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Academic Press

  • A Comprehensive Guide for Novice Researcher in Clinical Trials

    • 1st Edition
    • July 1, 2026
    • Miltiadis Lytras + 2 more
    • English
    A Comprehensive Guide for Novice Researcher in Clinical Trials is a must-have resource for individuals embarking on the journey of clinical research. This book is tailored for beginners, offering a clear and structured introduction to the vital principles, methodologies, and skills required to design and conduct robust clinical trials. Spanning 13 chapters, it meticulously covers the entire clinical trial process, emphasizing Good Clinical Practice (GCP) standards. From foundational research concepts to advanced trial strategies, the guide empowers readers to confidently navigate the complexities of clinical trials and contribute meaningfully to the field of healthcare.In addition to its foundational content, the book addresses a variety of important topics, such as ethical considerations, regulatory compliance, and the development of trial protocols. It explores different trial designs, types of bias, and the historical evolution of clinical research. Practical sections on data management, monitoring, statistical analysis, and project management offer readers hands-on guidance for real-world application. Notably, the book includes a dedicated focus on regulatory affairs in Saudi Arabia, making it particularly valuable for health professionals in that region.

  • Diagnosis and Analysis of Glaucoma using AI and ML for Medical Imaging

    • 1st Edition
    • July 1, 2026
    • Mohammad Sufian Badar
    • English
    Diagnosis and Analysis of Glaucoma using AI and ML for Medical Imaging highlights the importance of early detection while also discussing and updating on current treatment options to slow disease progression, emphasizing the role of AI and ML in improving diagnosis and management. Sections explore causes, symptoms, diagnostic challenges, and treatment strategies for glaucoma, integrating insights on how artificial intelligence and machine learning models can enhance healthcare delivery. Practical case studies and discussions on how accessible AI tools can be utilized by healthcare workers, NGOs, students, and researchers to address diagnostic barriers prevalent in resource-limited settings are included. This targeted resource is aimed at increasing understanding of this often asymptomatic, progressive eye disease, particularly in developing countries. Healthcare professionals, students, and policymakers will find this resource valuable with its straightforward, easy to understand, curriculum-aligned content. Its emphasis on practical applications and awareness-building make it a valuable tool for advancing glaucoma care and fostering interdisciplinary collaboration in eye health.

  • MRI of Brain Physiology

    Novel Methods and Clinical Applications
    • 1st Edition
    • June 30, 2026
    • Audrey P. Fan + 1 more
    • English
    MRI of Brain Physiology: Novel MRI Methods and Clinical Applications delves into the intricate world of brain physiology, focusing on the latest magnetic resonance imaging (MRI) methods and their clinical applications. Designed for biomedical engineers, technologists, radiologists, neurologists, neurosurgeons, and clinical researchers, this resource bridges the gap between advanced imaging techniques and practical clinical use. It covers a wide spectrum of cerebral physiology, from microvascular and macrovascular dynamics to cerebrovascular reserve, neurovascular coupling, and cerebrospinal fluid pathways. Each of the core chapters has a tripartite structure: physiology (concepts of the physiological processes), imaging techniques, and clinical applications. Readers will find detailed discussions on emerging MRI methods, including dynamic contrast, arterial spin labeling, and quantitative BOLD models. The book also addresses the functional impact of physiological changes on tissue microstructure and integrity, offering insights into multiparametric relaxation mapping and quantitative susceptibility mapping. Uniquely, this book gives a comparative approach to different brain physiological MRI methods, highlighting their strengths, limitations, and reliability.

