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Elsevier

Academic Press

  • Basic Principles of Drug Discovery and Development

    • 3rd Edition
    • Benjamin E. Blass
    • English
    **Selected for 2026 Doody's Core Titles in Pharmacy**Basic Principles of Drug Discovery and Development, Third Edition presents a unique overview of the drug discovery and development program not available elsewhere. Each chapter provides sufficient technical details on the topics covered so that non-experts will have the tools and information necessary to interact and exchange information with colleagues across the entire spectrum of the drug discovery and development process. The drug discovery and development process involves individuals and teams with a wide array of expertise ranging from basic sciences (medicinal chemistry, biology) to applied science (pharmacology, pharmacokinetics, clinical sciences) to business driven fields (regulatory affairs, intellectual property experts, marketing specialists).The success or failure of a program focused on bringing a new medication to market often depends on clear communication between individuals and teams with vastly different expertise. As a result, it is critical that experts in one aspect of drug discovery and development (e.g., medicinal chemists) have a working understanding of the wide range of disciplines that take part in the overall process.

  • Neuroscience-Informed Psychoeducation (NIPE) for Brain and Mental Health

    Part D
    • 1st Edition
    • Volume 305
    • English
    Neuroscience-Informe... Psychoeducation (NIPE) for Brain and Mental Health series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Methods in Systems Bioinorganic Chemistry

    • 1st Edition
    • Volume 741
    • English
    Methods in Systems Bioinorganic Chemistry, Volume 741 provides understanding of high-level properties involving metals in biology that are founded on molecular or mechanistic level interactions. Currently, there is no established “tool kit” for studying bioinorganic systems, so the methods included in the book span a diverse range of topics and approaches, from imaging to proteomics, from metals-in-mice to mathematical modeling. Specific chapters cover Inductively Coupled Plasma Mass Spectrometry (ICP-MS)-based methods to quantify transition metals in cells and vertebrate models, ICP-MS elemental analysis in tissue samples, and much more.Additional chapters delve into An inductively-coupled-... triple quadrupole method with oxygen for the determination of essential elements and protein concentration, Calculating metal speciation of proteins inside cells, Probing biological copper in the subfemtomolar regime, Using LC-ICP-MS chromatography to detect and characterize Labile Metal Pools, Linking dynamic bioinorganic chemistry processes of toxic metals in the bloodstream to establish their exposure-response relationship in humans, Contextualizing X-ray fluorescent microscopy – high resolution X-rays meet subcellular morphology, Chemoproteomic profiling of transition metal binding sites in bacterial proteomes, Heme Labeling by Proximity (HeLP) to Identify Hemoproteins, and much more.

  • Flavoproteins and Flavoenzymes

    • 1st Edition
    • Volume 740
    • English
    Flavoproteins and Flavoenzymes, Volume 738 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Kirisu2 and KiPaD: global analysis of rapid flavoprotein redox kinetics from stopped-flow multi, ilagros Mendina, A Generic First Approach to Dissecting Flavoenzyme Catalytic Cycles, Removing Covalent Constraints of Protein Loops and Lids by a Split-Gene Strategy, Designing Oxygen Reaction Sites in Flavoprotein Dehydrogenases, Converting Noncovalent Flavoproteins into Covalently Flavinylated Proteins, Complexities of Riboflavin Biosynthesis, Reactions of Riboflavin Catabolism, and much more.Additional sections cover Ferredoxin-dependent thioredoxin reductase, Thermophilic Methylenetetrahydrof... Reductases, Ion-Pumping NADH:Quinone Oxidoreductase, Loading E. coli Dihydroorotate Dehydrogenase with Coenzyme Q, and Single-Component Halogenases.

  • Blockchain-Enabled Innovations in Location-Based Services for Healthcare

    • 1st Edition
    • Ajay Kumar Gupta + 3 more
    • English
    Blockchain-Enabled Innovations in Location-Based Services for Healthcare addresses the growing need for secure, intelligent healthcare solutions integrating location-based services (LBS), Internet of Things (IoT), and blockchain technologies. This reference explores how these technologies transform healthcare delivery improving autonomy and real-time care while safeguarding sensitive data. It responds to the challenges posed by the proliferation of wearable sensors and smart medical devices by proposing decentralized, privacy-preserving frameworks.The book’s comprehensive chapters cover blockchain trust models, adaptive privacy for patient trajectories, wearable computing, deep learning for medical imaging, secure communication in healthcare IoT, and AI-powered diagnostics. Contributions from global experts provide case-driven analyses and technical depth, addressing current challenges in healthcare data security, interoperability, and predictive modeling. The interdisciplinary approach integrates computer science, data privacy, and healthcare informatics, making it a valuable resource for researchers and professionals.Blockc... Innovations in Location-Based Services for Healthcare benefits academic researchers, industry practitioners, graduate students, and policymakers by offering cutting-edge knowledge in secure, decentralized healthcare systems. It equips readers with advanced methodologies and practical solutions to design inclusive healthcare technologies, fostering innovation in smart health monitoring, medical image analysis, and data-driven diagnostics within privacy-compliant frameworks.

