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Academic Press

  • Capsaicin, the Pungent Principle in Hot Pepper

    From Basic Pharmacology to Therapeutic Applications
    • 1st Edition
    • Arpad Szallasi
    • English
    Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications explores capsaicin's biological and pharmacological characteristics, from its discovery and isolation to its receptor identification and antagonists. The book's structure is divided into three sections, starting with the historical development of research on capsaicin. This foundational section provides a thorough understanding of the compound's journey from a simple pungent ingredient to a significant element in pharmacological studies. The second part of the book delves into capsaicin’s biological effects and pharmacology, covering areas such as nociception, pain, salivary secretion, body temperature regulation, and blood pressure regulation.Finally, the book examines the clinical applications of capsaicin, discussing potential future developments in desensitization, pain relief, injections, effects on the tumor microenvironment, appetite control, and longevity. This book is invaluable for pharmacology researchers and clinicians in pain management and cancer, offering insights into the unique characteristics and therapeutic potential of capsaicin.

  • The Neuroscience of Deep Brain Stimulation

    Research and Clinical Applications
    • 1st Edition
    • Yasin Temel + 2 more
    • English
    Neuroscience of Deep Brain Stimulation: Research and Clinical Applications begins by introducing readers to the foundational research and historical background of DBS, including developmental experimental models for movement and psychiatric disorders. The second section reviews various clinical applications, including numerous and in-depth case studies. The final section identifies the mechanisms of action behind DBS, including cellular, metabolic, and neurochemical mechanisms. Internationally contributed, this book is an essential guide for anyone in the field of DBS.

  • Fundamentals of Translational Tissue Engineering

    • 1st Edition
    • Yogesh Kumar Verma + 3 more
    • English
    Fundamentals of Translational Tissue Engineering explores the practical dimensions of tissue engineering (TE), outlining the intricate path of development of tissue engineered products. The book navigates the reader through the fundamental aspects and challenges in TE, equipping the reader with insights crucial to comprehending the journey a tissue engineered product traverses on its way to clinical translation. The first section, Material Sciences, provides the reader with a general overview covering the basics of scaffolds, biomaterials and techniques, while the larger, second section, Biological and Clinical Aspects, discussing the biological perspectives relating to tissue engineering.This is a multi-disciplinary work that will be ideal for audiences of varying levels of expertise, from the novice exploring fundamental concepts or the seasoned professionals seeking comprehensive information, readers of all backgrounds will be able to access and benefit from this tailored approach.

  • Advances in Virus Research

    • 1st Edition
    • Volume 124
    • English
    Advances in Virus Research, Volume 124 in this ongoing seriesseries, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Emerging and Reemerging Viral Threats to Pregnancy and Nomenclature for vertically transmitted plant.

  • Artificial Intelligence for Multi-omics Analysis Part A

    • 1st Edition
    • Volume 221
    • English
    Artificial Intelligence for Multi-omics Analysis, Part A, Volume 221 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as an Introduction to Artificial Intelligence in Multi-omics Analysis, Multi‐omics application in health and diseases, Artificial Intelligence in Genomics Analysis, Artificial Intelligence in Single-cell and Spatial Transcriptomics Data, Artificial Intelligence in the prediction of 3D chromatin structure and gene regulation, Artificial intelligence in Mass Spectrometry-based Proteomics, Integrating Artificial Intelligence into Metabolomics for Predicting Diseases, and more.Additional chapters cover Artificial Intelligence in Microbial Metagenomics, Artificial Intelligence in Interactomics, Artificial Intelligence Integration in Medical Imaging Data, AI in biomolecular structural data analysis, Artificial intelligence in Cryo-Electron Microscope data, Explainable artificial intelligence for multi-omics data, and Multi-Omics Cancer Stratification: from Statistical to Deep Learning Perspective.