  • Proteostasis and Cancer

    • 1st Edition
    • June 20, 2026
    • Buddhi Prakash Jain
    • English
    Proteostasis and Cancer explores the intricate mechanisms of protein homeostasis and their critical roles in cancer progression and therapeutics. The book delves into the mechanisms that control proteins inside the cell to preserve the health of the cellular proteome and the organism itself. It covers key topics such as post-translational modifications, protein folding, proteolysis, and the unfolded protein response (UPR), with a specific focus on their roles in cancer. Detailed discussions on molecular chaperones, the ubiquitin-proteasome system, and autophagy pathways offer valuable insights into how these processes contribute to cancer progression and how they can be targeted for therapeutic interventions.With clear explanations and well-labeled diagrams, the book makes complex concepts accessible to students and researchers alike. It also addresses the clinical implications of proteostasis in cancer, providing a foundation for developing innovative, therapeutic strategies. The book's multidisciplinary approach, combining insights from biochemistry, cancer biology, and medical sciences make it an essential resource for anyone seeking to understand the role of proteostasis in cancer.

  • Moving Toward Nonanimal Approaches in Medical Research and Testing

    • 1st Edition
    • June 16, 2026
    • Gail A. Van Norman + 1 more
    • English
    Moving Toward Nonanimal Approaches in Medical Research and Testing pioneers a single-source guide for researchers regarding nonanimal research tools and methodologies and their many advantages and applications in place of animals. This book is presented in three parts: historical, ethical, legislative, and scientific contexts on the need to shift away from animal-based research and testing; the latest advances in nonanimal tools and methods for biomedical research and testing of human therapeutics and other compounds, including microphysiological systems, bioprinting, biobanks, and artificial intelligence; and achieving a practical shift toward these powerful approaches, including advocacy for legal, regulatory, and policy change, securing funding for nonanimal studies, and how to overcome bias against nonanimal methods. This book, primarily directed to researchers in biomedicine, human medical therapeutics, and toxicology, will also appeal to researchers in industry, providing overview and insights about the latest applications of nonanimal research tools and methods for product development and testing. Clinicians who wish to understand the reliability of testing therapeutics with nonanimal versus animal methods, as well as advocacy groups seeking an up-to-date understanding of ethical, economic, political, and scientific considerations in moving toward nonanimal approaches, will also find significant value in this text. Finally, legislators and those involved in regulatory review and oversight will benefit from this single comprehensive source for developing a basic understanding of nonanimal research and human safety.

  • Neuromorphic Computing for Brain Computer Interfaces

    Enhanced Synergies in Mind and Machine
    • 1st Edition
    • June 15, 2026
    • Seifedine Kadry + 3 more
    • English
    Neuromorphic Computing for Brain Computer Interfaces: Enhanced Synergies in Mind and Machine examines practical situations where interpretability is crucial, going beyond theoretical considerations and providing case studies and examples to illustrate how Brain Computer Interfaces could be implemented in the real world. The book encompasses novel concepts, cutting-edge research, frameworks, and tools that facilitate comprehension of neuromorphic computing models. It is an ideal, comprehensive reference for professionals, researchers, and students who want to grasp the fundamental concepts and most recent developments in brain-computer interfaces (BCIs) and neuromorphic computing.

  • Laboratory Animal Medicine

    • 4th Edition
    • June 12, 2026
    • James G. Fox + 4 more
    • English
    Laboratory Animal Medicine, Fourth Edition—a volume in the American College of Laboratory Animal Medicine (ACLAM) blue book series—is the authoritative reference on the biology, health, and care for species involved in research. Edited by recognized veterinary, operational, and research experts and endorsed as the official material for veterinary specialty certification by ACLAM, this work defines the standard for all aspects of humane laboratory animal care and science with animal models.This new edition contains significant changes in content and organization to reflect the evolution of the field. The animal welfare chapter has been moved to the beginning of the book to highlight this subject’s importance. Other chapters have either been consolidated to encourage the reader to recognize commonalities such as those between guinea pigs, gerbils and hamsters, or separated out in recognition of expansions in knowledge and cross-species complexity as illustrated by separate new and old world primate chapters. Advances in practice, technology, and knowledge are highlighted in the chapters on genetically modified organisms, with updates on new techniques in genetic engineering and consideration of non-rodent genetically modified models; microbiological monitoring, with an increased emphasis on environmental monitoring and sentinel free colony health monitoring methods; regulatory compliance, with a comprehensive chapter on birds; employee health and safety, with expanded consideration of compassion fatigue; and animal models in biomedical research, with increased emphasis on experimental design and rigor. New chapters on animal models for microbiome, infectious disease, and transplant research have been added to serve as a reference for the community.This book is an excellent reference for veterinarians and research scientists, as well as program directors and facility managers employed in a variety of academic and corporate settings. This edition continues the tradition of this text in setting standards for the research animal science community as well as expanding and updating relevant and essential topics for this specialty field.

