Cancer Biomarkers and Oncoviruses
- 1st Edition - December 10, 2025
- Latest edition
- Editor: Moulay Mustapha Ennaji
- Language: English
Cancer Biomarkers and Oncoviruses examines the extensive clinical applications of biomarkers in cancer research, with a particular focus on oncoviruses. The book explores key to… Read more
The present book also covers critical analyses of cost savings in healthcare, respiratory biomarkers in viral infections, and lessons learned from the COVID-19 pandemic, focusing on pandemic preparedness, early detection, surveillance, and response strategies. These discussions aim to provide valuable insights into how lessons from the pandemic can be applied to improve healthcare systems and response strategies for both viral infections and cancer, helping inform future health management practices.
This book is an invaluable resource for health professionals, scientists, researchers, health practitioners, students, and anyone seeking to deepen their understanding in the field of cancer and virology. It offers valuable state-of-the-art insights, incorporating the latest research and cutting-edge developments in the field.
- Provides current, systematic scientific information on oncoviruses, including the molecular characteristics of cancers associated with these viruses, along with recent diagnostic and treatment strategies, and future perspectives in the field
- Addresses key topics in tumor science by offering a comprehensive overview of cancers, covering diagnosis, cellular mechanisms, and therapeutic approaches
- Incorporates critical analyses and lessons learned from the COVID-19 pandemic, focusing on pandemic preparedness, early detection, surveillance, and response strategies, providing insights that can be applied to cancer research and healthcare management
- Offers up-to-date and comprehensive information to support informed decision-making regarding cancer diagnosis, treatment, and research, while also helping to shape future healthcare practices
Chapter 1: Breast cancer and new methods for treatment
Zineb Habdoudou, Ikram Tiabi and Moulay Mustapha Ennaji
Chapter 2: The role of genetic markers P53, BRCA1, and BRCA2 in breast cancer risk assessment in women
Rihabe Boussettine, Najwa Hassou, Mouad Najih, Imane Saif, Nadia Ghosne, Zakaria Albakardi, Redouane Ahnyne, Fatima Ezzahra Rihane, Hind Berradi and Moulay Mustapha Ennaji
Chapter 3: MicroRNAs as key regulators of hormone dependent pathways in breast cancer
Imane Guemih, Adila Noufel, Ikram Tiabi, Haytam Mahmoudy and Moulay Mustapha Ennaji
Part 2 Lung and prostate cancer: genetic abnormalities and biomarkers
Chapter 4: Genetic abnormalities of the EGFR pathway in the Middle East and North African patients with non-small cell lung cancer
Abdelilah Laraqui, Youssra Boustany, Idriss Lahlou Amine, Hicham Souhi, Hanane Elouazzani, Ismail Abderrahmani Rhorfi, Ahmed Abid, Moulay Mustapha Ennaji, Bouchra Belkadi and Khalid Ennibi
Chapter 5: MicroRNAs: advances in biomarkers, diagnostics, and therapeutic strategies in prostate cancer
Imane Mharrach, Kaoutar Anouar Tadlaoui, Mouna Aqerrout, Imane Ouariaghli and Moulay Mustapha Ennaji
Part 3 HPV and cervical cancer: screening, prevention, and molecular mechanisms
Chapter 6: Human papillomavirus infections in cervical cells for cervical cancer screening
Rihabe Boussettine, Hind Berradi, Najwa Hassou, Imane Saif, Mouad Najih, Zakaria Albakardi, Redouane Ahnyne, Nadia Ghosne and Moulay Mustapha Ennaji
