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Academic Press

  • Multiphysics of Wind Turbines in Extreme Loading Conditions

    • 1st Edition
    • Arash Soleiman Fallah + 2 more
    • English
    Multiphysics of Wind Turbines in Extreme Loading Conditions addresses the extreme transient loading of wind turbines through a multiphysics modeling approach, notably by considering the dynamic effects and the nonlinearities of the physics involved in such situations. The book forms the basis for understanding multiphysic numerical simulations conducted on onshore and offshore wind turbines and subjected to extreme loading conditions, including storms, earthquakes, blasts, impacts, and tsunamis. The multiphysics approaches used in this book are explained in each chapter, with algorithms then turned into numerical codes to attain a realistic picture of the dynamic response in each scenario. With numerical methods and loading data explained, the complexity of potential problems encountered when extreme dynamic loads are discussed, along with loading types and their effects. The book fills a specific niche in wind power, namely extreme transient loading of wind turbine, offering information and industrial practices as wind energy makes it useful to practice engineers, designers, undergraduate and graduate students.

  • Living Donor Organ Transplantation

    • 2nd Edition
    • Rainer W.G. Gruessner + 1 more
    • English
    **Selected for 2025 Doody’s Core Titles® in Transplantation Surgery**Living Donor Organ Transplantation, Second Edition puts the entire discipline in perspective while guiding readers step-by-step through the most common organ transplant surgeries. This two-volume set is organized into five cohesive parts, and featuring numerous surgical illustrations, this sourcebook delivers an incisive look at every key consideration for general surgeons who perform transplantations, from patient selection to recipient workup and outcomes. The books emphasize the most humanitarian approaches and provide content on living donor uterus transplantation, new operative techniques, including the use of robotic and minimally invasive transplant procedures, new immunosuppressive regimens, new protocols of tolerance induction, including stem cell therapy and transplantation, and more.Chapter authors are international leaders in their fields and represent institutions from four continents (Americas: USA, Argentina, Brazil, Canada; Europe: France, Germany, Italy, Spain, Sweden, UK; Asia: China, Japan, Korea, Taiwan; Australia).

  • Insulin

    Deficiency, Excess and Resistance in Human Disease
    • 1st Edition
    • Andrew J. Krentz
    • English
    Insulin: Deficiency, Excess and Resistance in Human Disease provides an overview of the role of insulin in the pathogenesis of prevalent non-communicable diseases such as obesity, type 2 diabetes, cardiovascular disease, and cancer, along with a comprehensive review of insulin replacement therapies and novel cardioprotective and insulin-sensitizing drugs. Notable advances in precision diagnosis and therapy for single gene subtypes of diabetes in recent years are also discussed.The discovery of insulin and its lifesaving introduction into clinical practice is one of the most celebrated accomplishments of medical science. However, despite decades of progress and major technical advances, the goal of providing insulin replacement therapy that truly mimics normal physiology remains elusive.

  • Phytomanagement as a nature-based solution for polluted soils

    • 1st Edition
    • Volume 109
    • English
    Phytoremediation, Volume 109 in the Advances in Botanical Research series, highlights new advances on phytoremediation. Chapters in this new release include Plant-microbiome interactions and their role in recovering ecosystems from organic contaminants, Aquatic macrophytes: the potential candidate for polluted water phytoremediation, Rare earth elements in plants : uptake, accumulation and tolerance, Poplar as a woody model for phytomanagement strategies, Plant-based remediation of industrially contaminated soils: principles and case study, Phytoremediation of Arsenic contaminated soils by hyperaccumulating fern Pteris vittata, Effects of phytomanagement of heavy metal polluted soils with woody plants on functional activity and functional genes abundance and diversity, and more.Other chapters cover Cucurbits for cleanup of soils contaminated with persistent and emerging organic pollutants: state of the art, future perspectives and challenges, Phytoremediaton in the Guadiamar Green Corridor (SW Spain): trends of trace element uptake by plants and effects on soil fungal diversity, and Metal hyperaccumulation mechanisms in plants.

  • Immunobiology of COVID-19

    • 1st Edition
    • Volume 202
    • English
    Immunobiology of COVID19, Volume 202 in the Progress in Molecular Biology and Translational Science Series provides a comprehensive and in-depth exploration of the SARS-CoV-2 virus and its impact on human health. Written by a team of expert contributors, the book covers various aspects of the virus, including its structure, lifecycle, and genomic replication. It delves into the epidemiology of COVID-19, comparing it with other related coronaviruses and discussing the concept of herd immunity. The structural biology of SARS-CoV-2 is examined, with a focus on techniques such as electron microscopy and cryo-electron tomography. The book also explores the biology of SARS-CoV-2 variants and their immune evasion strategies. Furthermore, it delves into the pathogenesis of COVID-19, examining its multiorgan manifestations and the long-term effects of the disease. The innate and adaptive immune responses to SARS-CoV-2 are discussed in detail, along with the role of B cells and T cells in the immune response. The volume concludes with a look at future insights and potential developments in the field. Accompanied by illustrative diagrams and visuals, this volume will serve as a valuable resource for researchers, healthcare professionals, and anyone interested in understanding the intricate details of SARS-CoV-2 and its impact on global health.

