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Academic Press

Gene Activity in Early Development
1st Edition
Eric H. Davidson
English
Gene Activity in Early Development reviews the state of knowledge regarding genomic function in the programming and operation of what Bonnet, in 1762, described as "the miracle of epigenesis." The book is divided into four sections. Section I is concerned with gene activity in early embryogenesis, with the time of onset and the nature of embryo genome control, and with recent attempts to analyze the shifting patterns of gene expression as development proceeds. Section II reviews various classic and recent studies relevant to the phenomenon of cytoplasmic localization of morphogenetic potential and discusses the significance, from a contemporary vantage point, of this often neglected area of developmental biology. Section III deals with genomic function in oogenesis, beginning with a general survey of what could be described loosely as the natural history of the oocyte nucleus, and proceeding to current attempts to understand the character and the ultimate function of the oocyte gene products. Section IV discusses various aspects of the general problem of gene regulation in animal cells.
Decision Processes in Visual Perception
1st Edition
D. Vickers
Edward C. Carterette + 1 more
English
Decision Processes in Visual Perception explores the relationships between the organization of a complex visual pattern by the perception system and the molecular activity involved in the discrimination of differences in magnitude or intensity between two stimulus elements. The text discusses the basic principles of discrimination, identification, and self-regulation of the perception system; demonstrates how adaptive decision modules emerge from multiple constraints; shows how combinations of simple decisions lead to complex judgmental tasks; and synthesizes traditional approaches to perception in order to clarify the crucial and pervasive role of these modules in the overall activity of perceptual organization. Psychologists, neuroscientists, molecular biologists, and physiologists will find the book invaluable.
Current Topics in Bioenergetics
Volume 13
1st Edition
C. P. Lee
English
Current Topics in Bioenergetics, Volume 13 presents the biophysical and biochemical approaches that are valuable in some systems and that may be readily be applied to others. This book discusses the function and structure relationship of energy-transducing membranes that has played an essential role in the progress and development in the field of bioenergetics. Organized into six chapters, this volume begins with an overview of the bioenergetics processes that require a molecular description of the structure and reaction mechanisms of the individual energy-transducing catalysts. This text then provides an understanding to the methodology for initiation of an electron paramagnetic resonance (EPR) investigation in this field of research. This book discusses as well the developments in spin label EPR techniques. The final chapter deals with immunological techniques that are used for studying the biochemistry and molecular biology of membrane proteins. This book is a valuable resource for physiologists, biologists, and biochemists.
Electron and Positron Spectroscopies in Materials Science and Engineering
Materials Science and Technology
1st Edition
Otto Buck + 2 more
English
Electron and Positron Spectroscopies in Materials Science and Engineering presents the advances and limitations of instrumentations for surface and interface probing useful to metallurgical applications. It discusses the Auger electron spectroscopy and electron spectroscopy for chemical analysis. It addresses the means to determine the chemistry of the surface. Some of the topics covered in the book are the exo-electron emission; positron annihilation; extended x-ray absorption fine structure; high resolution electron microscopy; uniaxial monotonic deformation-induced dislocation substructure; and analytical electron microscopy. The mechanistic basis for exo-electron spectroscopy is covered. The correlation of fatigue and photoyield are discussed. The text describes the tribostimulated emission. A study of the quantitative measurement of fatigue damage is presented. A chapter is devoted to the fracture of oxide films on aluminium. Another section focuses on the positron annihilation experimental details and the creep-induced dislocation substructure. The book can provide useful information to scientists, engineers, students, and researchers.
Speech and Language
Advances in Basic Research and Practice
1st Edition
Volume 9
Norman J. Lass
English
Speech and Language: Advances in Basic Research and Practice, Volume 9 is a collection of contributions that discuss a broad range of topics on speech and language processes and pathologies. This volume contains seven contributions covering a wide array of topics on speech and language. It covers topics on speech development and production in normal and hearing-impaired speakers; integrated speech and language instruction for the hearing-impaired adolescent; and laryngectomee rehabilitation. Also discussed are subjects on sensory and motor changes during development and aging; the phonetic structure of errors in the perception of fluent speech; and the multiple meanings of phoneme and their confusions. Linguists, speech pathologists, and researchers on language development will find the book very insightful and informative.
