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Elsevier

Academic Press

  • Control and Dynamic Systems

    Advances in Theory and Applications
    • 1st Edition
    • Volume 12
    • C. T. Leondes
    • English
    Control and Dynamic Systems: Advances in Theory and Applications reviews progress in the field of control and dynamic systems theory and applications, with emphasis on filtering and stochastic control in dynamic systems. Topics include linear and nonlinear filtering techniques; concepts and methods in stochastic control; and discrete-time optical stochastic observers. The theory of disturbance-accommod... controllers is also presented. Comprised of nine chapters, this volume begins with an overview of filtering and stochastic control in dynamic systems, followed by a discussion on linear and nonlinear filtering techniques. The reader is then introduced to concepts and methods in stochastic control, as well as the innovations process and its applications to sensitivity analysis and system identification. Subsequent chapters focus on the status of observer theory and its major results as applied to discrete-time linear systems; the properties of the class of discrete-time Riccati equations that arise in the filtering problem; and the theory of disturbance-accommod... controllers. The identification of noise characteristics in a Kalman filter and estimation of adaptive minimum variance in discrete-time linear systems round out the book. This monograph will be useful to practicing technologists and research workers interested in filtering and stochastic control in dynamic systems.

  • Molecular Genetics Medicine

    • 1st Edition
    • Volume 4
    • Theodore Friedmann
    • English
    Continuing to keep pace with progress in human molecular genetics, Volume 4 of Molecular Genetic Medicine reviews five new areas of critical importance. Chapter 1 reviews the molecular mechanisms that have beenunraveled in the pathogenesis of eye diseases. The second chapter explains the remarkable new principle if genomic imprinting, or epigenetic modification imposed by parental history. Chapter 3 describes the etiology of amyotrophic lateral sclerosis, or Lou Gehrig's Disease, as effected by superdioxide dismutase function and neuron degeneration. The fourth chapter covers the normal and aberrant functions of peroxisomes, now implicated in many diseases, most notably adrenoleukodystrophy... publicized widelyby the"cure"called Lorenzo's oil. The final chapter summarizes recombination techniques that permit functional new genetic material to be introduced into, and subsequently transmitted through, the germ line of mammalian cells. These amazing methods arehaving profound impacts on medicine and on concepts of the study of normal human development and disease.

  • Molecular Basis of Mitochondrial Pathology

    • 1st Edition
    • Volume 17
    • C. P. Lee
    • English
    The field of mitochondrial diseases is currently one of the rapidly growing fields of research in cell and molecular biology. This volume encompasses the latest development in this field of research. The chapters cover topics in a wide range of disciplines including biophysics, biochemistry, cell and molecular biology, molecular genetics, and clinical medicine.

  • Essays in Biochemistry

    • 1st Edition
    • K. F. Tipton
    • English
    Essays in Biochemistry, Volume 25 provides information on the developments in the continually changing field of biochemistry. Each chapter of the book is written by an expert on the area of research. The volume contains contributions that deal with such topics as intracellular protein degradation; the metabolic heterogeneity of liver parenchymal cells; and the biochemistry of ethanol metabolism and the pathogenesis of alcoholic liver disease (ALD). Biochemistry and neurochemistry in the 1800 and their origins in comparative animal chemistry is discussed extensively in the final chapter. Biochemists will find the book very informative.

  • Drug Design

    • 1st Edition
    • Volume 9
    • BAREHAM BAREHAM J
    • English
    Drug Design, Volume IX examines various aspects of drug design and covers topics ranging from the consequences of the Hansch paradigm for the pharmaceutical industry to the Masca model of pharmacochemistry. A physicochemical basis for the design of orally active prodrugs is also considered, along with the use of interactive graphics in medicinal chemistry. Comprised of seven chapters, this volume begins with a discussion on efforts to avoid toxicity, not only of drugs, pesticides, and food additives but also of chemicals in general. The reader is then introduced to various aspects of the development of bioactive agents, including the optimization of existing agents by the design of more efficient prodrugs. Other chapters focus on Hansch's paradigm and its application to industrial practice; the application of multivariate statistics to pharmacochemistry; a logico-structural approach to computer-assisted drug design; and spatial arrangements in bioactive molecules. This book will be of interest to pharmacologists, chemists, and those involved in drug design.

