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Academic Press

  • Two Sides of Nanovaccines and Nanomedicines in Cancer Treatments

    • 1st Edition
    • Tuan Anh Nguyen + 2 more
    • English
    Two Sides of Nanovaccines and Nanomedicines in Cancer Treatments provides a balanced exploration of the dual roles of nanotechnologies in oncology. Structured in four parts, the book begins with foundational knowledge of nanovaccines and nanomedicines, detailing their applications in cancer care and highlighting their precision in targeting cancer cells while reducing systemic toxicity. Importantly, the book addresses potential drawbacks, discussing side effects and safety concerns associated with these innovations. The final section emphasizes ethical, regulatory, and safety challenges, underscoring the need for careful oversight as nanotechnologies advance. For the academic audience, this book serves as a vital resource, offering insights that equip researchers and healthcare professionals to make informed decisions regarding clinical applications. Its focus on both the benefits and risks, alongside forward-looking perspectives, ensures that readers are well-prepared for future developments in the field of nanomedicine and cancer therapy.
  • Revolutionizing Cancer Treatment

    The Power of Molecularly Imprinted Polymers for Precision Therapy
    • 1st Edition
    • Bhupendra G. Prajapati + 3 more
    • English
    Revolutionizing Cancer Treatment: The Power of Molecularly Imprinted Polymers for Precision Therapy examines the transformative role of molecularly imprinted polymers (MIPs) in cancer management and treatment. This comprehensive book explores how MIPs can be utilized to create advanced drug delivery systems specifically targeting various cancer types, including breast, prostate, and lung cancers, among others. By integrating molecular imprinting techniques with precision oncology, this resource provides valuable insights for researchers, clinicians, and pharmaceutical developers aiming to enhance cancer therapies. Structured in a user-friendly format, the book includes detailed chapters dedicated to specific cancer types, highlighting the design and application of MIPs in targeted therapies. Users will find flow charts, process diagrams, and case studies to facilitate understanding of complex concepts. The necessity for this book arises from the pressing demand for precision medicine in oncology, as conventional treatments often suffer from issues of specificity and efficacy. Ultimately, this work serves as a vital reference for students, researchers, and healthcare professionals dedicated to advancing cancer treatment through innovative drug delivery systems.
  • ESKAPE Pathogens

    Virulence, Resistance, and Management
    • 1st Edition
    • Karthikeyan Ramalingam
    • English
    ESKAPE Pathogens: Virulence, Resistance, and Management provides comprehensive coverage on ESKAPE pathogens, including their virulence mechanisms, resistance patterns, and challenges in their management. The book offers the latest information on ESKAPE pathogens' pathogenicity, mechanisms of antibiotic resistance, and innovative approaches to manage these pathogens. It explores recent advancements in the field of genomics, proteomics, and transcriptomics that could potentially provide valuable insights into the mechanisms and genetic basis of antibiotic resistance in ESKAPE pathogens. Finally, the book highlights the need for alternative treatment options and innovative management strategies to combat the emergence of multidrug-resistant strains.This is a helpful resource to researchers, clinicians, educators, industry professionals, and advanced students interested in the latest research and strategies for combating multidrug-resistant pathogens.
  • Structural Study of Amyloid-β

    • 1st Edition
    • Volume 729
    • English
    Structural Study of Amyloid-β, Volume 729 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on important topics such as the Extraction of Amyloids from Neurodegenerative Disease Tissues for Structural Analysis, Cryo-EM Structure Determination of Amyloid Fibrils: Methodology, Insights, and Practical Tools, Methods for studying molecular architecture of Ab aggregates in tissues using cryo-ET, Cryo-EM methods to study binding between amyloid fibrils and chemical compounds or ligan, Dynamics studies of side-chains and hydration shells in amyloid-beta fibrils using deuterium and oxygen-17 solid-state NMR, and much more.Additional chapters cover the Technical aspects of pressure jump NMR applied to the study of Abeta and protein oligomerization, Characterizations of the beta-amyloid-membran... interaction intermediates, Time-resolved solid-state NMR studies of oligomer formation, Methods for characterizing the individual filament structures of amyloid peptide assemblies using atomic force microscopy, Single-molecule fluorescence spectroscopy and imaging on heterogeneous amyloid beta aggregation, Two-dimensional FT-IR methods on amyloid aggregation and folding pathways, and much more.
  • Medical Device Design

    Innovation from Concept to Market
    • 3rd Edition
    • Peter J. Ogrodnik
    • English
    Medical Device Design: Innovation from Concept to Market, Third Edition provides the bridge between engineering design and medical device development. The book clearly explains the process of medical device development - from very early stages of conceptualization to commercialization on the global market. It addresses medical devices' regulatory (FDA and EU) requirements, shows the essential methodologies medical designers must understand to ensure their products meet requirements, and brings together proven design protocols, enabling engineers and medical device manufacturers to rapidly bring new products to the marketplace.This book is suitable for professional engineers, both new and experienced, as well as students taking a course in medical device design.
  • Artificial Intelligence for Multi-omics Analysis Part B

