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Academic Press

  • Hypercortisolism: Diagnosis and Differential Diagnosis

    • 1st Edition
    • Volume 132
    • June 1, 2026
    • English
    This volume outlines a comprehensive series of chapters focused on various aspects of endogenous hypercortisolism contributed by an international team of specialists in endocrinology. The following chapters are included in the volume: 1. Clinical presentation and comorbidities: Examines how Cushing's syndrome manifests and related health conditions; 2. Biochemical diagnosis of hypercortisolism: Details diagnostic approaches for hypercortisolism, including timing and methodology; 3. ACTH-independent Cushing syndrome: Focuses on diagnosis and causes of ACTH-independent forms; 4. Bilateral macronodular and micronodular hyperplasia: Covers biochemical, radiological, and genetic diagnosis; 5. Differential diagnosis between endogenous and pseudo-Cushing: Provides strategies to distinguish between true Cushing's and pseudoCushing; 6. Differential diagnosis of ACTH-dependent Cushing's syndrome: Discusses hormonal and imaging studies for distinguishing ACTH-dependent cases; 7. Ectopic Cushing's syndrome: Reviews clinical features and diagnosis of ectopic ACTH production; 8. Cyclic Cushing's syndrome: Presents the clinical course and diagnosis of cyclic forms; 9. Mild autonomous cortisol secretion: Explores diagnostic criteria for mild autonomous cortisol excess; 10.Cushing's syndrome in pregnancy: Describes presentation and diagnosis during pregnancy; 11.Molecular profile of Cushing's syndrome: Details genetic and molecular characteristics; 12. Cardiometabolic comorbidities in overt Cushing's syndrome: Discusses cardiovascular and metabolic risks associated with the syndrome; 13.New tools for diagnosis: Introduces innovative diagnostic methods for hypercortisolism.Eac... chapter is written by experts from leading medical institutions across Europe and Latin America. The chapters collectively offer a broad, in-depth exploration of Cushing's syndrome—from clinical presentation and differential diagnosis to molecular profiling and advances in diagnostic technology.
  • Pharmacology of T-Cell Therapies

    • 1st Edition
    • Volume 106
    • June 1, 2026
    • English
    Pharmacology of T-Cell Therapies, Volume 106 in the Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this new release include Enhancing persistence of therapeutic T cells, T cell manufacturing impacts on in vivo function, Transient T cell therapies, In vivo T cell therapies, T cell subsets for therapy, Engineering T cell metabolism to enhance therapeutic efficacy, and Tracking Therapeutic T cells In Vivo contacts.
  • Non-Stationary and Nonlinear Data Processing for Automated Computer-Aided Medical Diagnosis

    • 1st Edition
    • June 1, 2026
    • Rajesh Kumar Tripathy + 3 more
    • English
    Non-Stationary and Nonlinear Data Processing for Automated Computer-Aided Medical Diagnosis demonstrates the applications of machine learning and deep learning combined with signal processing techniques for human-machine interface applications using EMG signals. The book includes the analysis and classification of various heart diseases based on bio-signals like electrocardiogram (ECG), photoplethysmography (PPG), and phonocardiogram (PCG) signals. Various machine learning approaches, including advanced algorithms like multivariate signal processing, time-frequency analysis, and nonlinear signal processing are covered for CAD of neural, muscular, and cardiovascular diseases. The methods for CAD of various brain disorders are also included. Presented techniques utilize advanced non-stationary and nonlinear signal processing, along with machine learning and deep learning-based classification processes. CAD methods for diagnosing various neurological diseases are based on bio-signals such as electroencephalogram (EEG) and magnetoencephalogram (MEG), as well as medical images like magnetic resonance imaging (MRI) and computerized tomography (CT). Finally, the book addresses various types of medical signals and images, integrating nonlinear and non-stationary signal processing, machine learning, and deep learning within the CAD framework for diagnosing various diseases.
  • Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease

    • 1st Edition
    • June 1, 2026
    • Zahra Keshavarz Motamed + 2 more
    • English
    Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease explains how abnormal hemodynamics (blood flow dynamics) greatly alter the cardiovascular system’s ability to transport, control and maintain blood flow throughout the body. These deviations often lead to the initiation and progression of disease. Notably, hemodynamic quantification can be extremely useful for accurate and early diagnosis of cardiovascular disease. Particularly, the ability to monitor and predict hemodynamic effects following specific interventions can significantly broaden lifesaving options. However, image-based computational modelling of predictive hemodynamics analysis methods (and therefore new diagnostic tools) are rare. By extending quantitative methods of analysis, medical professionals can foresee effects of various cardiovascular interventions, allowing for optimized, situation-based care.Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease posits that novel, image-based computational modelling hemodynamic analysis tools will enable the next generation of diagnosis, predictive, and treatment planning resources for cardiovascular disease. Readers will become well-versed in recent advances in hemodynamic approaches, while preparing themselves for the next wave of revolutions in cardiovascular health.
  • ​​Abdominal Pain

    Essentials of Pathophysiology and Treatment
    • 1st Edition
    • June 1, 2026
    • Jakub Fichna
    • English
    Abdominal Pain: Essentials of Pathophysiology Treatment is the most up-to-date and comprehensive resource on abdominal pain. The book highlights new biomarkers, targets, and diagnostic techniques that are shaping the future of abdominal pain management, ensuring readers absorb the latest trends in diagnosis and treatment. By covering abdominal pain in the context of various specialties, it ensures a multidisciplinary understanding of these conditions for developing effective treatment strategies and improving patient outcomes. This first of its kind resource focuses on abdominal pain across numerous specialties, eliminating the need to search for information from innumerable sources.It is designed for researchers, clinicians, and students, providing an unparalleled depth of knowledge and insights into the diagnosis and treatment of abdominal pain. Expert contributors, selected for their specialized knowledge, bring the latest publications, advances, and cutting-edge research to ensure the most current information available. This innovative approach compiles diverse aspects of abdominal pain, offering insights into pathophysiology, molecular pathways, and potential cross-talks. Whether you are a seasoned clinician, a researcher, or a medical student, this guide will provide you with the most current and comprehensive information available, helping you stay at the forefront of abdominal pain diagnosis and treatment.
  • Nanotechnology in the Treatment of Infertility

