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Elsevier

Academic Press

  • Polymer-Drug Conjugates

    Linker Chemistry, Protocols and Applications
    • 1st Edition
    • Jitender Madan + 3 more
    • English
    Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of ‘Linker Chemistry’ in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding. The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits.

  • Introduction to Probability Models

    • 13th Edition
    • Sheldon M. Ross
    • English
    *Textbook and Academic Authors Association (TAA) McGuffey Longevity Award Winner, 2024*A trusted market leader for four decades, Sheldon Ross’s Introduction to Probability Models offers a comprehensive foundation of this key subject with applications across engineering, computer science, management science, the physical and social sciences and operations research. Through its hallmark exercises and real examples, this valuable course textIntroduction to Probability Models provides the reader with a comprehensive course in the subject, from foundations to advanced topics.

  • pH Deregulation as the Eleventh Hallmark of Cancer

    • 1st Edition
    • Tomas Koltai + 6 more
    • English
    pH Deregulation as the Eleventh Hallmark of Cancer presents key concepts about pH deregulation in a concise and straight-forward manner. The book discusses topics such as pH regulation and metabolism, sodium hydrogen exchanger, monocarboxylate transporter, V-ATPase proton pump, carbonic anhydrases, and voltage gated sodium channels. In addition, it covers clinical and therapeutic implications and future perspectives. This is a valuable resource for researchers, oncologists, students and members of the biomedical and medical fields who want to learn more about the role of pH deregulation in cancer treatment. pH deregulation can improve the outcome of classical treatments without adding toxicity to them, and the book shows that treating the pH peculiarities of cancer is simple and can be performed with existing drugs. Based on the classification of tumor malignancy in ten hallmarks, the authors put pH deregulation at the spotlight and separated from metabolic reprogramming due to its impact on all other hallmarks, proposing it as an additional characteristic to evaluate and fight cancer.

  • Advances in Resting-State Functional MRI

    Methods, Interpretation, and Applications
    • 1st Edition
    • Jean Chen + 1 more
    • English
    Advances in Resting-State Functional MRI: Methods, Interpretation, and Applications gives readers with basic neuroimaging experience an up-to-date and in-depth understanding of the methods, opportunities, and challenges in rs-fMRI. The book covers current knowledge gaps in rs-fMRI, including "what are biologically plausible brain networks," "how to tell what part is noise," "how to perform quality assurance on the data," "what are the spatial and temporal limits of our ability to resolve FC," and "how to best identify network features related to individual differences or disease state". This book is an ideal reference for neuroscientists, computational neuroscientists, psychologists, biomedical engineers, physicists and medical physicists. Both new and more advanced researchers alike will be able to discover new information distilled from the past decade of research to become well-versed in rs-fMRI-related topics.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 123
    • English
    Advances in Applied Microbiology, Volume 123 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Diagnostic Molecular Biology

    • 2nd Edition
    • Chang-Hui Shen
    • English
    Diagnostic Molecular Biology, Second Edition provides an up-to-date comprehensive overview of the latest advances in molecular diagnostics and the fundamental molecular aspects in this area. The book delves into the essential principles behind the transmission and expression of genetic information, including nucleic acids, proteins, and chromosomes, specifically their genome structure, life cycle, and evolution. The latest methods and instrumentation in the field are examined with detailed procedures and explanations provided for each technique. A range of techniques are also investigated, such as those used in sequencing analysis, genome and transcriptome analysis, and nucleic acid amplitification techniques. This book covers the collection, isolation, and purification of DNA, RNA, and protein from different sources. Additionally, discussion on the applications of next-generation sequencing (NGS) and the role of NGS in the future of precision medicine is included. The book also examines the use of molecular diagnostics for chromosomal disorders, inherited diseases, and infectious diseases. Moreover, this new edition features recent advances in the detection of respiratory virus infections in humans, including that of SARS-CoV2. Diagnostic Molecular Biology, Second Edition, is an ideal reference for researchers, lab technicians, and students in medical laboratory science, molecular biology, microbiology, virology, and related fields.

  • High Pressure Thermal Processing

    • 1st Edition
    • Kai Knoerzer + 1 more
    • English
    High Pressure Thermal Processing provides a detailed understanding on the technology itself, what it can be used for, and the benefits of the technology over conventional processing. From an academic perspective, all sections clearly outline the intricacies of the technology, new applications (other than for spore inactivation) and how technology related process variables impact on food, quality attributes, textures, safety, and chemical aspects, etc. From a manufacturer perspective, throughout the product development stage and the actual commercial implementation, the book content will assist users greatly in doing this efficiently and safely.Within a single reference book, this book reaches researchers in academia who face the challenge to drive the science and assist the manufacturers to commercialize these new technologies. It is also ideal for regulators around the world who need to assess these new technologies and implement guidelines for manufacturers.

  • Connectome Analysis

    Characterization, Methods, and Analysis
    • 1st Edition
    • Markus D. Schirmer + 2 more
    • English
    Connectome Analysis: Characterization, Methods, and Analysis is a comprehensive companion for the analysis of brain networks, or connectomes. The book provides sources of constituent structural and functional MRI signals, network construction and practices for analysis, cutting-edge methods that address the latest challenges in neuroscience, and the fundamentals of network theory in the context of giving practical methods for building connectomes for analysis. Emphasis is placed on quality control of the individual analysis steps. Subsequent chapters discuss networks in neuroscience in clinical and general populations, including how findings are related to underlying neurophysiology and neuropsychology.This book is aimed at students and early-career researchers in brain connectomics and neuroimaging who have a background in computer science, mathematics and physics, as well as more broadly to neuroscientists and psychologists who want to start incorporating connectomics into their research.

  • ICC Handbook of 21st Century Cereal Science and Technology

    • 1st Edition
    • Peter R. Shewry + 2 more
    • English
    ICC Handbook of 21st Century Cereal Science and Technology highlights the importance of cereals, presenting insights into the foundational structure of cereal grains, including potential contamination factors that can negatively impact cereal and grain yield. Focusing on the eight major cereal crops – wheat, maize, rice, barley, sorghum and millets, oats, rye and pseudocereals, this is the only available reference to provide standardized coverage for detailed comparison. Written by a global team of expert editors and contributors, the book provides practical insights into the utilization of cereals, grains and safety assessments. This International Association for Cereal Science and Technology endorsed volume continues their commitment to international cooperation through the dissemination of knowledge, conducting research and developing standard methods.

  • Partial Differential Equations and Applications

    A Bridge for Students and Researchers in Applied Sciences
    • 1st Edition
    • Hong-Ming Yin
    • English
    Partial Differential Equations and Applications: A Bridge for Students and Researchers in Applied Sciences offers a unique approach to this key subject by connecting mathematical principles to the latest research advances in select topics. Beginning with very elementary PDEs, such as classical heat equations, wave equations and Laplace equations, the book focuses on concrete examples. It gives students basic skills and techniques to find explicit solutions for partial differential equations. As it progresses, the book covers more advanced topics such as the maximum principle and applications, Green’s representation, Schauder’s theory, finite-time blowup, and shock waves. By exploring these topics, students gain the necessary tools to deal with research topics in their own fields, whether proceeding in math or engineering areas.

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