  • Basic Microbiology

    History, Fundamentals and Insights
    • 1st Edition
    • June 5, 2026
    • Saurabh Bhatia + 2 more
    • English
    Basic Microbiology: History, Fundamentals and Insights offers an exploration of the microbiology, providing a foundation in the study of microorganisms and their impact on health and disease. Beginning with an introduction to microbiology, the book covers the metabolism of microorganisms, revealing the biochemical processes that sustain microbial life. It then examines microbial genetics, uncovering the mechanisms of genetic variation and inheritance in microbes. Detailed chapters on bacteria, fungi, viruses, and protozoa provide thorough insights into the structure, function, and classification of these diverse organisms. The book also covers the principles of immunity, explaining the body’s defense mechanisms against microbial invasion. Finally, it addresses infection and diseases, highlighting the relationship between pathogens and human health. Ideal for students, educators, and professionals in microbiology and related field, Basic Microbiology: History, Fundamentals and Insights serves as an essential resource for understanding the microscopic world and its relevance to medicine and biology.

  • Glial Mechanisms in Sleep and Circadian Biology

    • 1st Edition
    • June 2, 2026
    • Marcos G. Frank
    • English
    Glial Mechanisms in Sleep and Circadian Biology presents a comprehensive and up-to-date discussion of the role of glial cells in numerous, often unexpected, aspects of sleep. It seamlessly links glial cell activity to the multi-system processes that affect sleep. Experts in the field discuss how glial cells influence the sleep-wake cycle, the accumulation and discharge of sleep drive, the timing of sleep and wake across the 24-hour day, and how glial cells may govern important sleep functions (e.g., brain plasticity and metabolism). This is a book that could well change scientists’ and practitioners’ traditional beliefs about the factors underlying sleep.Users will find the book's content at the forefront of one of the hottest topics in basic sleep research. Over the last decade, scientists have made breakthrough discoveries revealing that sleep is not only a product of neurons, but of neuronal-glial interactions.

  • A Modern Atlas for Implantable Devices of the Spine, Brain, and Nerve

    For Pain, Movement Disorders, and Nerve Dysfunction
    • 1st Edition
    • June 2, 2026
    • Timothy R. Deer + 1 more
    • English
    A Modern Atlas for Implantable Devices of the Spine, Brain, and Nerve: For Pain, Movement Disorders, and Nerve Dysfunction is an essential resource for healthcare professionals and researchers working in neuromodulation. This groundbreaking text focuses on the latest advancements in implantable technologies, exploring innovative techniques, frequencies, and neural targets that have revolutionized patient care. Covering a diverse range of conditions related to pain, movement disorders, and nerve dysfunction, the atlas provides a detailed overview of spinal, brain, and peripheral nerve procedures. It combines anatomical insights with clinical best practices to help professionals achieve enhanced outcomes in complex medical scenarios.In addition to introducing cutting-edge devices, the book delves into procedures like spinal cord stimulation and dorsal root ganglion modulation, offering a roadmap for navigating intricate anatomical and procedural landscapes. The atlas includes valuable sections on sacral nerve modulation and peripheral nerve stimulation, ensuring comprehensive coverage of neuromodulation's expanding possibilities. By bridging theoretical knowledge with practical application, this resource equips practitioners with the tools needed to address diverse patient challenges effectively.

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