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Academic Press

Antioxidant Methods
A Guideline for Understanding and Determining Antioxidant Capacity
1st Edition
Francisco Avelino
English
Antioxidant Methods: A Guideline for Understanding and Determining AntioxidantCapacity summarizes the importance of antioxidants as a class of compounds withinnumerous areas of science and technology. The chapters elucidate diverse methodologiesfor assessing the antioxidant capacity of an antioxidant, while also exploring the correlationbetween its structural attributes and overall performance. Chapters include descriptions ofprotocols used to measure antioxidant capacity by different methods, highlighting experimentalsteps, bottlenecks, expected outcomes, advantages, limitations, and more.This is the perfect reference for biomedical science researchers looking for the right methodfor determining antioxidant capacity through the structure and functionalities of the compound,as well as the mechanisms involved in the antioxidant action.
Intelligent Packaging
Current Technologies and Applications
1st Edition
English
Intelligent Packaging: Current Technologies and Applications, Volume Six in the Developments in Food Quality and Safety series is the most up-to-date resource on topics such as Advances in the analysis of toxic compounds and control of food poisoning; Food fraud, traceability and authenticity; Revalorization of agrifood industry; Natural antimicrobial compounds and application to improve the preservation of food; Non-thermal processing technologies in the food industry; Nanotechnology in food production; and Intelligent packaging and sensors. This updated volume covers intelligent packaging by discussing the aspects of emerging technologies and strategies to obtain such packaging relevant to the development of traceable food products.Topics such as indicators, sensors, tracing devices, and intelligent packaging used in various food products, such as dairy, meat, fruits and vegetables are also explored. The series is edited by Dr. José Manuel Lorenzo and authored by a team of global experts in the fields of Food Quality and Safety, providing comprehensive knowledge to food industry personals and scientists.
Livestock Genome Editing Tools
1st Edition
Kui Li + 1 more
English
Livestock Genome Editing Tools introduces applications and improvements to a series of new genome editing techniques in livestock, such as pigs, cattle, and sheep. These tools include zinc finger nucleases (ZFN), transcription activator–like effector nucleases (TALEN), and the clustered regularly interspaced short palindromic repeats (CRISPR/Cas9) system, as well as the traditional gene targeting tools. The book also summarizes a series of genome editing–related techniques, including microinjection and somatic cell nuclear transfer.Written by international experts who have been working on livestock genetic editing field for more than 30 years, this book provides extensively theoretical and practical experience for readers to master the latest developments. This book explores the importance of research and application, as well as operation procedures, of livestock genetic editing tools. The writing of operation details makes this book an accessible read.This book is an important resource for researchers interested in genome-edited animals and scientists and technicians in breeding institutions and is also of interest to students major in animal reproduction and biological engineering.
Protein Digestion-Derived Peptides
Chemistry, Bioactivity, and Health Effects
1st Edition
Cristina Martinez-Villaluenga + 1 more
English
Protein Digestion-Derived Peptides: Chemistry, Bioactivity, and Health Effects presents the latest international advances in fundamental and applied research on the impact of gastrointestinal digestion on the release of bioactive peptides from food sources.This book covers the fundamentals and applications of gastrointestinal digestion and absorption models as well as the impact of food matrices, their components and protein characteristics, and peptide bioactivity, bioaccessibility, and bioavailability. Moreover, the book expands coverage in vitro and in vivo approaches to simulate gastrointestinal digestion of food proteins and absorption models to evaluate the bioaccessibility and bioavailability of released peptides.Developed for nutrition researchers, food scientists, and pharmaceutical scientists, this book is a welcomed resource for those who wish to understand the impact of peptides on chronic disease.
Advances in Agronomy
1st Edition
Volume 185
English
Advances in Agronomy, Volume 185, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.
Ethics in Online AI-Based Systems
Risks and Opportunities in Current Technological Trends
1st Edition
Santi Caballé + 2 more
English
Ethics in Online AI-Based Systems: Risks and Opportunities in Current Technological Trends creates a space to explore the ethical relevance that new technologies under development may have. Stimulating reflection and considerations with respect to the design, deployment, and use of technology helps readers guide current and future technological advancements from an ethically informed position to ensure that such advancements contribute towards solving current global and social challenges that we, as a society, have today. This will not only be useful for researchers and professional engineers, but also for educators, policy makers, and ethicists.Recent technological advancements have deeply transformed society and the way people interact with each other. Instantaneous communication platforms have allowed connections with other people, forming global communities and creating unprecedented opportunities in many sectors, making access to online resources more ubiquitous by reducing limitations imposed by geographical distance and temporal constrains. These technological developments bear ethically relevant consequences with their deployment, and legislations often lag behind such advancements. Because the appearance and deployment of these technologies happen much faster than legislative procedures, the way these technologies affect social interactions have profound ethical effects before any legislative regulation can be built in order to prevent and mitigate those effects.
Liposomes in Drug Delivery
What, Where, How and When to deliver
1st Edition
Sophia G. Antimisiaris
English
Liposomes in Drug Delivery: What, Where, How and When to Deliver is a concise, well-structured reference covering all the important issues related to the potential of this technology. Organized to provide practical information to researchers from any discipline with a particular therapeutic or bio-active substance to deliver, this book helps readers understand if liposomes can be of benefit for their particular need, what is the best type of liposome to use according to what needs to be delivered, where/when to deliver it, and how to design/prepare/chara... liposome properties for a particular application.The book is structured in Four parts. The first covers in a concise but in-depth way, what liposomes are, which are the liposome types, advantages/disadvant... and what is their stability, characterization methods, in vitro stability, and in vivo fate after different administration methods (routes). The second part focuses on the different mechanisms for liposomal drug delivery. Methodologies/techno... for manipulation of liposome structure/properties in order to design liposomes for particular delivery applications. Specific roadmaps for liposome design are discussed, including components to incorporate in liposomes for specific types of encapsulated molecules or specific routes of administration. The third part covers liposome applications for drug delivery. It focuses on specific delivery considerations for particular diseases. Finally, the fourth part covers methods of liposome fabrication.
Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy
1st Edition
Vivek Asati + 1 more
English
Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy discusses recently developed treatments based on molecular targets which are genetically altered in cancer cells and are essential for tumor development and survival. Considerable research effort has been devoted to the development of targeted drugs that inhibit the action of pathogenic kinases, and clinical studies performed so far have validated the positive effects of kinase inhibitors for cancer treatment. Each chapter discusses a molecular target, such as ALK2, ATR, CK, Src-Abl, EGFR, Fyn-Blk-Lyn, IGFs, and PAK1.The book's chapters are written by experts who actively work on the targets to help readers fully understand how they can be used. This is a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of novel cancer therapies based on molecular targets.
Microbial Biofilms
Role in Human Infectious Diseases
1st Edition
Mukesh Kumar Yadav + 2 more
English
Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases recovery time, but also escalates the cost of disease management. Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms. In addition, the close proximity of microbes within biofilms promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and leading to an increased prevalence of diseases associated with resistance. Fortunately, with advances in science and technology, novel strategies are being utilized to mitigate the impact of biofilms on human health.Microbial Biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research. It explores topics such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections, and the escalation of antimicrobial resistance determinants.
Sinusoidal Cells in Liver Diseases
Role in their Pathophysiology, Diagnosis, and Treatment
1st Edition
Jordi Gracia-Sancho
English
Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers, and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics.Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure.

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