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  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 6
    • Norman J. Lass
    • English
    Speech and Language: Volume 6, Advances in Basic Research and Practice is a collection of papers that discusses pathology, theories, and clinical issues related to language and speech. Some papers describe auditory discrimination and intervention techniques for articulatory defects, assessment of auditory disorders, phonological systems of deaf speakers, as well as speech and language characteristics of aging persons. Other papers discuss issues in language and cognitive assessment of black children, distortions of the supralaryngeal vocal tract, the structure of the human tongue, transformation of the acoustic signal into speech, and methods to estimate glottal volume velocity waveform properties. One paper suggests guidelines that investigators should be aware of before giving any speech discriminating tests. These guidelines include the following: use of age appropriate tests, use of culturally unbiased tests, adaption of intrapersonal testing procedures, and utilization of recorded stimulus presentation. Another paper reviews auditory processing deficits associated with brain damage and the considerations applicable to the assessment of such disorders. It also suggests treatment planning. One paper concludes that the phonological structure of a fluent speech requires that the listener employ higher level sources of knowledge while making phonetic decisions. Linguists, speech pathologists., psychologists, speech therapists, neurologists, neuropsychologists, and neurolinguists will find the collection highly relevant.
  • Developments in Statistics

    • 1st Edition
    • Volume 4
    • Paruchuri R. Krishnaiah
    • English
    Developments in Statistics, Volume 4 reviews developments in the theory and applications of statistics, covering topics such as time series, identifiability and model selection, and missing data. The application of structured exploratory data analysis to human genetics, specifically, the mode of inheritance, is also considered. Comprised of four chapters, this volume begins with an introduction to spectrum parameter estimation in time series analysis, restricting the discussion to the simplest univariate (that is, scalar) real-valued time series X(t). An accurate formulation of the general problem is presented. The accuracy of different consistent estimates obtained for large but fixed values of T (maximum likelihood estimates, Whittle's estimates, and simplified asymptotically efficient estimates) is also compared. The next chapter deals with identifiability and modeling in econometrics, focusing on the theoretical framework relating realization theory, identification, and parametrization. The realization theory is illustrated on various levels of generality by means of examples related to econometrics, along with some advanced applications of system theory. The book also examines inference on parameters of multivariate normal populations when some data are missing before concluding with an evaluation of structured exploratory data as applied to the study of the mode of inheritance. This monograph will be of interest to students and practitioners of statistics.
  • Advances in Steroid Biochemistry and Pharmacology

    • 1st Edition
    • M. H. Briggs + 1 more
    • English
    Advances in Steroid Biochemistry and Pharmacology, Volume 4 provides information pertinent to the fundamental aspects of steroid biochemistry and pharmacology. This book covers a variety of topics, including cellular biochemistry, pituitary hormones, corticosteroids, and steroid hormones. Organized into seven chapters, this volume begins with an overview of the potential effects of steroids on cellular biochemistry. This text then examines the development of sleep-monitoring methods, together with methods of plasma sampling that enable very frequent specimen to be taken without disturbing the subject. Other chapters consider the usefulness of sleep-related growth hormone release in diagnosis in both children and adult. This book discusses as well the versatile effect of corticosteroids on the cellular components of the connective tissue. The final chapter deals with the functioning of the adrenal cortex and its control by adrenocorticotropic hormone (ACTH). This book is a valuable resource for biochemists, histochemists, biologists, pharmacologists, clinicians, and experimental endocrinologists.
  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 16
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 16 considers the advances in the general area of cellular regulation. This book discusses the subcellular distribution of hexokinase in brain homogenates and experimental evidence for bound hexokinase as a compartmental control point. The enzymology and biologic significance of cytochrome c methylation, polyaromatic-biosynt... multienzyme system, and proteolytic modulation of gene expression in sporulation are also elaborated. This text likewise covers the occurrence of cyclic nucleotide-synthesiz... and -degrading enzymes in the mammalian brain and calcium ion as a positive effector of oocyte maturation. This volume is beneficial to biologists and researchers conducting work on the basic mechanisms involved in the regulation of diverse cellular activities.
  • Advances in Lipid Research

    • 1st Edition
    • Volume 15
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 15 is a four-chapter text that covers important aspects of lipid chemistry, including biomembranes and fungal lipids. The first chapter is devoted to the long-range order in biomembranes. This chapter presents evidence that the proteins and lipids of biological membranes are partitioned into functional and structural aggregates in the plane of the membrane. The second chapter surveys the pharmacology and toxicology of steroids and related compounds. This chapter also provides the methodology, physiologic and transport mechanisms, and effects on the central nervous system. The third chapter explores all aspects of lipid composition of all classes of fungi. This chapter also discusses the intracellular distribution and biosynthesis of the lipid components of fungi. The fourth chapter considers the biochemistry of plant sterols, including structure, stereochemistry, biosynthesis, metabolism, and function. This book will be of value to lipid chemists, biochemists, and researchers.
  • Molecular Mechanisms of Immunological Self-Recognition

