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Elsevier

Academic Press

  • Technology-Assisted Physical Gait Rehabilitation

    How Robotics, Data Science, and Neuroscience are Changing Modern Physical Therapy
    • 1st Edition
    • Tomislav Baček + 3 more
    • English
    Technology-Assisted Physical Gait Rehabilitation: How Robotics, Data Science, and Neuroscience are Changing Modern Physical Therapy explores computational modeling techniques, robotic assistance, data science, and other technological tools and how they can be jointly used in driving and guiding physical gait therapy in impairments such as stroke, traumatic brain injury, and incomplete spinal cord injury. This book gathers experts in robotics, human biomechanics, physical therapy, neuroscience, engineering, and medicine, presenting their ongoing work and discusses their views of the future direction of technology-assisted gait therapy, showcasing the latest advancements in the interdisciplinary and multidisciplinary field of technology-assisted gait therapy and strives to outline the developments in the coming years that are needed/likely to make the next big breakthrough in the field.

  • Navigating Tuberculosis

    Insights into Host-Pathogen Protein Interactions
    • 1st Edition
    • Mohammad Shariq + 2 more
    • English
    Navigating Tuberculosis: Insights into Host-Pathogen Protein Interactions, the latest release in the Foundations and Frontiers in Enzymology series, explores the interactions between host proteins and the tuberculosis pathogen, Mycobacterium tuberculosis (M. tb), emphasizing their roles in virulence and pathogenesis. The book delves into mechanistic insights, focusing on their roles in modulating innate and adaptive immunity and understanding TB pathomechanisms by elucidating the interplay between host defenses and M. tb infection. It provides a foundation for developing targeted mitigation strategies and discusses key regulatory pathways and protein factors involved in host-pathogen interactions, informing the design and implementation of innovative approaches to combat TB.This comprehensive volume aims to advance knowledge and strategies to combat tuberculosis, aligning with the World Health Organization's goal of eradicating TB by 2035 by addressing the need for up-to-date information on host-pathogen interactions in tuberculosis and incorporating the latest research findings and advancements. It highlights emerging therapeutic targets among host and TB pathogen proteins and integrates multidisciplinary approaches from microbiology, immunology, and molecular biology, offering a holistic perspective on TB pathophysiology. Researchers will find detailed discussions on key host proteins involved in tuberculosis pathogenesis, the molecular tactics employed by M. tb to subvert host defenses, and host-mediated inhibition strategies targeting M. tb.

  • Harnessing Plant-Stimulating Molecules

    Innovations in Stress Biology and Crop Resilience
    • 1st Edition
    • M. Iqbal R. Khan + 1 more
    • English
    Harnessing Plant-Stimulating Molecules serves as an authoritative reference on the multifaceted molecular regulators and biotechnological innovations underpinning plant resilience to environmental stressors. This volume delivers an exhaustive treatment of diverse classes of signaling entities—including phytohormones, secondary messengers, secondary messengers, reactive oxygen and nitrogen species, and heterotrimeric G proteinss—elucidatin... their roles in complex stress adaptation pathways.In addition to molecular and biochemical foundations, this book explores advanced methodologies such as nanoparticle-facilit... metabolic modulation, RNA interference, and gene-editing strategies aimed at optimizing nutrient utilization. It also highlights the emerging significance of biostimulants in modulating plant–microbe interactions and interplant signaling networks. Detailed discussions on systemic signaling mediated by mobile molecules and photoreceptor-mediat... photomorphogenic responses further enrich the scope.By integrating cutting-edge genetic engineering approaches, particularly CRISPR–Cas systems, with computational modeling for simulating metabolic networks, the volume facilitates accelerated crop improvement strategies essential for addressing contemporary challenges in food security and agroecosystem sustainability.Desig... as an indispensable resource for researchers, advanced graduate students, and industry professionals, Harnessing Plant-Stimulating Molecules bridges fundamental plant molecular biology with translational biotechnology, fostering the development of resilient, high-performance crops adapted to the challenges of a changing climate.

