Lipid Analysis in Biology, Health, and Disease
- 1st Edition - September 26, 2025
- Editor: Sanjoy K. Bhattacharya
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 9 1 1 6 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 1 2 2 - 7
Lipid Analysis in Biology, Health, and Disease bridges the gap between discovery science and clinical lipidology, empowering both scientific and medical communities to apply lip… Read more
Lipid Analysis in Biology, Health, and Disease bridges the gap between discovery science and clinical lipidology, empowering both scientific and medical communities to apply lipid analysis and understanding in new research, as well as diagnosis and management of diseases. Here, international experts in the field begin with the basic biology of the lipids, followed by methods and technology for study, and lipids in lab medicine and epidemiology. This book uniquely combines biology and analysis to drive healthcare advances, with a diverse range of technologies and analytic methods considered.
Basic lipid biology chapters discuss membrane expansion, lysosomal positioning, mitochondrial biogenesis, lipid-protein interactions, molecular dynamics, cholesterol transport, immune activation and inflammation, lipid droplets, and gender differences in lipid metabolism. Each disease chapter incorporates basic lipid epidemiology, risk factors, and genetic associations.
- Covers diverse technologies for lipid research and analysis, as well as clinical applications from membrane simulation to drug delivery systems
- Includes applied, translational case studies, and research examples throughout
- Features chapter contributions from international experts in the field
Researchers in Biochemistry, Pharmacology, Physiology, Pathology, Bioinformatics, and Translational Medicine, Students and Clinicians
Section 1: Lipids in Different Aspects of Biology:
1. Membrane Expansion
2. Contribution of lipids towards membrane curvature
3. Lipid-Protein Interactions and Molecular Dynamics Simulation
4. Lipid Droplets in Biology
5. Lysosome and lipid metabolism
6. Mitochondrial and Cardiolipin Biology
7. Cholesterol transport by various lipoproteins
8. Lipids mediators in viral infection and immunity
9. Gender Differences in Lipid Metabolism
Section 2: Analytical Technologies
10. Analyses of different aspects of lipids: General methods
11. Current LC-MS/MS methods in lipidomics
12. Gas chromatography-mass spectrometry (GC-MS) analyses of lipids
13. Rapid and unbiased screening of serum lipid ratios using AP MALDI-HRMS
14. Nuclear magnetic resonance (NMR) methods for Lipid analysis
15. The statistical analysis of ‘Omics datasets: challenges, pitfalls, and tips
16. Differences in lipidomic analysis using different bioinformatics software
17. Metabolomics Tools for the Analysis of Phospholipids as Potential Markers to Decipher the Molecular Mechanisms Behind Diseases