    • 1st Edition
    • Volume 222
    • English
    Artificial Intelligence for Multi-omics Analysis Part B, Volume 222 in the Progress in Molecular Biology and Translational Science series, highlights recent advances, with this new volume presenting chapters on a variety of topics, including Artificial Intelligence in multi-omics analysis of small molecule drug discovery, AI in multi-omics analysis in antimicrobial resistance, Artificial Intelligence and multi-Omics Approach in Vaccine Development, Artificial Intelligence in multi-omics Analysis of heart diseases, Artificial Intelligence in multi-omics Analysis of Kidney Diseases, Artificial Intelligence in multi-omics Analysis of Gastrointestinal Diseases, AI in multi-omics analysis in Stem cell research, and AI in multi-omics analysis in cancer, and more.Additional sections cover AI in multi-omics analysis in obstructive lung diseases, AI in multi-omics analysis in neurodiseases, AI in multi-omics analysis in autoimmune diseases, AI in multi-omics analysis of liver diseases, AI in multi-omics analysis of COVID-19 patient data, and AI in multi-omics analysis of Type 2 diabetes.
  • Developing Solid Oral Dosage Forms

    Pharmaceutical Theory and Practice
    • 3rd Edition
    • Yihong Qiu + 4 more
    • English
    Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Third Edition is a comprehensive and up-to-date guide for professionals and academics engaged in all aspects of oral dosage form development, from discovery support through commercial manufacturing. This new edition features 13 new or rewritten chapters, along with significant updates to existing content, reflecting the latest advancements in the field, including new theories, scientific findings, approaches, techniques, modeling, and the emerging opportunities offered by AI.This book consists of 44 chapters covering in-depth principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their applications throughout the R&D process and commercial production of oral dosage forms. New chapters address topics such as absorption evaluation of oral dosage forms, formulation principles, and applications based on supersaturation, patient-centric product design, product design through the 505(b)(2) NDA pathway, design of experiments (DoE), process modeling, 3D printing, and machine learning applications in commercial manufacturing. Existing chapters have been updated or completely rewritten to provide advanced information and include practical case studies. Important topics such as amorphous solid dispersions, modified-release delivery, manufacturing technologies, modeling and simulation, fundamentals of dissolution and bioequivalence, IVIVC, biowaivers, regulatory frameworks, and many others are covered.The new edition of this book is an indispensable resource for industry professionals, academic institutions, and regulatory bodies seeking to stay current with advances in solid dosage form development and manufacturing. It offers a thorough understanding of fundamental principles and techniques, along with practical guidance on applying these concepts to real-world challenges.
  • Women and Health

    • 3rd Edition
    • Rebecca Troisi + 3 more
    • English
    Women and Health addresses health issues affecting women of all ages — from adolescence through maturity. It goes far beyond other books on this topic, which concentrate only on reproductive health, and has a truly international perspective. It covers key issues ranging from osteoporosis to breast cancer and other cancers, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease and other chronic illnesses, substance abuse, and societal and behavioral influences on health.In this third edition of Women and Health, the chapters address health issues that affect women across the life course with a special emphasis on the health of mid-life and older women. The field of women’s health has matured since the first and second edition, such as genetics and the impact of sex and gender on health, providing the opportunity to capture the latest scientific findings and controversies. The book provides a comprehensive compendium of the epidemiology of health conditions affecting women over the life course for the lay reader, clinician, and health research scientist.
  • An Illustrated Guide to Cancer Biology

    • 1st Edition
    • Tomas Koltai + 1 more
    • English
    An Illustrated Guide to Cancer Biology offers a comprehensive exploration of the fundamentals of oncological molecular biology and provides valuable insights into topics such as cancer cell migration, chemotherapeutic drug mechanisms, and the roles of RNA in cancer. With 33 chapters covering a wide array of subjects, including the Hanahan and Weinberg hallmarks of cancer, tumor heterogeneity, and hormone-dependent cancer, this guide serves as an indispensable resource for researchers, students, and practicing oncologists in medicine, oncology, and biochemistry alike. This book stands out not only for its comprehensive coverage of diverse topics but also for its unique approach.With over 400 figures strategically interspersed throughout the text, this book offers readers a visually engaging journey through the intricacies of cancer biology. These illustrations, ranging from molecular pathways to cellular interactions, make navigating topics like chemotherapeutic drug mechanisms and tumor heterogeneity more accessible. Additionally, the inclusion of sections on repurposing drugs, tumor kinetics, and epigenetics further aids in a deep understanding of cancer biology.
  • Mindful Self-Care for Clinicians and Caregivers

    A Group Facilitator's Guide
    • 1st Edition
    • Martin Lumpkin + 2 more
    • English
    Clinicians and caregivers face high risks of burnout, stress, and emotional fatigue from the demands of giving care to those in need over time. Mindfulness-based interventions can promote self-care and reduce caregiver burden. Mindful Self-Care for Clinicians and Caregivers (MSCC) offers participants the opportunity to access the privileges of caregiving and to enhance resilience and well-being.This practical, evidence-based guide supports facilitators of groups focused on Mindful Self-Care for Clinicians and Caregivers . This guide is developed by experienced mental health professionals and scholars, and offers the following key features:Step-by-ste... session guides for in-person and virtual delivery of MSCCDownloadable resources: participant handouts, audio meditations, videos, and visual aidsFacilitation tips and strategies for common challengesCultural considerations and adaptable group structuresTheoretica... and empirical foundations including hypotheses and methods for researchers and studentsFlexible use for group facilitation or individual self-studyThe guide also explores the emotional demands of caregiving and offers models to understand and promote Mindful Self-Care for Clinicians and Caregivers. An online companion site provides multimedia support for facilitators.Whether used in clinical settings, in educating practitioners, or for personal growth, this guide promotes sustainable, compassionate caregiving and self-care through learning the fundamental skills of mindful practice.