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Elsevier

Academic Press

  • Handbook of Proteolytic Enzymes

    Serine and Threonine Peptidases
    • 4th Edition
    • Neil D. Rawlings
    • English
    The Handbook of Proteolytic Enzymes, Fourth Edition is the latest release in this esteemed publication that stands as the most comprehensive work in applied enzymology and biocatalysis since the first edition published in 1998. Extensively updated, the new edition is an essential reference for biochemists, biotechnologists, and molecular biologists across academia and industry. Edited by world-renowned experts in the field, and with five volumes available for individual sale, this work provides detailed information on all known proteolytic enzymes researched to-date, with expanded coverage of metallopeptidases, cysteine peptidases, serine and threonine peptidases, aspartic and glutamic peptidases, and inhibitors of proteolytic enzymes.This volume includes over 400 chapters on known serine and threonine peptidases, including their name, history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing features, with 2D and 3D structures of peptidases in color, extensive references, and links to PubMed and MEROPS databases.

  • Handbook of Proteolytic Enzymes

    Cysteine Peptidases
    • 4th Edition
    • Neil D. Rawlings
    • English
    Handbook of Proteolytic Enzymes: Cysteine Peptidases, Fourth Edition is an essential reference for biochemists, biotechnologists, and molecular biologists across academia and industry. It includes over 300 chapters on known cysteine peptidases, including their name, history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing features, with color 2D and 3D structures of peptidases, extensive references, and links to PubMed and MEROPS databases.Edited by world-renowned experts in the field, and with five volumes available for individual sale, this work provides detailed information on all known proteolytic enzymes researched to-date, with expanded coverage of metallopeptidases, cysteine peptidases, serine and threonine peptidases, aspartic and glutamic peptidases, and inhibitors of proteolytic enzymes.

  • Clinician’s Guide to Headache

    Head, Neck, and Face Pain Syndromes
    • 1st Edition
    • Pravin Thomas
    • English
    Clinician’s Guide to Headache: Head, Neck and Face Pain Syndromes is a comprehensive reference that covers what headache specialists encounter in day-to-day headache practice settings. This practical volume is relevant as a primary reference for neurologists and other headache specialists looking for a resource on complex, acute headache management. Developments in the field are highlighted, including biologics and invasive and non-invasive neuromodulation. Chapters focus on anatomy and pathophysiology, neuroradiology, acute and chronic headaches, and clinically relevant sections on diagnosis and biases, consultation settings, placebos and nocebos, as well as the set-up of a comprehensive headache center.With a foundation based on recent developments in pathophysiology and anatomy, this volume provides an overview of headache disorders with a case-based approach.

  • Plant Polyphenols in the Food and Cosmetic Industries

    Extraction and Applications
    • 1st Edition
    • José Manuel Lorenzo
    • English
    Plant Polyphenols in the Food and Cosmetic Industries: Extraction and Applications explores the use of polyphenols in food and cosmetics. Broken into three parts, the book begins with coverage of extraction and purification processes before delving into specific food and cosmetic applications. Plant Polyphenols in the Food and Cosmetic Industries: Extraction and Applications provides nutrition researchers, food scientists, and plant scientists an opportunity to better understand the use of polyphenols in their industries.

  • Progress in Motor Control

    Crossroads between Neurophysiology and Applications
    • 1st Edition
    • Mark L. Latash + 4 more
    • English
    "Progress in Motor Control: Crossroads between Neurophysiology and Applications" offers an in-depth look at the evolving field of motor control, synthesizing the latest research. This volume explores the complex roles of the central nervous system in movement, featuring contributions from leading experts who use approaches ranging from basic physical principles to advanced control theory. It addresses applied aspects of motor control, focusing on recovery strategies for functional movements in patients with spinal cord injuries, subcortical disorders, and strokes. Organized into five sections, the book covers theoretical advances, neurophysiological mechanisms, motor learning, neural plasticity, and motor disorders, including topics like neural population dynamics and vestibulospinal reflexes. The final sections highlight strategies for improving recovery after neurological events. This resource bridges foundational research and clinical application, making it invaluable for researchers, clinicians, and students in motor control, neuroscience and rehabilitation.Divid... into five comprehensive parts, the book covers theoretical advances, neurophysiological mechanisms, motor learning, neural plasticity, and motor disorders, including essential topics like neural population dynamics and the dual role of vestibulospinal reflexes. Final sections highlight practical strategies for improving recovery outcomes following neurological events.

