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Elsevier

Academic Press

  • The Biology of Ageing: From Hallmarks to Drugs

    • 1st Edition
    • Volume 1
    • Richard Faragher
    • English
    The Biology of Ageing: From Hallmarks to Drugs provides a series of reviews covering multiple aspects of the translational pipeline as interventions in the biology of ageing itself become a clinical reality. New chapters cover Cellular senescence and NAD+: what are the links?, Biomarker for ageing: potential and pitfalls, What chemists offer to ageing research, You are what you eat – or are you? Exploring dietary versus topical anti-oxidants in skin ageing, Clinical trials: A simple guide for gerontologists, Towards an ethical framework for geroscience, and more. The book explores links between known ageing mechanisms and new interventions, agents and actions at the nutraceutical-drug divide, the challenges and opportunities provided by biomarkers and chemistry- biology interface and lastly the ethical and operational challenges of clinical trials in the age of translational geroscience.

  • Social and Communicative Functioning in Populations with Intellectual Disability: Rethinking Measurement

    • 1st Edition
    • Volume 64
    • English
    Social and Communicative Functioning in Populations with Intellectual Disability: A Developmental Perspective, Volume 65 in the International Review of Research in Developmental Disabilities series, focuses on social and communicative functioning with a particular emphasis on people with intellectual disability. The volume brings together international researchers across disciplines to highlight innovative approaches to holistically describe social and communicative abilities in this population including teleassessment, self-report, and community-engaged research designs. Through a lifespan approach, key issues are raised related to social and communicative functioning across a range of communication modalities from infancy through adulthood.Additional chapters cover Adaptation of in-person tools for remote assessment of infants and toddlers with social communication concerns in community-based settings, Measuring social communication in people with ID who use minimal speech: Differences across the lifespan, and Social Inclusion of Adults with IDD: Toward Belonging, Building a Life: Examining the advocacy and social experiences of students with IDD in inclusive postsecondary education.

  • Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-Morbidity Factors Part B

    • 1st Edition
    • Volume 172
    • English
    Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors, Part B, Volume 172 in the International Review of Neurobiology series, includes chapters on Spinal cord injury induced exacerbation of Alzheimer's disease pathophysiology in the cord is reduced by topical application of nanowired cerebrolysin and antibodies to tumor necrosis factor alpha, Nanodelivery of histamine H3 receptor inverse agonist BF-2549 with clobenpropit a H3 receptor antagonist and H4 receptor agonist induced neuroprotection in spinal cord injury is potentiated by antioxidant compound H-290/51, and Neuromodulation and quality of life for patient with spasticity after spinal cord injury, and more.Other sections cover Efficacy of invasive and non-invasive methods for the treatment of Parkinson´s disease: nanodelivery and enriched environment, Co-administration of DL-3-n-butylphthalid... and neprilysin is neuroprotective in Alzheimer disease associated with brain injury, Nicotine Neurotoxicity Exacerbation following Engineered Ag and Cu (50-60 nm) nanoparticles intoxication, and Neuroprotection with nanowired delivery of antioxidant compound H-290/51 together with serotonin 5-HT3 receptor antagonist ondansetron.

  • Advances in Virus Research

    • 1st Edition
    • Volume 117
    • English
    Advances in Virus Research, Volume 117, the latest release in a series that highlights new advances in the field, includes invaluable updates written by an international board of authors. Chapters in this new release include Pathogenesis of neuroinvasive flaviviruses, Cellular entry and egress of astroviruses, Rift Valley Fever virus entry and infection, and more.

  • Encyclopedia of Food Safety

    • 2nd Edition
    • Geoffrey W Smithers
    • English
    Encyclopedia of Food Safety, Second Edition, Four Volume Set provides an authoritative one-stop reference work covering all aspects of the field. Specific focus lies in the book's coverage of key industry developments over the last ten years, including: (i) detailed understanding of infectious agents and toxins and their route into the food chain; (ii) sophisticated detection and identification methods; (iii) effective control mechanisms, like heat treatment, refrigeration and sanitizers; (iv) education of food processors, handlers and consumers about safe food handling practices; (v) sanctioned food production, processing, storage and transport control protocols, like HACCP; and (vi) a strong policy and regulatory environment. With approximately 270 outstandingly written chapters from the world’s leading experts in food science, the book covers all aspects of food safety along the entire food chain and in one complete work, thus providing the ideal reference tool for professionals working across the multiple scientific disciplines and technologies that constitute modern food safety.

