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Elsevier

Academic Press

  • Advanced Cancer Therapeutics

    Strategies and Technologies for Targeted Drug Delivery
    • 1st Edition
    • Manish Kumar + 2 more
    • English
    Advanced Cancer Therapeutics: Strategies and Technologies for Targeted Drug Delivery explores the heterogeneity of tumors and microenvironmental factors that influence cancer treatment and contribute to drug resistance. The book discusses critical elements such as tumor stroma, vasculature, pH, hypoxia, and enzymatic activity that impact therapeutic efficacy. Sections cover advanced drug formulations, including supramolecular systems, metal-organic frameworks, and nanomedicine, focusing on their roles in selective drug delivery for early detection, diagnosis, and treatment of various cancers. In addition, it reviews the current status and future perspectives of these formulations, highlighting their potential to enhance therapeutic outcomes while minimizing side effects.Readers will also find discussions on the limitations of nanocarriers, along with regulatory and ethical considerations related to anticancer formulations. This resource is invaluable for researchers, clinicians, and students, offering insights into the latest advancements in drug delivery systems.

  • Politics, Practice, and Policy

    How to Get Things Done in Food and Nutrition, 10 Case Studies
    • 1st Edition
    • Eileen Kennedy
    • English
    Food and Nutrition Policy: 10 Case Studies for Developing Effective Policies and Programs explains how policy compromises are reached and then changed over time as new information becomes available. Derived from the authors’ experiences while serving as a political appointee in the federal government, participating in international committees and boards, and from materials from a graduate course which she teaches on global food and nutrition policy at Tufts University, the 10 case studies presented in this book provide real world learning examples on how contentious issues are resolved in the political process.While each of the ten chapters focuses on a specific topic, the book showcases an overriding theme of food and health justice, equity, and empowerment. Readers will deduce key factors to examine pivotal policy decisions while the author dissects polarizing topics such as examining the successes and failures of dietary guidelines, front label packaging approaches, implications of expanding personalized nutrition, the obesity epidemic and anti-obesity drugs, the role of GMO’s in agricultural production, and more.

  • Elementary Kinetic Modelling in Catalytic Reaction Engineering

    • 1st Edition
    • Joris W. Thybaut + 5 more
    • English
    Elementary Kinetic Modelling in Catalytic Reaction Engineering is a practical focused text that brings together the relevant basics for reaction engineering and shows their applications to a wide variety of examples, whilst looking at the intrinsic kinetics data acquisition, reaction mechanism elucidation, elementary step-based modelling and model-based design and optimization involved.The book aims at spanning the entire process from acquisition of the relevant data in dedicated experimental set-ups, over the proper treatment of the data and the corresponding interpretation up to the quantification of the gained understanding in a model. The latter aspect allows the reader to challenge the interpretation made of the data and design subsequent experiments or improve the interpretation/model formulation. The coverage is not just limited to the generic (theoretical) principles but will also carefully consider and explain their application to a variety of real-life applications including gas- and liquid-phase reactions, heterogeneously catalyzed reactions involving adsorption either in the Henry regime or at full saturation of the catalyst or combined homogeneous-heteroge... reactions.Elementary Kinetic Modelling in Catalytic Reaction Engineering is written primarily for graduate students and postdoc researchers in chemical engineering or applied industrial chemistry studying chemical reaction engineering and catalysis, as well as physical chemists studying kinetics.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 134
    • English
    Advances in Applied Microbiology, Volume 134 presents a comprehensive exploration of the latest innovations in applied microbiology. The book delves into the diverse applications of microbiology across various industries, including agriculture, food production, biotechnology, environmental science, and healthcare. Through a collection of insightful chapters authored by experts in the field, readers are offered in-depth analyses of cutting-edge research, emerging trends, and practical applications of microbiological principles. From novel microbial technologies to the impact of microbiomes on human health and beyond, this book serves as a valuable resource for researchers, professionals, and students seeking to stay informed and inspired by the exciting advancements.