  • Neurobiology of Obsessive-Compulsive Disorder

    • 1st Edition
    • Eric A. Storch + 2 more
    • English
    Neurobiology of Obsessive-Compulsive Disorder provides a comprehensive review of obsessive-compulsive disorder through a neurobiological lens, offering invaluable insights for researchers and clinicians alike. The book begins with a comprehensive introduction to OCD, detailing its definition, historical perspectives, prevalence, and symptomatology, alongside its comorbidities and associated disorders. Delving into the genetic and familial aspects, the book examines genetic predispositions, heritability, and significant genome-wide association studies. In addition, it addresses neuropsychological findings, cognitive dysfunctions, and implications for treatment, alongside neurodevelopmental factors, including early life stress, immune system dysregulation, and environmental risk factors.Special attention is given to PANDAS/PANS as mechanisms of OCD pathogenesis and the insights gained from animal models. Subsequent chapters cover diagnosis, pharmacological treatments, and a range of psychotherapeutic and behavioral interventions, including CBT, ERP, and ACT, as well as neuromodulation techniques. Finally, the book presents neurobiology-informe... treatment approaches, personalized medicine, and integrative strategies, concluding with discussions on current challenges, ethical considerations, and future research directions.

  • The Science of Pharmacology

    • 1st Edition
    • Jahangir Moini + 3 more
    • English
    The Science of Pharmacology offers a detailed and contemporary exploration of medications, delving into the scientific principles behind drug actions and their therapeutic applications. It is an essential resource for students in pharmacology and pharmaceutical sciences, providing foundational knowledge on a wide range of topics. The book addresses the effects of drugs on various bodily systems, such as the nervous, respiratory, and cardiovascular systems, and also covers their impact on mental health and behavior. Beyond the core topics, the book also discusses special subjects like herbal medications and drug interactions.It includes valuable teaching materials, including test banks and quizzes, and offers comprehensive insights into toxicological treatments, making it an invaluable tool for both learning and teaching in the field.

  • Emotional Artificial Intelligence

    Practical Challenges and Applications
    • 1st Edition
    • Rajesh Kumar Dhanaraj + 4 more
    • English
    Emotional Artificial Intelligence: Practical Challenges and Applications explores the intersection of artificial intelligence and human emotions, challenging the myth that AI will replace humans. Instead, it emphasizes how emotional AI can enhance collaboration, improving efficiency across fields like healthcare, transportation, and space exploration. The book explores foundational theories such as Goleman’s emotional model and Ekman’s emotion theory, discussing methodologies for understanding human emotions through natural language processing and the ethical implications of AI in decision-making. It showcases real-world applications, from virtual nurses to emotion-aware driving systems, illustrating how these technologies can improve daily interactions and outcomes.This essential resource equips researchers, practitioners, and policymakers with practical insights for integrating emotional AI into diverse domains. By addressing the complexities of human emotion recognition and ethical frameworks, it provides a forward-looking perspective on enhancing collaboration between humans and AI, ultimately driving improved productivity and efficiency.

  • Contemporary Research Methods in Pharmacy and Health Services - Volume 2

    • 1st Edition
    • Aleda M. H. Chen + 5 more
    • English
    Contemporary Research Methods in Pharmacy and Health Services, Volume Two is an essential resource for researchers and practitioners in the field of pharmaceutical science. Building on the groundbreaking work published in the esteemed journals Research in Social and Administrative Pharmacy (RSAP) and Exploratory Research in Clinical and Social Pharmacy (ERCSP), this volume addresses the critical need for comprehensive and structured methodologies in evaluating and implementing pharmacy services. By transforming selected articles into fully developed chapters, the book enriches the discourse surrounding contemporary research methods, making it an invaluable tool for advancing knowledge and practice.The volume features a diverse array of chapters that cover a wide range of topics, including the use of the Consolidated Framework for Implementation Research (CFIR) to evaluate telepharmacy services for outpatient cancer patients, the translation and validation of adherence measurement tools, and the application of network analysis in health code systems. Other notable contributions explore innovative strategies for improving clinical pharmacy services, conducting scoping reviews in pharmacy education, and employing mixed-methods approaches to enhance medication counseling.

