Books in Free radicals

Reactive Species Detection in Biology

1st Edition
October 23, 2016
Frederick A. Villamena
English
Hardback
9 7 8 0 1 2 4 2 0 0 1 7 3
eBook
9 7 8 0 1 2 4 2 0 0 8 0 7

Reactive Species Detection in Biology: From Fluorescence to Electron Paramagnetic Resonance Spectroscopy discusses the reactive oxygen species that have been implicated in the pathogenesis of various diseases, presenting theories, chemistries, methodologies, and various applications for the detection of reactive species in biological systems, both in-vitro and in-vivo. Techniques covered include fluorescence, high performance chromatography, mass spectrometry, immunochemistry, and electron paramagnetic resonance spectroscopy. Probe design and development are also reviewed in order to advance new approaches in radical detection through synthesis, computations, or experimental applications.

Nitric Oxide

1st Edition
Volume 96
August 12, 2014
Gerald Litwack
English
Hardback
9 7 8 0 1 2 8 0 0 2 5 4 4
eBook
9 7 8 0 1 2 8 0 0 4 3 9 5

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on nitric oxide.

Nitric Oxide

2nd Edition
November 5, 2009
Louis J. Ignarro
English
eBook
9 7 8 0 0 8 0 9 2 0 4 4 3

Nitric oxide (NO) is a gas naturally found in the body that conveys information between cells. In the last decade researchers have found that NO is a signaling molecule of key importance for the cardiovascular system, regulating blood pressure and blood flow to different organs. In addition, discoveries surrounding nitric oxide’s role as a principal neurotransmitter moderating erectile function, a pathophysiological negotiator and messenger in inflammation, and a weapon against infections have increased research attention across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology.

Nitric Oxide, Part F

1st Edition
Volume 440
April 25, 2008
Enrique Cadenas + 1 more
English
Hardback
9 7 8 0 1 2 3 7 3 9 6 7 4
eBook
9 7 8 0 0 8 0 8 7 7 6 1 7

The discovery that nitrogen monoxide or nitric oxide (NO)is a biologically produced free radical has revolutionized our thinking about physiological and pathological processes. This discovery has ignited enormous interest in the scientific community. When generated at low levels, NO is a signaling molecule, but at high concentration, NO is a cytotoxic molecule. The physiological and pathological processes of NO production and metabolism and its targets, currently areas of intensive research, have important pharmacologic implications for health and disease.

Oxidative Stress and Neurodegenerative Disorders

1st Edition
March 22, 2007
G. Ali Qureshi + 1 more
English
Hardback
9 7 8 0 4 4 4 5 2 8 0 9 4
eBook
9 7 8 0 0 8 0 4 8 9 4 9 0

Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders.

Energy Metabolism and Lifespan Determination

1st Edition
Volume 14
December 1, 2003
M.P. Mattson
English
Hardback
9 7 8 0 4 4 4 5 1 4 9 2 9
eBook
9 7 8 0 0 8 0 4 9 4 7 6 0

Experts in the fields of energy metabolism, aging and oxidative stress provide an integrated view of how mechanisms involved in regulating energy metabolism are linked to fundamental processes of aging including cellular stress resistance and free radical production. During evolution signal transduction pathways and organ systems have been optimised for the efficient seeking, ingestion, storing and using of energy. These signalling pathways play prominent roles in lifespan determination with insulin and related signalling pathways being prime examples. The authors consider how lifespan and healthspan can be extended through knowledge of energy metabolism with the experimental model of dietary restriction being one example. The information in this volume of ACAG will foster novel approaches and experiments for further understanding the roles of energy metabolism in aging and disease.

Bio-Assays for Oxidative Stress Status

1st Edition
November 9, 2001
W.A. Pryor
English
Hardback
9 7 8 0 4 4 4 5 0 9 5 7 4
eBook
9 7 8 0 0 8 0 9 2 9 9 2 7

This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, Free Radical Biology & Medicine. The papers in this Forum (or Symposium-in-print) spanned seven issues of the journal, over many months. This is the first time that all of these expert contributions are presented in one place.Reliable methods for measuring OSS in organisms are essential. These would, amongst other things, offer applications as early warning signals for cancer and heart disease - eventually giving a range of measurable oxidation products best related to any given disease state.Additional observations relevant to OSS include: how much do measures of OSS vary in a group of humans? Does OSS decrease as a result of life-change factors and does it increase with age? With disease? With stress? Can a non-invasive, reliable, reputable measure of OSS be identified?This informative book provides the reader with the latest status of studies into OSS, currently used examples of BOSS, and answers to at least some of the questions posed above.

Free Radical Damage and its Control

1st Edition
Volume 28
February 9, 1994
C.A. Rice-Evans + 1 more
English
eBook
9 7 8 0 0 8 0 8 6 0 8 8 6

This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. This and many other such aspects are presented clearly and in depth.The development of antioxidant drugs depends on the understanding of the mechanisms underlying the generation of excessive free radicals in vivo, the factors controlling their release and the site of their action. This excellent volume presents an up-to-date account of the current state of knowledge in these areas.

Techniques in Free Radical Research

1st Edition
Volume 22
December 11, 1991
A.T. Diplock + 2 more
English
eBook
9 7 8 0 0 8 0 8 5 8 9 1 3

Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ESR is the only technique which has the potential for direct detection of radicals but in biological systems even these must be trapped by a spin-trapping agent. Thus most investigations involve recognition of indicators of the presence of radicals in vivo or "FOOTPRINTS" of radical-mediated damage. Techniques in Free Radical Research assembles and critically assesses the most relevant and reliable experimental approaches used towards the measurement of radicals and radical-mediated damage in chemical systems, in cells and in tissues under the following six headings: a) Footprints of DNA damage, b) Footprints of protein damage, c) Footprints of lipid peroxidation, d) Footprints of antioxidant consumption, e) Footprints via indirect radical assays, and f) Footprints via the availability of transition metal complexes.

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health

Books in Free radicals

Reactive Species Detection in Biology

Nitric Oxide

Nitric Oxide

Nitric Oxide, Part F

Oxidative Stress and Neurodegenerative Disorders

Energy Metabolism and Lifespan Determination

Bio-Assays for Oxidative Stress Status

Free Radical Damage and its Control

Techniques in Free Radical Research