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Elsevier

Diagnostic Application of Blood-based Biomarkers for Neurodegenerative Diseases

  • 1st Edition - November 18, 2026
  • Latest edition
  • Editors: Meenakshi Dhanawat, Niraj Kumar Singh, Bharat Bhushan, Arun Kumar Singh, Garima Malik
  • Language: English

Diagnostic Application of Blood-based Biomarkers for Neurodegenerative Diseases is a comprehensive exploration of the pivotal role blood-based biomarkers play in diagnosing and ma… Read more

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Description

Diagnostic Application of Blood-based Biomarkers for Neurodegenerative Diseases is a comprehensive exploration of the pivotal role blood-based biomarkers play in diagnosing and managing neurological disorders. This comprehensive guide emphasizes the need for early detection and intervention in conditions such as Alzheimer’s disease, Parkinson’s disease, and neuroinflammation. Each chapter delves into specific biomarkers, including glial fibrillary acidic protein and neurofilaments, elucidating their diagnostic potential. This book highlights recent advancements in the application of blood biomarkers across various neurodegenerative diseases, underscoring the integration of artificial intelligence in biomarker discovery. By bridging research and clinical practice, it serves as an essential resource for professionals in diagnostic sciences, pharmaceutical research, and clinical pharmacology. Ultimately, this volume aims to reshape the landscape of early diagnosis, offering insights that promise to enhance personalized treatment strategies and improve patient outcomes in the fight against debilitating neurological disorders.

Key features

  • Explores the latest research on emerging blood-based biomarkers specific to various neurodegenerative diseases
  • Analyzes case studies showcasing successful implementations of blood biomarkers in clinical settings
  • Highlights the role of interdisciplinary collaboration in advancing biomarker research, emphasizing the importance of partnerships between neurology, biotechnology, and data science
  • Discusses the ethical considerations and regulatory challenges associated with the clinical use of blood-based biomarkers
  • Proposes future directions for research and clinical practice, identifying gaps in current knowledge and potential avenues for innovation in neurodegenerative disease diagnostics

Readership

Neurologists and healthcare professionals specializing in neurodegenerative diseases; Researchers and scientists in the fields of neurology, biomarker discovery, and biotechnology; Clinical pharmacologists and pharmaceutical researchers focused on neurological disorders; Medical students and residents interested in neurology and diagnostics

Table of contents

1. The Role of Biomarkers in Neurological Disorder

2. Understanding the Role of Serum Biomarkers in Neurological Disorders

3. Serum Glial Fibrillary Acidic Protein: Insights into Blood Biomarkers for Neurological Disorders

4. The Role of Neurofilaments as Biomarkers in Neurological Disease Diagnosis

5. Advances in Alzheimer’s Diagnosis: The Role of CSF and Blood Biomarkers

6. The Role of Alpha-Synuclein and other Blood Biomarkers in Parkinson’s Disease Progression

7. Advances in Huntington’s Disease Diagnostics: The Role of Blood Biomarkers

8. Unveiling Amyotrophic Lateral Sclerosis: The Role of Blood Biomarkers in Diagnosis and Management

9. Advances in Frontotemporal Dementia Diagnostics: The Emerging Role of Blood-Based Biomarkers

10. From Research to Reality: Translating Blood Biomarkers into Clinical Practice

11. Plasma biomarkers for neurodegenerative disorders

12. Fluid biomarkers for the diagnosis of neurodegenerative diseases

13. Advances in AI-based biomarker discovery for neurodegenerative diseases.

14. Blood Biomarkers in Neurodegenerative Diseases: Implications for the Clinical Trials

Product details

  • Edition: 1
  • Latest edition
  • Published: November 18, 2026
  • Language: English

About the editors

MD

Meenakshi Dhanawat

Dr. Meenakshi Dhanawat is an Associate Professor at the Amity Institute of Pharmacy, Amity University Haryana, with over 18 years of experience in Pharmaceutical Sciences and Medicinal Chemistry. She completed her Master's degree at NIPER, Mohali, focusing on glycosylamino acids, and earned her Ph.D. from IIT-BHU, Varanasi, investigating CNS drug delivery targeting 5HT1A/2A receptors. Her research encompasses synthetic and heterocyclic chemistry, nanotechnology, drug delivery systems, prodrug design, complexation, polymer chemistry, and herbal drug extraction. Dr. Dhanawat has received notable international recognition, including a travel grant from the AAPS Drug Delivery and Development section for the 2010 National Biotechnology Conference in California, and international travel grants from DBT and DST, Government of India, for conferences in California and Munich. Her distinguished honors include the Rajiv Gandhi National Fellowship, affirming her sustained contributions to pharmaceutical research and academic excellence.
Affiliations and expertise
Associate Professor, Amity Institute of Pharmacy, Amity University, Haryana, India

