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Elsevier

Academic Press

  • Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

    • 1st Edition
    • Lara Scheherazade Milane + 1 more
    • English
    Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered.Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.

  • Membrane Transporters and Drug Delivery

    A Comprehensive and Multidisciplinary Guide
    • 1st Edition
    • Elena Puris + 3 more
    • English
    Membrane Transporters and Drug Delivery: A comprehensive and multidisciplinary guide begins with a comprehensive introduction to membrane transporters, their function, structure, and regulation mechanisms. It then moves into the impact of diseases on transporters and how this may affect pharmacokinetics. The book also presents the latest advancements in transporter-mediated drug delivery. A unique feature of this book is its detailed exploration of the methodologies used in transporter research, providing readers with a comprehensive understanding of the strengths and limitations of each approach. It examines the roles of both efflux and influx transporters in drug pharmacokinetics and covers different strategies for utilizing membrane transporters for drug delivery and targeting to specific tissues and cell types. The book concludes with a discussion on regulatory and industrial aspects of transporter-related projects and explores the potential of artificial intelligence in transporter and drug delivery research.Membrane Transporters and Drug Delivery: A comprehensive and multidisciplinary guide begins with a comprehensive introduction to membrane transporters, their function, structure, and regulation mechanisms. It then moves into the impact of diseases on transporters and how this may affect pharmacokinetics. The book also presents the latest advancements in transporter-mediated drug delivery. A unique feature of this book is its detailed exploration of the methodologies used in transporter research, providing readers with a comprehensive understanding of the strengths and limitations of each approach. It examines the roles of both efflux and influx transporters in drug pharmacokinetics and covers different strategies for utilizing membrane transporters for drug delivery and targeting to specific tissues and cell types. The book concludes with a discussion on regulatory and industrial aspects of transporter-related projects and explores the potential of artificial intelligence in transporter and drug delivery research.

  • Robotics for Intervention in Healthcare

    From Technology to Clinical Practice
    • 1st Edition
    • Françoise J Siepel
    • English
    Robotics for Intervention in Healthcare: From Technology to Clinical Practice bridges the gap between deep-core robotic intervention technology and clinical aspects, including content that is appropriate for physicians and clinicians. The book gives insights on the importance of connectivity in early stages, thoroughly addressing which aspects are important to improve the innovation chain.

  • Thermal System Design and Simulation

    • 2nd Edition
    • P.L. Dhar + 1 more
    • English
    Thermal System Design and Simulation, Second Edition covers the fundamental analyses of thermal energy systems that enable users to effectively formulate their own simulation and optimal design procedures. It provides step-by-step guidance on how to mathematically formulate objective functions and design constraints and develop strategies to solve them to obtain optimal solutions with minimal computational effort. It uniquely illustrates the methodology of combining information flow diagrams to simplify system simulation procedures needed in optimal design. Expanded and updated for currency, the book includes case studies and a comprehensive presentation on the dynamics of thermal systems and control systems needed to ensure safe operations.Designed to give readers the hands-on skills needed to develop their own customized software for simulating and designing thermal systems, this book is useful for anyone interested in obtaining advanced knowledge of thermal system analysis and design.

  • Vegan Food Products

    Sources, Production Methods, Challenges and Improvement Strategies
    • 1st Edition
    • Tuba Esatbeyoglu + 1 more
    • English
    Vegan Food Products: Sources, Production Methods, Challenges and Improvement Strategies assembles the science related to different vegan foods in a comprehensive reference that discusses the benefits and challenges of vegan food products. Comprised of 11 chapters, the book covers the vegan alternatives of different food groups, including meat, fish, egg, and dairy. It also presents a variety of vegan protein sources, such as plant-based proteins, macro- and microalgae and single-cell proteins. Sections explore production methods and technologies, including extrusion, dry-fractionation methods for enriching proteins, 3D printing, and in vitro methods. In addition, the health aspects of vegan foods, with a specific chapter devoted to the fortification studies, are covered, as well as the vegan food market, the consumer perception, and the sensory and nutritional quality of vegan products. Edited by well-known global researchers in the field, this book provides readers with a broad review of the most recent research on the opportunities and challenges of vegan ingredients and foods.