  • Mitochondrial Intoxication

    • 2nd Edition
    • Marcos Roberto de Oliveira
    • English
    Mitochondrial Intoxication, Second Edition offers a comprehensive and fully updated exploration of the impact of toxic molecules on mitochondrial physiology, and the diseases that result from their dysfunction. Divided into three sections, the book opens with a detailed overview of mitochondrial physiology, molecular markers of mitochondrial intoxication and challenges of mitochondrial profiling during pre-clinical studies. It then focuses on endogenous toxicants and their impact on mitochondria, including new chapters on lipids, glucose and microbiota-derived toxicants. Amyloid-β peptide and its impact on mitochondrial dysfunction is also a new addition to this book, as well as inflammation-induced mitochondrial intoxication. The final section explores exogenous toxicants, such as pollutants, food additives, illicit and pharmaceutical drugs, pesticides and heavy metals. The effects of micro- and nanoplastics on mitochondrial function are newly covered. Furthermore, the latest computational tools in mitochondrial toxicity research are investigated. Incorporating the latest advances in the field, “Mitochondrial Intoxication, Second Edition” offers cutting-edge insights on mitochondrial toxicity, and serves as an invaluable resource for researchers and advanced students in cell biology, molecular biology, toxicology, biochemistry, pharmacology, and related fields.

  • Neural Networks

    • 1st Edition
    • Volume 55
    • English
    Neural Networks, Volume 55 delves into the world of deep learning machines, defining neural networks and covering their central role in the development of modern language models, machine‑learning‑bas... decision‑making systems, and many other advances in artificial intelligence. Chapters in this new release include Neural networks with random weights, Bayesian Neural Networks for Official Statistics: Modeling High-Dimensional Structure in Complex Surveys and Administrative Records, Weakly supervised learning for neural networks, How to test a neural network as a null hypothesis, Test-Time Adaptation with Neural Networks: Approaches and Advances in Image Classification, and much more.Additional sections cover Semantics and Verification of Neural Network Components in Robotic Control Software, Artificial Neural Network Procedures for the Nonlinear Dynamical Plankton System, Neural Networks from Statistical Perspective, Neural Network applications in Assistive and Collaborative Robotics, Neural Network applications in Assistive and Collaborative Robotics, and Neural Networks using SPDEs.

  • Biomaterials in Cancer Therapy

    Innovations and Applications
    • 1st Edition
    • Alok Raghav
    • English
    Biomaterials in Cancer Therapy: Innovations and Applications explores the critical role of functional biomaterials in addressing one of today’s most pressing health challenges—cancer. Despite advancements in therapies, cancer continues to claim millions of lives annually, necessitating innovative approaches that integrate engineering and pharmaceutical sciences. This book highlights the potential of engineered biomaterials to enhance drug delivery, minimize side effects, and promote tissue regeneration, ultimately improving patient outcomes. The content examines cutting-edge innovations in functional biomaterials, including their applications in targeted drug delivery and immunotherapy, while emphasizing the role of nanotechnology in developing effective cancer theranostics with minimal toxicity. Targeted at academicians, physicians, and industry professionals, this book serves as a vital resource for understanding the transformative potential of functional biomaterials in oncology. By addressing real-world challenges and incorporating diverse perspectives, it inspires innovative solutions that enhance global healthcare outcomes for cancer patients.

  • Gallin and Ognibene's Principles and Practice of Clinical Research

    • 5th Edition
    • John I. Gallin + 2 more
    • English
    Gallin and Ognibene’s Principles and Practice of Clinical Research, Fifth Edition provides the definitive text on clinical research as written by internationally recognized experts from the National Institutes of Health, the US Food and Drug Administration, academia, and global researchers. This new edition contains more than 30 new authors and 9 new chapters. Topics covered emphasize the role of informatics in clinical research, incorporating clinical outcome assessment into endpoints for decision-making, inclusion of diverse and vulnerable research subjects, patient advocacy groups, rare disease research, preparing research for pandemics, public health emergencies, research opportunities for surgeons, and content on preclinical animal studies.For the international researcher, two new chapters detail international clinical research experiences in South Africa, India, and Pakistan. As with the previous edition, the new release provides readers with summary questions and answers after each chapter.

  • Pharmacological Foundations of Parkinson’s Disease

    From Mechanisms to Clinical Practice
    • 1st Edition
    • Wael Mohamed
    • English
    Pharmacotherapy of Parkinson's Disease: from Basics to Practice provides a comprehensive guide on the pharmacological treatment of Parkinson's Disease, offering students and clinicians a combination of foundational knowledge and advanced clinical insights. The book bridges theoretical concepts with real-world clinical scenarios and equips readers with the tools necessary to effectively manage Parkinson's Disease in practice. Offering a detailed review of symptoms, treatment gaps, and emerging therapies, this book delves into the pathogenesis the disease, along with dopaminergic treatments and management of motor and non-motor symptoms.Providing updates on emerging therapies, including innovative treatment approaches, this book serves as a valuable reference for continuous learning and staying current with evolving practices and research in Parkinson's Disease management.

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