Chapter 7: MicroRNA and human herpesvirus 8 oncovirus in prostate cancer
Adila Noufel, Imane Guemih, Ikram Tiabi and Moulay Mustapha Ennaji
Part 4 Vitamin D and immune modulation in cancer
Chapter 8: Prostate cancer antigen 3 as a diagnostic, prognostic, and therapeutic biomarker in prostate cancer
Imane Mharrach, Mouna Aqerrout, Kaoutar Anouar Tadlaoui, Imane Ouariaghli and Moulay Mustapha Ennaji
Chapter 9: Interaction of the vitamin D in cancer development and progression
Kawtar Nabil, Hasna Azmi, Zineb Sakhi, Ikram Tiabi and Moulay Mustapha Ennaji
Part 5 Emerging therapies and biomarkers in cancer
Chapter 10: Study of the role of microRNAs in epstein barr virus induced prostate carcinogenesis
Meryem Sadkaoui, Imane Saif, Mohammed Nabil Benchekroun and Moulay Mustapha Ennaji
Chapter 11: Addressing the burden of human papillomavirus-related cancers in North Africa: epidemiology, sociocultural barriers and prevention strategies
Youssef Ikken, Najwa Hassou, Redouane Ahnyne, Ikram Tiabi, Majdouline Obtel, Yassine Sekhsokh, Rachid Rahhal and Moulay Mustapha Ennaji
Part 6 Management of the COVID-19 pandemic: lessons learned, surveillance, and respiratory biomarkers in SARS-CoV-2 pathogenesis
Chapter 12: Management of the COVID-19 pandemic in Skhirate-Temara, Morocco: lessons in preparedness, surveillance, and rapid response
Youssef Ikken, Setti Naima Derfoufi, Ali Malki, Ilham Otmani, Noria Saidi, Najwa Hassou, Redouane Ahnyne, Yassine Sekhsokh, Majdouline Obtel, Bouchra Assarag, Souad El Hassani, Asmae Khattabi and Moulay Mustapha Ennaji
Chapter 13: Respiratory biomarkers in the pathogenesis of SARS-CoV-2
Med Salem Sid’Ahmed El Kehel, Rihabe Boussettine and Moulay Mustapha Ennaji
Part 7 Viral miRNAs and oncoviruses: diagnostic, prognostic biomarkers, and therapeutic implications in cancer
Chapter 14: Oncoviruses and cancer biomarkers: current and future perspectives
Ihsan Ali Mahasneh, Moulay Mustapha Ennaji and Berjas Abumsimir
Chapter 15: MicroRNAs in cancer development: biomarkers, functions and therapy
Nadia Takati, Ikram Tiabi, Hasna Azmi and Moulay Mustapha Ennaji
Chapter 16: Viral miRNA’s: unlocking new frontiers in virus-induced cancers
Mohamed Rida Znady, Abdelilah Laraqui, Idriss Lahlou Amine, Hicham Oumzil, Rachid Abbi, Moulay Mustapha Ennaji, Khalid Ennibi and Mohamed Rida Tagajdid
Part 8 Genetic and molecular basis of cancer
Chapter 17: Molecular alterations involved in lung cancer
Hind Berradi, Rihabe Boussettine, Nadia Ghosne, Moad Najih, Imane Saif, Najwa Hassou and Moulay Mustapha Ennaji
Chapter 18: Oncogenic BRAF in prostate cancer: exosomes and miRNA status and implications for targeted therapy
Ikram Tiabi, Nadia Takati, Hafida El Hichou Dbilen, Imane Saif, Kawtar Nabil, Fatima Ezzahra Rihane, Mohammed Nabil Benchekroun and Moulay Mustapha Ennaji
Chapter 19: Targeted therapy in prostate and bladder cancer—role of BRAF and RAS mutations
Ikram Tiabi, Nadia Takati, Imane Saif, Fatima Ezzahra Rihane, Kawtar Nabil, Zineb Sakhi, El Hichou Dbilen Hafida, Adila Noufel, Imane Guemih, Mohammed Nabil Ben Chekroun and Moulay Mustapha Ennaji
Chapter 20: In-depth analysis of tumor markers in leukemia
Najwa Hassou, Adila Noufel, Redouane Ahnyne, Rihabe Boussettine, Hind Berradi and Moulay Mustapha Ennaji
Part 9 Molecular mechanisms and therapeutic implications in cancer
Chapter 21: Nasopharyngeal cancer associated with epstein barr virus
Meryem Sadkaoui, Imane Saif, Mohammed Nabil Benchekroun and Moulay Mustapha Ennaji
