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Elsevier

Academic Press

  • Protein Dynamics

    Experimental and Computational Approaches
    • 1st Edition
    • Ana-Nicoleta Bondar + 1 more
    • English
    Protein Dynamics: Experimental and Computational Approaches investigates protein biology from a biophysical standpoint. The book covers a wide range of topics, including functional protein dynamics, intrinsically disordered proteins, protein folding, misfolding and aggregation, and membrane protein-protein communication. Protein allosteric conformational changes caused by drug binding and disease-associated mutations are also featured, alongside protein dynamics in the context of computer-based drug design. Biophysical techniques for investigating protein structure-dynamics-f... relationships across these topics are explored, considering the latest experimental and computational approaches in the field. This book is an ideal reference for researchers in working in biophysics, biochemistry, and related areas.

  • Methods in Chemical Process Safety

    • 1st Edition
    • Volume 10
    • English
    Method of Process Systems in Energy Systems Volume Ten, the latest release in the Methods in Chemical Process Safety series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Cybersecurity of Energy Systems, Risk-based alarm design and management, Data Fusion and Machine Learning in Fault Detection & Diagnosis, Resilience of Emerging Energy System, Identifying Cyber Risks in Energy Systems: Challenges and Strategies, Numerical risk-based models for optimizing renewable energy systems, and more.Other sections cover Advancing Operational Risk Assessment in emerging Energy Systems: Methods and Applications, From Process Design to Control: Advancing Instrumented Energy System for Sustainable and Efficient Operations, Approaches for sustainability assessment in the design of energy systems, Reliability-Informed Economic Assessment of Blue Hydrogen Production Design in a Low-Carbon Energy System, Cyber-Secure and Safe Operation of Renewable Energy Distribution Systems, and more.

  • Motor Control Methods and Clinical Applications

    • 1st Edition
    • Robert Chen + 1 more
    • English
    Motor Control Methods and Clinical Applications provides a detailed review on the use of non-invasive brain stimulation to study motor control. Split into two distinct parts, this new volume covers the latest research in motor control, including real examples of these methods in a clinical setting. The first part covers advanced methods such as transcranial magnetic, electrical and ultrasound stimulation, long latency, spinal reflexes, multichannel EMG, and EEG-EMG analyses that can be used to examine and modulate the motor system. The second part of the book addresses the clinical applications of these methods.

  • Real-World Research to Improve Dementia Care

    Embedding Pragmatic Trials of Non-Drug Interventions
    • 1st Edition
    • Jill Harrison + 1 more
    • English
    Real-World Research to Improve Dementia Care: Embedding Pragmatic Trials of Non-Drug Interventions addresses the urgent need for effective care strategies for the over 50 million individuals living with Alzheimer's disease and related dementias. This insightful book introduces embedded, pragmatic trials as a way to bridge the gap between clinical research and everyday practice, emphasizing collaboration among healthcare systems, researchers, and communities. Through a series of chapters, the book explores partnership strategies, ethical considerations, and the selection of meaningful outcome measures, all aimed at enhancing dementia care. The authors present case studies that showcase successful interventions and innovative practices across care settings.By highlighting both the challenges and solutions in dementia care, this book serves as a vital resource for healthcare professionals and researchers. It advocates for a compassionate approach that values the voices of individuals living with dementia, ultimately aiming to improve their quality of life.

  • 3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology

    Innovations for Personalized Oncology
    • 1st Edition
    • Ashok Kumar + 2 more
    • English
    3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology: Innovations for Personalized Oncology presents a comprehensive exploration of the transformative role of 3-D bioprinting and bio-generative engineering in modern medicine, with a specific focus on precision oncology. By examining innovative applications of these technologies, the book aims to bridge the gap between emerging scientific advancements and their practical implications in clinical settings. It delves into how patient-specific models of human tissues and organs can revolutionize drug testing, disease diagnostics, and personalized treatment plans, ultimately enhancing the quality of cancer care.Addressing critical challenges in oncology, this book highlights how 3-D bioprinting and bio-generative engineering can improve the accuracy of drug efficacy evaluations, reduce reliance on animal testing, and tackle the pressing issue of organ shortages for transplantation. Furthermore, it emphasizes the ethical considerations and regulatory challenges associated with integrating these technologies into everyday oncology practice, ensuring a balanced perspective on their adoption.

