Books in Biochemistry biophysics

Advances in Clinical Chemistry

1st Edition
Volume 130
January 1, 2026
Gregory S. Makowski
English
eBook
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Transketolases

1st Edition
Volume 725
December 5, 2025
Franck Charmantray
English
Hardback
9 7 8 0 4 4 3 4 3 0 5 1 0
eBook
9 7 8 0 4 4 3 4 3 0 5 2 7

Transketolase is an ubiquitous enzyme which has not yet finished revealing all its secrets. This Methods in Enzymology: Transketolases volume is devoted to the description of cutting-edge methods to its study in biochemistry. Several topics are addressed by world experts in their field.The first part of this volume deals with transketolase at the cellular level. The latest scientific progress on human transketolase TKL1 in relation to certain diseases and to its inhibition are discussed including the involvement of this enzyme in new metabolic pathways or as a diagnostic biomarker.The second part focuses on transketolase at the molecular level. The structural and mechanistic aspects linked to this enzyme are addressed using several approaches including molecular modelling and crystallography, for example. Finally, the experimental methodological approaches relating to the use of transketolase as a tool of choice in biocatalysis is presented.

Fundamentals of Redox Biology

1st Edition
December 1, 2025
Shyamal K Goswami
English
Paperback
9 7 8 0 4 4 3 2 2 3 3 5 8
eBook
9 7 8 0 4 4 3 2 2 3 3 4 1

Fundamentals of Redox Biology is a comprehensive guide to understanding the complex roles of cellular redox systems in biological processes and human health. Exploring the regulation, physiological functions, and pathological implications of reactive oxygen species (ROS) and free radicals, this book serves as an essential resource for students and professionals in biochemistry and related fields. It delves into the fundamentals of redox signaling, the impact of antioxidants on homeostasis, and the intricate balance between oxidative stress and disease development, including conditions like cancer and neurological disorders. This foundational text is invaluable for advancing knowledge in redox biology.In addition to providing a historical perspective on redox biology, the book examines how ROS influence epigenetic regulation and mitochondrial function, particularly in immune responses to infections. It also integrates discussions on the role of redox systems across multiple disciplines, making it relevant to cell biology, molecular biology, immunology, and beyond. With its detailed exploration of both theoretical and applied aspects, the book positions itself as a pivotal resource for understanding the mechanisms underlying redox balance and its broad applications in life sciences.

Protein Misfolding Diseases

1st Edition
Volume 148
December 1, 2025
Ajaz A. Bhat + 1 more
English
Hardback
9 7 8 0 4 4 3 2 9 4 1 4 3
eBook
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Protein Misfolding Diseases, delves into the intricate molecular mechanisms behind a class of devastating disorders caused by abnormal protein folding. This comprehensive book explores interesting and updated topics, including Protein misfolding in hemophilia, Characterizing Protein Misfolding: Inside and Out, Heat Shock proteins (HSPs) as chaperones for Oncogenesis, Protein Misfolding and Cancer: Molecular Insights and Future Perspectives, Proteostasis and Pathogenesis: Unraveling the Complexity of Protein Misfolding Disorders, Small molecule inhibitors targeting α-synuclein aggregation: Progress and future outlook, and much more.Additional sections cover Chaperone Machinery in Neurodegeneration: A Spotlight on Protein Misfolding Diseases and Calpain- mediated proteolytic cleavage.

Antimicrobial Peptides and Proteins

1st Edition
Volume 149
December 1, 2025
Rossen Donev
English
Hardback
9 7 8 0 4 4 3 3 4 5 1 9 7
eBook
9 7 8 0 4 4 3 3 4 5 2 0 3

Antimicrobial Peptides and Proteins, Volume 148 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Nature and mechanistic action of Antimicrobial Peptides, Advances in elucidation molecular targets and mechanisms of action of AMPs: beyond membrane disruption, Discovery, Design, and Applications of Antimicrobial Peptides, Designing Potent Antimicrobial Peptides Against Acinetobacter baumannii: A Combined Approach Using Genetic Algorithms and Machine Learning Strategies, Protection of Diabetic Wound Patients from Invasive Bacterial Infections by Innate Antimicrobial Peptides, and more.Additional chapters explore Bacteriophage Lysins as a potential therapeutic strategy for Methicillin Resistant Staphylococcus aureus infections, Structural insights and therapeutic potential of host defense peptides in combatting antimicrobial resistance, Antimicrobial protein as a cargo for antimicrobial nanomaterials to combat Gram-negative bacteria, Unravelling the Role of Antimicrobial Proteins in Leptospirosis: A Comprehensive Transcriptomic Analysis, and Deciphering Antimicrobial Peptide (AMP) Resistance Mechanisms in Enterococcus faecalis Through Integrated RNA-Seq and Hub Genes Identification.

