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Academic Press

  • Primary Aldosteronism: Physiopathology and Diagnosis

    • 1st Edition
    • Volume 130
    • English
    Primary Aldosteronism: Physiopathology and Diagnosis, Volume 130 focuses on the physiopathology and diagnosis of primary aldosteronism, covering some important topics such as Aldosterone: synthesis and regulation, Pathophysiology of primary aldosteronism, Prevalence of primary aldosteronism and screening indications, Clinical manifestations of primary aldosteronism and cardiometabolic risk, Diagnosis of primary aldosteronism: renin activity, renin concentration and aldosterone/renin ratio, Diagnosis of primary aldosteronism confirmatory test, Diagnosis of Primary Aldosteronism: Novel Workup Strategies and Biochemical Tools, and much more. Additional sections cover Genetics in primary aldosteronism, Low-renin hypertension, Adrenal venous sampling interpretation and other diagnostic lateralization tools in PA, and Aldosterona & Cortisol cosecretion.
  • Genetics of Bone Biology and Skeletal Disease

    • 3rd Edition
    • Rajesh V. Thakker + 3 more
    • English
    Genetics of Bone Biology and Skeletal Disease, Third Edition is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid, and related disorders, and vitamin D and renal disorders.Sections cover bone biology and structure, joint and cartilage biology, principles of endocrine regulation, the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasia, rarer bone disorders, and much more.
  • International Review of Neurobiology

    • 1st Edition
    • Volume 186
    • English
    International Review of Neurobiology, Volume 186 presents the latest developments in the field, with chapters written by an international board of authors. This volume offers a broad overview of current research and perspectives in neurobiology, serving as a valuable reference for researchers, clinicians, and students interested in understanding advances across diverse areas of the discipline.
  • Emerging Omics Technologies for Sustainable Agriculture

    • 1st Edition
    • Geerten W. Vuister + 3 more
    • English
    Emerging Omics Technologies for Sustainable Agriculture provides a comprehensive overview of the transformative potential of advanced tools such as AI, genomics and proteomics to ensure future agricultural production.The integration of genomics, transcriptomics, proteomics, and metabolomics has advanced the understanding of plant and microbial systems and the application of this knowledge has enabled precision farming, optimizing crop yield and minimizing environmental impact. There are unprecedented opportunities to enhance crop yields, improve pest and disease management, to optimize resource utilization and to mitigate environmental impacts. Through the use of advanced data analytics, machine learning, and predictive modeling, researchers can decipher complex biological processes and develop innovative solutions for agricultural challenges.Emerging Omics Technologies for Sustainable Agriculture explores the advancements in AI-driven omics technologies, such as genome editing, transcriptomics, and phenomics, and their applications in crop improvement, soil health monitoring, and precision agriculture.
  • Evolution of Nervous Systems

    • 3rd Edition
    • Jon H. Kaas + 1 more
    • English
    Evolution of Nervous Systems, Third edition Four-volume set includes wholly new content, all chapters from the previous edition have been thoroughly updated, and 50 brand new contributions by leading experts have been added. Each of the volumes has been carefully restructured to offer expanded coverage of non-mammalian taxa, mammals, primates and the human nervous system. The basic principles of brain evolution are discussed, as well as mechanisms of change, which involve gene expression and altered courses of embryonic development. The reader can select from chapters on highly specific topics as well as those providing an overview of current thinking and approaches. This timely new edition of Evolution of Nervous Systems is a unique major reference work, offering the gold standard for those interested in evolution and in nervous systems.
  • New Transportation Modes and ‘Old’ Transportation Modes that are in the Process of Renewing Themselves

    • 1st Edition
    • Volume 17
    • English
    New Transportation Modes and ‘Old’ Transportation Modes that are in the Process of Renewing Themselves, Volume 17 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this new release include The environmental impact of high-speed rail, Past, Present and Future States of Research on Autonomous Electric Vehicles, Urban Air mobility, Micromobility, Mobility as a Service, Aviation, Sustainable city logistics, Autonomous vehicles, Light Rail, Bus Rapid Transit, and more.
  • How to Develop Robust Scale-up Strategies for Complex Injectable Dosage Forms