Chapter 22: Molecular mechanisms of cervical cancer
Imane Guemih, Adila Noufel, Ikram Tiabi, Haytam Mahmoudy and Moulay Mustapha Ennaji
Part 10 Economic and market analysis in cancer research
Chapter 23: Critical analysis of the cost savings generated by biomarkers and oncoviruses in healthcare
Redouane Ahnyne, Yassire Abouabdilah, Najwa Hassou, Mohammed El Mzibri, Abdelilah Laraqui, Abdellatif Chakor and Moulay Mustapha Ennaji
Chapter 24: Market analysis of exosome technologies for the diagnosis of genitourinary cancers
Redouane Ahnyne, Najwa Hassou, Abdelouahid Ezzarfi, Rihabe Boussettine, Youssef Ikken, Abdelilah Laraqui, Abdellatif Chakor and Moulay Mustapha Ennaji
Part 11 Phage therapy and immune modulation
Chapter 25: Phagotherapy: The discreet power of our immune cells
Najoie Filali Ansari and Moulay Mustapha Ennaji
Part 12 Emerging therapies and biomarkers in cancer
Chapter 26: Mechanism of resistance to platinum salt-based chemotherapy
Hind Berradi, Rihabe Boussettine, Nadia Ghosne, Moad Najih, Imane Saif, Najwa Hassou and Moulay Mustapha Ennaji
Chapter 27: Marine algae as a source of bioactive compounds: unlocking anticancer potential
Hassou Najwa, Redouane Ahnyne, Ahnyne Redouane, Ezzarfi Abdelouahid, Hdija Badr, Errhif Ahmed and Moulay Mustapha Ennaji
Chapter 28: Cervical cancer: new treatment approaches using microRNA
Hafida El Hichou Dbilen, Ikram Tiabi and Moulay Mustapha Ennaji
Chapter 29: Therapeutic potential of the intratumoral microbiota in tumors
Haytam Mahmoudy, Imane Guemih and Moulay Mustapha Ennaji
Chapter 30: Molecular biomarkers in bladder cancer: identification and clinical relevance
Mouna Aqerrout, Imane Mharrach, Kaoutar Anouar Tadlaoui, Imane Ouariagli and Moulay Mustapha Ennaji
Chapter 31: Emerging biomarker applications for precision targeting in bladder cancer therapy
Mouna Aqerrout, Kaoutar Anouar Tadlaoui, Imane Mharrach, Imane Ouariaghli and Moulay Mustapha Ennaji
Chapter 32: Fusion gene and cancer
Kawtar Aboulaalaa, Youssef Ennaji, Imane Saif, Kawtar Nabil and Moulay Mustapha Ennaji
Chapter 33: Immunotherapy biomarkers in melanoma: fromprogrammed death-ligand 1 expression to tumor mutational burden
Nouhayla Moutanabi, Ikram Tiabi and Moulay Mustapha Ennaji
Chapter 34: The role of vitamin D supplementation in cancer treatment
Zineb Sakhi, Kawtar Nabil, Kaoutar Anouar Tadlaoui, Ikram Tiabi, Khaoula Elghazali and Moulay Mustapha Ennaji
Chapter 35: The role of vitamin D in modulating immune responses against oncoviruses human papillomavirus, Epstein–Barr virus, and human herpesvirus-8
Kawtar Nabil, Hasna Azmi, Zineb Sakhi, Kawtar Aboulalaa, Imane Saif, Ikram Tiabi and Moulay Mustapha Ennaji
Part 13 Epigenetics and DNA methylation in cancer
Chapter 36: Post-transcriptional epigenetic marks: DNA and microRNA methylation
Imane Saif, Rihabe Boussettine, Hind Berradi, Ikram Tiabi, Kawtar Nabil, Kawtar Tadlaoui, Youssef Ennaji, Kawtar Aboulaalaa and M.M. Ennaj
Chapter 37: Epigenetic mechanism induced by human herpesvirus 8 in prostate cancer
Adila Noufel, Imane Guemih, Ikram Tiabi and Moulay Mustapha Ennaji
Chapter 38: Role of methylation DNA in cell regulation
Imane Saif, Rihabe Boussettine, Hind Berradi, Youssef Ennaji, Ikram Tiabi, Kawtar Aboulaalaa and Moulay Mustapha Ennaji
Chapter 39: DNA methylation biomarkers in colorectal cancer
