Advances in Clinical Chemistry
- 1st Edition, Volume 118 - January 25, 2024
- Imprint: Academic Press
- Editor: Gregory S. Makowski
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 9 5 6 2 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 5 6 3 - 8
Advances in Clinical Chemistry, Volume 118, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scient… Read more
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Request a sales quoteAdvances in Clinical Chemistry, Volume 118, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, including chapters on Advances in Endotoxin Analysis, Molecular biology of SARS-CoV-2 and techniques of diagnosis and surveillance, Osteopontin in Cancer, Gastrointestinal Hormones: History, Biology, and Measurement, Natriuretic Peptide Testing Strategies in Heart Failure: a 2023 Update, and Defining Allowable Total Error Limits in the Clinical Laboratory.
- Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science
- Authored by world renowned clinical laboratory scientists, physicians, and research scientists
- Presents the international benchmark for novel analytical approaches in the clinical laboratory
Clinical Laboratory Professionals, Physicians and Research Scientists
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Advances in endotoxin analysis
- Graphical Abstract
- Abstract
- 1 Introduction
- 2 Classical methods
- 3 Alternate methods
- 4 Modern approaches
- 5 Electrochemical methods
- 6 Nanomaterial-based methods
- 7 Cell-based assays
- 8 Quartz crystal microbalance assays
- 9 High-performance liquid chromatography (HPLC)
- 10 Summary and future perspectives
- References
- Chapter Two: Molecular biology of SARS-CoV-2 and techniques of diagnosis and surveillance
- Abstract
- 1 Introduction
- 2 Genomic structure of SARS-CoV-2
- 3 Mutations of SARS-CoV-2, variants of concern and interest
- 4 Molecular diagnosis of SARS-CoV-2 by RT-PCR
- 5 Surveillance techniques for SARS-CoV-2
- 6 Conclusions
- References
- Chapter Three: Osteopontin in cancer
- Abstract
- 1 Introduction
- 2 OPN structure
- 3 Mode of action
- 4 Osteopontin in human cancer
- 5 Osteopontin as a potential biomarker in cancer
- 6 Osteopontin as a non-invasive biomarker
- 7 Conclusion and future perspectives
- Acknowledgment
- References
- Chapter Four: Gastrointestinal hormones: History, biology, and measurement
- Abstract
- 1 Introduction
- 2 Advances in gastrointestinal endocrinology – the history
- 3 The new biology of gastrointestinal hormones
- 4 Targets for gastrointstinal hormones
- 5 Methods for measurement of gastrointestinal hormones
- 6 Concentrations of gastrointestinal hormones in plasma
- 7 Clinical measurement of gastrointestinal hormones
- 8 Summary and perspective
- Acknowledegement
- References
- Chapter Five: Natriuretic peptide testing strategies in heart failure: A 2023 update
- Abstract
- 1 Introduction
- 2 Physiology of NPs in HF
- 3 Clinical utility of serial NP measurements
- 4 Interpretation of significantly increased NPs
- 5 Unexpectedly low NPs
- 6 Identifying patients at risk of HF with NP testing: guideline updates
- 7 Conclusions
- References
- Chapter Six: Defining allowable total error limits in the clinical laboratory
- Abstract
- Abbreviations
- 1 Introduction
- 2 ATE models
- 3 ATE set by professional experts
- 4 ATE set by regulatory bodies
- 5 Considerations in selecting ATE
- 6 Practical application of ATE: comparison of total analytical error (TAE) with allowable total error (ATE)
- 7 Summary
- References
- Index
- Edition: 1
- Volume: 118
- Published: January 25, 2024
- Imprint: Academic Press
- No. of pages: 246
- Language: English
- Hardback ISBN: 9780443295621
- eBook ISBN: 9780443295638
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USARead Advances in Clinical Chemistry on ScienceDirect