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Academic Press

Modernizing Global Health Security to Prevent, Detect, and Respond
1st Edition
Scott J.N. McNabb + 2 more
English
Modernizing Global Health Security to Prevent, Detect, and Respond explores—through thoughtful, thorough, and diverse scientific review and analyses—factors that have led to recent public health emergencies and offers a vision for a better protected global environment. The authors consider the history of global health security, governance, and legal structures with an eye toward novel approaches for the present and future. The book presents a vision for a more protected and safer global public health future (with the actions needed to achieve it) to prevent, detect, and respond to (re)emerging threats. Its aim is to chart a way forward with the understanding that future pandemics must and can be prevented. Major topics examined from a public health perspective include global health security; the growing concept of One Health; epidemic and pandemic prevention, detection, and response; reviews of past (e.g., Ebola, MERS-CoV, Zika, and COVID-19) public health emergencies of international concern; roles of information and communication technology; humanmade public health threats; and legal and ethical issues (e.g., viral sovereignty, trust, and transparency). Modernizing Global Health Security to Prevent, Detect, and Respond provides the academic substance and quality for researchers and practitioners to deeply understand the why of health emergencies, and most importantly—what we can and should do now to prepare.
Diagnostic Molecular Pathology
A Guide to Applied Molecular Testing
2nd Edition
William B. Coleman + 1 more
English
Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease.
Molecular Pharmaceutics and Nano Drug Delivery
Fundamentals and Challenges
1st Edition
Umesh Gupta + 1 more
English
Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource for both beginners and established scientists, bringing fundamental knowledge about key challenges of these carriers down to the molecular level. The book satisfies the need of availability of literature at single platform with the detailed knowledge to understand crucial aspects, such as regulatory, clinical, toxicological and the formulation requirements of these carriers. This is a valuable resource for graduates, pharmaceutical researchers and anyone working on aspects of pharmaceutics, molecular pharmaceutics and nano-drug/gene delivery. So called ‘novel drug delivery systems’ are numerous, with each having different approaches to their production, characterization and evaluation. The proper understanding of these dosage forms, as well as their critical attributes such as toxicity and regulatory requirements are aspects which researchers should know before they begin working on these carriers. This book provides this critical information.
Advances in Physical Organic Chemistry
1st Edition
Volume 57
English
Advances in Physical Organic Chemistry, Volume 57 presents the latest reviews of recent work in physical organic chemistry, providing a valuable source of information that is ideal not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. The book's hallmark is its quantitative, molecular level understanding of phenomena across a diverse range of disciplines.
New Directions in Addiction Science
1st Edition
Volume 79
English
New Directions in Addiction Science, Volume 79 in The Psychology of Learning and Motivation series, features empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning, to complex learning and problem-solving.
Modern Methods of Drug Design and Development
1st Edition
Volume 690
English
Modern Methods of Drug Design and Development, a volume in the Methods in Enzymology series highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Recombinant protein purification for structural and kinetic studies, Steady-state kinetic analysis of reversible enzyme inhibitors, Steady-State Enzyme Kinetics, Analysis of enzyme kinetic data using ICEKAT, NMR techniques in drug discovery, Dynamic simulations and pre-steady state kinetics to guide drug discovery, Design and assay of substrate-product analogues for racemases and epimerases, Sensitive high throughput methods to screen for P450 inhibition: A- MI complex forming drugs, and more. Other chapters cover Sensitive high throughput methods to screen for P450 inhibition: B-Heme loss causing drugs, Discovery and development of inhibitors of acetyltransferase Eis to combat Mycobacterium tuberculosis, Crystallographic fragment screening in academic cancer drug discovery, Fast fragment- and compound-screening pipeline at the Swiss Light Source, Chemical biology, enzymology and drug discovery, PROTACs, Proximity-Induced Pharmacology (PROTACs), and much more.
Clinician’s Guide to Sexuality and Autism
A Guide to Sex Education for Individuals with Autism Spectrum Disorders
1st Edition
Jessica Cauchi + 3 more
English
Clinician’s Guide to Sexuality and Autism: A Guide to Sex Education for Individuals with Autism Spectrum Disorders is the first book to provide clinicians with comprehensive curriculum of sexuality education skills for people with Autism Spectrum Disorders (ASD). Starting with the importance of teaching sexuality skills to people with autism, this book provides an outline and overview of the recommended teaching strategies (e.g., Behavioral Skills Training, Cool vs. Not Cool, video modeling). This book also reviews the fourteen skill domains directly related to sexuality, including the key skills one should acquire in each domain. A timeline focusing on what skills should be targeted at what age and what skills to teach across the lifespan are also discussed. The curriculum covers domains that are often neglected in sex education for people with different disabilities in general (e.g. values, types of relationships, gender identity, or preferences). Additionally, this curriculum addresses component skills of sexuality in a way that allows early teaching to build upon areas of learning systematically over time, thus likely to have an improvement in teaching over time.
Microbiome Drivers of Ecosystem Function
1st Edition
Javid A. Parray + 2 more
English
Microbiome Drivers of Ecosystem Function, the latest release in the Microbiome Research in Plants and Soil series, focuses on advancements in microbial technologies towards harnessing the microbiome for improved crop productivity and health. The book provides insights into the diversity of endophytic microbiomes and their potential utility in agricultural production. As increased crop yield through chemical interventions have limit thresholds and alternative, natural, and/or integrated approaches are increasingly needed, this book serves as an ideal reference for researchers and students in the fields of agricultural biotechnology, biochemistry, environmental science, plant biology, agricultural sciences, and agricultural engineering.Microbia... inoculants provide ways in which food production efficiency can be improved. Plant growth-promoting soil organisms increase net crop uptake of soil nutrients, resulting in larger crops and higher yields of harvested food. These and other symbiotic associations between plants and microbes can ultimately be exploited for the increased food production necessary to feed the world, in addition to creating safer farming techniques that minimize ecological disruption.
Pharmacognosy
Fundamentals, Applications, and Strategies
2nd Edition
Simone Badal McCreath + 1 more
English
Pharmacognosy: Fundamentals, Applications and Strategies, Second Edition represents a comprehensive compilation of the philosophical, scientific and technological aspects of contemporary pharmacognosy. The book examines the impact of the advanced techniques of pharmacognosy on improving the quality, safety and effectiveness of traditional medicines, and how pharmacokinetics and pharmacodynamics have a crucial role to play in discerning the relationships of active metabolites to bioavailability and function at the active sites, as well as the metabolism of plant constituents. Structured in seven parts, the book covers the foundational aspects of Pharmacognosy, the chemistry of plant metabolites, their effects, other sources of metabolites, crude drugs from animals, basic animal anatomy and physiology, technological applications and biotechnology, and the current trends in research. New to this edition is a chapter on plant metabolites and SARS-Cov-2, extensive updates on existing chapters and the development of a Laboratory Guide to support instructors execute practical activities on the laboratory setting.
Advances in Clinical Chemistry
1st Edition
Volume 116
Gregory S. Makowski
English
Advances in Clinical Chemistry, Volume 116, the latest release in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists.

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