Skip to main content
Elsevier
View Cart

Academic Press

    • Pharmacology and Therapeutics of Constitutively Active Receptors

      • 1st Edition
      • Volume 70
      • June 11, 2014
      • Ya-Xiong Tao
      • English
      • Hardback
        9 7 8 0 1 2 4 1 7 1 9 7 8
      • eBook
        9 7 8 0 1 2 4 1 7 2 0 6 7
      Volume 70 of Advances in Pharmacology presents the pharmacology and therapeutics of constitutively active receptors. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists, and biochemists alike. Advances in Pharmacology provides a rich collection of reviews on timely topics. The series places emphasis on the molecular bases of drug action, both applied and experimental.

    • Towards Sustainable Road Transport

      • 1st Edition
      • June 11, 2014
      • Ronald M. Dell + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 4 0 4 6 1 6 0
      • eBook
        9 7 8 0 1 2 4 0 4 6 9 1 7
      Increasing pressure on global reserves of petroleum at a time of growing demand for personal transport in developing countries, together with concerns over atmospheric pollution and carbon dioxide emissions, are leading to a requirement for more sustainable forms of road transport. Major improvements in the efficiency of all types of road vehicles are called for, along with the use of fuels derived from alternative sources, or entirely new fuels. Towards Sustainable Road Transport first describes the evolution of vehicle designs and propulsion technologies over the past two centuries, before looking forward to possible new forms of energy to substitute for petroleum. The book also discusses the political and socio-economic drivers for change, investigates barriers to their broad implementation, and outlines the state-of-the-art of candidate power sources, advanced vehicle design, and associated infrastructure. The comprehensive technical informationsupplied by an expert author team ensures that Towards Sustainable Road Transport will provide readers with a clear understanding of the ongoing progress in this field and the challenges still to be faced.

    • Macroeconomics

      • 1st Edition
      • June 11, 2014
      • James D Gwartney + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 1 8 0 4 5
      Macroeconomics: Private and Public Choice discusses the principle of macroeconomics, particularly government expenditure, taxation, public choice theory, and labor markets. The book also covers aggregate supply, fiscal policy, inflation, unemployment, traditional Keynesian theory, low productivity, rapid inflation. The text explains international economics and comparative systems such as the export-import link, export taxes, and foreign finance. It analyzes the existence of trade barriers as being due to domestic protectionism policies, special interest nature of trade restrictions, and economic illiteracy. The book examines the economics of government failure, namely, the collective decision-making process as being both beneficial and limited of public sector economic action. Among the reasons cited for government failure are voter ignorance, inefficient public policy, existence of special interests, imprecise knowledge of consumer preferences, as well as government shortsightedness. The book also examines why government intervention in some activities can be beneficial, for example, weak market competition or monopoly, uninformed consumers, and when conditions of external benefits can be achieved. Economists, sociologists, professors in economics, or policy makers involved in economic and rural development will find the text valuable.

    • Advances in Parasitology

      • 1st Edition
      • Volume 85
      • June 10, 2014
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 1 8 2 0
      • eBook
        9 7 8 0 1 2 8 0 0 3 1 2 1
      First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies on parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on various topics, including control of human parasitic diseases and global mapping of infectious diseases. The 2012 impact factor is 3.778.

    • Cell-wide Metabolic Alterations Associated with Malignancy

      • 1st Edition
      • Volume 543
      • June 7, 2014
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 3 2 9 8
      • eBook
        9 7 8 0 1 2 8 0 1 4 8 3 7
      This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation.

    • Advances in Experimental Social Psychology

      • 1st Edition
      • Volume 50
      • June 6, 2014
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 2 8 4 1
      • eBook
        9 7 8 0 1 2 8 0 0 3 1 4 5
      Advances in Experimental Social Psychology continues to be one of the most sought after and most cited series in this field. Containing contributions of major empirical and theoretical interest, this series represents the best and the brightest in new research, theory, and practice in social psychology. The present volume, number 50, features articles on the evolution of human mating strategies, free will in social psychology, social psychology and the fight against AIDS, and more.

    • The Population Dynamics of the Mucajai Yanomama

      • 1st Edition
      • June 6, 2014
      • John Early
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 7 5 4 1
      • eBook
        9 7 8 0 3 2 3 1 6 0 8 2 7
      The Population Dynamics of the Mucajai Yanomama is an analysis of the Mucajai Yanomama, an Indian foraging/horticultur... group located in northern Brazil. The text is an investigation of the population dynamics of the Yanomama Indians, using methods of quantitative demography and qualitative ethnography. The timeline of text focuses from 1958 to 1987, from their first ever contact with representative of the ""outer world"". The book is divided into four major parts and comprised of a total of 10 chapters. Part One introduces the tribe of the Mucajai Yanomama and discusses their population dynamics, as well as provides an overview of postcontact period of 28 years. Part Two focuses on the demographic issues of the tribe. This part looks into variables, such as fertility, mortality, and migration, to understand factors such as cultural antecedents and age-sex structure. Part Three serves as a synthesis of the demographic variables and their relation to each other. The other issue synthesized in this part of the book is the impact of population structure to the cultural practices of the tribe. Lastly, Part Four provides the conclusion of the study and compares the results to other studies of Yanomama groups. The text is a helpful resource mostly to anthropologists and evolutionary demographers, but can also be a reference to anyone who studies population dynamics.