    Practical Applications and Future Insights
    • 1st Edition
    • June 1, 2026
    • Pankaj Sharma
    • English
    Nanotechnology in the Treatment of Infertility: Practical Applications and Future Insights delves into the area where nanotechnology meets reproductive health care and reveals how the latest nanoscale developments are changing how infertility is treated. It examines current developments, principles, and possibilities of nanotechnology, with an emphasis on nanoparticle delivery systems, bioengineering, and their relevance in Assisted Reproductive Technologies (ART). This edited volume, written by leading scholars, provides a comprehensive overview of nanotechnology in relation to fertility. It will be of great interest to researchers, healthcare professionals, and anyone who wants to know more about this exciting area of potential solutions for infertility.
  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 134
    • June 1, 2026
    • English
    Advances in Applied Microbiology, Volume 134 presents a comprehensive exploration of the latest innovations in applied microbiology. The book delves into the diverse applications of microbiology across various industries, including agriculture, food production, biotechnology, environmental science, and healthcare. Through a collection of insightful chapters authored by experts in the field, readers are offered in-depth analyses of cutting-edge research, emerging trends, and practical applications of microbiological principles.From novel microbial technologies to the impact of microbiomes on human health and beyond, this book serves as a valuable resource for researchers, professionals, and students seeking to stay informed and inspired by the exciting advancements.
  • Mucosal Barriers and Host-Microbiota Interplay

    Dysbiosis to Barrier Dysfunction
    • 1st Edition
    • June 1, 2026
    • Linda Chia-Hui Yu
    • English
    Mucosal Barriers and Host-Microbiota Interplay: Dysbiosis to Barrier Dysfunction, a volume in Elsevier's new series Hot Topics in Physiology, provides an in-depth exploration of mucosal barriers, including their structure, establishment, and consideration of different diseases and intervention strategies. Published in association with the International Union of Physiological Sciences (IUSP), this is an ideal reference for those researching or studying biology and medicine, particularly gastroenterology. Biotechnological companies working on metagenomics sequencing and analysis may also find this volume useful.As a massive load of commensal microbes, consisting of bacteria, viruses, and fungi resides in the gastrointestinal tract and other mucosal surfaces, collectively termed microbiota, this book provides an update on new and existing knowledge. Mucosal barriers, including the epithelial layers and immune cells act as the frontline to strategically confine these microorganisms and prevent the entry of microbes into the body proper.
  • Cytokine-Based immunotherapy Part B

    • 1st Edition
    • Volume 401
    • June 1, 2026
    • English
    Cytokine-Based immunotherapy: Part B, Volume 401 delves into the intricate world of cytokines, vital signaling proteins that orchestrate the immune response and their pivotal role in modulating various immune functions. From their fundamental mechanisms to their therapeutic applications, this book offers a thorough examination of the latest trends and developments in leveraging cytokines for immunotherapy. Chapters cover Cytokine-based immunotherapy in pancreatic cancer, IL-33 and its pleiotropic role in cancer, Immunocytokines based on IL-12 for cancer therapy: enhancing efficacy and reducing toxicity, Cytokine network in immunosuppression and tumor development in glioblastoma, The Double-Edged Role of Interferon Gamma in Cancer Immunity, and much more.An additional section covers Engineering Interleukin-10 for Therapeutic Applications, IL-23 Blockade: A Strategy for Relieving Inflammatory Diseases. Targeting TNF-alpha examines the immunotherapeutic approach for alleviating neuropathic pain. The key role of immunomodulatory cytokines for the development of novel nk cell-based cancer therapies focuses on the importance of cytokines in developing new cancer treatments. Finally, complexities in the clinical development of TGFβ inhibitors covers the challenges in creating inhibitors for TGFβ.
  • Probiogenomics and Probiomics

    Concepts, Techniques, Applications, and Achievements
    • 1st Edition
    • June 1, 2026
    • Debmalya Barh + 1 more
    • English
    Probiogenomics and Probiomics: Concepts, Techniques, Applications, and Achievements is a pioneering reference book that marks a significant milestone in the emerging fields of probiogenomics and probiomics. As the first comprehensive resource in these disciplines, the book offers a detailed exploration of how genetic insights and omics technologies are revolutionizing our understanding of probiotics and their application in health and disease. Spanning three detailed sections, the book begins by grounding readers in the fundamental concepts of probiotics, including their roles in health enhancement and disease prevention. It progresses into a deep dive into advanced genomic and post-genomic technologies, revealing how these tools are used to dissect and harness the health-promoting capacities of probiotics. From the structure and function of probiotic genomes to the cutting-edge applications in synthetic biology and multi-omics, the book encapsulates the latest advancements and methodologies in the field. The final sections focus on the practical and clinical applications of these microbial marvels, discussing their impact on healthcare, biotechnology, and therapeutics. Whether it's developing new biotechnological products or enhancing therapeutic efficacy, this book covers a broad spectrum of applications, making it an invaluable resource for undergraduate and postgraduate students, researchers, clinicians, and industry professionals involved in drug and probiotics development. With contributions from over ten global experts, "Probiogenomics and Probiomics" not only educates but also inspires, providing a thorough understanding of modern probiogenomics and its potential to shape the future of personalized medicine and healthcare.