapeutic Design

    • 1st Edition
    • Volume 153
    • English
    Molecular Targets and Therapeutic Design, Volume 152 provides a comprehensive overview of the current landscape and future directions in the identification and exploitation of molecular targets for the development of new therapeutics. This volume brings together leading experts to discuss the fundamental principles of target discovery, validation, and the strategies used to design molecules that modulate biological pathways in disease. Topics covered in this new release include Recent Strategies and Approaches for the Development of Molecularly Targeted Nanomedicine, Transcriptomic Profiling for Therapeutic Target Discovery in Neuropsychiatric Conditions, Transcriptomic Insights into Hormone-Driven Malignancies: Toward Targeted Therapeutic Strategies, and much more.Additional chapters cover Targeting Kinases in Neurodegenerative Diseases and Cancer: Structural Insights and Therapeutic Strategies, Small molecular therapeutic targets for neurodegenerative diseases, Signaling cascades of Tau protein, Understanding molecular role of lipids for Alzheimer's disease, Clinical Challenges and Therapeutic Strategies in Chordoma, Molecular Characterization and Experimental Models of Chordoma, Disordered Proteins as Fuzzy Viral Drug Targets, amongst other timely topics.
  • Cell Death Part D

    • 1st Edition
    • Volume 209
    • English
    Cell Death, Part D, Volume 209 explores the latest advances in the mechanisms, regulation, and significance of cell death in health and disease. Covering diverse topics such as apoptosis, necrosis, autophagy, and emerging pathways, this volume presents chapters on Utilizing FLAMBE to study the structure-function relationship and regulation of monomeric BAX activation in solution, Sensitive detection of Lysosomal Membrane Permeabilization using the Galectin Puncta Assay, Assessing the activity of caspase-activated pannexin-1 channels by flow cytometry, In vitro culture of intestinal organoids for cell death assessments, Optimized Strategies for Necroptosis Induction and Evaluation, and more.Additional sections cover Ferroptosis induction via genetic approaches - CRISPR/Cas9-based disruption on key anti-ferroptotic genes, Reprogramming T cell fate through antibody-mediated galectin-1 blockade, 3D bioluminescence imaging assays for measuring in vitro CAR T cell cytotoxicity, The heat-ramp method to study regulated cell death in the pathogenic yeast Cryptococcus neoformans, High throughput assessment of cellular viability, and High-Throughput Screening for Cell Death Inducers and Inhibitors. This book will serve as a valuable resource for researchers, clinicians, and students interested in understanding cellular processes and their implications for therapy and diagnostics.
  • Ion Channels in Cellular Pathophysiology Part B

    • 1st Edition
    • Volume 98
    • English
    Ion Channels in Cellular Pathophysiology Part B, Volume 98 covers a variety of timely topics, including Nerve electrophysiological alterations in experimental diabetic neuropathy, Possible therapeutic effects of essential oils on Na channels in experimental diabetic neuropathy, Breast cancer and voltage gated ion channels, Cardioprotective effect of natural products on doxorubicin-induced acute cardiotoxicity and cardiac ischemia-reperfusion injury,and Modulation of ion channels by Group I metabotropic glutamate receptors.
  • Mucins

    • 1st Edition
    • Volume 732
    • English
    Mucins, Volume 732 serves as a valuable resource for researchers aiming to investigate mucin biology in greater depth, offering a wide range of experimental approaches and analytical strategies. Topics in this new release cover Enrichment/isolation... glycoproteomics, Mucinase cleavage characterization and usage in glycoproteomics, Fluorescent protein-based FRET substrates for activity screening of mucinases, Development of clinical lectin assays based on MS glycomic discovery, Enzymatic selective sulfation of synthetic mucins, cryoEM, Cell-based mucin arrays and glycoengineering, CRISPR screens to characterize and identify glycan-binding proteins, and much more.Additional sections cover MD Simulations, Interactions with pathogenic bacteria, Interactions with microbiota, Covalent crosslinking of mucins, Liquid Glycan and Liquid Lectin Array-based exploration of musin recognition, Quantification of mucins, Mucins in IBD, Investigations of mucins and innate immunity, Generating synthetic mucin glycopeptides, and Microscopy and imaging.
  • Protein Misfolding and Human Diseases

