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Academic Press

  • Microglial Aging

    Basic, Translational and Clinical Advances
    • 1st Edition
    • Marie-Eve Tremblay
    • English
    Microglial Aging: Basic, Translational, and Clinical Advances explores groundbreaking research on microglial function in the context of aging. This comprehensive resource delves into the physiological roles of microglia, the effects of aging on their structure and activity, and their significance in age-related neurodegenerative diseases. With insights from basic, translational, and clinical studies, it provides a thorough understanding of microglial health and its impact on aging. The book discusses how lifestyle choices can enhance microglial functions and prevent neurodegenerative diseases. It covers both pharmacological and non-pharmacological approaches, such as the ketogenic diet, cannabinoids, psychedelics, and non-invasive vagal nerve stimulation.This text is invaluable for researchers and clinicians focused on improving the quality of life for an aging population.

  • A Quick Reference to Obstetric Anesthesia

    • 1st Edition
    • Adithya Devadas Bhat + 1 more
    • English
    A Quick Reference to Obstetric Anesthesia is a comprehensive resource on the latest in anesthetic care for the pregnant patients. It covers the newest evidence on various critical topics in obstetric anesthesia, and the inclusion of recommended perioperative protocols provides definitive references for optimal care. This book serves as an “in the moment” tool for solving challenging clinical problems, while functioning as a reference for both experienced clinicians and trainees. It also includes relevant patient management protocols, as well as numerous emerging topics that are lacking in presently available texts.A Quick Reference to Obstetric Anesthesia is meant for anyone seeking immediately accessible information to facilitate real-time care of pregnant patients. Its approachable yet comprehensive knowledge base will be appreciated by anesthesia professionals at every level.

  • Decoding Plant–Environment–Microbiome Interactions in Stress-Resilient Agriculture

    • 1st Edition
    • Asfa Rizvi + 4 more
    • English
    Decoding Plant–Environment–Mi... Interactions in Stress-Resilient Agriculture delivers both foundational understanding and forward-looking perspectives on the rapidly advancing field of phytomicrobiome research. Showcasing the unique advantages of microbial partnerships in stressed soils, the book explores how optimizing plant–microbiome interactions can transform crop productivity and sustainability.Focus... on the phytomicrobiome’s diverse components—including root-associated microbiota, plant growth-promoting rhizobacteria, endophytes, phosphate-solubilizi... microorganisms, arbuscular mycorrhizal fungi, and actinomycetes—the volume reveals how these microbial networks enhance plant stress tolerance, rehabilitate degraded or contaminated soils, and sustain yields under adverse conditions.Harnessin... these natural bioresources effectively requires an integrated understanding of the complex crosstalk between plants and their associated microbes, from molecular signaling to ecological mechanisms. Drawing on insights from internationally recognized scientists and leading academicians, this book consolidates cutting-edge research and emerging innovations, providing readers with the knowledge needed to advance stress-resilient and environmentally sustainable agriculture.

  • Neuro-ophthalmological Pain

    Diagnosis and Treatment
    • 1st Edition
    • R. Silva-Néto + 1 more
    • English
    Neuro-ophthalmologic... Pain: Diagnosis and Treatment is written to address the many problems faced by patients with ocular pain of neurological origin. These patients are often incorrectly referred to ophthalmologists and otolaryngologists to diagnose eye problems or sinus disease, respectively. While these ailments are neurological in nature, the average time between the onset of pain and a visit to a neurologist is 13 years. By this point, most patients have received at least one wrong diagnosis. Additionally, some patients have undergone several unnecessary investigative tests, received improper, flawed treatments, and continued to suffer. "Neuro-ophthalmologi... Pain: Research and Treatment" contains information on a multitude of often-overlooked ailments in a single, comprehensive volume, for use by the neurologist as well as general practitioners looking to guide their patients toward appropriate care. It will provide potentially life-changing information for those with ocular pain with decreased vision; ocular pain with ophthalmoplegia or ophthalmoparesis; ocular pain with papilledema; and ocular pain with autonomic manifestations Neuro-ophthalmologic... Pain: Research and Treatment is a powerful tool in helping physicians establish correct diagnoses, so that they may either provide proper treatment, or refer their patients to the correct medical specialists.

  • Machines of the Farm

    Theory and Practice
    • 1st Edition
    • Divaker Durairaj Chelladurai
    • English
    Machines of the Farm: Theory and Practice is a comprehensive textbook designed to provide a thorough understanding of farm machinery, its mechanics, and management. It dives deeply into practical concepts related to agricultural equipment, including calibration and adjustments essential for agricultural engineers. By blending theoretical insights and practical applications, the book covers topics such as mechanics, materials, selection, and performance evaluation. Each chapter includes worked examples and exercises to ensure a broad and practical understanding of the subject.The book not only details specific machines and scientific principles but also includes chapters on primary and secondary tillage equipment, machinery for sowing, weed control, crop protection, manure application, and harvesting. It reviews the testing of farm machines, earth-moving equipment, and considers performance against cost. This textbook is a valuable resource for upper-level undergraduate and graduate students in Agricultural Engineering, as well as professionals in the field, farm machinery designers, and agricultural consultants. Additionally, it offers a full solutions manual for instructors and worked examples for students to further their learning objectives.