  • Growth Hormone and Related Disorders: From Clinics to Diagnosis

    • 1st Edition
    • Volume 131
    • English
    Growth Hormone and Related Disorders: From Clinics to Diagnosis, Volume 131 covers various topics related to growth hormone and its associated disorders when there is a GH excess, including their pathophysiology, clinical presentation and diagnosis. Chapters in this new release include Growth hormone: synthesis and regulation, GH and GnRH-gonadotropin secretion, Co-Secreting Pituitary Adenomas in Acromegaly: Classification, Diagnosis, and Treatment Strategies, Growth hormone and glycemic metabolism, Acromegaly: pathophysiology and etiology, Acromegaly: biochemical diagnosis, Acromegaly and clinical manifestations, and more.Additional sections discuss Gigantism, Acromegaly and genetics, Molecular markers of response to medical therapy in acromegaly, and Acromegaly and histopathology.

  • Sensory Approaches to Mental Health Practice

    • 1st Edition
    • Tawanda Machingura + 1 more
    • English
    Sensory Approaches to Mental Health Practice explores the latest research on various targeted sensory programs, including case studies for clinical applications. Offering different sections on theory and structured frameworks, it covers various topics such as the polyvagal theory, occupational behavior theory, and trauma informed care, both in research and in clinical applications. This book provides readers with the knowledge, skills, and tools based on sensory approaches that will be effective to use with their clients in various situations and settings.

  • Emotional Security and Conflict in Context

    A Developmental Psychopathology Perspective on Youth Adjustment
    • 1st Edition
    • E. Mark Cummings + 1 more
    • English
    Emotional Security and Conflict in Context: A Developmental Psychopathology Perspective on Youth Adjustment covers the effects of conflict on children. Moving beyond conflict in the family, over 1 billion children are affected by community and political conflict and war, which also has profound and long-lasting implications for development. This book integrates several theoretical models that are central to work in this field, providing a clear review of the literature in a way that systematically and logically flows. In addition, it discusses child development from a developmental psychopathology perspective.Finally, the book integrates perspectives on violence and conflict across the social ecology, as well as several theoretical frameworks that are core to the field.

  • The Story of GLP-1

    A Historical Journey in the Treatment of Diabetes and Obesity
    • 1st Edition
    • Jens Juul Holst
    • English
    The Story of GLP-1: A Historical Journey in the Treatment of Diabetes and Obesity offers a compelling narrative about the discovery and development of the hormone GLP-1, which has revolutionized modern approaches to diabetes and obesity. Award-winning scientist Professor Jens Juul Holst, alongside co-authors Professor Sten Madsbad, Professor Jens Meldgaard Bruun, and Novo Nordisk Foundation CEO Mads Krogsgaard Thomsen, trace the scientific breakthroughs and clinical advances that have made GLP-1 therapies, such as Ozempic and Wegovy, essential tools for improving blood sugar control and promoting meaningful, lasting weight loss in patients worldwide.The book explores the rising global prevalence of obesity and diabetes, emphasizing the urgent need for innovative solutions. It critically examines traditional treatments, noting their limitations in sustaining weight loss or reducing complications. The narrative details the paradigm shift brought by GLP-1 medications, including liraglutide and semaglutide, which offer improved cardiovascular outcomes and significant health benefits. The authors also address ongoing challenges of accessibility and affordability, prompting important societal discussions about equitable distribution and funding for these lifechanging therapies.

  • Sustainable Development of Renewable Energy

    Volume 2: Opportunities in Production, Storage, and Integration
    • 1st Edition
    • Mejdi Jeguirim
    • English
    Sustainable Development of Renewable Energy: Volume 2—Opportunities in Production, Storage, and Integration is the sixth book in the Advances in Renewable Energy Technologies series. Based on the key themes of the International Renewable Energy Congress (IREC), this volume looks at the production performance of renewable energy sources and emerging production processes.Containing all major renewable energy technologies in individual chapters, this reference includes some of the most dynamic developments, good practices, and future concepts in solar energy systems, energy storage, geothermal energy, bioenergy, wind energy, fuel cell, and hydrogen production, as well as in policy and regulation. By reviewing these state-of-the-art advances, considering them with real work application, and analyzing key challenges, this book provides readers with an up-to-date source on renewable energy grid integration and its importance in aiding the energy transition.This is a valuable resource for graduates, researchers, professors, and industry professionals involved in the renewable energy sector, as well as advanced engineering courses dealing with renewable energy, sources, thermal and electrical energy production, and sustainability.

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