Books in Biochemistry biophysics

Lipid Analysis

4th Edition
January 10, 2010
W. W. Christie + 1 more
English
Paperback
9 7 8 0 0 8 1 0 1 4 6 5 3

This well-known and highly successful book was first published in 1973 and has been completely re-written in subsequent editions (published in 1982 and 2003). This new Fourth Edition has become necessary because of the pace of developments in mass spectrometry of intact lipids, which has given recognition of lipid analysis and ‘lipidomics’ as a distinct science. To bring the book up to date with these developments, author William W. Christie is joined by co-author Xianlin Han. Although devoting considerable space to mass spectrometry and lipidomics, Lipid analysis remains a practical guide, in one volume, to the complexities of the analysis of lipids. As in past editions, it is designed to act as a primary source, of value at the laboratory bench rather than residing on a library shelf.Lipid analysis deals with the isolation, separation, identification and structural analysis of glycerolipids, including triacylglycerols, phospholipids, sphingolipids, and the various hydrolysis products of these. The chapters follow a logical sequence from the extraction of lipids to the isolation and characterization of particular lipid classes and of molecular species of each, and to the mass spectrometric analysis of lipids and lipidomics.The new influence of mass spectrometry is due mainly to the development of electrospray ionization (ESI) and matrix-assisted laser desorption/ionizatio... (MALDI). Most emphasis in this book is placed on ESI, which is enabling structural characterization of different lipid classes and the identification of novel lipids and their molecular species.

Advances in Protein Chemistry and Structural Biology

1st Edition
Volume 78
November 26, 2009
David S. Eisenberg + 1 more
English
Hardback
9 7 8 0 1 2 3 7 4 8 2 7 0
eBook
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Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. This eclectic volume features articles on a variety of topical subjects.

Cilia: Model Organisms and Intraflagellar Transport

1st Edition
Volume 93
November 23, 2009
Stephen M. King + 1 more
English
Hardback
9 7 8 0 1 2 3 8 1 3 7 7 0
eBook
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Cilia are highly conserved organelles that serve motile functions, sensory functions, or both. These organelles power cell movement, generate fluid flow in various organs, act as sensors of the extracellular environment and have been modified for various specialized tasks such as light reception and smell. Defects in these ubiquitous organelles lead to a broad array of human genetic disorders that range from polycystic kidney disease, retinal degeneration, epilepsy and infertility to developmental defects such as situs inversus and polydactyly. This volume is the third in a three-part series on cilia that focuses on the use of model organisms to gain insight into ciliary function and on the process of intraflagellar transport that is essential for the assembly and maintenance of ciliary structures.

Guide to Protein Purification

2nd Edition
Volume 436
November 19, 2009
Richard R Burgess + 1 more
English
Paperback
9 7 8 0 1 2 3 7 4 9 7 8 9

Guide to Protein Purification, Second Edition provides a complete update to existing methods in the field, reflecting the enormous advances made in the last two decades. In particular, proteomics, mass spectrometry, and DNA technology have revolutionized the field since the first edition’s publication but through all of the advancements, the purification of proteins is still an indispensable first step in understanding their function. This volume examines the most reliable, robust methods for researchers in biochemistry, molecular and cell biology, genetics, pharmacology, biotechnology and sets a standard for best practices in the field. It relates how these traditional and new cutting-edge methods connect to the explosive advancements in the field. This "Guide to" gives imminently practical advice in order to avoid costly mistakes in choosing a method and brings in perspective from the premier researchers while it presents a comprehensive overview of the field today.

Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part A

1st Edition
Volume 468
November 16, 2009
Daniel Herschlag
English
Hardback
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eBook
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This MIE volume provides laboratory techniques that aim to predict the structure of a protein which can have tremendous implications ranging from drug design, to cellular pathways and their dynamics, to viral entry into cells.

Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part B

1st Edition
Volume 469
November 16, 2009
Daniel Herschlag
English
Hardback
9 7 8 0 1 2 3 8 0 9 2 2 3
eBook
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Biothermodynamics, Part B

1st Edition
Volume 466
November 11, 2009
Michael L. Johnson + 2 more
English
Hardback
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eBook
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The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.

Liposomes, Part G

1st Edition
Volume 465
November 7, 2009
Nejat Duzgunes
English
Hardback
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eBook
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Liposomes are cellular structures made up of lipid molecules, which are water insoluble organic molecules and the basis of biological membranes. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies. Liposomes Part F is a continuation of previous MIE Liposome volumes A through E.

Molecular Diagnostics

1st Edition
November 6, 2009
Wayne W. Grody + 3 more
English
Hardback
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eBook
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Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. Molecular Diagnostics provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting.

Liposomes, Part F

1st Edition
Volume 464
November 6, 2009
Nejat Duzgunes
English
Hardback
9 7 8 0 1 2 3 7 4 9 6 9 7
eBook
9 7 8 0 0 8 0 9 6 1 0 2 6

Related subjects

Bioenergetics

Biological transport

Biomembranes

Carbohydrate biochemistry

Clinical biochemistry

Comparative biochemistry

Enzymology

Free radicals

Lipids and lipid metabolism

Methodology techniques and instruments in biochemistry

Nucleic acids

Peptides amino acids amines amides

Physical biochemistry

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health