  • Performance Evaluation and Attribution Volume One

    Asset Pricing and Models
    • 2nd Edition
    • Russ Wermers + 2 more
    • English
    Performance Evaluation and Attribution Volume One: Asset Pricing and Models, Second Edition, presents an updated, comprehensive exploration of portfolio evaluation. Based on the authors’ Performance Evaluation and Attribution of Security Portfolios (2012), this Second Edition adds four new chapters and updated content throughout in its practical approach to measuring manager skills and using recent statistical techniques to solve investment problems. Added are new factor models, including the newly developed q-factor model and the new models of Fama and French, new examples, and new work on qualitative considerations. This highly detailed new edition combines academic rigor with practical applications and guidance for applications of diverse approaches.

  • Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

    • 3rd Edition
    • Herbert B. Newton
    • English
    Handbook of Brain Tumor Chemotherapy, Molecular Therapies, and Immunotherapy, Third Edition offers a unique cutting-edge collection of basic science and clinical information brain tumor chemotherapy research. The book represents the most complete single-volume resource available for information on the subject of brain tumor chemotherapy. Including a multidisciplinary approach, this volume combines recent advances tumor therapy with molecular biology, molecular therapeutics, immunobiology, and immunotherapy approaches in one location. Chapters new to this volume include cutting-edge research on the molecular underpinnings of brain tumors such as glioblastoma, other gliomas, and targeted molecular therapies to consider for treatment.

  • Translational Cardiothoracic Surgery

    • 1st Edition
    • Adam E.M. Eltorai
    • English
    Translational research is essential to the advancement of medicine. This Cardiothoracic-speci... instructional guide to translational medical research serves as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in cardiothoracic surgery, this volume provides a clear process for understanding, designing, executing, and analyzing clinical and translational research within the field.

  • Episodes in the History of Medical Science

    Discovery Meets Orthodoxy
    • 1st Edition
    • Anthony R. Rees
    • English
    Episodes in the History of Medical Science: Discovery Confronts Orthodoxy highlights key moments in history where scientific and medical advances faced acceptance and rejection by the prevailing orthodoxy. This book places present-day disease protection in context by exploring significant medical and scientific theories, their success stories, challenges, and the frequent resistance to new ideas. It shows how acceptance of scientific discoveries often lags due to conservatism within the scientific community and broader socio-political and cultural influences. The book examines the origins of medical theory and practice, from the revolutionary ideas of Hippocrates and Galen to the rise of Islamic Medicine and the scholasticism of the Middle Ages. It covers the arrival of syphilis in Europe and the ensuing medical debates, the historical battle against smallpox through variolation and vaccination, and the skepticism faced by groundbreaking discoveries in the 19th and 20th centuries. Key topics include the gene debate, the thalidomide tragedy, the antibody revolution, and the paradigm shift in understanding stomach ulcers. The narrative also addresses the modern era's anti-vaccinationism and vaccine hesitancy, emphasizing the ongoing tension between scientific integrity and public acceptance. Episodes in the History of Medical Science: Discovery Confronts Orthodoxy is a valuable resource for medical professionals, researchers, historians, and students. It underscores the importance of scientific and medical integrity, the pursuit of truth, and validated scientific communication. By providing historical insights and examples of perseverance in the face of skepticism, this book offers valuable lessons for improving public health and understanding the dynamic journey of medical science.

  • An Introduction to the Finite Element Method with the Variational Approach

    • 1st Edition
    • Prakash Mahadeo Dixit + 1 more
    • English
    An Introduction to the Finite Element Method with the Variational Approach offers a comprehensive solution to the gaps often found in introductory texts on the Finite Element Method (FEM). The book provides a thorough introduction to the fundamental principles of linear and time-independent FEM within the variational framework. It meticulously covers the derivation of 1-D FEM equations based on variational functionals, encompassing both linear and higher-order elements, and shape functions driven by convergence criteria. Furthermore, it explores 1-D numerical integration, outlines coding procedures, and provides insights into handling material nonlinearity and time-dependent scenarios.Expanding into 2-D problems, the book offers derivations of 2-D FEM equations tailored to diverse engineering disciplines, including Steady-State Heat Conduction, Solid Mechanics (covering torsion, plane strain/axisymmetric cases, and the bending, stability, and vibrations of thin plates), as well as Fluid Mechanics (addressing incompressible inviscid and viscous fluids). It includes detailed discussions on element continuity, numerical integration techniques, and even includes 2-D codes for selected problems. The book concludes by delving into recent advancements in FEM, with a specific focus on applications in machine learning and isogeometric analysis.

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