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    • History of Programming Languages

      • 1st Edition
      • May 27, 2014
      • Richard L. Wexelblat
      • English
      • eBook
        9 7 8 1 4 8 3 2 6 6 1 6 9
      History of Programming Languages presents information pertinent to the technical aspects of the language design and creation. This book provides an understanding of the processes of language design as related to the environment in which languages are developed and the knowledge base available to the originators. Organized into 14 sections encompassing 77 chapters, this book begins with an overview of the programming techniques to use to help the system produce efficient programs. This text then discusses how to use parentheses to help the system identify identical subexpressions within an expression and thereby eliminate their duplicate calculation. Other chapters consider FORTRAN programming techniques needed to produce optimum object programs. This book discusses as well the developments leading to ALGOL 60. The final chapter presents the biography of Adin D. Falkoff. This book is a valuable resource for graduate students, practitioners, historians, statisticians, mathematicians, programmers, as well as computer scientists and specialists.

    • Mathematical Software

      • 1st Edition
      • May 27, 2014
      • John R. Rice
      • English
      • eBook
        9 7 8 1 4 8 3 2 6 7 0 0 5
      Mathematical Software deals with software designed for mathematical applications such as Fortran, CADRE, SQUARS, and DESUB. The distribution and sources of mathematical software are discussed, along with number representation and significance monitoring. User-modifiable software and non-standard arithmetic programs are also considered. Comprised of nine chapters, this volume begins with a historical background in the form of a chronological list of events that trace the development of computing in general and mathematical software in particular. The next chapter examines where and how mathematical software is being created and how it is being disseminated to eventual consumers. A number of important shortcomings are identified. The future of mathematical software and the challenges facing mathematical software are then discussed. Subsequent chapters focus on the point of view of people outside the professional community of mathematical software; the monitoring of significance in computation and its relation to number representation; libraries of mathematical software; and the automation of numerical analysis. Eleven algorithms for numerical quadrature are also compared. This book should be of considerable interest to students and specialists in the fields of mathematics and computer science.

    • Nonlinear Equations in Abstract Spaces

      • 1st Edition
      • May 27, 2014
      • V. Lakshmikantham
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 2 2 0 0
      • eBook
        9 7 8 1 4 8 3 2 7 2 1 0 8
      Many problems in partial differential equations which arise from physical models can be considered as ordinary differential equations in appropriate infinite dimensional spaces, for which elegant theories and powerful techniques have recently been developed. This book gives a detailed account of the current state of the theory of nonlinear differential equations in a Banach space, and discusses existence theory for differential equations with continuous and discontinuous right-hand sides. Of special importance is the first systematic presentation of the very important and complex theory of multivalued discontinuous differential equations.

    • Rodents

      • 1st Edition
      • May 27, 2014
      • Edwin J. Atencio + 2 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 8 2 1 9 0

    • Rare Diseases and Orphan Drugs

      • 1st Edition
      • May 26, 2014
      • Jules J. Berman
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 2 7 6 3
      • Hardback
        9 7 8 0 1 2 4 1 9 9 8 8 0
      • eBook
        9 7 8 0 1 2 4 2 0 0 0 9 8
      Rare Diseases and Orphan Drugs shows that much of what we now know about common diseases has been achieved by studying rare diseases. It proposes that future advances in the prevention, diagnosis, and treatment of common diseases will come as a consequence of our accelerating progress in the field of rare diseases. Understanding the complex steps in the development of common diseases, such as cancer, cardiovascular disease, and metabolic diseases, has proven a difficult problem. Rare diseases, however, are often caused by aberrations of a single gene. In rare diseases, we may study how specific genetic defects can trigger a series of events that lead to the expression of a particular disease. Often, the disease process manifested in a certain rare disease is strikingly similar to the disease process observed in a common disease. This work ties the lessons learned about rare diseases to our understanding of common ones. Chapters covering the number of common diseases are minimized, while rare diseases are introduced as single diseases or as members of diseases classes. After reading this book, readers will appreciate how further research into the rare diseases may lead to new methods for preventing, diagnosing, and treating all diseases, rare or common.

    • Advances in Cephalopod Science: Biology, Ecology, Cultivation and Fisheries

      • 1st Edition
      • Volume 67
      • May 26, 2014
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 2 8 7 2
      • eBook
        9 7 8 0 1 2 8 0 0 3 2 0 6
      Advances in Cephalopod Science: Biology, Ecology, Cultivation and Fisheries—volume 67 in the Advances in Marine Biology series—addresses major themes of growing research interest in the field of cephalopod research. The book is composed of four chapters incorporating the latest advances in biology, ecology, life cycles, cultivation, and fisheries of cephalopods. Each chapter is written by a team of internationally recognized authorities to reflect recent findings and understanding. The book represents a breakthrough contribution to the field of cephalopod science. Advances in Marine Biology was first published in 1963 under the founding editorship of Sir Frederick S. Russell, FRS. Now edited by Michael P. Lesser, with an internationally renowned editorial board, the serial publishes in-depth and up-to-date reviews on a wide range of topics that appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology, and biological oceanography. Eclectic volumes in the series are supplemented by thematic volumes on such topics as the biology of calanoid copepods.

    • Stem Cells

      • 2nd Edition
      • May 23, 2014
      • Christine L. Mummery + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 5 5 1 4
      • eBook
        9 7 8 0 1 2 4 1 1 5 6 7 5
      The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies.

    • Mathematics for Physical Science and Engineering

      • 1st Edition
      • May 23, 2014
      • Frank E. Harris
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 0 0 0 6
      • eBook
        9 7 8 0 1 2 8 0 1 0 4 9 5
      Mathematics for Physical Science and Engineering is a complete text in mathematics for physical science that includes the use of symbolic computation to illustrate the mathematical concepts and enable the solution of a broader range of practical problems. This book enables professionals to connect their knowledge of mathematics to either or both of the symbolic languages Maple and Mathematica. The book begins by introducing the reader to symbolic computation and how it can be applied to solve a broad range of practical problems. Chapters cover topics that include: infinite series; complex numbers and functions; vectors and matrices; vector analysis; tensor analysis; ordinary differential equations; general vector spaces; Fourier series; partial differential equations; complex variable theory; and probability and statistics. Each important concept is clarified to students through the use of a simple example and often an illustration. This book is an ideal reference for upper level undergraduates in physical chemistry, physics, engineering, and advanced/applied mathematics courses. It will also appeal to graduate physicists, engineers and related specialties seeking to address practical problems in physical science.

    • From Molecules to Networks

      • 3rd Edition
      • May 23, 2014
      • John H. Byrne + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 7 1 7 9 1
      • eBook
        9 7 8 0 1 2 3 9 8 2 6 7 4
      An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. The third edition of From Molecules to Networks provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells. In keeping with previous editions, the unique content focus on cellular and molecular neurobiology and related computational neuroscience is maintained and enhanced. All chapters have been thoroughly revised for this third edition to reflect the significant advances of the past five years. The new edition expands on the network aspects of cellular neurobiology by adding new coverage of specific research methods (e.g., patch-clamp electrophysiology, including applications for ion channel function and transmitter release; ligand binding; structural methods such as x-ray crystallography). Written and edited by leading experts in the field, the third edition completely and comprehensively updates all chapters of this unique textbook and insures that all references to primary research represent the latest results.

    • Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism

      • 1st Edition
      • Volume 542
      • May 23, 2014
      • English
      • Hardback
        9 7 8 0 1 2 4 1 6 6 1 8 9
      • eBook
        9 7 8 0 1 2 4 1 6 6 5 7 8
      Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation.

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