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    • Novel Therapeutic Approaches Targeting Oxidative Stress

      • 1st Edition
      • February 18, 2022
      • Pawan Kumar Maurya + 1 more
      • English
      • Paperback
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      • eBook
        9 7 8 0 3 2 3 9 0 9 0 6 8
      Novel Therapeutic Approaches Targeting Oxidative Stress investigates the role of oxidative stress in disease and explores the latest methods and approaches to targeting oxidative stress for treatment and diagnosis. The book begins with an introduction to oxidative stress and its significance. Subsequent sections cover biochemical methods for detecting free radicals and novel therapeutic approaches for targeting oxidative stress in a number of different diseases. This includes age-related illnesses, neuropsychiatric disorders such as schizophrenia and bipolar disorder, and neurodegenerative diseases like Alzheimer’s and Parkinson’s disease. Novel approaches for targeting oxidative stress in cancer and cardiovascular diseases are also explored. The book then moves on to discuss advances in drug delivery systems and detecting oxidative stress biomarkers using biosensors. It concludes with case studies that illustrate the targeting of oxidative stress and future perspectives.

    • 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine

      • 2nd Edition
      • February 18, 2022
      • Lijie Grace Zhang + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 2 4 5 5 2 1
      • eBook
        9 7 8 0 1 2 8 2 4 5 5 3 8
      3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine, Second Edition provides an in-depth introduction to bioprinting and nanotechnology and their industrial applications. Sections cover 4D Printing Smart Multi-responsive Structure, Cells for Bioprinting, 4D Printing Biomaterials, 3D/4D printing functional biomedical devices, 3D Printing for Cardiac and Heart Regeneration, Integrating 3D printing with Ultrasound for Musculoskeletal Regeneration, 3D Printing for Liver Regeneration, 3D Printing for Cancer Studies, 4D Printing Soft Bio-robots, Clinical Translation and Future Directions. The book's team of expert contributors have pooled their expertise in order to provide a summary of the suitability, sustainability and limitations of each technique for each specific application. The increasing availability and decreasing costs of nanotechnologies and 3D printing technologies are driving their use to meet medical needs. This book provides an overview of these technologies and their integration.

    • MicroRNA in Human Malignancies

      • 1st Edition
      • February 17, 2022
      • Massimo Negrini + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 2 8 7 4
      • eBook
        9 7 8 0 1 2 8 2 3 2 7 4 3
      MicroRNA in Human Malignancies offers a deep overview of the role and translational significance of miRNAs in the development of cancer and other malignancies. The book establishes the foundations of the field by covering essential mechanisms and the translational potential of miRNAs in the field of oncology. Specific topics covered include invasion and metastasis, miRNAs and metabolism, and opportunities of miRNAs in therapeutics. Chapters on diseases include content on disease-related pathophysiology, as well as diagnostic, prognostic and predictive value. This book is an essential reference for students entering the field, as well as researchers and investigators.

    • Xenobiotics in Chemical Carcinogenesis

      • 1st Edition
      • February 17, 2022
      • Akhileshwar Kumar Srivastava + 3 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 5 6 0 2
      • eBook
        9 7 8 0 3 2 3 9 0 6 8 1 4
      Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology covers the translational toxicology of xenobiotics substances in carcinogenesis by explaining the toxicokinetic and toxicodynamic, toxicogenomic, biotransformation, and resistance mechanisms in the human body. The book begins with a historical review and link to future prospects for chemical carcinogenesis. It discusses major environmental xenobiotics and their risks in inducing cancer, along with content on toxic xenobiotics and their routes of exposure in humans, the role of xenobiotic metabolism in carcinogenesis, and the toxicokinetic and toxicodynamic of xenobiotics in cancer development. Lastly, the book explores current achievements such as using toxicogenomics for predicting the carcinogenicity of xenobiotic substances and the challenges posed by carcinogenic xenobiotic substances when examining preventive methods, diagnosis, and the development of anticancer drugs for specific toxicants.

    • Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

      • 1st Edition
      • February 17, 2022
      • Michael Fehlings + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 9 8 3 5 3
      • eBook
        9 7 8 0 1 2 8 1 9 8 3 6 0
      Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout. These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma.