    Deciphering the Central Role of Pathological Aggregation
    • 1st Edition
    • Pranav Kumar Prabhakar + 2 more
    • English
    Protein Misfolding and Human Diseases: Deciphering the Central Role of Pathological Aggregation investigates the misfolding of proteins and implications for a variety of debilitating conditions. The book comprehensively overviews pathological protein aggregation, exploring its mechanisms in specific illnesses, including Alzheimer's disease, Parkinson’s disease, Huntington’s disease, prion diseases, ALS, and systemic amyloidosis. It addresses disrupted cellular pathways and failures in protein homeostasis during aging, delineating the unifying principles across protein conformational disorders. Sections feature structural insights into protein aggregates from amyloid fibrils to inclusion bodies and offer therapeutic strategies to disrupt aggregation pathways, enhance cellular protein quality control, and provide immunotherapy solutions.Finally, the book closes with a discussion of the latest advances in research and considerations for future directions to combat protein aggregation. It will serve as an invaluable reference on the intricacies of protein misfolding and its clinical implications. Researchers, academics and graduate students working across these fields will benefit from this comprehensive guide. Additionally, clinicians and healthcare professionals will find it invaluable for understanding the molecular basis of protein misfolding disorders.
  • Bioorthogonal Labeling

    • 1st Edition
    • Volume 731
    • English
    Biorthogonal Tagging, Volume 731 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters such as Staudinger Ligations and Related Reactions: Scope and Applications in Chemical Biology, Strain-Promoted Bioorthogonal Cycloadditions to Investigate Sialyltransferases Promiscuity Towards Unnatural Sialic Acids, Practical Guidelines for the Bioorthogonal AMI–Isonitrile Ligation, Nitrones and Other Dipoles in Bioorthogonal Chemistry Applications, 1,2-Aminothiol-Speci... Conjugation for Dual-Color Fluorescent Labeling via Ultrafast TAMMs, Genetic Incorporation of Bicyclononyne for Cell-Surface Protein Labeling via Tetrazine Ligation, and much more.Additional chapters cover Genetic Code Expansion for Single Noncanonical Amino Acid Incorporation into SARS-CoV-2 Omicron Spike on Amber-Free Lentiviral Particles, Bioorthogonal Click-Chemistry Labeling and Visualization of Dual Noncanonical Amino Acid–Incorporated HIV-1 Env on Intact Virions, Studying Bacterial Glycans with Azidosugars and Bioorthogonal Chemistry, Bioorthogonal Tagging of DNA and RNA, Efficient Labeling of Pathogenic Fungal Chitin with Bioorthogonal Probes, and many more timely topics.
  • Advances in Biomedical Engineering - Part B

    • 1st Edition
    • Volume 405
    • English
    Advances in Biomedical Engineering – Part B, Volume 405 presents the latest developments, research trends, and methodologies in the evolving field of biomedical engineering. This volume covers a range of topics, including advanced medical devices, biomaterials, biomedical imaging, tissue engineering, biomechanics, and computational modeling. Specific chapters in this new release include Advances in biomedical engineering, Recent advances in nanomedicine as drug delivery system, Advances in Nano biomaterials for Biomedical Engineering, Neurodiagnostic: Advances in diagnostic tools, Advances in Ferroptosis Research and Application, Bioink-based 3D Bioprinting: Paving the Path for Regenerative Medicine, MRI Acute/Sub-Acute Ischemic Stroke Segmentation with Deep Learning: A Comprehensive Review, and more.Contributions from leading experts highlight both theoretical advancements and practical applications designed to improve healthcare diagnostics, treatment, and patient outcomes. This comprehensive resource is ideal for researchers, practitioners, and students seeking to stay informed about cutting-edge technologies and future directions in biomedical engineering.
  • Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control