  • Artificial Intelligence and Image Processing in Medical Imaging

    • 1st Edition
    • Walid A. Zgallai + 1 more
    • English
    Artificial Intelligence and Image Processing in Medical Imaging deals with the applications of processing medical images with a view of improving the quality of the data in order to facilitate better decision- making. The book covers the basics of medical imaging and the fundamentals of image processing. It explains spatial and frequency domain applications of image processing, introduces image compression techniques and their applications, and covers image segmentation techniques and their applications. The book includes object detection and classification applications and provides an overall background to statistical analysis in biomedical systems. The role of Machine Learning, including Neural Networks, Deep Learning, and the implications of the expansion of artificial intelligence is also covered. With contributions from prominent researchers worldwide, this book provides up-to-date and comprehensive coverage of AI applications in image processing where readers will find the latest information with clear examples and illustrations.

  • Parameter Estimation and Adaptive Control for Nonlinear Servo Systems

    • 1st Edition
    • Shubo Wang + 2 more
    • English
    Parameter Estimation and Adaptive Control for Nonlinear Servo Systems presents the latest advances in observer-based control design, focusing on adaptive control for nonlinear systems such as adaptive neural network control, adaptive parameter estimation, and system identification. This book offers an array of new, real-world applications in the field. Written by eminent scientists in the field of control theory, this book covers the latest advances in observer-based control design and provides fundamentals, algorithms, and key applications in the fields of power systems, robotics and mechatronics, flight, and automotive systems.

  • Safe Major Hepatectomy after Preoperative Liver Regeneration

    Preopearative PVE, Two-Satage Hepatetomy, ALPPS and Hepatic Vein Deprivation
    • 1st Edition
    • Yoshihiro Sakamoto + 1 more
    • English
    Safe Major Hepatectomy After Preoperative Liver Regeneration: Preoperative PVE, Two-Stage Hepatectomy, ALPPS and Hepatic Vein Deprivation provides both history and recent topics of major hepatectomy after liver regeneration—as well as the basic background of liver regeneration—allowin... liver surgeons, general surgeons, and hepatologists to increase the safety of major hepatectomy in patients suffering from advanced liver disease. This reference provides importance guidance to cutting edge topics, including the molecular mechanism of liver regeneration after preoperative portal vein embolization (PVE), two-stage hepatectomy, associating liver partition and portal vein occlusion for staged hepatectomy (ALPPS) and results of hepatic vein occlusion.The mortality rate after major hepatectomies is high worldwide and there is a need to establish a strategy for safe major hepatectomies, and hepatectomy after preoperative liver regeneration is a key process to prevent posthepatectomy liver failure (PHLF).

  • Immune Checkpoint Biology in Health and Disease

    • 1st Edition
    • Volume 382
    • English
    Immune Checkpoint Biology in Health and Disease, Volume 382 provides in-depth reviews on the latest progress concerning research on immune-checkpoint biology and its immunotherapeutic implications, especially in cancer. Topics connected to immune-checkpoint biology covered in this volume include Novel technologies for applying immune checkpoint blockers, Next-generation deconvolution of transcriptomic data to investigate the tumor microenvironment, Immune checkpoints targeting dendritic cells for antibody-based modulation in cancer, Immune checkpoint biology in health & disease: Immune checkpoint biology and autoimmunity in cancer patients, and much more.Other sections cover Recent advancements in tumor microenvironment landscaping for target selection and response prediction in immune checkpoint therapies achieved through spatial protein multiplexing analysis, Immune Modulation During Anti-Cancer Radio(immuno)therapy... and Preconditioning with immunogenic cell death-inducing treatments for subsequent immunotherapy.

  • Topology Optimization and AI-based Design of Power Electronic and Electrical Devices

    Principles and Methods
    • 1st Edition
    • Hajime Igarashi
    • English
    Topology optimization and AI-based design of power electronic and electrical devices provides an essential foundation in the emergent design methodology as it moves toward commercial development, including electrical devices as traction motors for electric motors, transformers, inductors, reactors, and power electronics circuits.Opening with an introduction to electromagnetism and computational electromagnetics for optimal design, this book outlines principles and foundations in finite element methods and illustrates numerical techniques useful for finite element analysis. It summarizes the foundations of deterministic and stochastic optimization methods, including genetic algorithm, CMA-ES, and simulated annealing for quantum and quantum-inspired optimization, alongside representative algorithms. The book goes on to discuss parameter optimization and topology optimization of electrical devices alongside current implementations including magnetic shields, 2D and 3D models of electric motors, and wireless power transfer devices. Finally, it concludes with a lengthy exposition of AI-based design methods, including surrogate models for optimization, Bayesian optimization, direct inverse modeling, deep neural networks, explainable AI, variational autoencoder, and integrated design methods using Monte Carlo tree searches for electrical devices and circuits.  

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