  • Artificial Intelligence in the Age of Neural Networks and Brain Computing

    • 2nd Edition
    • Robert Kozma + 3 more
    • English
    Artificial Intelligence in the Age of Neural Networks and Brain Computing, Second Edition demonstrates that present disruptive implications and applications of AI is a development of the unique attributes of neural networks, mainly machine learning, distributed architectures, massive parallel processing, black-box inference, intrinsic nonlinearity, and smart autonomous search engines. The book covers the major basic ideas of "brain-like computing" behind AI, provides a framework to deep learning, and launches novel and intriguing paradigms as possible future alternatives. The present success of AI-based commercial products proposed by top industry leaders, such as Google, IBM, Microsoft, Intel, and Amazon, can be interpreted using the perspective presented in this book by viewing the co-existence of a successful synergism among what is referred to as computational intelligence, natural intelligence, brain computing, and neural engineering. The new edition has been updated to include major new advances in the field, including many new chapters.

  • Epigenetics in Human Disease

    • 3rd Edition
    • Trygve O. Tollefsbol
    • English
    Epigenetics in Human Disease, Third Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. From molecular mechanisms and epigenetic technology to clinical translation of recent research, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders, with an emphasis throughout on understanding and application of key concepts in new research and clinical practice. Fully revised and up-to-date, this Third Edition discusses topics of current interest in epigenetic disease research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, microRNA in cancer, epigenetic approaches to control obesity, epigenetics and airway disease, and epigenetics in cardiovascular disease. Further sections explore online epigenetic tools and datasets; early-life programming of epigenetics in age-related diseases; the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer’s disease, respiratory diseases, and many other human maladies. In addition, each chapter now includes chapter summaries, definitions, and vibrant imagery and figures to reinforce understanding, as well as step-by-step methods and disease research case studies.

  • Renewable Energy - Volume 2: Wave, Geothermal, and Bioenergy

    Definitions, Developments, Applications, Case Studies, and Modelling and Simulation
    • 1st Edition
    • Abdul Ghani Olabi
    • English
    Renewable Energy - Volume 2: Wave, Geothermal, and Bioenergy: Definitions, Developments, Applications, Case Studies, and Modelling and Simulation is the next volume in this comprehensive resource for those wanting an extensive reference on these specialized technologies. Providing a structured approach to the emerging technologies and advances in implementation of Geothermal and Biofuels systems, this reference addresses geothermal and biofuel coverage in a logical and accessible arrangement. From definitions to developments in technology and applications, to case studies, modelling examples and lifecycle analysis, this book considers the most requested and desirable practical elements of geothermal and biofuel technologies from an applied perspective. This coordinated approach allows for stand alone, accessible and functioning chapters dedicated to particular energy sources. This is a suitable reference for students and post-doctoral research fellows working on projects related to renewable energy, sustainability and energy system design.

  • Biophysics at the Nanoscale

    Applications of Functional Materials
    • 1st Edition
    • Adil Denizli
    • English
    Biophysics at the Nanoscale: Applications of Functional Materials explores how nanomaterials and nanotechnology can be used effectively in biophysics. The book introduces the structures and functions of nanoscale-based materials from a biophysical perspective while also discussing nanotechnology opportunities for their purposeful manipulation and the integration of nanoscale-based materials with current top-notch tools and platforms to ultimately facilitate their potential applications in the areas like biomedicine and the pharmaceutical sciences. The book provides the most impactful research and current techniques and strategies. With contributions from an international group of experts in the field, the book is highly informative and is a reference point for learning key knowledge and information.

  • Hybrid Rocket Propulsion Design Handbook

    • 1st Edition
    • Ashley Chandler Karp + 1 more
    • English
    Hybrid Rocket Propulsion Design Handbook provides system scaling laws, design methodologies, and a summary of available test data, giving engineers all the tools they need to develop realistic hybrid system designs.Important supporting theory from chemistry, thermodynamics, and rocket propulsion is addressed, helping readers from a variety of backgrounds to understand this interdisciplinary subject. This book also suggests guidelines for standardized reporting of test data, in response to difficulties researchers have in working with results from different research institutes.

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