    • 1st Edition
    • Frederick Alt + 1 more
    • English
    Molecular Mechanisms of Immunological Self-Recognition covers the understanding of immunological self-recognition. The introductory chapter of the book summarizes the dawn of the insight into immunological tolerance, and provides an overview of research on the underlying mechanisms. The book addresses the developments in the molecular mechanisms of B and T cell tolerance and describes the failure of tolerance in autoimmunity. The text concludes by furnishing orienting perspectives and highlighting new information presented. The novel findings characterized as impressive advances pertain to the areas of B cell development and the generation of molecular diversity; V gene usage, especially from transgenes, in positive and negative thymic selection; the handling of positive and negative signals by T and B cells; anergy in postthymic T cells; the design of peptide-based therapy for autoimmune diseases; and the design of therapy with the aid of monoclonal antibodies. Immunologists will find the text useful.
  • Laminar Flow Forced Convection in Ducts

    A Source Book for Compact Heat Exchanger Analytical Data
    • 1st Edition
    • R. K. Shah + 1 more
    • Thomas F. Irvine + 1 more
    • English
    Laminar Flow Forced Convection in Ducts is a sourcebook for compact heat exchanger analytical data. This book describes the analytical solutions for laminar fluid flow and forced convection heat transfer in circular and noncircular pipes, including applicable differential equations and boundary conditions involving velocity and temperature problems of fluid flow. The book also discusses fluid flow—how much power is required to pump fluids through the heat exchanger, as well as the heat transfer—the determination of q" distribution, and the temperature of fluid and walls. The text also analyzes the coolant or heat transfer fluid flows in a nuclear power reactor composed of a bundle of circular section fuel rods located inside a round tube. R.A. Axford addresses fluid flow and heat transfers results for the rod bundle geometry in "Heat Transfer in Rod Bundles." The book also provides an overview and guidelines that can be used for the designer and the applied mathematician. This book is suitable for engineers working in electronics, aerospace, instrumentation, and biomechanics that use cooling or heating exchanges or solar collection systems.
  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 1
    • Norman J. Lass
    • English
    Speech and Language: Volume 1, Advances in Basic Research and Practice is a compendium of papers that discusses the processes and pathologies of, as well as applies theories and clinical issues to, speech and language. Some papers discuss perception of speech in early infancy, the problems faced by speech clinicians, and the anatomy of the perioral motor system. Based on data compiled on the infant's perception of speech sounds, one paper notes that human infants discriminate depending on fine temporal and frequency changes in a complex auditory array. Infants also show perceptual constraints while listening to speech characterized as adult- like; they are also predisposed to perceive certain speech-sound categories such as vowel and fricative categories. One paper examines the suggestion of Kent (1976) that "acoustic characteristics of children's speech...hold the promise of sensitive methods for the study of speech maturation and developmental disorders." This investigation involves the following: the recent attempts at multidimensional analyses of speech and perception; a measure of perceptual contrast; and results of feature comparison efforts. The compendium is well suited for linguists, ethnologists, psychologists, and researchers whose works involve linguistics, language learning, communications, and syntax.
  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 9
    • Norman J. Lass
    • English
    Speech and Language: Advances in Basic Research and Practice, Volume 9 is a collection of contributions that discuss a broad range of topics on speech and language processes and pathologies. This volume contains seven contributions covering a wide array of topics on speech and language. It covers topics on speech development and production in normal and hearing-impaired speakers; integrated speech and language instruction for the hearing-impaired adolescent; and laryngectomee rehabilitation. Also discussed are subjects on sensory and motor changes during development and aging; the phonetic structure of errors in the perception of fluent speech; and the multiple meanings of phoneme and their confusions. Linguists, speech pathologists, and researchers on language development will find the book very insightful and informative.
  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 19
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 19 analyzes the advances in the general area of cellular regulation. This book discusses the evidence indicating that synthesis of the histidine enzymes is regulated and drugs affecting ribonucleotide reductase. The analogy principle in comparative biochemistry of allosteric regulation of metabolism, steady-state model of glucose metabolism in adipose tissue, and sensitivity of enzyme activity to changing ion concentrations are also elaborated. This publication likewise covers the cAMP-dependent protein kinases of nervous tissue and amino acid sequences of IGF I and II. This volume is a good reference for biologists and researchers conducting work on the basic mechanisms involved in the regulation of diverse cellular activities.