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Elsevier

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

  • 1st Edition - February 17, 2022
  • Latest edition
  • Editors: Michael Fehlings, Brian Kwon, Alexander R. Vaccaro, F. Cumhur Oner
  • Language: English

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerat… Read more

Description

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout.

These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma.

Key features

  • Contains contributions by international authors
  • Covers recent clinical trial advancements and findings and updates on ongoing trials
  • Presents an overview of clinical practice guidelines for the management of traumatic spinal cord injury featured
  • Provides the reader with insights regarding the translation of research from bench to bedside and the skills needed to understand the translational pathway using real-life examples

Readership

Clinical Spine Fellows; Residents; Neurosurgeons; Clinical and Basic Researchers; Orthopaedic Surgeons; Critical Care Specialists; Medical Students; Rehabilitation Specialists

Table of contents

1. Anatomy (touch on both spine trauma and SCI)

2. Epidemiology

3. Classification Systems: Spine Trauma

4. Classification Systems: SCI

5. Outcome Measures

6. Imaging: Spine Trauma

7. Imaging: SCI (include advanced imaging techniques)

8. Intraoperative imaging and Image Guidance

9. Spine Trauma Management Issues: Upper C-spine

10. Spine Trauma Management Issues: C-spine

11. Spine Trauma Management Issues: Thoracic and Lumbar

12. Spine Trauma Management Issues: Sacrum

13. Spine Trauma Management Issues: Polytrauma

14. Spine Trauma Management Issues: Geriatric

15. Spine Trauma- areas of controversy and emerging concepts

16. Traumatic Central Cord Injury

17. SCI Management: Pathophysiology

18. SCI Management: Role and Timing of Surgical Intervention

19. SCI Management: ICU Management (including MPSS) + Drugs

20. SCI Management: Rehabilitation

21. SCI Management: Economic Impact

22. Complications

23. Neurochemical Biomarkers of Acute Spinal Cord Injury

24. Clinical Trials: Drugs

25. Clinical Trials: Regenerative Approaches

26. Clinical Trials: Rehabilitation Approaches

27. Translational Perspective: Neuroprotective Strategies for Traumatic Spinal Cord Injury

28. Translational Perspective: Neuroregenerative Strategies for Traumatic Spinal Cord Injury

29. Emerging Concepts in the clinical management of SCI for the future

30. Translational Research in Spinal Cord Injury: What is in the Future?

Review quotes

“...focuses on understanding and developing strategies to promote the healing and recovery of the nervous system following damage to the spinal cord or spine…. [A]ims to summarize critical advancements in the SCI field, while providing great detail and creating a solid foundation for the current body of knowledge…. [and] covers a wide range of topics related to SCI, regeneration, and clinical practice guidelines…. The topics are well organized into chapters, which are complementary to one another and create a good flow of information...[A] comprehensive and valuable resource for individuals interested in the field of SCI and neural repair.” —©Doody’s Review Service, 2023, Morteza Sadeh, MD PhD (University of Illinois at Chicago College of Medicine)

Product details

  • Edition: 1
  • Latest edition
  • Published: February 17, 2022
  • Language: English

About the editors

MF

Michael Fehlings

Dr. Fehlings is the Vice Chair Research for the Department of Surgery at the University of Toronto and Head of the Spinal Program at Toronto Western Hospital, University Health Network. Dr. Fehlings is a Professor of Neurosurgery at the University of Toronto, holds the Gerry and Tootsie Halbert Chair in Neural Repair and Regeneration, is a Scientist at the McEwen Centre for Regenerative Medicine and a McLaughlin Scholar in Molecular Medicine. He is currently Co-Director of the University of Toronto Spine Program and combines an active clinical practice in complex spinal surgery with a translationally oriented research program focused on discovering novel treatments to improve functional outcomes following spinal cord injury.

Affiliations and expertise
Robert Campeau Family Foundation-Dr. CH Tator Chair in Brain and Spinal Cord Research

BK

Brian Kwon

Dr. Kwon is a surgeon-scientist with advanced training in spine surgery and also a PhD in neuroscience. He is a Professor in the UBC Department of Orthopaedics. As an attending orthopaedic spine surgeon at Vancouver General Hospital his practice is focused on the management of adult spine trauma, spinal cord injuries, and non-traumatic conditions such as spine infection, deformity, and degeneration. As a neuroscientist and Principal Investigator at ICORD, Dr. Kwon runs an active basic/translational research laboratory. Dr. Kwon is currently also serving as the Associate Director, Clinical Research, for ICORD, and is the Associate Scientific Director of the Rick Hansen Institute.
Affiliations and expertise
Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, Canada

AV

Alexander R. Vaccaro

Dr. Vaccaro has served as the president of Rothman Orthopaedics since 2014 and is the Richard H. Rothman Professor and Chairman in the Department of Orthopaedic Surgery and Professor of Neurosurgery at Thomas Jefferson University in Philadelphia, Pennsylvania. He was the recipient of the Leon Wiltse award given for excellence in leadership and clinical research for spine care by the North American Spine Society (NASS) and is the past President of Cervical Spine Research Society (CSRS), the American Spinal Injury Association and the Association for Collaborative Spine Research. He is currently a member of the American Academy of Orthopaedic Surgeons (AAOS) Board of Directors. He has over 900 peer-reviewed and 200 non-peer reviewed publications. He has published over 372 book chapters and is the editor of over 63 textbooks and co-editor of OKU-Spine I and editor of OKU-8. Dr. Vaccaro also serves as Co-Director of the Regional Spinal Cord Injury Center of the Delaware Valley.
Affiliations and expertise
Richard H. Rothman Professor and Chairman, Department of Orthopaedic Surgery, Professor of Neurosurgery, Sidney Kimmel Medical Center of Thomas Jefferson University, Co-Director, Delaware Valley Spinal Cord Injury Center, President, Rothman Orthopaedics, Philadelphia, Pennsylvania, USA

FO

F. Cumhur Oner

Cumhur Öner obtained in 1980 his Medical Degree in Ankara, Turkey and did his orthopaedic surgery training in Rotterdam between 1987 and 1993. Since 1993 he works as an orthopaedic spine surgeon at the University Medical Centre Utrecht. He obtained his PhD (cum laude) in 1999 from the University of Utrecht. The work for his PhD thesis focused on the diagnostic and prognostic parameters in spinal trauma patients. He is the head of the neuro-orthopaedic spine unit since 2002. Cumhur Öner has actively participated in the foundation of the international Spine Trauma Study Group and is currently member of the steering committee of the Knowledge Forum Trauma of the AOSpine International. He has been involved in clinical spine research as well as the bone and intervertebral disc RM program in the UMC Utrecht. He was the president of the Dutch Spine Society between 2007-2011.
Affiliations and expertise
University Medical Centre Utrecht, Utrecht, The Netherlands

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