  • Engelking's Textbook of Veterinary Physiological Chemistry

    • 4th Edition
    • Kevin Connolly
    • English
    Bridging the gap between basic and clinical science concepts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition offers broad coverage of biochemical principles for students and practitioners of veterinary medicine. The only recent biochemistry book written specifically for the veterinary field, this updated text covers cellular-level concepts related to whole-body physiologic processes in a reader-friendly, approachable manner. Each chapter is written in a succinct and concise style that includes an overview summary section, numerous illustrations for best comprehension of the subject matter, targeted learning objectives, and end of the chapter study questions to assess understanding.With numerous illustrations and both instructor and student companion websites with updated PowerPoint images, lecture slides, and Snapcasts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition, proves useful to students and lecturers from diverse educational backgrounds. Sectional exams and updated case studies extend the breadth and depth of learning resources.

  • Synthetic Polymer Chemistry

    • 1st Edition
    • Pradip Bhowmik
    • English
    Synthetic Polymer Chemistry provides a comprehensive introduction to polymers and their physical properties, as well as different types of polymerization reactions. The book covers an array of integral topics, from the introduction of polymers and their physical properties, to morphology (crystalline and amorphous phase), and molecular weights measurements and solubility. Different types of polymerization reactions (free radical, cationic, anionic condensation) based on organic reaction mechanisms are also discussed. Users will find this book to be a great resource for students and researchers who want to build a strong foundation of organic chemistry and polymer chemistry.Topics discussed in this resource will provide an important foundation and understanding that helps readers grasp the materials covered in advanced polymer chemistry. It is ideal for courses in polymer chemistry, organic chemistry, materials science and engineering, and biomedical engineering.

  • An Introduction to Quantum Physics

    From Schrodinger's Equation to Quantum Computing
    • 1st Edition
    • Michael I. Bergman
    • English
    An Introduction to Quantum Physics: From Schrodinger’s Equation to Quantum Computing develops physical insight and introduces a few mathematical techniques to make quantum physics accessible and engaging. The book introduces the Schrodinger wave equation, solving classic problems such as the infinite square well and the quantum harmonic oscillator, before solving for the electronic structure of the hydrogen atom. It also provides intuition into the famous Heisenberg uncertainty principle, and uses the Pauli exclusion principle to explain the origin of the periodic table. Unusual for an introductory quantum physics text, the book then introduces matrix mechanics for spin, which leads to more recent work on entanglement, Bell’s theorem, and elements of quantum computing. The book explores rigorously philosophical issues that are now experimentally testable, which students find compelling and have become of practical importance. The text makes a point to connect physics, chemistry, mathematics, and computer science. Through clear and entertaining text, ample figures, worked examples, and thoughtful homework problems, the book builds physical intuition and skill at problem solving.

  • Structural Biology of Amyloid Fibrils

    • 1st Edition
    • Vijay Kumar + 1 more
    • English
    Structural Biology of Amyloid Fibrils provides a comprehensive reference on the structure of protein aggregates in different neurodegenerative diseases, along with their molecular bases. Chapters describe these structures in detail, highlighting their similarities and differences across different disease states along with an unprecedented overview of current developments and new hypotheses emerging in amyloid fibril structure, stability and mechanisms of formation. The book also discusses how amyloid structure may affect the ability of fibrils to spread to different sites in a prion-like manner, as well as their role in disease. Featuring chapters on NMR, X-ray crystallography, and Cryo-EM methods, and discussing the structure of amyloid fibrils obtained directly from patients, the book allows readers to understand how polymorphism is associated with disease phenotype and how fibril structure affects and influences the cellular environment. Understanding the molecular architecture of amyloid fibrils and oligomers will be an important step towards developing therapeutic interventions based on targeting the fibrils and oligomers themselves and the processes that generate them.

  • Advances in Inorganic Chemistry

    • 1st Edition
    • Volume 88
    • English
    Advances in Inorganic Chemistry, Volume 88 continues this highly regarded series, highlighting recent developments in the field. This volume features authoritative reviews written by an international board of authors, providing advanced researchers with comprehensive and fully referenced content. The focus of this new release centers around Lantern-Type Complexes of the Frist Row Transition Metals: Experimental and Computational Insights into Ground State Metal-Metal Bond Lengths and Bond Orders.As with previous volumes, the book includes an index and serves as an indispensable reference in inorganic chemistry.

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