  • Advances in Structural Biology

    Applications in Protein Structure, Function, and Disease
    • 1st Edition
    • Anas Shamsi + 3 more
    • English
    Advances in Structural Biology: Applications in Protein Structure, Function, and Disease offers a comprehensive, practical resource that bridges the latest experimental and computational approaches in structural biology. Backed by real-world case studies, it demonstrates how these technologies can be utilized to serve a range of biological needs. The content spans foundational principles of protein structure and bioinformatics tools, cutting-edge methodologies such as MicroED and Cryo-EM, and the transformative role of artificial intelligence and big data analytics in structural biology. It also considers applications including drug discovery, vaccine development, antiviral therapy, personalized medicine, and the structural basis of aging and neurodegenerative diseases. The book also explores systems integration approaches, combining structural and omics data to advance immunotherapy and cancer treatment, concluding with a look towards future trends in the field.Advances in Structural Biology provides a detailed investigation into the latest developments in structural and computational biology, sharing insights into integrative methodologies that combine both traditional and emerging technologies. This resource is invaluable for advanced students, researchers, and professionals aiming to harness structural biology for innovative solutions in precision medicine and translational research.

  • CDK4/6 inhibitors in Breast Cancer Therapy

    • 1st Edition
    • Pankaj Kumar Singh + 3 more
    • English
    CDK4/6 inhibitors in Breast Cancer Therapy examines the pivotal role of CDK4/6 inhibition in treating hormone receptor-positive (HR+)/HER2-negative advanced breast cancer. The book highlights FDA-approved applications of these inhibitors alongside endocrine therapy and explores ongoing research into their potential as neoadjuvant treatments. It provides insights into the drug discovery and development of CDK4/6 inhibitors, covering their molecular mechanisms, pharmacology, and clinical applications. Chapters address their use in mono and adjuvant therapies, as well as challenges in targeting, while also discussing market potential and post-marketing safety issues.This book is a valuable resource for researchers and academics, enhancing understanding of CDK4/6 inhibitors' chemistry and therapeutic implications. By presenting detailed information on clinical trials and market formulations, it equips the audience with essential knowledge to navigate the complexities of targeted breast cancer therapies and contributes to advancing research in this critical area.

  • Viruses as Therapeutic Agents for Cancer

    • 1st Edition
    • Volume 171
    • English
    Viruses as Therapeutic Agents for Cancer, Volume 171 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Coxsackievirus virotherapy, Oncolytic reovirus, Cancer immunotherapy with oncolytic myxoma virus, Zika Virus as an Oncolytic Therapy, Nonreplicative adenoviral vectors for cancer, VSV Oncolytic Virotherapy, AAV vectors for cancer gene therapy, Adenovirus cancer vaccines, Advancing Clinical Translation of Oncolytic Adenoviruses, and Immunotherapuetic Cancer Terminator Viruses.

  • Nanophytomedicine

    Harnessing Phytochemicals for Advanced Therapeutics
    • 1st Edition
    • Ali Zarrabi + 2 more
    • English
    Nanophytomedicine: Harnessing Phytochemicals for Advanced Therapeutics explores the integration of phytochemicals and nanotechnology to develop advanced therapeutic solutions. The book offers an extensive overview of phytochemicals, explaining their sources, extraction methods, classifications, and applications in medicine. This emerging field aims to utilize the natural properties of phytochemicals to create innovative treatments for various diseases, with a particular focus on hard-to-treat conditions such as cancer. By combining plant-derived compounds with nanomaterials, researchers are unlocking new potential in precision medicine, seeking to enhance the efficacy of treatments while minimizing side effects and improving patient outcomes.In 18 comprehensive chapters, the book delves into the therapeutic properties of phytochemicals, such as their antioxidant, antifungal, and anti-inflammatory effects. It highlights the role of these compounds in combating diseases including cancer, neurological disorders, diabetes, and cardiovascular diseases. The use of nano drug delivery systems is emphasized, showcasing how these technologies can improve the delivery and effectiveness of phytochemicals.

  • Metabolic Memory

    Past, Present and Future Implications
    • 1st Edition
    • Jeena Gupta
    • English
    Metabolic Memory: Past, Present and Future Implications delves into the emerging concept of metabolic memory, exploring how our body's metabolic processes retain a 'memory' of past experiences and how this impacts our current and future health. Drawing on the latest scientific research this book aims to bridge the gap between complex scientific concepts and their practical implications for everyday health and wellness. Metabolic memory has profound implications for understanding chronic diseases, particularly diabetes, cardiovascular diseases, and obesity. Despite its significance, there is a lack of comprehensive resource that make this information accessible to both professionals and the general public. This book fills that gap, providing a detailed yet understandable exploration of how past metabolic states influence present and future health outcomes.

  • Medical and Health Genomics of South Asia

    • 1st Edition
    • Dhavendra Kumar + 1 more
    • English
    Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region.Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

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