NS

Niraj Kumar Singh

Dr. Niraj Kumar Singh, current working as assistant professor at GLA University, Mthura UP has more than 10 years of research and teaching experiences in the field of pharmacy. He has published more than 20 articles in reputed international and national SCI peer reviewed journals having good impact factor. During my M Pharm work, he evaluated the natural pytochemicals as novel anti-asthmatic agents. During doctoral work he was basically involved in the neuropharmacology and explored the novel target and therapeutic strategy for the management of Alzheimer’s disease (AD). His research involves pharmacological evaluation of natural flavonoid as alternative pharamacophore for prevention and treatment of dementia especially AD. Further, he evaluated and explored the cellular and molecular mechanisms involved in the neuroprotective potential of natural flavonoid. His research work provides the new scope for the researchers and scientist further to establish and evaluate the efficacy and therapeutic potential of natural flavonoid for management, treatment and prevention neurodegenerative disorders like AD.

Affiliations and expertise
Assistant Professor, Institute of Pharmaceutical Research, GLA University, India

BB

Bharat Bhushan

Mr. Bhushan has a background in Pharmaceutical Sciences with a specialization in Pharmacology. He has done Masters from GLA University, Mathura and the project was based on Neurological disorders. Apart from that he is having experience in many pharmaceutical instruments and extraction of herbal drugs. His area of interest is Neurological Disorders, Natural compounds, molecular pathways and Drug Delivery.

He is currently working as Asst. Professor in Institute of Pharmaceutical Research, GLA University Uttar Pradesh. He has 2 years of teaching and research experience. He has attended several national and international conferences in India. He has done her M. Pharmacy project on the topic of “Pharmacological evaluation of silibinin against 3-NP induced Huntington’s disease in rodents”. He has more than 19 Publications in nations and international journal. His area of interest is role of Herbal constituents in brain related disorder.

Affiliations and expertise
Asst. Professor, Institute of Pharmaceutical Research GLA University, India

AS

Arun Kumar Singh

Arun Kumar Singh is an Assistant Professor in the Department of Pharmacy at University School of Pharmaceutical Sciences, Rayat Bahra University V.P.O. Sahauran, India. He completed his M.Pharm in Pharmaceutics from Galgotias University, Greater Noida. His research interests include nano-formulation, blockchain, IoT, machine learning, artificial intelligence, big data analytics, cancer biology, and neuroscience. He has contributed to academic books and book chapters and has published review articles in the areas of pharmaceutical sciences and healthcare technology. His work focuses on interdisciplinary approaches integrating pharmaceutical research with emerging digital and computational technologies.
Affiliations and expertise
Assistant Professor, University School of Pharmaceutical Sciences, Rayat Bahra University V.P.O. Sahauran, Tehsil Kharar, Distt. Mohali, Punjab, India

GM

Garima Malik

Garima Malik has completed her B. Pharmacy from Vaish Institute of Pharmaceutical Education and Research, Rohtak, and an M.Pharmacy from Chandigarh College of Pharmacy, Landran. She has more than 3 years of experience as an Assistant Professor in the Department of Pharmaceutics. Currently, she is working as an Assistant Professor at M.M College of Pharmacy, Maharishi Markandeshwar University, Mullana, Ambala, India. Ms Garima had about 1.5 years of experience as an officer in the Quality control department at Zenacts Pharma Manimajra, Chandigarh. Her M.Pharmacy project focused on the topic of “Preparation and evaluation of Fusidic acid loaded transferosomes amalgamated with gel for the management of burn wound infection”. She has published more than 10 publications, including 1 Patent, and 5 book chapters. Her area of interest is nanotechnology, hydrogels, biomaterials, and their application in drug delivery.
Affiliations and expertise
Chitkara college of pharmacy, Chitkara University Rajpura, Punjab, India