Enzyme Catalysis and Control
1st Edition
Volume 24
Marlene Deluca + 2 more
English
Current Topics in Cellular Regulation: Volume 24, Enzyme Catalysis and Control is a compendium of papers that discusses phosphoryl transfer reactions, the role of water on the free energy of hydrolysis of pyrophosphate, and the hormonal actions of vitamin D. Other papers describe the regulation lipid metabolism by a lipid-carrying protein, the GABA, and taurine enzymes in mammalian brain. One paper examines the role of vitamin D in the metabolism of cells, as well as in the whole animal. Upon absorption in the body, the vitamin undergoes various metabolic transformations before interacting with specific receptors, and then inducting the genome in the target tissues to generate biological and hormonal responses. Another paper notes the possibility of a genetic defect in cancer cells that results in the abnormal accumulation of sterol carrier protein (SCP) and cholesterol in vivo; and also in the inability to maintain levels of SCP or cholesterol in vitro. One paper shows that tartrate, or other organic acids, secreted into the medium by the penicillia keeps the pH in an optimal range for acid protease degradation of proteins and glycoproteins. This mechanism helps the fungus to survive in a nutrient environment (which is unbalanced with respect to an optimum C/N ratio and at a pH unfavorable to many bacteria and other life forms). Another paper proposes a model for the modulation of ATP synthetase activities and medium exchange reactions by energy input, substrate concentration, or others that affect the microenvironment of the enzyme under certain conditions. The compendium will prove beneficial to molecular biologists, general biologists, microbiologists, and biochemists.
Sex Chromosomes
1st Edition
Ursula Mittwoch
English
Sex Chromosomes focuses on the study of sex chromosomes, including human chromosomal abnormalities, behavior and characteristics of chromosomes, and cell division. The book first offers information on the chromosomal basis of sex determination, as well as development of the cell theory, mitosis, fertilization, meiosis, and discovery of sex chromosomes. The publication also ponders on the mitosis, meiosis, and formation of gametes. Discussions focus on the special characteristics of sex chromosomes, abnormalities of cell division, and sexual differentiation. The manuscript reviews sex chromosomes in plants, Drosophila, and Lepidoptera. The book also examines sex-chromosome mechanisms that differ the classic type; sex chromosomes in fishes, amphibia, reptiles, and birds; and sex chromosomes in man. Discussions focus on normal human sex chromosomes, Turner's syndrome, Klinefelter's syndrome, true hermaphrodites, testicular feminization, and pseudohermaphrodites... Sex chromosomes in mammals other than man, including monotremata, marsupialia, insectivora, rodentia, and carnivora, are discussed. The publication is a dependable reference for readers interested in the study of sex chromosomes.
The Structure of Mitochondria
1st Edition
E. A. Munn
English
The Structure of Mitochondria provides an extensive account of the structure of mitochondria. This book illustrates the variety of mitochondrial structure revealed by electron microscopy of intact cells. Organized into nine chapters, this book begins with an overview of the application of electron microscopy to the study of the structure of cells and their mitochondria. This text then explains the short-term changes of the type revealed by phase contrast microscopy of living cells. Other chapters consider the rationale behind the procedures generally employed for the isolation of mitochondria and other sub-cellular components. This book discusses as well the important component of mitochondria. The final chapter describes the interesting similarities of mitochondria, chloroplasts, and bacteria and the bearing these have on the concept about the way in which the relationships between mitochondria and the rest of the eukaryotic cell have evolved. This book is a valuable resource for biologists, physiologists, and bacteriologists.
Developments in Statistics
1st Edition
Volume 4
Paruchuri R. Krishnaiah
English
Developments in Statistics, Volume 4 reviews developments in the theory and applications of statistics, covering topics such as time series, identifiability and model selection, and missing data. The application of structured exploratory data analysis to human genetics, specifically, the mode of inheritance, is also considered. Comprised of four chapters, this volume begins with an introduction to spectrum parameter estimation in time series analysis, restricting the discussion to the simplest univariate (that is, scalar) real-valued time series X(t). An accurate formulation of the general problem is presented. The accuracy of different consistent estimates obtained for large but fixed values of T (maximum likelihood estimates, Whittle's estimates, and simplified asymptotically efficient estimates) is also compared. The next chapter deals with identifiability and modeling in econometrics, focusing on the theoretical framework relating realization theory, identification, and parametrization. The realization theory is illustrated on various levels of generality by means of examples related to econometrics, along with some advanced applications of system theory. The book also examines inference on parameters of multivariate normal populations when some data are missing before concluding with an evaluation of structured exploratory data as applied to the study of the mode of inheritance. This monograph will be of interest to students and practitioners of statistics.
Advances in Lipid Research
1st Edition
Volume 16
Rodolfo Paoletti + 1 more
English
Advances in Lipid Research, Volume 16 is a seven-chapter text that contains research studies on the chemistry and physiology of lipids. The introductory chapter reviews the metabolism of distinct molecular species of phospholipids. The succeeding chapters describe the relationship between fatty acid and immunity, as well as the influence of vitamin C on cholesterol metabolism, gallstone formation, and atheroschlerosis. These chapters also examine the possible link between vitamin C deficiency and lipid disorders. A chapter discusses the arterial enzymes of cholesteryl ester metabolism, specifically the synthesis and hydrolysis of cholesteryl esters under a variety of conditions. The remaining chapters consider the occurrence, characteristics, and factors affecting reaction of phospholipase D. Surveys of the certain aspects of prostaglandin metabolism and the effects of thyroid hormone on atherosclerosis are also provided in these chapters. This book will prove useful to lipid and enzyme chemists, biochemists, and researchers.

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