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Academic Press

  • Bioactive Lipid Mediators in Cardiopulmonary Pharmacology

    • 1st Edition
    • Volume 97
    • English
    Bioactive Lipid Mediators in Cardiopulmonary Pharmacology, Volume 97 updates readers on topics surrounding Bioactive lipid mediators. These mediators are involved in a vast array of signaling pathways that regulate both physiological and pathophysiological responses. Chapters in this new release include Cyclooxygenases and Vascular Function, Cyclooxygenases and Platelet Function, Eicosanoids and Cardiomyopathies, Cytochrome P450 Bioactive Lipids in the Heart, Epoxide Hydrolase and Leukotoxin in the Heart and Lung, Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response, Bioactive Lipids in Hypertension, Cytochrome P450 Metabolites and Angiogenesis, 20-Hydroxyeicosatetr... Acid and Vascular Function, and more. Other critical sections cover Cytochrome P450 Eicosanoids and the Brain, Omega-3 Oxylipids, Resolvins, Lipoxins and Inflammation, Endocannabinoids as Bioactive Metabolites, and Oxylipins and Aspirin Exacerbated Respiratory Disease.
  • Epigenetics in Health and Disease part B

    • 1st Edition
    • Volume 198
    • English
    Epigenetics in Health and Disease, Volume 198 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on Computational biology in epigenetics, Artificial intelligence and machine learning in epigenetics, CRISPR-dCas9 Systems for Epigenetic Editing for Therapeutic Applications, Epigenetics in heredity disease, Epigenetics in cancer development, diagnosis and therapy, Microbiota and epigenetics: health impact, Histone deacetylase (HDACs) Inhibitors: Clinical applications, Early epigenetic markers for precision medicine, Epigenetics of neurological diseases, Epigenetic Regulons in Alzheimer’s disease, and Epigenetics in epilepsy.
  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 104
    • Fidel Toldra
    • English
    Advances in Food and Nutrition Research, Volume 104 provides the latest advances on emerging bioactive compounds with putative health benefits and their controlled release and application in foods and nutraceuticals, as well as up-to-date information on food technologies, including 3D printing, safety of raw materials, and viruses in foods. Chapters in this new release cover Development and Application of Lipidomics for Food Research, Multi-omics fingerprints for food geographical origin identification and authentication, and Mass Spectrometry-based Techniques for Identification of Compounds in Milk and Meat Matrix, Micro- and Nanoencapsulation of Natural Phytochemicals: Challenges and Recent Perspectives for the Food and Nutraceuticals Industry Applications. Additional sections delve into the Effect of type and interfacial modification of emulsions on the protection and delivery of nutraceuticals, Nutricosmetics: a new frontier in bioactive peptides’ research towards skin aging, In vitro digestion models in the design of safe and nutritious foods, and Informing consumers optimally about their food: issues with and potential solutions for different types of information, their sources and consumers’ trust.
  • Sex, Gender, and Epigenetics

    From Molecule to Bedside
    • 1st Edition
    • Marianne Legato J. + 2 more
    • English
    Sex, Gender, and Epigenetics: From Molecule to Bedside explores our expanding knowledge of the science of epigenetics in which gene expression is modified as a consequence of small chemical additions to various components of the genome. The book provides an overview of the field, describing the epigenetic phenomena that unite biological sex and environmental experience to create the unique phenome of each individual. The book also analyzes the impact of ancestors’ environmental experience on subsequent generations through the sex-specific transmission of environmentally induced epigenetic modifications. Here, international leaders in the field discuss both sex-specific normal physiology and the experience of disease, with chapters dedicated to fetal programming, the microbiome, cancer, bipolar disorder and schizophrenia, embryogenesis, and oocyte aging, among other topics.
  • Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development