  • The Dual Role of Inflammation in Cancer

    • 1st Edition
    • Surajit Pathak + 1 more
    • English
    The Dual Role of Inflammation in Cancer Genesis and Therapy explores the pivotal role inflammation plays in the development and progression of cancer. The book delves into how chronic inflammation creates a microenvironment that supports tumor growth by promoting cellular proliferation, survival, and migration while suppressing immune responses. It traces historical observations, linking inflammation to cancer while also examining how inflammatory cells and mediators contribute to various stages of tumorigenesis. In addition, it discusses the implications of inflammation on cancer treatment, highlighting the potential of anti-inflammatory agents and immunotherapy in targeting the inflammatory tumor microenvironment.By elucidating on the intricate relationship between inflammation and cancer, the book aims to pave the way for more effective and personalized cancer treatment strategies. As such, it is a valuable resource for researchers in immunology and oncology.

  • The Alkaloids

    • 1st Edition
    • Volume 96
    • English
    The Alkaloids, Volume 96 continues the longstanding tradition of this authoritative series, presenting in-depth and up-to-date reviews on the chemistry and biology of alkaloids. This volume features comprehensive chapters on the chemistry of quinoline alkaloids, the chemistry and biology of securinega alkaloids, and the structure, biological activity, and chemical synthesis of Myrioneuron alkaloids. Together, these contributions provide critical insights into alkaloid structures, biosynthetic origins, biological activities, and synthetic strategies. This volume serves as an essential reference for researchers and advanced students working in natural products chemistry, medicinal chemistry, chemical biology, and pharmacognosy.

  • Histone Deacetylases in Neurodegenerative Disease Part A

    • 1st Edition
    • Volume 733
    • English
    Histone Deacetylases in Neurodegenerative Disease, Part A, Volume 733 in the Methods in Enzymology series, highlights new advances, with this volume presenting chapters on topics such as HDAC Inhibitor-Induced Endoplasmic Reticulum (ER) Stress, Specific activation of p300/CBP Lysine acetyltransferases induces adult neurogenesis and synaptic plasticity, Chromatin immunoprecipitation assay for analyzing histone H3-mediated regulation of copper homeostasis, Histone Deacetylase 6 modulates Tau structure and function, Histone Acetylation in Parkinson Disease, DNA methylation and histone modification in hypoxic conditions, The extracellular Histone Deacetylase 6 modulates the actin networks in neuronal cells, Epigenetic modulators as therapeutics for neurodegenerative disorder/Alzheimer's disease, and much more.Additional chapters explore Sirtunins in mitochondrial physiology and energy homeostasis, Sirtunins in metabolic homeostasis, Conformational flexibility of histone variant CENP-ACse4 is regulated by histone H4: A mechanism to stabilize soluble Cse4, Analysis of copper toxicity by western blotting of secretory proteins translocated via Sec61 channel, Histone deacetylase as a potential therapeutic target for memory disorders, Histone deacetylases in Neurodegeneration, Role of Deubiquitinases in Regulating Tau Acetylation and Autophagic Clearance in Alzheimer’s Disease, Histone deacetylases in Neurodegeneration and neuronal plasticity, and more.

  • Mastering Supraventricular Tachycardia Diagnostics in the Electrophysiology Lab

    • 1st Edition
    • Konstantinos P. Letsas + 1 more
    • English
    Mastering Supraventricular Tachycardia Diagnostics in the Electrophysiology Lab is dedicated to the diagnostics of supraventricular tachycardias (SVTs) for the electrophysiologist. The book is organized as a flowchart, allowing readers to accurately determine the proper next steps to take when managing patients' presenting symptoms. Its diagnostic approach starts with the evaluation of the 12-lead ECG, continues with electrophysiological observations and maneuvers, and ends with three-dimensional mapping techniques and real-life cases. Chapters are concise and focus on demonstrating the background of each maneuver in a simple manner by using sketches and electrograms from the lab.Each chapter contains a brief summary of when to use a maneuver, how to perform it, what to expect as responses to the maneuver, and interpretation of possible responses. Final chapters discuss real-life cases where the aforementioned diagnostic approaches are adapted to conditions that may not be ideal (for example, non sustained tachycardias). The book provides a start to finish explication of how to comprehend, diagnose, and manage all aspects of SVT.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 121
    • English
    Advances in Food and Nutrition Research, Volume 121 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Precision nutrition in autoimmune diseases, Current and novel food allergens: cross-reactivity and cross-sensitization risks, Microbiota, fermentation, and metabolite biotransformation: pathways to functional foods and personalized nutrition, Pectins and Modified Pectins: Bridging Food Technology and Human Health Innovations, Methodological Approaches to Assess Protein Digestibility with an Emphasis on Plant-Derived Foods, Recent advances in natural melanin added food packaging, and much more.Additional sections cover A comprehensive overview of the formation of biogenic amines in seafood, Microplastics as an unexplored emerging food contaminant: a challenge for food safety, and Animal-origin food waste hydrolysates for its use as a food/feed ingredient.

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