Meryem Jafari, Boutaina Addoum, Imane Chaoui, Laila Benbacer, Walid Baba, Mohammed Oukabli, Abdelmounim Ait Ali, Noureddine Njoumi, Sidi Mohammed Bouchantouf, Ahmed Bounaim, Amina Ennya, Khalid Ennibi, Youssef Bakri, Moulay Mustapha Ennaji, Mohamed El Mzibr, Abdelilah Laraqui and Mohammed Attaleb
Part 14 Oncoviruses and viral-associated cancers
Chapter 40: Deciphering the molecular tapestry: extracellular vesicles as pioneering biomarker reservoirs for precision therapy in urogenital cancers
Khaoula Elghazali, Youssef Ennaji, Zineb Sakhi, Ikram Tiabi and Moulay Mustapha Ennaji
Chapter 41: Retroviruses as biomarkers in prostate carcinoma
Imane Ouariaghli, Soukayna Alaoui Sosse, Mouna Aqerrout, Imane Mharrach, Abdelilah Laraqui, Mohammed Mrabti, Mohamed Alami and Moulay Mustapha Ennaji
Chapter 42: The role of breast cancer gene 1 and breast cancer gene 2 in determining breast cancer therapy
Soukayna Alaoui Sosse and Moulay Mustapha Ennaji
Chapter 43: The biomarkers landscape in lung cancer: implication for diagnosis, prediction, and prognosis
Fatima Zohra Attouahri, Abdelilah Laraqui, Imane Chaoui, Mohamed Rida Tagajdid, Laila Benbacer, Boutaina Addoum, Khaoula Errafii, Mouna Ababou, Mohammed Attaleb, Khalid Ennibi, Moulay Mustapha Ennaji and Mohammed El Mzibri
Chapter 44: Human papillomavirus as the main cause of cervical cancer: diagnosis, treatment, and prevention
Hassou Najwa, Rihabe Boussettine, Noufel Adial, Rahhal Rachid, Redouane Ahnyne, Baradi Hind and Moulay Mustapha Ennaji
Chapter 45: Oncogenic role of proline-rich protein 11 in breast and gynecologic cancers: mechanisms, signaling pathways, and therapeutic implications
Kaoutar Anouar Tadlaoui and Moulay Mustapha Ennaji
Chapter 46: MicroRNAs as biomarkers in gynecological-mammary cancers
Kaoutar Anouar Tadlaoui, Mouna Aqerrout, Imane Mharrach and Moulay Mustapha Ennaji
Chapter 47: Proline-rich protein 11 as a diagnosis and prognosis biomarker in breast and cervical cancers
Kaoutar Anouar Tadlaoui, Mouna Aqerrout, Imane Mharrach, Zineb Sakhi and Moulay Mustapha Ennaji
Chapter 48: Recent advances in therapy and biomarkers: triple negative breast cancer
Imane Guemih, Adila Noufel, Maryame Lamsisi, Haytam Mahmoudy and Moulay Mustapha Ennaji
Chapter 49: Recent advances in exosome-based therapies for prostate cancer: targeting oncoviral and epigenetic pathways
Adila Noufel, Imane Guemih and Moulay Mustapha Ennaji
Chapter 50: Exosomes as carriers of viral and host biomarkers in virus-associated gynecological cancers
Adila Noufel, Imane Guemih, Maryame Lamsisi, Maxim V. Berezovski and Moulay Mustapha Ennaji
- Edition: 1
- Latest edition
- Published: December 10, 2025
- Language: English
ME
Moulay Mustapha Ennaji
Dr. Moulay Mustapha Ennaji, Professor in Virology and Oncology at the University of Casablanca and Director of the Quality and Medical Biotechnologies Team at Laboratory of Virology Microbiology, Hassan II University Mohammedia of Casablanca, Morocco He is currently a Professor in Virology and Oncology at the University of Casablanca, and since 2010, he has been the Director of the Quality and Medical Biotechnologies Team at the Laboratory of Virology Microbiology, Quality, Biotechnologies. He received a MSc in 1986 and a PhD in virology in 1993 from Armand Frappier Institute, University of Quebec (Canada). He has published dozens of journals articles and is an editorial board member of the journal, Infectious Agents and Cancer. Throughout his career, Dr. Ennaji has been rewarded several awards. At present, he is the vice president of the three Moroccan societies of Biosafety, Cancer, and Microbiology.