    • 1st Edition
    • Ramesh Kumar Ahirwar + 4 more
    • English
    Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control offers a comprehensive exploration of advanced methods in plant metabolomics, along with their integration in industrial applications across various sectors. The book delves into a range of methodologies, including metabolic engineering strategies, metabolite imaging techniques, nuclear magnetic resonance (NMR) for plant metabolite analysis, microfluidics for metabolite profiling, computational methods, and bioinformatics tools. It also explores plant metabolomics for crop improvement, pharmaceutical development, archaeological examinations, cosmetic formulations, and food quality, with case studies featured throughout the book to showcase real-world applications and scenarios. As the demand for natural products and plant-derived therapeutics continues to rise, there is a need for reliable and effective methods to identify, quantify, and optimize the bioactive compounds present in plants. This book provides a comprehensive guide to the latest advances in this field while also delivering a multidisciplinary overview of the wide-ranging impact plant metabolites have across a variety of applications. Researchers working with plant metabolites across molecular and cellular biology, pharmaceutical science, biotechnology, biochemistry and plant science will benefit from this book. Additionally, it will be of interest to specialists working across relevant industries, such as pharmaceuticals, nutraceuticals, cosmetics and agriculture.
  • Apolipoprotein E in Health and Disease

    Unravelling its Intricate Roles
    • 1st Edition
    • Dileep Kumar + 2 more
    • English
    Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease. In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.
  • Advances in Applied Mechanics

    • 1st Edition
    • Volume 62
    • English
    Advances in Applied Mechanics, Volume 62 highlights new advances, with this volume presenting interesting chapters written by an international board of authors. Chapters in this release cover higher order discontinuous Galerkin finite element methods for the contact problems, Anisotropic Recovery-Based Error Estimators and Mesh Adaptation Tailored for Real-Life Engineering Innovation, Adaptive mesh refinement on Cartesian meshes applied to the mixed finite element discretization of the multigroup neutron diffusion equations, and more.Other sections cover a posteriori error analysis for Finite Element approximation of some groundwater models Part I: Linear models, a posteriori error estimates for low frequency electromagnetic computations, and more.
  • Sustainable Microalgal Biorefinery

    • 1st Edition
    • Naim Rashid + 1 more
    • English
    Sustainable Microalgal Biorefinery, the latest release in Elsevier's Developments in Microbial Cell Factories: From Design to Commercial Production series, provides an overview of microalgae at the cellular level, along with their potential uses across a range of industries. Beginning with an introduction to microalgae biorefinery systems and the latest research and limitations, the book delves into the fundamental aspects of microalgae and their potential applications, such as biofuel production, water treatment, bioplastics production, carbon capture, aquaculture feed, and high-value bioproducts, including food, biotechnology, and pharmaceuticals. Photobioreactors design for microalgae are also covered, as well as genetic modifications to achieve desired bio-products. The book also focuses on assessing the social, environmental, and economic sustainability of microalgae technologies and how microalgae contributes to achieving UN SDG goals. This latest volume provides researchers with valuable insights into the transformation of traditional algal research and the recent trends of resource recovery and integrated technology that can be utilized to enhance sustainability and commercialization potential of microalgae.
  • Proteostasis and Cancer

    • 1st Edition
    • Buddhi Prakash Jain
    • English
    Proteostasis and Cancer explores the intricate mechanisms of protein homeostasis and their critical roles in cancer progression and therapeutics. The book delves into the mechanisms that control proteins inside the cell to preserve the health of the cellular proteome and the organism itself. It covers key topics such as post-translational modifications, protein folding, proteolysis, and the unfolded protein response (UPR), with a specific focus on their roles in cancer. Detailed discussions on molecular chaperones, the ubiquitin-proteasome system, and autophagy pathways offer valuable insights into how these processes contribute to cancer progression and how they can be targeted for therapeutic interventions.With clear explanations and well-labeled diagrams, the book makes complex concepts accessible to students and researchers alike. It also addresses the clinical implications of proteostasis in cancer, providing a foundation for developing innovative, therapeutic strategies. The book's multidisciplinary approach, combining insights from biochemistry, cancer biology, and medical sciences make it an essential resource for anyone seeking to understand the role of proteostasis in cancer.
  • Autophagy – Part B