  • Safety Analysis and Risk Control

    From Theory to Implementation
    • 1st Edition
    • Mohammad Yazdi
    • English
    Safety Analysis and Risk Control: From Theory to Implementation provides a comprehensive overview of the fundamental principles of risk analysis, emphasizing their relevance and application in making safety a top priority across industries, offering both depth and breadth in coverage. Following an introduction to core concepts and methodologies, the book considers hazard identification, risk assessment techniques, mitigation strategies, and the implementation of safety measures, supported by real-world, integrated case studies and applications throughout. Each chapter provides practical exercises, tools, and resources to enable readers to apply safety and risk control concepts directly to their work environments.Interac... data sets, hosted on a companion website, encourage active engagement with the material, while an instructor's manual and lecture slides support teaching. As industries face increasingly complex safety challenges and regulatory requirements, this book fulfills an urgent need for clear guidelines and tools to implement effective risk control measures of relevance to students and professionals across the fields of occupational health and safety, environmental science, engineering, business management, and public health, among others.

  • A Comprehensive Guide to Surgical Oncology

    • 1st Edition
    • Aqeel Shakir Mahmood + 2 more
    • English
    A Comprehensive Guide to Surgical Oncology is an authoritative reference that meticulously covers the surgical management of various cancers. Each section delves into the latest surgical techniques, treatment protocols, and post-operative care strategies, supported by up-to-date research and clinical evidence. Enriched with detailed illustrations, case studies, and expert insights, this book is an indispensable resource for professionals and students alike. The primary purpose of this book is to provide a comprehensive, up-to-date resource that addresses the current challenges and advancements in surgical oncology. As cancer treatment evolves rapidly with continuous improvements in surgical techniques and multidisciplinary care, there is a pressing need for a new resource that synthesizes these developments into a coherent guide. This book aims to fill that gap by offering a thorough overview of the latest surgical oncology practices, thereby enhancing the knowledge and skills of its readers. This book solves several key problems for its readers by bridging the gap between rapidly advancing research and clinical practice, ensuring access to the latest information. It consolidates a vast amount of information into one comprehensive volume, saving readers the time and effort of consulting multiple sources. Providing practical guidance on the surgical management of a wide range of cancers, it helps practitioners make informed decisions in clinical settings. For students and trainees, it serves as a valuable educational tool that covers both foundational knowledge and advanced concepts in surgical oncology, offering multidisciplinary insights that foster a better understanding of the collaborative efforts required in cancer treatment.

  • Unlocking Sirtuins

    Cellular Biology to Translational Research
    • 1st Edition
    • Pranav Kumar Prabhakar + 1 more
    • English
    Unlocking Sirtuins: Cellular Biology to Translational Research explores the intricate roles of sirtuins, from basic principles to clinical significance. The book is organized into six parts, covering foundational concepts, roles in aging and metabolism, disease pathology, therapeutic strategies, future research directions and potential challenges. Topics include the structure and evolution of sirtuins, their mechanisms of action, and their impact on neurodegenerative diseases, cardiovascular health, and cancer. It also features detailed chapters on sirtuin modulators, drug discovery, the latest technologies and tools in the field, emerging trends, and the challenges, ethical considerations and future directions of sirtuin-targeted therapies. The content is complemented by case studies, clinical insights, and step-by-step procedures, offering a comprehensive and practical exploration of the subject. “Unlocking Sirtuins” offers an in-depth overview of sirtuin biology, bridging fundamental science with clinical application. It serves as an essential resource for researchers, clinicians, and advanced students working across cellular and molecular biology, biochemistry, pharmacology, aging, metabolic disorders, translational medicine and related fields.

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