  • MicroRNA in Regenerative Medicine

    • 1st Edition
    • Chandan K. Sen
    • English
    This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational application, they point to the current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA across repair and regeneration, and special coverage of methodologies and interventions as they point towards organ and tissue engineering

  • Energy Storage Devices for Electronic Systems

    Rechargeable Batteries and Supercapacitors
    • 1st Edition
    • Nihal Kularatna
    • English
    Energy storage devices are a crucial area of research and development across many engineering disciplines and industries. While batteries provide the significant advantage of high energy density, their limited life cycles, disposal challenges and charge and discharge management constraints undercut their effectiveness in certain applications. Compared to electrochemical cells, supercapacitors are charge-storage devices with much longer life cycles, yet they have traditionally been hobbled by limited DC voltage capabilities and energy density. However, recent advances are improving these issues. This book provides the opportunity to expand your knowledge of innovative supercapacitor applications, comparing them to other commonly used energy storage devices. It will strengthen your understanding of energy storage from a practical, applications-based point-of-view, without requiring detailed examination of underlying electrochemical equations. No matter what your field, you will find inspiration and guidance in the cutting-edge advances in energy storage devices in this book.

  • Advances in Heat Transfer

    • 1st Edition
    • Volume 46
    • Ephraim M. Sparrow + 3 more
    • English
    Advances in Heat Transfer fills the information gap between regularly scheduled journals and university-level textbooks by providing in-depth review articles over a broader scope than in journals or texts. The articles, which serve as a broad review for experts in the field, will also be of great interest to non-specialists who need to keep up-to-date with the results of the latest research. This serial is essential reading for all mechanical, chemical and industrial engineers working in the field of heat transfer, graduate schools or industry.

  • Principles of Financial Engineering

    • 3rd Edition
    • Robert Kosowski + 1 more
    • English
    Principles of Financial Engineering, Third Edition, is a highly acclaimed text on the fast-paced and complex subject of financial engineering. This updated edition describes the "engineering" elements of financial engineering instead of the mathematics underlying it. It shows how to use financial tools to accomplish a goal rather than describing the tools themselves. It lays emphasis on the engineering aspects of derivatives (how to create them) rather than their pricing (how they act) in relation to other instruments, the financial markets, and financial market practices. This volume explains ways to create financial tools and how the tools work together to achieve specific goals. Applications are illustrated using real-world examples. It presents three new chapters on financial engineering in topics ranging from commodity markets to financial engineering applications in hedge fund strategies, correlation swaps, structural models of default, capital structure arbitrage, contingent convertibles, and how to incorporate counterparty risk into derivatives pricing. Poised midway between intuition, actual events, and financial mathematics, this book can be used to solve problems in risk management, taxation, regulation, and above all, pricing. A solutions manual enhances the text by presenting additional cases and solutions to exercises. This latest edition of Principles of Financial Engineering is ideal for financial engineers, quantitative analysts in banks and investment houses, and other financial industry professionals. It is also highly recommended to graduate students in financial engineering and financial mathematics programs.

  • Human Physiology in Extreme Environments

    • 1st Edition
    • Hanns-Christian Gunga
    • English
    Human Physiology in Extreme Environments is the one publication that offers how human biology and physiology is affected by extreme environments while highlighting technological innovations that allow us to adapt and regulate environments. Covering a broad range of extreme environments, including high altitude, underwater, tropical climates, and desert and arctic climates as well as space travel, this book will include case studies for practical application. Graduate students, medical students and researchers will find Human Physiology in Extreme Environments an interesting, informative and useful resource for human physiology, environmental physiology and medical studies.

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