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Elsevier

Academic Press

  • An Authoritative Guide to Chronic Pediatric Abdominal Pain

    Pathophysiology, Diagnosis and Management
    • 1st Edition
    • Miguel Saps + 1 more
    • English
    An Authoritative Guide to Chronic Pediatric Abdominal Pain: Pathophysiology, Diagnosis and Management provides a comprehensive and extensive overview of all aspects relevant to the care of children with abdominal pain. It includes chapters tailored to each discipline, level of training, and primary interest (clinical or research), covering daily practice, diagnosis, testing, conventional and complementary treatments, interdisciplinary care, and the transition to adult gastroenterology treatment. The book critically updates the evidence behind these methods and prepares readers to understand more advanced techniques. Topics include early adverse life events, intestinal permeability, visceral hypersensitivity, sex differences, microbiome infections, use of antibiotics, and the microbiome.Informati... on clinical perspectives and management in the emergency department helps inform pediatricians, gastroenterologists, residents, fellows, and nurse practitioners about the scientific basis for prior workups, differential diagnoses, and the rationale behind them. In addition, this book helps clinicians understand the basic research behind these factors, how they influence pathophysiology, clinical presentation, progression, and outcomes.

  • Green Intrusion Detection Systems for IoT

    • 1st Edition
    • Saeid Jamshidi + 3 more
    • English
    Green Intrusion Detection Systems for IoT tackles the pressing security challenges posed by the rapid expansion of the Internet of Things (IoT). The book delves into innovative, lightweight security models and energy-aware IDS mechanisms that strike a balance between security efficacy, computational efficiency, and environmental sustainability. Sections discuss the transformative role of IoT and the need for sustainable security solutions, highlight the distinctions between traditional and Green IDS, focus on lightweight security models essential for resource-constrained IoT devices, and delve into energy-efficient network designs.Additional sections explore green IDS mechanisms, including machine learning and distributed approaches, IoT vulnerabilities and mitigation strategies, practical examples of sustainable IDS in various smart environments, real-world case studies, and future directions in sustainable IoT security. The book concludes with actionable recommendations that align technological advancements with global sustainability goals.

  • Protein Kinase Inhibitors

    The Promise of Natural Products in Cancer Therapeutics
    • 1st Edition
    • Md. Imtaiyaz Hassan + 1 more
    • English
    Protein Kinase Inhibitors: The Promise of Natural Products in Cancer Therapeutics explores a novel therapeutic avenue for cancer treatment through nutraceutical-based kinase inhibitors. The book covers their historical background, outlook, mechanistic pathways, and clinical aspects, highlighting their relevance in cancer therapy. It also examines the potential of polyphenolic derivatives and other natural compounds in inhibiting key kinases involved in major cancer signaling pathways, focusing on their application in clinical trials and marketed drugs. Sections explore the implications of polyphenols in cancer management, novel sources of breast cancer inhibitors, the role of natural products in lymphoma therapy, and the multitarget potential of phytochemicals. Each chapter is designed to provide a thorough understanding of how natural products can be harnessed to develop innovative cancer therapeutics. It will serve as a valuable resource for academics, scientists, young researchers, students, and pharmacists working or interested in kinase biology and cancer therapeutics with its unique perspective on using nature's own arsenal to combat cancer.

  • The Fauna of Australia’s Tropical Savanna Biome

    Biodiversity, Biogeography, and Conservation
    • 1st Edition
    • Alan Andersen + 1 more
    • English
    The Fauna of Australia's Tropical Savanna Biome: Biodiversity, Biogeography and Conservation considers the full range of vegetation types and freshwater systems that occur within the dominant savanna matrix in Australia's monsoonal tropics. Edited by renowned experts of tropical ecology, it provides descriptions of diversity, taxonomic, functional composition and endemism, and ecological and biogeographical questions of wide interest. Chapters explore how diversity and composition vary among different habitats in a savanna landscape and along the savanna rainfall gradient. The book also considers how distinctive savanna fauna is within Australia and compared with tropical savannas elsewhere in the world. The book considers the unique biogeographic and evolutionary history of this highly diverse and distinctive biome, building on a rich foundation of knowledge accrued over decades of research on many aspects of the region's biodiversity, conservation values, and challenges. This is an indispensable resource for students and researchers studying tropical biodiversity, as well as conservationists and land managers of Australia's tropical savanna biome and those found across the globe.

  • Disorders of Memory

    • 1st Edition
    • Andrew E. Budson + 1 more
    • English
    Disorders of Memory provides a new update on research pertaining to memory disorders, with a central focus on differing components of memory processes, as well as clinical conditions affecting memory. The book covers methods of assessment and clinical treatment, management, and rehabilitation of these disorders. With chapters written by leading international experts, it provides an overview of our current knowledge on memory disorders that will be of benefit to both researchers and practitioners interested in neurology.