Microbial Enzymes

1st Edition
December 1, 2025
Abdel Moneim Elhadi Sulieman
English

Microbial Enzymes: Classification, Biochemistry, Production and Applications explores the multifaceted roles of microbial enzymes, emphasizing their stability, ease of handling, and manipulation, which make them invaluable in various industrial processes. This book serves as a comprehensive guide for understanding the classification, biochemical properties, production methods, and diverse applications of microbial enzymes. With 25 in-depth chapters, the book delves into the biochemistry of enzymes, their various sources, and their importance in biotechnology. It covers modern techniques for microbial enzyme detection and determination, methods of enzyme immobilization, and the application of microbial enzymes in industries such as food, medicine, pharmaceuticals, and textiles. Special sections discuss the biosynthesis of metal nanoparticles by microbial enzymes and the role of microbial toxins in different sectors. The chapters are organized to provide detailed insights into the classification of enzymes, the mechanisms of microbial enzymes, and their industrial importance. Topics include bacterial, fungal, and algal enzymes, their applications, and the latest advancements in enzyme technology. The book also addresses the challenge of antibiotic resistance and explores innovative methods for enzyme production and molecular engineering. This book is an essential resource for students, researchers, and professionals in the fields of food, pharmaceuticals, and textiles, offering them the latest knowledge and practical guidance to advance their work and innovate in their respective industries. It is designed to equip readers with a thorough understanding of microbial enzymes and their potential to revolutionize industrial processes.

Artificial Metalloproteins

1st Edition
Volume 724
December 1, 2025
Lisa Olshansky
English
Hardback
9 7 8 0 4 4 3 4 1 5 7 3 9
eBook
9 7 8 0 4 4 3 4 1 5 7 4 6

Artificial Metalloproteins covers artificial metalloproteins (ArMs) and how they have emerged as powerful vehicles with which to control, implement, and leverage the unique reactivity and spectroscopic properties of their bound metal ions. Chapters in this release include Incorporating Non-Native Cofactors into Heme Proteins, Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-... Cofactors, Cobalt-Substituted Hemoprotein Expression, Rationally designed directed evolution of cytochrome P450 enzymes, De novo design of a switchable a-helical hemoprotein, Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme, and more.Other sections cover Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes, Development of a PQQ-Dependent Artificial Metalloprotein, Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme, Design and Application of Nonheme Iron Enzymes, Part C: Secondary Sphere Modulation for Metallocofactor Activation, Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds, and much more.

Advances in Biomembranes and Lipid Self-Assembly

1st Edition
Volume 42
December 1, 2025
Aleš Iglič︎ + 2 more
English
Hardback
9 7 8 0 4 4 3 4 2 8 2 3 4
eBook
9 7 8 0 4 4 3 4 2 8 2 4 1

Advances in Biomembranes and Lipid Self-Assembly, Volume 42 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Bacterial Efflux Systems

1st Edition
Volume 723
November 15, 2025
Ben Luisi
English
Hardback
9 7 8 0 4 4 3 4 2 9 5 9 0
eBook
9 7 8 0 4 4 3 4 2 9 6 0 6

Bacterial Efflux Systems, Volume 722 covers experimental and computational approaches to study the function, structure, and mechanism of bacterial efflux pump systems. The methods covered include preparation of samples for structural and functional analyses and in vivo activity analysis. Specific chapters in this release cover Efflux pump functional assays, NMR and functional analysis efflux pumps, Methods for saturation mutagenesis and functional characterization, Cooperation and functional interplay between pumps, Mapping interactions, HDX-MS, and much more.Other sections cover Recombinant Expression and purification, Reconstitution of a RND efflux pump in different artificial membranes for a structural biology approach, Reconstitution of rnd and mfs efflux pumps for structural biology, CusCBA system, Expression and purification of efflux pumps of Gram positives, Expression and purification of efflux pumps of archaea, ABC transporters: BmrA preparation for NMR and PatA/PatB in peptidisc, In situ structural analysis of efflux assemblies by cryoET, Molecular dynamics simulations, and so much more.

Lipid Analysis in Biology, Health, and Disease

1st Edition
November 1, 2025
Sanjoy K. Bhattacharya
English
Paperback
9 7 8 0 4 4 3 1 9 1 1 6 9
eBook
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Lipid Analysis in Biology, Health, and Disease bridges the gap between discovery science and clinical lipidology, empowering both scientific and medical communities to apply lipid analysis and understanding in new research, as well as diagnosis and management of diseases. Here, international experts in the field begin with the basic biology of the lipids, followed by methods and technology for study, and lipids in lab medicine and epidemiology. This book uniquely combines biology and analysis to drive healthcare advances, with a diverse range of technologies and analytic methods considered.Basic lipid biology chapters discuss membrane expansion, lysosomal positioning, mitochondrial biogenesis, lipid-protein interactions, molecular dynamics, cholesterol transport, immune activation and inflammation, lipid droplets, and gender differences in lipid metabolism. Each disease chapter incorporates basic lipid epidemiology, risk factors, and genetic associations.

Related subjects

Bioenergetics

Biological transport

Biomembranes

Carbohydrate biochemistry

Clinical biochemistry

Comparative biochemistry

Enzymology

Free radicals

Lipids and lipid metabolism

Methodology techniques and instruments in biochemistry

Nucleic acids

Peptides amino acids amines amides

Physical biochemistry

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health