    • Hormones, Regulators and Hippocampus

      • 1st Edition
      • Volume 118
      • February 16, 2022
      • Gerald Litwack
      • English
      • Hardback
        9 7 8 0 3 2 3 9 9 2 2 1 3
      • eBook
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      Hormones, Regulators and Hippocampus, Volume 118 in the Vitamins and Hormones serial highlights new advances in the field, with this new volume presenting interesting chapters, including Thyroid hormone regulation of adult hippocampal neurogenesis – putative molecular and cellular mechanisms, Synergistic gene regulation by thyroid hormone and glucocorticoid in the hippocampus, Oxytocin and vasopressin in the hippocampus, Steroid hormones and hippocampal neurogenesis in the adult mammalian brain, Steroidogenic enzymes in the hippocampus: transcriptional regulation aspects, Ectonucleotidases in the hippocampus: spatial distribution and expression after ovariectomy and estradiol replacement, and much more.

    • Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 1

      • 1st Edition
      • February 16, 2022
      • Ganji Purnachandra Nagaraju + 1 more
      • English
      • Hardback
        9 7 8 0 3 2 3 9 8 8 0 6 3
      • eBook
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      Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume One: Biology and Pathophysiology provides comprehensive information about ongoing research and clinical data surrounding liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. This volume discusses topics such as tumor microenvironment in hepatocellular carcinoma, endoplasmic reticulum stress and unfolded protein response, effects of cirrhosis and hepatitis on the prognosis of HCC, mitochondrial metabolism, next generation sequencing, and telomerase. In addition, it discusses exosomes role in HCC progression, metastasis and chemokines. This is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer for their research work or clinical setting.

    • System Assurances

      • 1st Edition
      • February 16, 2022
      • Prashant Johri + 4 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 2 4 0 3
      • eBook
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      System Assurances: Modeling and Management updates on system assurance and performance methods using advanced analytics and understanding of software reliability growth modeling from today’s debugging team’s point-of-view, along with information on preventive and predictive maintenance and the efficient use of testing resources. The book presents the rapidly growing application areas of systems and software modeling, including intelligent synthetic characters, human-machine interface, menu generators, user acceptance analysis, picture archiving and software systems. Students, research scholars, academicians, scientists and industry practitioners will benefit from the book as it provides better insights into modern related global trends, issues and practices.

    • Digestive System Malignancies

      • 1st Edition
      • February 16, 2022
      • Constantine P. Spanos
      • English
      • Paperback
        9 7 8 0 3 2 3 9 8 3 6 9 3
      • eBook
        9 7 8 0 3 2 3 9 8 5 7 5 8
      Digestive System Malignancies provides an up-to-date overview on the most relevant diagnostic techniques, staging of malignancies, and current therapeutic modalities for digestive system malignancies. With coverage from esophageal, gastric and pancreatic cancers, to colon, anal and peritoneal surface, this reference offers a wide-ranging guide to malignancies throughout the digestive system. The use of engaging infographics provides an "at-a-glace" perspective on the subject, allowing users to retain a large amount of information without scrolling through large text or complex algorithms. This is an important reference for clinicians, surgeons, medical students and scientists that need a quick reference on digestive system malignancies.

    • Rhizosphere Engineering

      • 1st Edition
      • February 15, 2022
      • Ramesh Chandra Dubey + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 8 9 9 7 3 4
      • eBook
        9 7 8 0 3 2 3 8 8 5 9 5 9
      Rhizosphere Engineering is a guide to applying environmentally sound agronomic practices to improve crop yield while also protecting soil resources. Focusing on the potential and positive impacts of appropriate practices, the book includes the use of beneficial microbes, nanotechnology and metagenomics. Developing and applying techniques that not only enhance yield, but also restore the quality of soil and water using beneficial microbes such as Bacillus, Pseudomonas, vesicular-arbuscular mycorrhiza (VAM) fungi and others are covered, along with new information on utilizing nanotechnology, quorum sensing and other technologies to further advance the science. Designed to fill the gap between research and application, this book is written for advanced students, researchers and those seeking real-world insights for improving agricultural production.

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