  • Alternatives to Antibiotics for Sustainable Aquaculture

    • 1st Edition
    • Baskaralingam Vaseeharan + 2 more
    • English
    Alternatives to Antibiotics in Sustainable Aquaculture explores issues associated with antimicrobial use and available alternatives to support aquatic animal health. The book unveils the issues related to antimicrobial use and offers alternative approaches to foster a more sustainable global aquaculture industry. These approaches encompass natural-based antibiotic substitutes, antimicrobial peptides, probiotics, prebiotics, and postbiotics, as well as immunostimulants and feed additives. Additionally, chemical alternatives, vaccines, bacteriophages, quorum quenching, and antibiofilm approaches are explored. The future of aquatic animal health is covered through the lens of novel technologies, including genomic and metabolomic approaches, nanotechnology, and nanobubble methods.This book provides insightful knowledge for individuals from both academic and private sectors, as well as policymakers and regulators. The knowledge gathered in this book is intended to positively guide aquaculture supply chains toward a sustainable transformation of the industry.

  • Investigative and Predictive Forensic Microbiology

    • 1st Edition
    • Hirak Ranjan Dash
    • English
    Investigative and Predictive Forensic Microbiology showcases the latest advancements in microbial technology for forensic applications, covering a wide range of topics in forensic microbiology. Sections explore human normal microflora, cover classical methods of analyzing microbes, discuss microbial tools in forensic medicine that address post-mortem analysis, and delve into microbial biomarkers for estimating time of death. Investigative microbiology topics include analyzing body fluids, geolocation prediction using microbes, ancient microbial DNA analysis, biodefense, and emerging infections.The book's final section focuses on challenges and future approaches, covering statistical interpretation of data, regulatory considerations, and ethical implications of forensic microbiology. With contributions from renowned experts in the field, this book is a comprehensive resource for researchers and practitioners in microbiology, genetics, forensic science, and for law enforcement professionals and advanced students.

  • Genome Damage

    Repair and Adaptation Across Life
    • 1st Edition
    • Vinod K. Kannaujiya + 2 more
    • English
    Genome Damage: Repair and Adaptation Across Life explores the significance of nucleic acid damage from environmental pollutants, UV radiation, and other stressors that can lead to mutations, genetic instability, and various diseases, including cancer. This book delves into the mechanisms of DNA and RNA repair, which are crucial for maintaining cellular health and enabling evolutionary adaptations. It examines these intricate processes across microbes, plants, and animals, providing a comprehensive understanding of how genetic materials are regulated and repaired under diverse environmental conditions.Other sections cover a wide range of topics, including advanced molecular mechanisms of nucleotide repair, UV-induced damage, apoptosis cell death and autophagy, genetic instability in crops, and the role of post-translational modifications in DNA repair, the detection and quantification of DNA damage, the impact of synthetic chemicals and climate change on nucleic acids, and the therapeutic significance of DNA repair mechanisms. The book closes with a look towards future perspectives.

  • Advances in Hepatorenal Syndrome Research

    Untangling Pathophysiology, Improving Diagnostic Strategies, and Leveraging Therapeutic Innovations
    • 1st Edition
    • Justin Belcher
    • English
    Advances in Hepatorenal Syndrome Research: Untangling Pathophysiology, Improving Diagnostic Strategies, and Therapeutic Innovations is a comprehensive review of the historical perspectives, prevalence, and prognosis of HRS, offering insights into its evolving clinical recognition and shifting paradigms of pathophysiology. Explore the multifaceted pathophysiology of HRS as experts navigate the complexities of cardiac dysfunction, inflammatory cytokines, and other modern understandings shaping the field. Explore differential diagnosis, uncovering alternative etiologies and current diagnostic criteria, while shedding light on biomarkers and novel diagnostic tests revolutionizing patient assessment. Contents will also guide readers through the utility of point-of-care ultrasound in intravascular volume assessment sets the stage for exploring medical therapy options, including vasoconstrictors and albumin usage. Written by a team of experts, this comprehensive reference highlights the intricate pathophysiology of hepatorenal syndrome while delivering the most up-to-date insights into diagnostic and therapeutic approaches. Historically overshadowed by grim prognoses, hepatorenal syndrome has undergone a renaissance of interest due to recent breakthroughs, revolutionizing treatment paradigms. Whether you're a seasoned practitioner or a burgeoning researcher immersing yourself in this dynamic field, this resource offers a thorough examination, encompassing novel diagnostic criteria, innovative biomarkers, and state-of-the-art treatments.

  • Adverse Childhood Experiences

    Using Evidence to Advance Research, Practice, Policy, and Prevention
    • 2nd Edition
    • Gordon J. G. Asmundson + 1 more
    • English
    The second edition of “Adverse Childhood Experiences: Using Evidence to Advance Research, Practice, Policy, and Prevention” delves deeper into the foundational ACEs Study, providing a thorough review alongside comprehensive definitions and assessment methodologies. From mental and physical health outcomes to the neurodevelopmental mechanisms linking ACEs to psychopathology, sexual violence, and sexual health outcomes, this edition presents a nuanced understanding of the complex interplay between adverse experiences and lifelong consequences. Newly incorporated content addresses contemporary issues, redefining ACEs, exploring the appropriateness of routine screening, and contemplating ACEs from a global perspective. Professionals working with children and families, including physicians, nurses, social workers, psychologists, lawyers, judges, public health leaders, policy makers, and government delegates, will find this evidence-based resource invaluable. "Adverse Childhood Experiences" not only equips practitioners with the latest research findings but also presents strategies for preventing ACEs, fostering trauma-informed care, resilience, and emphasizing the crucial role of safe, stable, and nurturing environments for children. This second edition cements its status as an indispensable guide, addressing the evolving landscape of ACEs with precision and relevance.

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