    • 1st Edition
    • Kunal Roy
    • English
    Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development aims at showcasing different structure-based, ligand-based, and machine learning tools currently used in drug design. It also highlights special topics of computational drug design together with the available tools and databases. The integrated presentation of chemometrics, cheminformatics, and machine learning methods under is one of the strengths of the book.The first part of the content is devoted to establishing the foundations of the area. Here recent trends in computational modeling of drugs are presented. Other topics present in this part include QSAR in medicinal chemistry, structure-based methods, chemoinformatics and chemometric approaches, and machine learning methods in drug design. The second part focuses on methods and case studies including molecular descriptors, molecular similarity, structure-based based screening, homology modeling in protein structure predictions, molecular docking, stability of drug receptor interactions, deep learning and support vector machine in drug design. The third part of the book is dedicated to special topics, including dedicated chapters on topics ranging from de design of green pharmaceuticals to computational toxicology. The final part is dedicated to present the available tools and databases, including QSAR databases, free tools and databases in ligand and structure-based drug design, and machine learning resources for drug design. The final chapters discuss different web servers used for identification of various drug candidates.
  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 80
    • Pedro J. Perez
    • English
    Advances in Organometallic Chemistry, Volume 80, the latest release in this longstanding serial, is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. It is ideal for a wide range of researchers involved in organometallic chemistry, with this updated release including chapters on Organometallic-like reactivity of group 10 metal-heteroatom sigma bonds, Organometallic interactions between metal nanoparticles and carbon-based molecules: a surface reactivity rationale, Group VI Allenylidene Complexes, and more.
  • Artificial Intelligence in Healthcare and COVID-19

    • 1st Edition
    • Parag Chatterjee + 1 more
    • English
    Artificial Intelligence in Healthcare and COVID-19 showcases theoretical concepts and implementational and research perspectives surrounding AI. The book addresses both medical and technological visions, making it even more applied. With the advent of COVID-19, it is obvious that leading universities and medical schools must include these topics and case studies in their usual courses of health informatics to keep up with the pace of technological and medical advancements. This book will also serve professors teaching courses and industry practitioners and professionals working in the R&D team of leading medical and informatics companies who want to embrace AI and eHealth to fight COVID-19. Since AI in healthcare is a comparatively new field, there exists a vacuum of literature in this field, especially when applied to COVID-19. With the area of AI in COVID-19 being quite young, students and researchers usually face a struggle to rely on the few published papers (which are obviously too specific) or whitepapers by tech-giants (which are too wide).
  • Yasargil Microneurosurgery Study Guide

    Books I, II, IIIA, IIIB, IVA, and IVB
    • 1st Edition
    • Leonard Kranzler + 1 more
    • English
    Yaşargil Microneurosurgery Study Guide is designed for effective learning and study of the neurosurgical principles contained in seminal microneurosurgery textbooks. From normal microsurgical anatomy to aneurysms, arteriovenous malformations, and CNS tumor microsurgery, this study guide provides a question-and-answer format to knowledge of the background, anatomy, and techniques of microneurosurgery. This work is a practical guide to the application of microneurosurgery to a variety of brain conditions, including intracranial aneurysms, extrinsic and intrinsic tumors, while providing guidance on instrumentation and equipment, neuroanesthesia, complications, and more. This practical book is ideal for neurosurgeons, neurologists, neuroanatomists, and other technical experts with a clinical interest in brain microsurgery.
  • Real-Time Simulation Technology for Modern Power Electronics

    • 1st Edition
    • Hao Bai + 3 more
    • English
    Real-Time Simulation Technology for Modern Power Electronics provides an invaluable foundation and state-of-the-art review on the most advanced implementations of real-time simulation as it appears poised to revolutionize the modeling of power electronics. The book opens with a discussion of power electronics device physic modeling, component modeling, and power converter modeling before addressing numerical methods to solve converter model, emphasizing speed and accuracy. It discusses both CPU-based and FPGA-based real-time implementations and provides an extensive review of current applications, including hardware-in-the-loop and its case studies in the micro-grid and electric vehicle applications. The book closes with a review of the near and long-term outlooks for the evolving technology. Collectively, the work provides a systematic resource for students, researchers, and engineers in the electrical engineering and other closely related fields.
  • Colorectal Disorders and Diseases

    An Infographic Guide
    • 1st Edition
    • Constantine P. Spanos
    • English
    Colorectal Disorders and Diseases: An Infographic Guide provides a comprehensive and up-to-date overview of the most relevant diagnostic modalities, staging, classification systems and current therapeutic modalities for colorectal disorders and diseases. With coverage from incontinence, prolapse, anal fissures, and cancer, this reference offers a wide-ranging guide to colorectal disorders and diseases. The use of engaging infographics throughout provides an inviting “at-a-glace” perspective of the subject, allowing users to retain a large amount of information without the need to scroll through large text or complex algorithms. This is an important reference for clinicians, surgeons and medical students rotating in colorectal surgery as well as scientists that need a quick reference for research of colorectal issues including epidemiology, diagnosis and therapy.