    From Bench to the Clinics
    • 1st Edition
    • Neelam Poonia + 2 more
    • English
    How to Develop Robust Scale-up Strategies for Complex Injectable Dosage Forms: From Bench to the Clinics provides a comprehensive roadmap for transitioning complex injectable formulations from the laboratory to clinical applications. Offering an exploration of various complex injectables, including liposomal dosage forms, nanoparticles, and microspheres, this book delves into dosage form design, excipient selection, stability studies, and optimization techniques. The book examines manufacturing technologies such as aseptic processing, sterile filtration, and lyophilization, and their applications in producing complex injectables. Discussions on quality control measures, analytical techniques, and quality assurance practices are provided to ensure consistent quality and purity throughout the manufacturing process.Readers will benefit from the expert knowledge and practical insights shared by industry professionals and leading researchers, including successful examples of marketed complex injectables. Highlighting best practices and regulatory requirements, this book offers a comprehensive overview of the guidelines for the development, manufacturing, and commercialization of complex injectables. Ideal for pharmaceutical scientists, formulation developers, and regulatory professionals, this book is a valuable resource for anyone involved in the scale-up and commercialization of complex injectable dosage forms.
  • Marine Microbial Products

    Applications and Opportunities
    • 1st Edition
    • Sesan Abiodun Aransiola + 2 more
    • English
    Marine Microbial Products: Applications and Opportunities delves into the extensive world of marine microbes, an assemblage of organisms that contain a broad array of bioactive chemicals. Written and edited by a diverse team of environmental microbiologists, this book provides readers with a foundational understanding of marine microbial taxa, the products that may be synthesized from these organisms, technological innovations, and future directions of research. Chapters collate the most current research in healthcare, sustainability, and commercial production, presenting readers with the latest information on antibiotics, antivirals, anticancer therapeutics, immunosuppressive chemicals, bioremediation, food processing, biofertilizers, biopesticides, cosmetics, pigments, probiotics, and functional foods.The book is structured for accessibility to academic and professional audiences, spanning a variety of sectors. It is an indispensable resource for students, professors, researchers, and industry professionals in biology, biotechnology, sustainable development, food, healthcare sciences, and adjacent industries.
  • Natural Product Drug Discovery

    Highly Anticipated Natural Molecules
    • 1st Edition
    • Ning Li + 1 more
    • English
    Natural Product Drug Discovery: Highly Anticipated Natural Molecules, a new volume in the Drug Discovery Opinion series, provides a comprehensive examination of the role of natural products in innovative drug development. The book addresses the significant challenges that highly active natural molecules face in the drug development process, including issues related to bioavailability and potency. Sections present analyses of various classes of natural products, including polysaccharides, volatile oils, and diterpenoids, exploring their chemical properties, biological activities, and potential clinical applications. Each chapter, written by leading experts, offers insights into structural modification techniques, naturally sourced inhibitors, and the application of green biomanufacturing strategies.It will serve as an essential resource for researchers, pharmacologists, and industry professionals involved in natural product drug discovery. Readers will find the necessary information to navigate the complexities of the field, emphasizing the integration of traditional knowledge with modern scientific approaches. Through a thorough understanding of these natural compounds, this book aims to contribute to the advancement of therapeutic innovations in pharmacotherapy.
  • Multidimensional Signal Processing

    • 1st Edition
    • Volume 54
    • English
    Multidimensional Signal Processing, Volume 54 in the Handbook of Statistics series is dedicated to presenting the latest developments and methodologies in multidimensional signal processing. The book aims to provide a comprehensive overview of the theories, models, and methods that form the foundation of this field. Chapters in this new release include Robust Parameter Estimation of Two Dimensional Chirp Model, Computability Theory for Multidimensional Signal Processing, Tensor signal processing, Spectral compressed sensing by structured matrix optimization methods, Space-time imaging, Hypercomplex Widely Linear Processing, and much more. The book's chapters are meticulously curated to offer detailed, educational content rather than conventional journal-style articles.Other chapters cover Hypercomplex phase retrieval, Hypercomplex widely linear estimation, MIMO radar signal processing, Computational lidar, Signal processing applications of higher-dimensional graphs, Space-Time Radio Signal Processing by Photonic Upconversion, Computational imaging, and Topology identification and learning over graphs using multi-dimensional data.