    • Biased Signaling in Physiology, Pharmacology and Therapeutics

      • 1st Edition
      • June 5, 2014
      • Brian J Arey
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 3 1 0 4
      • Hardback
        9 7 8 0 1 2 4 1 1 4 6 0 9
      • eBook
        9 7 8 0 1 2 4 1 1 5 0 7 1
      Biased Signaling in Physiology, Pharmacology and Therapeutics is a unique and essential reference for the scientific community concerning how conformational-depen... activation is a common phenomenon across many classes of receptors or signaling molecules. It discusses the role of conformational dynamics in leading to signaling bias across different classes of receptors and signaling molecules. By providing a broader view of signaling bias, this resource helps to explain common mechanisms shared across receptor classes and how this can be utilized to elucidate their cellular activity and better understand their therapeutic potential. Written for both new and established scientists in pharmacology, cell biology, biochemistry, and signal transduction, as well as physicians, this book clearly illustrates how biased receptor signaling can be utilized to develop and understand complex pharmacology. Chapters are each focused on a specific class of receptor or other important topic and make use of real-world examples illustrating how the latest research in signal transduction has led to a better understanding of pharmacology and cell biology. This structure creates a basis for understanding that physiological signalling bias has been selected by nature in order to provide complex and tissue- specific biological responses in the face of limited receptors and signaling pathways. This book provides a framework to reveal that these physiological mechanisms are not restricted to one receptor type or family and thus presents receptor signaling from a newer, more global perspective.

    • Celiac Disease and Gluten

      • 1st Edition
      • June 5, 2014
      • Peter Koehler + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 4 2 0 2 2 0 7
      • Paperback
        9 7 8 0 1 2 8 1 0 1 3 4 6
      • eBook
        9 7 8 0 1 2 7 9 9 9 2 6 5
      Celiac Disease and Gluten: Multidisciplinary Challenges and Opportunities is a unique reference work—the first to integrate the insights of the causes and effects of celiac disease from the chemistry of reaction-causing foods to the diagnosis, pathogenesis, and symptoms that lead to proper diagnoses and treatment. With an estimated three million people in the United States alone affected by celiac disease, an autoimmune digestive disease, only five percent are properly diagnosed. Drawing on the connection between foods containing gluten and the resulting symptoms, this resource offers distinctive information that directly explores and links food science, medical diagnostics, and treatment information. A helpful tool for researchers and medical practitioners alike, Celiac Disease and Gluten: Multidisciplinary Challenges and Opportunities helps refine research targets, and provides a comprehensive overview on the multidisciplinary approaches to all crucial aspects related to celiac disease.

    • Lymphokines

      • 1st Edition
      • June 5, 2014
      • Edgar Pick
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 2 1 5 6
      • eBook
        9 7 8 1 4 8 3 2 6 6 9 9 2
      Lymphokines: A Forum for Immunoregulatory Cell Products deals with immunoregulatory cell products that produce lymphokines. Topics covered include the purification and characterization of transfer factor; activation of cytotoxicity and/or suppressor activity in murine macrophages by lymphokines, lipopolysaccharide, and polyinosinic-polycyt... acid; and the role of clotting processes in the action of lymphokines on macrophages. A comparison of the immune-modulating effects of interferon and interferon inducers is also presented. Comprised of 13 chapters, this volume begins with a discussion on transfer factor and its ability to react specifically with antigens. The clinical uses of transfer factor are considered with special emphasis on its value as a prophylactic agent. The reader is then introduced to the subject of T cell regulation of the immunoglobulin E (IgE) response via potentiating and suppressor lymphokines, together with the possible clinical application of IgE suppressive factors in the treatment of atopic diseases. Subsequent chapters examine the evidence in favor of the existence of T cell-derived polyclonal B cell activator (PBA) playing a role in both normal antibody responses and autoimmune diseases; the role of suppressor T cells and the associated lymphokines in contact sensitivity in mice; and lymphokine action on macrophages. The book also analyzes the genetics of the response of human and mouse cells to interferons. This monograph will be helpful to practitioners and researchers in the fields of microbiology and immunology.

Browse by Publisher

Butterworth-Heinemann

Chandos

Elsevier

Morgan Kaufmann

Newnes

Syngress