  • Acute Myocardial Infarction in Young Women

    Understanding its Mechanisms and Management
    • 1st Edition
    • Stéphane Peggy Manzo-Silberman
    • English
    Acute Myocardial Infarction in Young Women: Understanding its Mechanisms and Management serves as a seminal reference for understanding the current landscape of cardiovascular health in young women, highlighting clinical areas that require focused attention. By customizing the information to their unique physiological and clinical differences, more precise and effective interventions will lead to improved outcomes. The information is meticulously updated to address the specific cardiovascular health issues encountered by young women with myocardial infarction. This ensures that each stage of care—from cardiovascular risk assessment and symptom-recognition to the acute myocardial infarction (AMI) pathway, and rehabilitation follow-up—is optimized.Ultimately... this book equips health professionals with the most current and evidence-based information, enabling them to deliver the highest standard of care for young women with myocardial infarction. It will enhance quality of care, and contribute to improved health outcomes for young women across all stages of the cardiovascular healthcare continuum.

  • Starch Blends and Their Applications

    Sustainable Packaging Solutions
    • 1st Edition
    • Rafael Audino Zambelli
    • English
    Starch Blends and Their Applications: Sustainable Packaging Solutions, a new volume in the Applications of Starches in Food and Packaging series, discusses the latest advancements in production techniques and modification strategies for enhancing the functionality and compatibility of starch blends in multicomponent systems. The book presents case studies and real-world applications of starch blends in food processing, biodegradable materials, biomedical applications, and more, showcasing their diverse functionalities and potential benefits. Chapters also address challenges, opportunities, and future trends in starch blends research and development, offering insights into emerging technologies and areas for further exploration.Written by leading experts in the field, this book equips its audience with the knowledge, skills, and insights needed to navigate the complexities of starch blends and harness their potential in diverse applications.

  • Sustainable Supply Chain Management

    Computational Approaches and Modelling
    • 1st Edition
    • Syed Mithun Ali + 3 more
    • English
    Sustainable Supply Chain Management: Computational Approaches and Modelling provides a comprehensive understanding of how computational approaches can be leveraged to address the challenges associated with sustainable supply chain management. It offers insights into emerging and advanced modelling techniques to optimize supply chain operations while considering environmental, social, and economic factors. This book will be a valuable resource for researchers, practitioners, and policymakers interested in understanding and implementing sustainable supply chain management practices through computational approaches and modelling. This book helps researchers understand the opportunities, challenges, and solutions by developing innovative computational tools and techniques to integrate sustainability considerations into supply chain decision-making processes.

  • Anti-Obesity Drug Development

    Physiology, Pharmacology and Drug Delivery
    • 1st Edition
    • Fadia Salah Youssef + 1 more
    • English
    Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery is a complete reference for pharmaceutical researchers in this key area of research and clinical development. The contents of the book are organized in four parts. The first provides an overview of the foundations and historical development of anti-obesity drugs, including extensive discussion of comorbidities and how they impact drug activity and efficacy. Part two is dedicated to the drug targets involved in the progression of obesity treatment. These include GLPRI and GIPR agonists, Incretin/Glucagon, RM-493 and Liraglutide, Pramlintide and metreleptin, Growth Hormone, FXR and GPR131, and the Gut Microbiota. Part three discusses the most common drugs available in the market and their pharmacological parameters. The final part of the book covers all natural products known to have scientific evidence on the treatment of obesity.Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery is the perfect reference for pharmacology researchers and those involved in new drug development both in academic and corporate environments. Research-physicians, endocrinologists, and nutritionists will also benefit from the comprehensive overview of treatments covered in this book.

  • Pediatric Substance Exposure

    • 1st Edition
    • Ju Lee Oei
    • English
    Pediatric Substance Exposure is a crucial resource for medical practitioners focusing on the long-term management of children exposed to addictive substances during pregnancy. It provides guidance on supporting families affected by substance abuse, starting with a comprehensive overview of epidemiology and global policy. The book examines various substances and their impact on children, discussing fetal management, infant and child care, and addressing family needs as the child grows. Beyond the basics, the book reviews social aspects, future research, and policy needs. Clinicians and researchers will find it invaluable for evidence-based decision-making and optimal treatment strategies.

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