18. Lipid Imaging: Microscopy-Based Techniques for Lipid Membrane Characterization
Section 3: Lipids in Lab and Investigational Medicine
19. Multi-omics biomarkers of health and disease
20. The Multifactorial Pathobiology of Lipidic Quorum Signaling Molecules of Pseudomonas aeruginosa
21. Targeting Fatty Acid Transport in Dietary Lipid Absorption: A Therapeutic Approach for Metabolic Disorders.
22. Lipoprotein metabolism and female fertility
23. The Role of Maternal Omega-3 Supplementation in Shaping Offspring Skeletal Health
24. Oxidized lipids and age-related macular degeneration
25. Lipidomics of Human Aqueous Humor
26. Drug Delivery Systems Involving Lipids
Section 4: Lipids in Clinical Medicine
27. Cardiovascular diseases and cholesterol
28. Cholesterol and Spingolipids in Alzheimer's disease
29. Cardiac lipotoxicity in diabetes and obesity
30. Lipid metabolism in type 1 diabetes initiation and progression to vascular disease
31. Role of the Gut Microbiome in Lipid Metabolism and type 1 diabetes
32. Elevated LDL levels and lung cancer
33. Pathophysiology and Clinical Medicine of Dyslipidemia after Spinal Cord Injury
34. Targeting transcription control of lipid biogenesis to tune intraocular pressure
35. Inflammatory Bowel Disease
36. Atherosclerosis and Inflammation
37. Lipidomics in Skeletal Muscle: Unveiling the Roles of Lipid Mediators in Muscle Biology
38. Lipidomics in Skeletal Muscle: Unveiling the Roles of Lipid Mediators in Muscle Pathophysiology
39. Lipidomics in Bone: Unveiling the Roles of Lipid Mediators in Bone Biology and Pathophysiology
40. Associations of Lipids With Diseases in Large Cohort Studies and Randomized Trials
1. Membrane Expansion
2. Contribution of lipids towards membrane curvature
3. Lipid-Protein Interactions and Molecular Dynamics Simulation
4. Lipid Droplets in Biology
5. Lysosome and lipid metabolism
6. Mitochondrial and Cardiolipin Biology
7. Cholesterol transport by various lipoproteins
8. Lipids mediators in viral infection and immunity
9. Gender Differences in Lipid Metabolism
Section 2: Analytical Technologies
10. Analyses of different aspects of lipids: General methods
11. Current LC-MS/MS methods in lipidomics
12. Gas chromatography-mass spectrometry (GC-MS) analyses of lipids
13. Rapid and unbiased screening of serum lipid ratios using AP MALDI-HRMS
14. Nuclear magnetic resonance (NMR) methods for Lipid analysis
15. The statistical analysis of ‘Omics datasets: challenges, pitfalls, and tips
16. Differences in lipidomic analysis using different bioinformatics software
17. Metabolomics Tools for the Analysis of Phospholipids as Potential Markers to Decipher the Molecular Mechanisms Behind Diseases
18. Lipid Imaging: Microscopy-Based Techniques for Lipid Membrane Characterization
Section 3: Lipids in Lab and Investigational Medicine
19. Multi-omics biomarkers of health and disease
20. The Multifactorial Pathobiology of Lipidic Quorum Signaling Molecules of Pseudomonas aeruginosa
21. Targeting Fatty Acid Transport in Dietary Lipid Absorption: A Therapeutic Approach for Metabolic Disorders.
22. Lipoprotein metabolism and female fertility
23. The Role of Maternal Omega-3 Supplementation in Shaping Offspring Skeletal Health
24. Oxidized lipids and age-related macular degeneration
25. Lipidomics of Human Aqueous Humor
26. Drug Delivery Systems Involving Lipids
Section 4: Lipids in Clinical Medicine
27. Cardiovascular diseases and cholesterol
28. Cholesterol and Spingolipids in Alzheimer's disease
29. Cardiac lipotoxicity in diabetes and obesity
30. Lipid metabolism in type 1 diabetes initiation and progression to vascular disease
31. Role of the Gut Microbiome in Lipid Metabolism and type 1 diabetes
32. Elevated LDL levels and lung cancer
33. Pathophysiology and Clinical Medicine of Dyslipidemia after Spinal Cord Injury
34. Targeting transcription control of lipid biogenesis to tune intraocular pressure
35. Inflammatory Bowel Disease
36. Atherosclerosis and Inflammation
37. Lipidomics in Skeletal Muscle: Unveiling the Roles of Lipid Mediators in Muscle Biology
38. Lipidomics in Skeletal Muscle: Unveiling the Roles of Lipid Mediators in Muscle Pathophysiology
39. Lipidomics in Bone: Unveiling the Roles of Lipid Mediators in Bone Biology and Pathophysiology
40. Associations of Lipids With Diseases in Large Cohort Studies and Randomized Trials
- Edition: 1
- Published: September 26, 2025
- Language: English
SB
Sanjoy K. Bhattacharya
Sanjoy Bhattacharya is a tenured full Professor at the Department of Ophthalmology, University of Miami, with secondary appointments in biochemistry, molecular biology, neuroscience, cellular and molecular pharmacology programs. He earned his doctorate in Biochemical Engineering and Biotechnology. Dr. Bhattacharya’s laboratory, with its diverse expertise in engineering, computer programming, biology, and mass spectrometry, is dedicated to studying the complete set of molecules and biological systems involved in axon regeneration. He serves on the editorial board of several peer-reviewed journals including PLoS One as an academic editor, Experimental Eye Research as Special issues and Review editor, and Translational Metabolomics as the Editor in Chief. Professor Bhattacharya has held several leadership positions including Chair of the scientific advisory board of Malignancy Research Foundation and Chair of Miller School of Medicine Faculty Council. He is also the founding director of Miami Integrative Metabolomics Research Center.
Affiliations and expertise
Professor of Ophthalmology, Graduate Program Director (MVSIO and Translational Focus of Medical School PhD Programs), Founding Director, Miami Integrative Metabolomics Research Center, Speaker, Medical School Faculty Council, University of Miami, Miami, FL, USA