    • 1st Edition
    • Volume 404
    • English
    Autophagy, Part B, Volume 404 provides an in-depth exploration of advanced mechanisms, functions, and roles of autophagy in health and disease. This volume features contributions from leading experts, covering recent developments in autophagy research, its implications in cellular homeostasis, neurodegeneration, cancer, immunity, and therapeutic strategies. Chapters in this new release include From autophagy to mitophagy: Quality control mechanisms in skeletal muscle, Impact of Different Exercise Modalities on Mitophagy in Human Skeletal Muscle, Eat, Heal, Repeat: How Zebrafish Master Regeneration, Pathophysiology, biological models and new therapeutic approaches in β-Propeller Associated Neurodegeneration, and more.Additional sections discuss Autophagy in adipose tissue thermogenic function and Non-selective and selective autophagy as mediators of mechanical forcest. Designed for researchers, clinicians, and students, the book offers valuable insights into the complexities and applications of autophagy in modern biomedical science.
  • Unlocking Sirtuins

    Cellular Biology to Translational Research
    • 1st Edition
    • Pranav Kumar Prabhakar + 1 more
    • English
    Unlocking Sirtuins: Cellular Biology to Translational Research explores the intricate roles of sirtuins, from basic principles to clinical significance. The book is organized into six parts, covering foundational concepts, roles in aging and metabolism, disease pathology, therapeutic strategies, future research directions, and potential challenges. Topics include the structure and evolution of sirtuins, their mechanisms of action, and their impact on neurodegenerative diseases, cardiovascular health, and cancer. The book also features detailed chapters on sirtuin modulators, drug discovery, the latest technologies and tools in the field, emerging trends, and the challenges, ethical considerations and future directions of sirtuin-targeted therapies.The book's content is complemented by case studies, clinical insights, and step-by-step procedures, offering a comprehensive and practical exploration of the subject. Users will find an in-depth overview of sirtuin biology, bridging fundamental science with clinical applications. This comprehensive resource will serve as an essential resource for researchers, clinicians, and advanced students working across cellular and molecular biology, biochemistry, pharmacology, aging, metabolic disorders, translational medicine, and related fields.
  • Cell Death Part C

    • 1st Edition
    • Volume 208
    • English
    Cell Death: Part C, Volume 208 continues the comprehensive exploration of cellular mechanisms governing the fate of cells in health and disease. This volume delves deep into the molecular pathways, regulatory networks, and biological consequences of various cell death modalities, including apoptosis, necrosis, autophagy, ferroptosis, pyroptosis, and other emerging forms.
  • Autophagy – Part A

    • 1st Edition
    • Volume 403
    • English
    Autophagy – Part A, Volume 403 explores the fundamental biological process of autophagy. Beginning with the historical discovery and molecular mechanisms of autophagy, the book delves into its regulation, physiological roles, and significance in maintaining cellular homeostasis. Chapters in this new release include Ciliophagy: Maintaining Primary Cilium Homeostasis to Prevent Cilium-Related Diseases, Unraveling the interplay of glycolysis, lactylation, and autophagy, Autophagy and Type 2 Diabetes: Bridging the Gap in Metabolic Health, Autophagy in Cancer Cachexia: From Mechanisms to Therapeutic Opportunities, Glycophagy: A Selective Autophagy Pathway for Glycogen Degradation, Role of Autophagy in Adipose Tissue: Implications for Metabolic Health, and more.